ZNF451 (NM_015555) Human Untagged Clone
CAT＃: SC310007
ZNF451 (untagged)-Human zinc finger protein 451 (ZNF451), transcript variant 2
CNY 19570.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | COASTER; dJ417I1.1 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_015555, the custom clone sequence may differ by one or more nucleotides
ATGGGAGACCCGGGGTCGGAGATAATAGAATCTGTCCCTCCAGCTGGCCCTGAGGCATCT GAGTCAACAACGGATGAAAATGAAGACGACATTCAGTTTGTCAGTGAAGGACCATTACGA CCTGTTCTTGAATACATTGATCTGGTCAGCAGTGATGATGAAGAGCCTAGCACCTCTTAT ACTGATGAGAATATTAAACGTAAAGACCATATTGATTATCAGAAGGATAAAGTTGCTTTA ACTCTGGCTCGTCTAGCCCGCCATGTTGAAGTGGAGAAACAGCAGAAAGAAGAGAAGAAT AGAGCATTCAGAGAAAAAATTGATTTTCAGCATGCTCATGGGTTACAAGAATTGGAATTT ATTCGAGGACATTCTGATACAGAAGCAGCAAGACTGTGTGTGGACCAGTGGCTAAAAATG CCAGGACTCAAAACAGGCACAATTAATTGTGGAACAAAAAGTTCATTCCGAAGAGGAGGC CACACGTGGGTGTCTGGGAAACCAATTTTATGTCCTATAATGCACTGTAACAAGGAGTTT GACAATGGGCACCTTCTCTTAGGACATTTGAAAAGGTTCGATCACTCTCCATGTGATCCA ACAATTACACTACATGGACCTTTCTTCAGCTCCTTTGCTTGTGTAGTATGTTATAAAAAA TTTGTTACTCAACAACAATATAGAGATCACCTTTTTGATAAGGAAGCCACAGATGATGGA CATAACAACAACCTTCTTCCTCAGATTATTCAGTGTTTTGCATGTCCAAATTGCTTCCTT CTTTTTAGCAGAAAGGAGGAGTGTTCAAAGCATATGTCTGGAAAGAATCATTTCCATCAG AGTTTCAAACTGGGTGATAACAAAGGAATTGCACATCCAATATCTTTCCCATCTTTTGCA AAGAAACTTTTGATCTCTCTGTGCAAAGATGTTCCCTTTCAAGTTAAGTGTGTGGCCTGC CACAAGACACTGCGTTCCCACATGGAGCTCACTGCCCATTTCAGAGTTCATTGTCGAAAT GCTGGACCTGTAGCTGTAGCTGAGAAGAGCATTACCCAGGTTGCAGAGAAATTCATATTA AGAGGTTATTGTCCAGATTGCAATCAAGTCTTTGTGGATGAAACCAGCACCCAAAATCAT AAGCAGAATTCAGGACACAAAGTCCGAGTCATTAACTCAGTGGAAGAATCAGTCTTACTC TATTGCCACAGCAGCGAAGGGAACAAGGATCCTTCTTCTGACTTGCATTTATTGTTGGAT CAATCAAAATTTTCATCACTTAAAAGAACCATGTCTATTAAAGAATCTAGCTCACTGGAG TGCATTGCCATTCCAAAAAAGAAGATGAATTTAAAAGATAAAAGCCATGAAGGTGTTGCT TGTGTCCAGAAAGAAAAATCAGTAGTTAAAACCTGGTTCTGTGAATGCAATCAGCGATTC CCAAGTGAAGATGCAGTAGAAAAGCATGTTTTCTCAGCAAACACAATGGGTTATAAATGT GTGGTCTGTGGAAAGGTATGTGATGATTCAGGGGTCATTCGTTTACACATGAGCCGGATT CACGGAGGGGCACATTTAAATAACTTTCTTTTCTGGTGTCGGACATGCAAAAAGGAGTTA ACAAGGAAAGATACTATCATGGCACATGTGACTGAATTTCATAATGGACACAGATATTTT TATGAGATGGATGAGGTAGAAGGTGAAACTTTGCCATCATCCTCTACAACATTGGATAAT TTGACTGCTAACAAGCCTTCATCAGCTATTACTGTTATTGATCATTCCCCGGCAAATAGT TCTCCGAGGGGTAAATGGCAATGCCGGATTTGTGAAGATATGTTTGATTCCCAGGAATAT GTAAAACAGCACTGCATGTCTTTGGCAAGCCACAAGTTTCATAGATACAGCTGTGCTCAC TGCAGAAAGCCTTTTCATAAGATAGAAACATTGTACCGACATTGCCAAGATGAGCATGAC AATGAGATAAAGATTAAATACTTCTGTGGGCTTTGTGATCTTATCTTTAATGTGGAAGAA GCATTTCTGAGTCATTATGAGGAGCACCACAGCATAGATTATGTATTTGTGTCAGAAAAA ACTGAAACTTCAATTAAAACCGAAGATGATTTTCCAGTAATAGAGACCAGTAACCAGTTA ACTTGTGGTTGCCGTGAGAGTTACATCTGTAAAGTCAACAGAAAAGAAGATTATAGCAGA TGTCTCCAAATCATGCTGGATAAAGGAAAACTGTGGTTTCGCTGCAGTTTATGTTCGGCA ACAGCACAGAATTTAACCGACATGAACACTCATATCCATCAAGTGCACAAAGAAAAGAGT GATGAGGAGGAGCAGCAGTATGTAATCAAGTGTGGCACCTGCACCAAAGCATTTCATGAT CCTGAGAGTGCACAGCAGCATTTCCATAGAAAACATTGCTTCTTACAGAAACCCAGTGTG GCTCATTTTGGATCTGAAAAATCAAACCTGTACAAGTTTACTGCTAGTGCCTCACATACA GAGAGAAAACTGAAACAGGCAATAAACTATTCAAAAAGTTTAGACATGGAGAAAGGAGTT GAGAATGACCTAAGCTATCAGAATATAGGAGGAAACACCAATTGGAAGCCTCCGCTCAAC TGTAAGATTTATAACTACCTGAACAGGATTGGATGCTTCTTCCTTCATCCTCGCTGTAGT AAAAGAAAAGATGCTGCTGATTTTGCCATATGTATGCATGCTGGCCGTCTAGATGAACAA CTACCCAAGCAAATTCCTTTCACCATCCTCTCAGGAGATCAAGGTTTTCTGGAGCTAGAG AATCAATTTAAGAAGACTCAGAGGCCAGCTCATATACTAAACCCTCACCACTTAGAGGGA GATATGATGTGTGCCTTGTTAAATAGCATATCTGATACCACCAAAGAATGTGACAGTGAT GATAACATGGGTGCCAAAAATACTTCAATAGGAGAAGAATTTATATCCACAGAAGATGTG GAATTAGAAGAAGCTATTAGAAGAAGTCTTGAGGAAATGTAA |
| Restriction Sites | Please inquire |
| ACCN | NM_015555 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_015555.2, NP_056370.2 |
| RefSeq Size | 5097 bp |
| RefSeq ORF | 3042 bp |
| Locus ID | 26036 |
| UniProt ID | Q9Y4E5 |
| Domains | zf-C2H2 |
| Protein Families | Transcription Factors |
| Gene Summary | E3 SUMO-protein ligase; has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation (By similarity). Has no activity with SUMO1 (PubMed:26524493). Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11' (PubMed:26524493). Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9' (PubMed:24324267). Plays a role in regulating the transcription of AR targets (PubMed:18656483).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1. Isoform 2 is shorter, compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224347 | ZNF451 (Myc-DDK-tagged)-Human zinc finger protein 451 (ZNF451), transcript variant 2 |
CNY 10070.00 |
|
| RC224347L3 | Lenti-ORF clone of ZNF451 (Myc-DDK-tagged)-Human zinc finger protein 451 (ZNF451), transcript variant 2 |
CNY 11970.00 |
|
| RC224347L4 | Lenti-ORF clone of ZNF451 (mGFP-tagged)-Human zinc finger protein 451 (ZNF451), transcript variant 2 |
CNY 11970.00 |
|
| RG224347 | ZNF451 (tGFP-tagged) - Human zinc finger protein 451 (ZNF451), transcript variant 2 |
CNY 11120.00 |
