CD22 (NM_001771) Human Untagged Clone
CAT＃: SC311315
CD22 (untagged)-Human CD22 molecule (CD22), transcript variant 1
CNY 9312.00
Product images
CNY 1999.00
CNY 2700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SIGLEC-2; SIGLEC2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001771 edited
GGCCGAGACACGGTGCAGTGCCTGTGCGTGGTGAAGTCCAACCCGGAGCCGTCCGTGGCC TTTGAGCTGCCATCGCGCAATGTGACCGTGAACGAGAGCGAGCGGGAGTTCGTGTACTCG GAGCGCAGCGGCCTCGTGCTCACCAGCATCCTCACGCTGCGGGGGCAGGCCCAGGCCCCG CCCCGCGTCATCTGCACCGCGAGGAACCTCTATGGCGCCAAGAGCCTGGAGCTGCCCTTC CAGGGAGCCCATCGACTGATGTGGGCCAAGATCGGGCCTGTGGGCGCCGTGGTCGCCTTT GCCATCCTGATTGCCATCGTCTGCTACATTACCCAGACACGCAGGAAAAAGAACGTGACA GAGAGCCCCAGCTTCTCGGCAGGGGACAACCCTCCCGTCCTGTTCAGCAGCGACTTCCGC ATCTCTGGGGCACCAGAGAAGTACGAGATGCTGCCAGGGTCCCTGAAGAGGGAAGACACG CGGAAACAGGCTTGCACCCAGACACGACACCATGCATCTCCTCGGCCCCTGGCTCCTGCT CCTGGTTCTAGAATACTTGGCTTTCTCTGACTCAAGTAAATGGGTTTTTGAGCACCCTGA AACCCTCTACGCCTGGGAGGGGGCCTGCGTCTGGATCCCCTGCACCTACAGAGCCCTAGA TGGTGACCTGGAAAGCTTCATCCTGTTCCACAATCCTGAGTATAACAAGAACACCTCGAA GTTTGATGGGACAAGACTCTATGAAAGCACAAAGGATGGGAAGGTTCCTTCTGAGCAGAA AAGGGTGCAATTCCTGGGAGACAAGAATAAGAACTGCACACTGAGTATCCACCCGGTGCA CCTCAATGACAGTGGTCAGCTGGGGCTGAGGATGGAGTCCAAGACTGAGAAATGGATGGA ACGAATACACCTCAATGTCTCTGAAAGGCCTTTTCCACCTCATATCCAGCTCCCTCCAGA AATTCAAGAGTCCCAGGAAGTCACTCTGACCTGCTTGCTGAATTTCTCCTGCTATGGGTA TCCGATCCAATTGCAGTGGCTCCTAGAGGGGGTTCCAATGAGGCAGGCTGCTGTCACCTC GACCTCCTTGACCATCAAGTCTGTCTTCACCCGGAGCGAGCTCAAGTTCTCCCCACAGTG GAGTCACCATGGGAAGATTGTGACCTGCCAGCTTCAGGATGCAGATGGGAAGTTCCTCTC CAATGACACGGTGCAGCTGAACGTGAAGCACACCCCGAAGTTGGAGATCAAGGTCACTCC CAGTGATGCCATAGTGAGGGAGGGGGACTCTGTGACCATGACCTGCGAGGTCAGCAGCAG CAACCCGGAGTACACGACGGTATCCTGGCTCAAGGATGGGACCTCGCTGAAGAAGCAGAA TACATTCACGCTAAACCTGCGCGAAGTGACCAAGGACCAGAGTGGGAAGTACTGCTGTCA GGTCTCCAATGACGTGGGCCCGGGAAGGTCGGAAGAAGTGTTCCTGCAAGTGCAGTATGC CCCGGAACCTTCCACGGTTCAGATCCTCCACTCACCGGCTGTGGAGGGAAGTCAAGTCGA GTTTCTTTGCATGTCACTGGCCAATCCTCTTCCAACAAATTACACGTGGTACCACAATGG GAAAGAAATGCAGGGAAGGACAGAGGAGAAAGTCCACATCCCAAAGATCCTCCCCTGGCA CGCTGGGACTTATTCCTGTGTGGCAGAAAACATTCTTGGTACTGGACAGAGGGGCCCGGG AGCTGAGCTGGATGTCCAGTATCCTCCCAAGAAGGTGACCACAGTGATTCAAAACCCCAT GCCGATTCGAGAAGGAGACACAGTGACCCTTTCCTGTAACTACAATTCCAGTAACCCCAG TGTTACCCGGTATGAATGGAAACCCCATGGCGCCTGGGAGGAGCCATCGCTTGGGGTGCT GAAGATCCAAAACGTTGGCTGGGACAACACAACCATCGCCTGCGCAGCTTGTAATAGTTG GTGCTCGTGGGCCTCCCCTGTCGCCCTGAATGTCCAGTATGCCCCCCGAGACGTGAGGGT CCGGAAAATCAAGCCCCTTTCCGAGATTCACTCTGGAAACTCGGTCAGCCTCCAATGTGA CTTCTCAAGCAGCCACCCCAAAGAAGTCCAGTTCTTCTGGGAGAAAAATGGCAGGCTTCT GGGGAAAGAAAGCCAGCTGAATTTTGACTCCATCTCCCCAGAAGATGCTGGGAGTTACAG CTGCTGGGTGAACAACTCCATAGGACAGACAGCGTCCAAGGCCTGGACACTTGAAGTGCT GTATGCACCCAGGAGGCTGCGTGTGTCCATGAGCCCGGGGGACCAAGTGATGGAGGGGAA GAGTGCAACCCTGACCTGTGAGAGCGACGCCAACCCTCCCGTCTCCCACTACACCTGGTT TGACTGGAATAACCAAAGCCTCCCCTACCACAGCCAGAAGCTGAGATTGGAGCCGGTGAA GGTCCAGCACTCGGGTGCCTACTGGTGCCAGGGGACCAACAGTGTGGGCAAGGGCCGTTC GCCTCTCAGCACCCTCACCGTCTACTATAGCCCGGAGACCATCGGCAGGCGAGTGGCTGT GGGACTCGGGTCCTGCCTCGCCATCCTCATCCTGGCAATCTGTGGGCTCAAGCTCCAGCG ACGTTGGAAGAGGACACAGAGCCAGCAGGGGCTTCAGGAGAATTCCAGCGGCCAGAGCTT CTTTGTGAGGAATAAAAAGGTTAGAAGGGCCCCCCTCTCTGAAGGCCCCCACTCCCTGGG ATGCTACAATCCAATGATGGAAGATGGCATTAGCTACACCACCCTGCGCTTTCCCGAGAT GAACATACCACGAACTGGAGATGCAGAGTCCTCAGAGATGCAGAGACCTCCCCCGGACTG CGATGACACGGTCACTTATTCAGCATTGCACAAGCGCCAAGTGGGCGACTATGAGAACGT CATTCCAGATTTTCCAGAAGATGAGGGGATTCATTACTCAGAGCTGATCCAGTTTGGGGT CGGGGAGCGGCCTCAGGCACAAGAAAATGTGGACTATGTGATCCTCAAACATTGACACTG GATGGGCTGCAGCAGAGGCACTGGGGGCAGCGGGGGCCAGGGAAGTCCCCGAGTTTCCCC AGACACCGCCACATGGCTTCCTCCTGCGCGCATGTGCGCACACACACACACACACGCACA CACACACACACACACTCACTGCGGAGAACCTTGTGCCTGGCTCAGAGCCAGTCTTTTTGG TGAGGGTAACCCCAAACCTCCAAAACTCCTGCCCCTGTTCTCTTCCACTCTCCTTGCTAC CCAGAAATCCATCTAAATACCTGCCCTGACATGCACACCTCCCCCTGCCCCCACCACGGC CACTGGCCATCTCCACCCCCAGCTGCTTGTGTCCCTCCTGGGATCTGCTCGTCATCATTT TTCCTTCCCTTCTCCATCTCTCTGGCCCTCTACCCCTGATCTGACATCCCCACTCACGAA TATTATGCCCAGTTTCTGCCTCTGAGGGAAAGCCCAGAAAAGGACAGAAACGAAGTAGAA AGGGGCCCAGTCCTGGCCTGGCTTCTCCTTTGGAAGTGAGGCATTGCACGGGGAGACGTA CGTATCAGCGGCCCCTTGACTCTGGGGACTCCGGGTTTGAGATGGACACACTGGTGTGGA TTAACCTGCCAGGGAGACAGAGCTCACAATAAAAATGGCTCAGATGCCACTTCAAAAAAA AAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001771 |
| Insert Size | 3700 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to contain 4 SNPs compared with NM_001771.1. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001771.1, NP_001762.1 |
| RefSeq Size | 3260 bp |
| RefSeq ORF | 2544 bp |
| Locus ID | 933 |
| UniProt ID | P20273 |
| Domains | ig, IGc2, IG |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage |
| Gene Summary | Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216939 | CD22 (Myc-DDK-tagged)-Human CD22 molecule (CD22), transcript variant 1 |
CNY 9304.00 |
|
| RC216939L1 | Lenti-ORF clone of CD22 (Myc-DDK-tagged)-Human CD22 molecule (CD22), transcript variant 1 |
CNY 11704.00 |
|
| RC216939L2 | Lenti-ORF clone of CD22 (mGFP-tagged)-Human CD22 molecule (CD22), transcript variant 1 |
CNY 11704.00 |
|
| RC216939L3 | Lenti-ORF clone of CD22 (Myc-DDK-tagged)-Human CD22 molecule (CD22), transcript variant 1 |
CNY 11704.00 |
|
| RC216939L4 | Lenti-ORF clone of CD22 (mGFP-tagged)-Human CD22 molecule (CD22), transcript variant 1 |
CNY 11704.00 |
|
| RG216939 | CD22 (tGFP-tagged) - Human CD22 molecule (CD22), transcript variant 1 |
CNY 10904.00 |
