RIN2 (NM_018993) Human Untagged Clone
CAT＃: SC314879
RIN2 (untagged)-Human Ras and Rab interactor 2 (RIN2)
CNY 17200.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MACS; RASSF4 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC314879 representing NM_018993.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGACAGCTTGGACCATGGGCGCCCGCGGTCTGGACAAGCGAGGAAGTTTCTTTAAGCTCATTGACACA ATTGCCTCGGAGATCGGAGAACTGAAACAGGAGATGGTGCGGACAGATGTCAACCTGGAAAATGGCCTG GAACCCGCTGAAACCCACAGCATGGTAAGACACAAGGATGGTGGCTATTCCGAGGAAGAGGACGTGAAG ACCTGTGCCCGGGACTCAGGCTATGACAGCCTCTCCAACAGGCTCAGCATCTTGGACCGGCTCCTCCAC ACCCACCCCATATGGCTGCAGCTGAGTCTGAGTGAGGAGGAGGCAGCAGAGGTCCTGCAGGCCCAGCCT CCGGGGATCTTCCTGGTTCATAAATCTACCAAGATGCAGAAGAAAGTCCTCTCCCTCCGCCTGCCCTGT GAATTTGGGGCCCCACTCAAGGAATTTGCCATAAAGGAAAGCACATACACCTTTTCCCTGGAAGGCTCA GGAATCAGTTTCGCAGATTTATTCCGGCTCATTGCTTTCTACTGCATCAGCAGGGATGTTCTACCATTT ACCTTGAAGTTGCCTTATGCCATTTCAACAGCCAAGTCGGAGGCTCAGCTTGAAGAACTGGCCCAGATG GGACTAAATTTCTGGAGCTCCCCAGCTGACAGCAAACCCCCGAACCTTCCACCTCCCCATAGGCCTCTT TCCTCCGACGGTGTCTGTCCTGCCTCCCTGCGTCAGCTCTGCCTTATAAATGGAGTGCATTCTATCAAA ACCAGGACGCCTTCAGAGCTGGAGTGCAGCCAGACCAACGGGGCCCTGTGCTTTATTAATCCCCTTTTC TTGAAAGTGCACAGCCAGGACCTCAGTGGAGGCCTGAAACGGCCGAGCACAAGGACTCCCAACGCGAAT GGCACGGAGCGGACTCGGTCCCCCCCACCCAGGCCCCCGCCACCCGCTATTAATAGTCTCCACACAAGC CCTCGGCTGGCCAGGACTGAAACCCAGACGAGCATGCCAGAAACAGTCAACCATAACAAACATGGGAAC GTAGCTCTGCCTGGAACGAAACCAACTCCCATCCCTCCACCCCGGCTGAAGAAGCAGGCTTCTTTTCTG GAAGCAGAGGGCGGTGCAAAGACCTTGAGCGGCGGCCGGCCGGGCGCAGGCCCGGAGCTGGAGCTGGGC ACAGCTGGCAGCCCAGGTGGGGCCCCGCCTGAGGCCGCCCCGGGGGATTGCACAAGGGCCCCGCCGCCC AGCTCTGAATCACGGCCCCCGTGCCATGGAGGCCGGCAGCGGCTGAGCGACATGAGCATTTCTACTTCC TCCTCCGACTCGCTGGAGTTCGACCGGAGCATGCCTCTGTTTGGCTACGAGGCGGACACCAACAGCAGC CTGGAGGACTACGAGGGGGAAAGTGACCAAGAGACCATGGCGCCCCCCATCAAGTCCAAAAAGAAAAGG AGCAGCTCCTTCGTGCTGCCCAAGCTCGTCAAGTCCCAGCTGCAGAAGGTGAGCGGGGTGTTCAGCTCC TTCATGACCCCGGAGAAGCGGATGGTCCGCAGGATCGCCGAGCTTTCCCGGGACAAATGCACCTACTTC GGGTGCTTAGTGCAGGACTACGTGAGCTTCCTGCAGGAGAACAAGGAGTGCCACGTGTCCAGCACCGAC ATGCTGCAGACCATCCGGCAGTTCATGACCCAGGTCAAGAACTATTTGTCTCAGAGCTCGGAGCTGGAC CCCCCCATCGAGTCGCTGATCCCTGAAGACCAAATAGATGTGGTGCTGGAAAAAGCCATGCACAAGTGC ATCTTGAAGCCCCTCAAGGGGCACGTGGAGGCCATGCTGAAGGACTTTCACATGGCCGATGGCTCATGG AAGCAACTCAAGGAGAACCTGCAGCTTGTGCGGCAGAGGAATCCGCAGGAGCTGGGGGTCTTCGCCCCG ACCCCTGATTTTGTGGATGTGGAGAAAATCAAAGTCAAGTTCATGACCATGCAGAAGATGTATTCGCCG GAAAAGAAGGTCATGCTGCTGCTGCGGGTCTGCAAGCTCATTTACACGGTCATGGAGAACAACTCAGGG AGGATGTATGGCGCTGATGACTTCTTGCCAGTCCTGACCTATGTCATAGCCCAGTGTGACATGCTTGAA TTGGACACTGAAATCGAGTACATGATGGAGCTCCTAGACCCATCGCTGTTACATGGAGAAGGAGGCTAT TACTTGACAAGCGCATATGGAGCACTTTCTCTGATAAAGAATTTCCAAGAAGAACAAGCAGCGCGACTG CTCAGCTCAGAAACCAGAGACACCCTGAGGCAGTGGCACAAACGGAGAACCACCAACCGGACCATCCCC TCTGTGGACGACTTCCAGAATTACCTCCGAGTTGCATTTCAGGAGGTCAACAGTGGTTGCACAGGAAAG ACCCTCCTTGTGAGACCTTACATCACCACTGAGGATGTGTGTCAGATCTGCGCTGAGAAGTTCAAGGTG GGGGACCCTGAGGAGTACAGCCTCTTTCTCTTCGTTGACGAGACATGGCAGCAGCTGGCAGAGGACACT TACCCTCAAAAAATCAAGGCGGAGCTGCACAGCCGACCACAGCCCCACATCTTCCACTTTGTCTACAAA CGCATCAAGAACGATCCTTATGGCATCATTTTCCAGAACGGGGAAGAAGACCTCACCACCTCCTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_018993 |
| Insert Size | 2688 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_018993.3 |
| RefSeq Size | 4265 bp |
| RefSeq ORF | 2688 bp |
| Locus ID | 54453 |
| UniProt ID | Q8WYP3 |
| Domains | RA, VPS9 |
| MW | 100.2 kDa |
| Gene Summary | The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011] Transcript Variant: This variant (2) lacks a portion of the 5' UTR and 5' coding region, and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213759 | RIN2 (Myc-DDK-tagged)-Human Ras and Rab interactor 2 (RIN2) |
CNY 6552.00 |
|
| RC213759L3 | Lenti ORF clone of Human Ras and Rab interactor 2 (RIN2), Myc-DDK-tagged |
CNY 9030.00 |
|
| RC213759L4 | Lenti ORF clone of Human Ras and Rab interactor 2 (RIN2), mGFP tagged |
CNY 9030.00 |
|
| RG213759 | RIN2 (tGFP-tagged) - Human Ras and Rab interactor 2 (RIN2) |
CNY 8152.00 |
