GRIK2 (NM_175768) Human Untagged Clone
CAT＃: SC310072
GRIK2 (untagged)-Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 2
CNY 6376.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EAA4; GLR6; GluK2; GLUK6; GLUR6; MRT6 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_175768 edited
ATTTCTCCCGGATGCTCTCCGACTAACATGGATGTCCCACCATTCCTTGCAGTGGAAGGT TGTTCCTTGGCGCAGTGAGTGAAGAACATGCAGCGATTGCTAATGGGTTTGGGAAGCGGA GACTCCTTCCTCTCTCTATGACCATGCCGTGATCGTGTCTGCGGTCACCACTCGACGCAT CCTCATTTCTACCCGAACCCAGGAGCCGAACGCTAGATCGGGGAAGTGGGTGCCGTGCGT GTGGGCACAGAAACACCATGAAGATTATTTTCCCGATTCTAAGTAATCCAGTCTTCAGGC GCACCGTTAAACTCCTGCTCTGTTTACTGTGGATTGGATATTCTCAAGGAACCACACATG TATTAAGATTTGGTGGTATTTTTGAATATGTGGAATCTGGCCCAATGGGAGCTGAGGAAC TTGCATTCAGATTTGCTGTGAACACAATTAACAGAAACAGAACATTGCTACCCAATACTA CCCTTACCTATGATACCCAGAAGATAAACCTTTATGATAGTTTTGAAGCATCCAAGAAAG CCTGTGATCAGCTGTCTCTTGGGGTGGCTGCCATCTTCGGGCCTTCACACAGCTCATCAG CAAACGCAGTGCAGTCCATCTGCAATGCTCTGGGAGTTCCCCACATACAGACCCGCTGGA AGCACCAGGTGTCAGACAACAAAGATTCCTTCTATGTCAGTCTCTACCCAGACTTCTCTT CACTCAGCCGTGCCATTTTAGACCTGGTGCAGTTTTTCAAGTGGAAAACCGTCACGGTTG TGTATGATGACAGCACTGGTCTCATTCGTTTGCAAGAGCTCATCAAAGCTCCATCAAGGT ATAATCTTCGACTCAAAATTCGTCAGTTACCTGCTGATACAAAGGATGCAAAACCCTTAC TAAAAGAAATGAAAAGAGGCAAGGAGTTTCATGTAATCTTTGATTGTAGCCATGAAATGG CAGCAGGCATTTTAAAACAGGCATTAGCTATGGGAATGATGACAGAATACTATCATTATA TCTTTACCACTCTGGACCTCTTTGCTCTTGATGTTGAGCCCTACCGATACAGTGGTGTTA ACATGACAGGGTTCAGAATATTAAATACAGAAAATACCCAAGTCTCCTCCATCATTGAAA AGTGGTCGATGGAACGATTGCAGGCACCTCCGAAACCCGATTCAGGTTTGCTGGATGGAT TTATGACGACTGATGCTGCTCTAATGTATGATGCTGTGCATGTGGTGTCTGTGGCCGTTC AACAGTTTCCCCAGATGACAGTCAGTTCCTTGCAGTGTAATCGACATAAACCCTGGCGCT TCGGGACCCGCTTTATGAGTCTAATTAAAGAGGCACATTGGGAAGGCCTCACAGGCAGAA TAACTTTCAACAAAACCAATGGCTTGAGAACAGATTTTGATTTGGATGTGATCAGTCTGA AGGAAGAAGGTCTAGAAAAGATTGGAACGTGGGATCCAGCCAGTGGCCTGAATATGACAG AAAGTCAAAAGGGAAAGCCAGCGAACATCACAGATTCCTTATCCAATCGTTCTTTGATTG TTACCACCATTTTGGAAGAGCCTTATGTCCTTTTTAAGAAGTCTGACAAACCTCTCTATG GTAATGATCGATTTGAAGGCTATTGCATTGATCTCCTCAGAGAGTTATCTACAATCCTTG GCTTTACATATGAAATTAGACTTGTGGAAGATGGGAAATATGGAGCCCAGGATGATGCCA ATGGACAATGGAATGGAATGGTTCGTGAACTAATTGATCATAAAGCTGACCTTGCAGTTG CTCCACTGGCTATTACCTATGTTCGAGAGAAGGTCATCGACTTTTCCAAGCCCTTTATGA CACTTGGAATAAGTATTTTGTACCGCAAGCCCAATGGTACAAACCCAGGCGTCTTCTCCT TCCTGAATCCTCTCTCCCCTGATATCTGGATGTATATTCTGCTGGCTTACTTGGGTGTCA GTTGTGTGCTCTTTGTCATAGCCAGGTTTAGTCCTTATGAGTGGTATAATCCACACCCTT GCAACCCTGACTCAGACGTGGTGGAAAACAATTTTACCTTGCTAAATAGTTTCTGGTTTG GAGTTGGAGCTCTCATGCAGCAAGGTTCTGAGCTCATGCCCAAAGCACTGTCCACCAGGA TAGTGGGAGGCATTTGGTGGTTTTTCACACTTATCATCATTTCTTCGTATACTGCTAACT TAGCCGCCTTTCTGACAGTGGAACGCATGGAATCCCCTATTGACTCTGCTGATGATTTAG CTAAACAAACCAAGATAGAATATGGAGCAGTAGAGGATGGTGCAACCATGACTTTTTTCA AGAAATCAAAAATCTCCACGTATGACAAAATGTGGGCCTTTATGAGTAGCAGAAGGCAGT CAGTGCTGGTCAAAAGTAATGAAGAAGGAATCCAGCGAGTCCTCACCTCTGATTATGCTT TCCTAATGGAGTCAACAACCATCGAGTTTGTTACCCAGCGGAACTGTAACCTGACACAGA TTGGCGGCCTTATAGACTCTAAAGGTTATGGCGTTGGCACTCCCATGGGTTCTCCATATC GAGACAAAATTACCATAGCAATTCTTCAGCTGCAAGAGGAAGGCAAACTGCATATGATGA AGGAGAAATGGTGGAGGGGCAATGGTTGCCCAGAAGAGGAGAGCAAAGAGGCCAGTGCCC TGGGGGTTCAGAATATTGGTGGCATCTTCATTGTTCTGGCAGCCGGCTTGGTGCTTTCAG TTTTTGTGGCAGTGGGAGAATTTTTATACAAATCCAAAAAAAACGCTCAATTGGAAAAGG AATCTTCTATTTGGTTAGTGCCACCATACCATCCAGACACTGTTTAGT >OriGene 5' read for NM_175768 unedited
CGTCACAATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGGATTTCTC CCGGATGCTCTCCGACTAACATGGATGTCCCACCATTCCTTGCAGTGGAAGGTTGTTCCT TGGCGCAGTGAGTGAAGAACATGCAGCGATTGCTAATGGGTTTGGGAAGCGGAGACTCCT TCCTCTCTCTATGACCATGCCGTGATCGTGTCTGCGGTCACCACTCGACGCATCCTCATT TCTACCCGAACCCAGGAGCCGAACGCTAGATCGGGGAAGTGGGTGCCGTGCGTGTGGGCA CAGAAACACCATGAAGATTATTTTCCCGATTCTAAGTAATCCAGTCTTCAGGCGCACCGT TAAACTCCTGCTCTGTTTACTGTGGATTGGATATTCTCAAGGAACCACACATGTATTAAG ATTTGGTGGTATTTTTGAATATGTGGAATCTGGCCCAATGGGAGCTGAGGAACTTGCATT CAGATTTGCTGTGAACACAATTAACAGAAACAGAACATTGCTACCCAATACTACCCTTAC CTATGATACCCAGAAGATAAACCTTTATGATAGTTTTGAAGCATCCAAGAAAGCCTGTGA TCAGCTGTCTCTTGGGGTGGCTGCCATCTTNCGGCCTTCACACAGCTCATCAGCAAACGC AGTGCAGTCCATCTGCAATGCTCTGGGAGTTCCCCACATACAGACCCGCTGGAAGCACCA GGTGTCAGACAACAAAAGATCCTTCTATGTCAGTCTCTACCCAGACTTTTTTTCACTCAG CCGTGCCATTTTAGAACTGGTGCAGTTTTTTCAAGTGGAAAACCGTACGGTTGGGTATG >OriGene 3' read for NM_175768 unedited
NCCCTGGGTGATGGCACTTCCAGGNCCAGNAAAGCACTGGGGNAGGGTCACAGGATGCCA CCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGACTAAACAG TGTCTGGATGGTATGGTGGCACTAACCAAATAGAAGATTCCTTTTCCAATTGAGCGTTTT TTTTGGATTTGTATAAAAATTCTCCCACTGCCACAAAAACTGAAAGCACCAAGCCGGCTG CCAGAACAATGAAGATGCCACCAATATTCTGAACCCCCAGGGCACTGGCCTCTTTGCTCT CCTCTTCTGGGCAACCATTGCCCCTCCACCATTTCTCCTTCATCATATGCAGTTTGCCTT CCTCTTGCAGCTGAAGAATTGCTATGGTAATTTTGTCTCGATATGGAGAACCCATGGGAG TGCCAACGCCATAACCTTTAGAGTCTATAAGGCCGCCAATCTGTGTCAGGTTACAGTTCC GCTGGGTAACAAACTCGATGGTTGTTGACTCCATTAGGAAAGCATAATCAGAGGTGAGGA CTCGCTGGATTCCTTCTTCATTACTTTTGACCAGCACTGACTGCCTTCTGCTACTCATAA AGGCCCACATTTTGTCATACGTGGAGATTTTTGATTTCTTGAAAAAAGTCATGGTTGCAC CATCCTCTACTGCTCCATATTCTATCTTGGTTTGTTTAGCTAAATCATCAGCAGAGTCAA TAGGGGATTCCATGCGTTCCACTGTCAGAAAAGGCGCTAAGTTAGCAGTATACGAAGAAA TGATGATNAGTGTGAAAAACCACAAATGCCTCCNACTATNCTGNTGNACAGTGCTTTTGG CATGAGCTCAGAACCTTGCTGCATGAGAGCTCCCACTCCCAACCAGAACTATTTAGCAAG |
| Restriction Sites | Please inquire |
| ACCN | NM_175768 |
| Insert Size | 2900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_175768.1, NP_786944.1 |
| RefSeq Size | 3409 bp |
| RefSeq ORF | 2610 bp |
| Locus ID | 2898 |
| UniProt ID | Q13002 |
| Protein Families | Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) contains an additional exon in the 3' coding region, compared to transcript variant 1. The resulting isoform (2) is shorter and has a distinct C-terminus compared to isoform 1. RNA editing changes Ile567Val, Tyr571Cys and Gln621Arg. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223048 | GRIK2 (Myc-DDK-tagged)-Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 2 |
CNY 6368.00 |
|
| RC223048L3 | Lenti ORF clone of Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 2, Myc-DDK-tagged |
CNY 9030.00 |
|
| RC223048L4 | Lenti ORF clone of Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 2, mGFP tagged |
CNY 9030.00 |
|
| RG223048 | GRIK2 (tGFP-tagged) - Human glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 2 |
CNY 7890.00 |
