PHF15 (JADE2) (NM_015288) Human Untagged Clone
CAT＃: SC310110
PHF15 (untagged)-Human PHD finger protein 15 (PHF15)
CNY 15200.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | JADE-2; PHF15 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC310110 representing NM_015288.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGAAGAGAAGAGGCGAAAATACTCCATCAGCAGTGACAACTCTGACACCACTGACAGTCATGCGACA TCTACATCCGCATCAAGATGCTCCAAACTGCCCAGCAGCACCAAGTCGGGCTGGCCCCGACAGAACGAA AAGAAGCCCTCCGAGGTTTTCCGGACAGACTTGATCACAGCCATGAAGATCCCGGACTCATACCAGCTC AGCCCGGATGACTACTACATCCTGGCAGACCCATGGCGACAGGAATGGGAGAAAGGTGTGCAGGTGCCT GCCGGGGCAGAGGCCATCCCAGAGCCCGTGGTGAGGATCCTCCCACCACTGGAAGGCCCCCCTGCCCAG GCATCCCCGAGCAGCACCATGCTTGGTGAGGGCTCCCAGCCTGATTGGCCAGGGGGCAGCCGCTATGAC TTGGACGAGATTGATGCCTACTGGCTGGAGCTCATCAACTCGGAGCTTAAGGAGATGGAGAGGCCGGAG CTGGACGAGCTGACATTAGAGCGTGTGCTGGAGGAGCTGGAGACCCTGTGCCACCAGAATATGGCCAGG GCCATTGAGACGCAGGAGGGGCTGGGCATCGAGTACGACGAGGATGTTGTCTGCGACGTGTGTCGCTCT CCTGAGGGCGAGGATGGCAACGAGATGGTCTTCTGTGACAAGTGCAACGTCTGTGTGCATCAGGCATGC TACGGGATCCTCAAGGTGCCCACGGGCAGCTGGCTGTGCCGGACGTGTGCCCTGGGTGTCCAGCCAAAG TGCCTGCTCTGCCCCAAGCGAGGAGGAGCCTTGAAGCCCACTAGAAGTGGGACCAAGTGGGTGCATGTC AGCTGTGCCCTATGGATTCCTGAGGTCAGCATCGGCTGCCCAGAGAAGATGGAGCCCATCACCAAGATC TCGCATATCCCAGCCAGCCGCTGGGCTCTGTCCTGCAGCCTCTGCAAGGAATGCACAGGCACCTGCATC CAGTGTTCCATGCCTTCCTGCGTCACAGCGTTCCATGTCACATGCGCCTTTGACCACGGCCTGGAAATG CGGACTATATTAGCAGACAACGATGAGGTCAAGTTCAAGTCATTCTGCCAGGAGCACAGTGACGGGGGC CCACGTAATGAGCCCACATCTGAGCCCACGGAACCCAGCCAGGCTGGCGAGGACCTGGAAAAGGTGACC CTGCGCAAGCAGCGGCTGCAGCAGCTAGAGGAGGACTTCTACGAGCTGGTGGAGCCGGCTGAGGTGGCT GAGCGGCTGGACCTGGCTGAGGCACTGGTCGACTTCATCTACCAGTACTGGAAGCTGAAGAGGAAAGCC AATGCCAACCAGCCGCTGCTGACCCCCAAGACCGACGAGGTGGACAACCTGGCCCAGCAGGAGCAGGAC GTCCTCTACCGCCGCCTGAAGCTCTTCACCCATCTGCGGCAGGACCTAGAGAGGGTTAGAAATCTGTGC TACATGGTGACAAGGCGCGAGAGAACGAAACACGCCATCTGCAAACTCCAGGAGCAGATATTCCACCTG CAGATGAAACTTATTGAACAGGATCTGTGTCGAGGCCTGTCCACCTCATTCCCCATCGATGGCACCTTC TTCAACAGCTGGCTGGCACAGTCGGTGCAGATCACAGCAGAGAACATGGCCATGAGCGAGTGGCCACTG AACAATGGGCACCGCGAGGACCCTGCTCCAGGGCTGCTGTCAGAGGAACTGCTGCAGGACGAGGAGACA CTGCTCAGCTTCATGCGGGACCCCTCGCTGCGACCTGGTGACCCTGCTAGGAAGGCCCGAGGCCGCACC CGCCTGCCTGCCAAGAAGAAACCACCACCACCACCACCGCAGGACGGGCCTGGTTCACGGACGACTCCA GACAAAGCCCCCAAGAAGACCTGGGGCCAGGATGCAGGCAGTGGCAAGGGGGGTCAAGGGCCACCTACC AGGAAGCCACCACGTCGGACATCTTCTCACTTGCCGTCCAGCCCTGCAGCCGGGGACTGTCCCATCCTA GCCACCCCTGAAAGCCCCCCGCCACTGGCCCCTGAGACCCCGGACGAGGCAGCCTCAGTAGCTGCTGAC TCAGATGTCCAAGTGCCTGGCCCTGCAGCAAGCCCTAAGCCTTTGGGCCGGCTCCGGCCACCCCGCGAG AGCAAGGTAACCCGGAGATTGCCGGGTGCCAGGCCTGATGCTGGGATGGGACCACCTTCAGCTGTGGCT GAGAGGCCCAAGGTCAGCCTGCATTTTGACACTGAGACTGATGGCTACTTCTCTGATGGGGAGATGAGC GACTCAGATGTAGAGGCCGAGGACGGTGGGGTGCAGCGGGGTCCCCGGGAGGCAGGGGCAGAGGAGGTG GTCCGCATGGGCGTACTGGCCTCCTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_015288 |
| Insert Size | 2373 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_015288.5 |
| RefSeq Size | 6478 bp |
| RefSeq ORF | 2373 bp |
| Locus ID | 23338 |
| UniProt ID | Q9NQC1 |
| Protein Families | Druggable Genome, Transcription Factors |
| MW | 87.5 kDa |
| Gene Summary | Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo (PubMed:16387653). Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A (PubMed:25018020). Also acts as a ubiquitin ligase E3 toward itself. Positive regulator of neurogenesis (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (3) is shorter than isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202604 | PHF15 (Myc-DDK-tagged)-Human PHD finger protein 15 (PHF15) |
CNY 5792.00 |
|
| RC202604L1 | Lenti ORF clone of Human PHD finger protein 15 (PHF15), Myc-DDK-tagged |
CNY 8192.00 |
|
| RC202604L2 | Lenti ORF clone of Human PHD finger protein 15 (PHF15), mGFP tagged |
CNY 7700.00 |
|
| RC202604L3 | Lenti ORF clone of Human PHD finger protein 15 (PHF15), Myc-DDK-tagged |
CNY 7700.00 |
|
| RC202604L4 | Lenti ORF clone of Human PHD finger protein 15 (PHF15), mGFP tagged |
CNY 7700.00 |
|
| RG202604 | PHF15 (tGFP-tagged) - Human PHD finger protein 15 (PHF15) |
CNY 7392.00 |
|
| SC112639 | PHF15 (untagged)-ORIGENE UNIQUE VARIANT 1 of Human PHD finger protein 15 (PHF15) |
CNY 5792.00 |
