C2CD3 (AK092089) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	OFD14
Vector	pCMV6 series
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for AK092089, the custom clone sequence may differ by one or more nucleotides ATGAAACAACGAAAAGGCCAAGGGTCTGGGGGCAGCCGTGGGCGCAAAAAAAGAGGTTTA AGTGACATTTCTCCATCTACAAGCCTGCCACCTCTGGTTGAAGGCCAGCTACGCTGTTTT CTAAAACTTACTGTTAATAGAGTCATATGGAAGATTGCAAAGCCTCCCACTTGTGTACTT GTCCGAGTGAGATGGTGGGGAGAAACATCAGATGGAACCCTCTTTTGTCCCAGGGATGCA TTGCAGACTGAACCAAAAGCTGTGAGAACAACTACACGTTACGCTATTCGTTGTGGTCCA AAACAGTTTACCTCTTATCTAACAGATATGGCTGTGCTGGTGCTGGAAGTAATCACCAAA CTTGATGGTCTTCCAATTGGTAGAGTTCAGATCAATGGACTAGCTCAACTTTCTCCAACC CATCAAATCAATGGATTTTTTACCATTGTTTCATCAACGTCTAAGAAACTTGGAGAACTC CAGGTCTCACTTGCCCTGGAACCTCTGTCAGAAACTTACGACAGCTACCATCCACTTCCT ACCACTGACATGACAGAAAATGTGCTTTTATCTAAGCAGGGATTCAGAGAGAATACTGAA CCCAGCAGTACCCAGTTTCAGGTTCCATCAAGGCCTCGCGACATACATACCATCAAAATT GATGGAAAAGAGTTAGCAGCCAACAGCAGTAGATCAACCACTCCGAGGGGAAAAGACCAT GTATGCTTTGCAGAGAACCCTGATACAATAAAGGATTCTTCCTTTGGACTACAGCACAGT CTTAATTCAGGACAGAGTTTAGAGTCTGTAACTCTGAAAGGCAGAGCTCCACGGAAGCAG ATGTCCCTTCTGAACAGTTCTGAATTCCAGCCTCAAATTAGAACAGTTGCCAAGAGTCAC AGTGACTCATGCATTCTTTCTTCAAACAACCTCCCTACCAAGGATCTTCTTTCAGCTCTG TTAGAACAAGGCAATAAACTGCGTAATGCCATGGTGATTTCTGCAATGAAATCAAGCCCA GAGACCAGCATGTTGTTGGACCAAGTTCATCCTCTATTAATGAAGATTCTCTTAGAGCAT CAACACAGATCAGAGCCTTTTCTAGGAATCGGTTTAAAGACCACATTGAAGATCACCTCC TCCCTTCAACTGAGAATACATTTTGGAGACATGACACAAAAGCTGATACCAGAGCTATAC AGCTGCTAT
Restriction Sites	Please inquire
ACCN	AK092089
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	AK092089.1, BAC03802.1
RefSeq Size	2586 bp
RefSeq ORF	2586 bp
Locus ID	26005
Gene Summary	This gene encodes a protein that functions as a regulator of centriole elongation. Studies of the orthologous mouse protein show that it promotes centriolar distal appendage assembly and is also required for the recruitment of other ciliogenic proteins, including intraflagellar transport proteins. Mutations in this gene cause orofaciodigital syndrome XIV (OFD14), a ciliopathy resulting in malformations of the oral cavity, face and digits. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014]

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