ARHGAP11A (NM_199357) Human Untagged Clone
CAT＃: SC307955
ARHGAP11A (untagged)-Human Rho GTPase activating protein 11A (ARHGAP11A), transcript variant 2
CNY 7980.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GAP (1-12) |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC307955 representing NM_199357.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTA CCGAGGAGATCTGCCGCCGCGATCGCCGGCGCGCCC ATGTGGGATCAGAGGCTGGTGAGGTTGGCCCTGTTGCAGCATCTGCGGGCCTTCTATGGTATTAAGGTG AAGGGTGTCCGTGGGCAGTGCGATCGCAGGAGACATGAAACAGCAGCCACGGAAATAGGGGGTAAAATA TTTGGAGTACCTTTTAATGCACTGCCCCATTCTGCTGTACCAGAATATGGACACATTCCAAGCTTTCTT GTCGATGCTTGCACATCTTTAGAAGACCATATTCATACCGAAGGGCTTTTTCGGAAATCAGGATCTGTG ATTCGCCTAAAAGCACTAAAGAATAAAGTGGATCATGGTGAAGGTTGCCTATCTTCTGCACCTCCTTGT GATATTGCGGGACTTCTTAAGCAGTTTTTTAGGGAACTGCCAGAGCCCATTCTCCCAGCTGATTTGCAT GAAGCACTTTTGAAAGCTCAACAGTTAGGCACAGAGGAAAAGAATAAAGCTACACTGTTGCTCTCCTGT CTTCTGGCTGACCACACAGTTCATGTATTAAGATACTTCTTTAACTTTCTCAGGAATGTTTCTCTTAGA TCCAGTGAGAATAAGATGGACAGCAGCAATCTTGCAGTAATATTTGCACCGAATCTTCTTCAGACAAGT GAAGGACATGAAAAGATGTCTTCTAACACAGAAAAGAAGCTACGATTACAGGCTGCAGTAGTACAGACT CTTATCGATTATGCATCAGATATTGGGCGTGTACCAGATTTTATCCTGGAAAAGATACCAGCCATGTTG GGTATTGATGGTCTCTGTGCTACTCCATCACTGGAAGGCTTTGAAGAAGGTGAATATGAAACTCCTGGT GAATATAAGAGAAAGAGAAGACAAAGTGTAGGAGATTTTGTTAGTGGAGCACTAAATAAATTTAAACCT AACAGAACACCTTCTATTACACCTCAAGAAGAAAGAATTGCCCAGCTATCTGAATCACCAGTGATTCTT ACACCAAATGCTAAGCGTACATTGCCAGTAGATTCTTCTCATGGTTTCTCAAGTAAGAAAAGGAAGTCC ATCAAGCACAATTTTAACTTTGAGCTGTTGCCAAGTAATCTCTTCAATAGCAGTTCTACACCGGTATCA GTTCACATCGATACAAGCTCAGAAGGGTCATCTCAGAGTTCACTCTCTCCTGTACTCATTGGTGGAAAC CATTTGATCACTGCAGGTGTGCCAAGGCGAAGTAAAAGAATTGCAGGCAAAAAAGTTTGCAGAGTGGAA TCAGGAAAAGCAGGCTGCTTTTCTCCTAAAATCAGCCATAAAGAAAAGGTTCGAAGATCTCTGCGTTTG AAATTCAATCTAGGGAAAAATGGCAGAGAAGTAAATGGATGTTCTGGTGTCAATAGATATGAAAGTGTT GGTTGGCGACTTGCAAATCAACAAAGTTTAAAAAATCGAATTGAATCTGTAAAAACAGGTTTGCTTTTT AGCCCAGATGTTGATGAAAAGTTACCAAAGAAAGGTACATTTACATACTACTGTTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | AscI-MluI |
| ACCN | NM_199357 |
| Insert Size | 1506 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_199357.1 |
| RefSeq Size | 2486 bp |
| RefSeq ORF | 1506 bp |
| Locus ID | 9824 |
| UniProt ID | Q6P4F7 |
| MW | 55.5 kDa |
| Gene Summary | This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein. [provided by RefSeq, Feb 2019] Transcript Variant: This variant (2) lacks a coding exon and its 3' terminal exon extends past a splice site used in variant 1, resulting in a distinct 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) has a distinct C-terminus and is shorter than isoform 1. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221029 | ARHGAP11A (Myc-DDK-tagged)-Human Rho GTPase activating protein 11A (ARHGAP11A), transcript variant 2 |
CNY 3728.00 |
|
| RC221029L3 | Lenti-ORF clone of ARHGAP11A (Myc-DDK-tagged)-Human Rho GTPase activating protein 11A (ARHGAP11A), transcript variant 2 |
CNY 6270.00 |
|
| RC221029L4 | Lenti-ORF clone of ARHGAP11A (mGFP-tagged)-Human Rho GTPase activating protein 11A (ARHGAP11A), transcript variant 2 |
CNY 6270.00 |
|
| RG221029 | ARHGAP11A (tGFP-tagged) - Human Rho GTPase activating protein 11A (ARHGAP11A), transcript variant 2 |
CNY 4850.00 |
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