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TrkA (NTRK1) (NM_002529) Human Untagged Clone
CAT＃: SC315454
NTRK1 (untagged)-Human neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 2
CNY 5,840.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MTC; p140-TrkA; TRK; Trk-A; TRK1; TRKA |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_002529 edited
ATGCTGCGAGGCGGACGGCGCGGGCAGCTTGGCTGGCACAGCTGGGCTGCGGGGCCGGGC AGCCTGCTGGCTTGGCTGATACTGGCATCTGCGGGCGCCGCACCCTGCCCCGATGCCTGC TGCCCCCACGGCTCCTCGGGACTGCGATGCACCCGGGATGGGGCCCTGGATAGCCTCCAC CACCTGCCCGGCGCAGAGAACCTGACTGAGCTCTACATCGAGAACCAGCAGCATCTGCAG CATCTGGAGCTCCGTGATCTGAGGGGCCTGGGGGAGCTGAGAAACCTCACCATCGTGAAG AGTGGTCTCCGTTTCGTGGCGCCAGATGCCTTCCATTTCACTCCTCGGCTCAGTCGCCTG AATCTCTCCTTCAACGCTCTGGAGTCTCTCTCCTGGAAAACTGTGCAGGGCCTCTCCTTA CAGGAACTGGTCCTGTCGGGGAACCCTCTGCACTGTTCTTGTGCCCTGCGCTGGCTACAG CGCTGGGAGGAGGAGGGACTGGGCGGAGTGCCTGAACAGAAGCTGCAGTGTCATGGGCAA GGGCCCCTGGCCCACATGCCCAATGCCAGCTGTGGTGTGCCCACGCTGAAGGTCCAGGTG CCCAATGCCTCGGTGGATGTGGGGGACGACGTGCTGCTGCGGTGCCAGGTGGAGGGGCGG GGCCTGGAGCAGGCCGGCTGGATCCTCACAGAGCTGGAGCAGTCAGCCACGGTGATGAAA TCTGGGGGTCTGCCATCCCTGGGGCTGACCCTGGCCAATGTCACCAGTGACCTCAACAGG AAGAACGTGACGTGCTGGGCAGAGAACGATGTGGGCCGGGCAGAGGTCTCTGTTCAGGTC AACGTCTCCTTCCCGGCCAGTGTGCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGC ATCCCCTTCTCTGTGGATGGGCAGCCGGCACCGTCTCTGCGCTGGCTCTTCAATGGCTCC GTGCTCAATGAGACCAGCTTCATCTTCACTGAGTTCCTGGAGCCCGCAGCCAATGAGACC GTGCGGCACGGGTGTCTGCGCCTCAACCAGCCCACCCACGTCAACAACGGCAACTACACG CTGCTGGCTGCCAACCCCTTCGGCCAGGCCTCCGCCTCCATCATGGCTGCCTTCATGGAC AACCCTTTCGAGTTCAACCCCGAGGACCCCATCCCTGTCTCCTTCTCGCCGGTGGACACT AACAGCACATCTGGAGACCCGGTGGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTG GCTGTGGGCCTGGCCGTCTTTGCCTGCCTCTTCCTTTCTACGCTGCTCCTTGTGCTCAAC AAATGTGGACGGAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTGGCTCCAGAGGAT GGGCTGGCCATGTCCCTGCATTTCATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAG GGCAAAGGCTCTGGGCTCCAAGGCCACATCATCGAGAACCCACAATACTTCAGTGATGCC TGTGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTGGGGGAGGGCGCC TTTGGGAAGGTCTTCCTTGCTGAGTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTG GTGGCTGTCAAGGCACTGAAGGAGGCGTCCGAGAGTGCTCGGCAGGACTTCCAGCGTGAG GCTGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTCGGCGTCTGCACC GAGGGCCGCCCCCTGCTCATGGTCTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTC CTCCGATCCCATGGACCTGATGCCAAGCTGCTGGCTGGTGGGGAGGATGTGGCTCCAGGC CCCCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCGGGGATGGTGTAC CTGGCGGGTCTGCATTTTGTGCACCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAG GGACTGGTGGTCAAGATTGGTGATTTTGGCATGAGCAGGGATATCTACAGCACCGACTAT TACCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCCGAGAGCATCCTG TACCGTAAGTTCACCACCGAGAGCGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATC TTCACCTACGGCAAGCAGCCCTGGTACCAGCTCTCCAACACGGAGGCAATCGACTGCATC ACGCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTCTACGCCATCATG CGGGGCTGCTGGCAGCGGGAGCCCCAGCAACGCCACAGCATCAAGGATGTGCACGCCCGG CTGCAAGCCCTGGCCCAGGCACCTCCTGTCTACCTGGATGTCCTGGGCTAG >Reverse primer walk for NM_002529 unedited
GGGGNCCCACTACGTTCGTGCCCCCACTNCCACCGNAGNNCATTGGGCACCTGGNACCTT CAGCGTGGGCACACCACAGCTGGCATTGGGCATGTGGGCCAGGGGCCCTTGCCCATGACA CTGCAGCTTCTGTTCAGGCACTCCGCCCAGTCCCTCCTCCTCCCAGCGCTGTAGCCAGCG CAGGGCACAAGAACAGTGCAGAGGGTTCCCCGACAGGACCAGTTCCTGTAAGGAGAGGCC CTGCACAGTTTTCCAGGAGAGAGACTCCAGAGCGTTGAAGGAGAGATTCAGGCGACTGAG CCGAGGAGTGAAATGGAAGGCATCTGGCGCCACGAAACGGAGACCACTCTTCACGATGGT GAGGTTTCTCAGCTCCCCCAGGCCCCTCAGATCACGGAGCTCCAGATGCTGCAGATGCTG CTGGTTCTCGATGTAGAGCTCAGTCAGGTTCTCTGCGCCGGGCAGGTGGTGGAGGCTATC CAGGGCCCCATCCCGGGTGCATCGCAGTCCCGAGGAGCCGTGGGGGCAGCAGGCATCGGG GCAGGGTGCGGCGCCCGCAGATGCCAGTATCAGCCAAGCCAGCAGGCTGCCCGGCCCCGC AGCCCAGCTGTGCCAGCCAAGCTGCCCGCGCCGTCCGCCTCGCAGCATGCGGCCGCCCTA TAGTGAGTCGTATTACANAATTCTGACGGTTCACTAAACGAGCTCTGCTTATATAGACCT CCCACCGTACACGCCCTACCGCCCATTTGCGTCAACGGGGCGGGGTTATTACGACATTTT GGGAAAGTCCCCGTGATTTTTGGTGCCAAAACAAACTNCCATTGGACGTCATGGGTTGGA GACTTGGAAATCCCCGTGAGTCAAACCGCTATCCAGCCCCATTGGTGTACTGCCCAAACC GATCAACCTGGTAATAGCGA >OriGene 3' read for NM_002529 unedited
GGCAATGGGGAGGCAACTTCCAGGCCAGNATAGCACTGGGGAGGGTACAGGGATGCCCCC GGGACGTTCAGAAACAGCTATGACCGCGGCCGCAATCTAGAGCGTCACGAGCTAGCCCAG GACATCCAGGTAGACAGGAGGTGCCTGGGCCAGGGCTTGCAGCCGGGCGTGCACATCCTT GATGCTGTGGCGTTGCTGGGGCTCCCGCTGCCAGCAGCCCCGCATGATGGCGTAGACCTC TGGTGGGCAGGCACGTGGCCGCTCCAACTCACGTCCCTGCGTGATGCAGTCGATTGCCTC CGTGTTGGAGAGCTGGTACCAGGGCTGCTTGCCGTAGGTGAAGATCTCCCAGAGCACCAC GCCGAAGCTCCACACGTCGCTCTCGGTGGTGAACTTACGGTACAGGATGCTCTCGGGCGG CATCCAGCGAATGGGCAGCATGGTGCGGCCTCCCACACGGTAATAGTCGGTGCTGTAGAT ATCCCTGCTCATGCCAAAATCACCAATCTTGACCCACCAGTCCCTGNCCCACTAGACAGT TTGCGTGTGGCCAGGTCCCGGTGCACANAATGCAGACCCGCCAGGTACACCATCCCCGCA GCGACCTGGCTAGCCANCGGGGGGCNAGCACCTGCCCAAACCCAGGGGGCCTGGACCCCC ATTCTCCCCACAACCAAAACTTGGAATTAGTCCATGGAATCNNNNNAAGAAAAAAAAACC CCTTTGTAGTCCCCTCTGGCCGCCATTTCTCTAAAAACTATAGCCGGGGGGGGCCCCTCT TGGGCCAACCCCCCAAAAACCCCCAAGTGTGTTGGTTTTCCCCCGTGGGAAAAACCCCCA CCCCCCCCCCGGAAAATCCTGGGAAAAACTTTTGGGACCCTCTTTTTTTTGG |
| Restriction Sites | Please inquire |
| ACCN | NM_002529 |
| Insert Size | 2400 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002529.3, NP_002520.2 |
| RefSeq Size | 2663 bp |
| RefSeq ORF | 2391 bp |
| Locus ID | 4914 |
| UniProt ID | P04629 |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Apoptosis, Endocytosis, MAPK signaling pathway, Neurotrophin signaling pathway, Pathways in cancer, Thyroid cancer |
| Gene Summary | This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) represents the longest transcript and encodes the longest isoform (2). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213047 | NTRK1 (Myc-DDK-tagged)-Human neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 2 |
CNY 5,832.00 |
|
| RC213047L1 | Lenti ORF clone of Human neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 2, Myc-DDK-tagged |
CNY 8,232.00 |
|
| RC213047L2 | Lenti ORF clone of Human neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 2, mGFP tagged |
CNY 10,260.00 |
|
| RC213047L3 | Lenti ORF clone of Human neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 2, Myc-DDK-tagged |
CNY 8,232.00 |
|
| RC213047L4 | Lenti ORF clone of Human neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 2, mGFP tagged |
CNY 8,232.00 |
|
| RC600033 | NTRK1 (DDK-His-tagged)-Extra Cellular Domain Clone of Homo sapiens neurotrophic tyrosine kinase, receptor, type 1, transcript variant 2, Signal peptide (1-32) plus EC domain (33-423) |
CNY 3,656.00 |
|
| RG213047 | NTRK1 (tGFP-tagged) - Human neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 2 |
CNY 7,432.00 |
