RP1L1 (NM_178857) Human Untagged Clone
CAT＃: SC307234
RP1L1 (untagged)-Human retinitis pigmentosa 1-like 1 (RP1L1)
CNY 16376.00
货期*
现货
规格
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DCDC4B; OCMD; RP88 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC307234 sequence for NM_178857 edited (data generated by NextGen Sequencing)
ATGAACAGCACCCCCAGGAATGCCCAGGCCCCGAGCCACCGTGAGTGCTTCCTGCCCTCT GTGGCTCGCACCCCCTCGGTCACCAAGGTCACGCCAGCCAAGAAGATCACCTTCCTCAAG CGAGGGGATCCACGGTTTGCTGGGGTCCGCCTGGCCGTTCACCAGCGCGCCTTTAAGACC TTCAGCGCCCTCATGGACGAGCTCTCCCAGCGCGTGCCTCTCTCCTTTGGGGTGCGCTCT GTCACCACACCCCGGGGCCTGCATAGCCTCAGCGCCCTGGAGCAGCTGGAAGATGGAGGC TGCTACCTCTGCTCTGATAAGAAGCCCCCCAAGACCCCCAGTGGACCAGGCCGGCCACAG GAGAGAAACCCCACTGCTCAGCAGTTGCGGGATGTCGAAGGCCAGCGTGAAGCCCCAGGC ACCTCCTCCTCCCGGAAGAGTCTTAAAACCCCCCGGAGGATACTGCTGATTAAGAACATG GACCCTCGCCTCCAGCAGACAGTGGTTCTCAGTCACAGGAATACTAGGAACCTGGCCGCC TTTCTCGGCAAAGCCTCAGATCTCCTGCGCTTTCCTGTGAAGCAGTTGTACACGACCAGC GGGAAAAAGGTGGACTCGCTGCAGGCCCTGCTGCACAGCCCCTCTGTGCTGGTGTGTGCC GGGCATGAGGCCTTCAGAACCCCAGCCATGAAAAATGCCAGGAGAAGCGAGGCTGAAACT TTATCTGGGCTGACTTCAAGAAACAAAAACGGGAGCTGGGGGCCAAAGACCAAGCCGAGT GTGATCCATTCGCGGTCTCCGCCAGGCAGCACGCCACGGCTGCCAGAAAGGCCTGGTCCT AGCAACCCCCCGGTGGGCCCTGCTCCTGGCAGGCACCCTCAGGACACGCCAGCTCAGTCG GGCCCGCTGGTGGCTGGCGATGACATGAAGAAGAAGGTCCGCATGAATGAGGACGGCAGC CTGTCCGTGGAGATGAAAGTCCGCTTCCACCTGGTCGGCGAGGACACGCTCCTATGGTCC CGGAGGATGGGCAGGGCCAGCGCCCTCACGGCAGCCAGTGGGGAAGACCCCGTTCTGGGG GAGGTAGACCCCCTCTGCTGTGTGTGGGAGGGCTACCCTTGGGGCTTCTCAGAGCCTGGG GTGTGGGGACCCCGGCCCTGCAGGGTGGGATGCAGGGAAGTCTTTGGCCGAGGCGGGCAG CCAGGGCCCAAGTATGAAATCTGGACGAATCCCCTGCATGCCTCCCAGGGAGAGAGAGTG GCAGCTCGGAAGAGGTGGGGACTGGCCCAGCACGTCCGCTGCAGTGGCCTGTGGGGCCAC GGGACTGCCGGGAGGGAGAGATGCAGCCAGGACAGTGCCAGCCCAGCCTCCAGCACCGGC CTCCCCGAGGGCTCGGAGCCAGAGTCCTCCTGCTGCCCCAGGACCCCGGAGGACGGGGTG GACAGTGCCAGCCCCTCTGCCCAGATAGGGGCTGAGCGGAAAGCTGGAGGGAGCCTGGGT GAGGACCCCGGCCTATGCATAGATGGAGCAGGGCTGGGCGGCCCAGAGCAAGGCGGCCGC CTGACACCGAGGGCCCGGAGTGAGGAGGGGGCTTCTTCGGACTCGTCAGCCAGCACCGGC TCTCATGAGGGATCCAGCGAATGGGGTGGGCGGCCCCAGGGCTGTCCAGGCAAGGCAAGG GCCGAGACCTCTCAGCAGGAGGCCAGCGAGGGAGGCGACCCCGCTTCTCCAGCCCTGAGT CTTTCATCTTTAAGGAGTGACGACCTGCAGGCAGAGACGCAAGGACAGGGTACCGAGCAG GCCACGGGAGCGGCTGTGACAAGGGAGCCTCTGGTTCTGGGCCTTTCCTGCTCCTGGGAC TCGGAAGGAGCCTCTTCCACCCCTTCCACCTGCACTTCATCCCAGCAGGGGCAGAGAAGG CACAGAAGCCGGGCCAGTGCAATGTCCTCACCCAGCAGCCCTGGCCTTGGCCGAGTGGCC CCGAGAGGCCATCCCAGGCATTCTCACTACCGCAAGGACACCCACAGCCCACTGGACTCC TCTGTAACCAAGCAAGTGCCGAGGCCTCCTGAGCGGCGAAGGGCCTGCCAGGATGGCTCA GTGCCACGATATTCTGGAAGCTCATCGAGCACCAGGACACAGGCCTCTGGGAACCTGAGA CCTCCCTCCTCGGGCTCTCTTCCTTCCCAGGACCTTCTGGGAACCAGCAGTGCCACTGTC ACCCCTGCAGTCCACTCGGATTTTGTTTCTGGAGTCTCCCCGCACAATGCTCCCTCTGCC GGGTGGGCAGGGGACGCGGGGTCCAGGACATGCTCGCCGGCCCCCATACCTCCCCACACA TCCGACTCCTGCTCAAAATCTGGGGCTGCCAGCCTGGGGGAAGAGGCCAGGGACACGCCT CAGCCCTCCTCACCCTTGGTTCTGCAGGTTGGACGGCCTGAGCAAGGGGCGGTGGGCCCC CACCGAAGCCACTGCTGCTCACAGCCTGGGACGCAGCCGGCCCAAGAGGCCCAGCGGGGA CCCTCCCCTGAGGCTAGCTGGCTGTGTGGCAGGTACTGTCCCACCCCGCCCAGGGGGTGG CCCTGCCCCCAGAGGCGCTCTTCCAGCTGTGGGAGCACCGGCAGCAGCCACCAAAGCACT GCCCGGGGGCCAGGTGGGAGCCCGCAGGAGGGGACACGCCAGCCAGGCCCCACGCCGTCC CCAGGCCCCAATTCAGGGGCATCAAGGAGAAGCAGTGCCAGCCAGGGTGCGGGGTCTCGG GGGCTGTCCGAGGAGAAGACCTTGAGGAGTGGGGGAGGCCCCCAGGGGCAGGAGGAGGCC AGTGGTGTGTCACCCAGCTCTCTGCCCCGCTCGTCTCCAGAGGCTGTGGTCCGCGAATGG CTGGACAACATTCCAGAAGAGCCCATACTCATGACATATGAGTTGGCGGACGAGACCACA GGTGCAGCTGGGGGTGGCCTGAGAGGCCCCGAGGTGGACCCTGGGGATGACCATTCTCTG GAAGGCCTGGGGGAGCCAGCTCAGGCGGGACAGCAGTCCCTGGAAGGGGACCCCGGCCAG GACCCAGAGCCAGAGGGAGCCCTCCTGGGGAGTAGTGACACTGGTCCCCAATCAGGAGAG GGTGTCCCCCAAGGGGCAGCTCCAGAGGGAGTTTCCGAGGCCCCTGCAGAGGCCGGAGCA GACAGAGAGGCCCCAGCAGGCTGCAGGGTGAGCCTGCGGGCACTTCCTGGCCGGGTGTCT GCCTCCACGCAGATCATGAGGGCGCTGATGGGCTCCAAGCAGGGCCGGCCCAGCAGCGTG CCCGAAGTGTCTAGGCCCATGGCCAGGAGGCTCAGCTGCTCAGCCGGGGCCCTCATTACT TGTCTGGCCAGTCTGCAGTTATTTGAGGAAGACCTTGGGTCTCCTGCCAGCAAAGTGAGG TTCAAAGACTCCCCTTGGTACCAGGAGCTGCTCAGCATCTCGAAGGACCTGTGGCCAGGA TGTGACGTTGGGGAAGACCAGCTGGACTCAGGCCTCTGGGAGCTCACATGGAGCCAGGCT CTGCCAGACCTTGGGTCCCATGCCATGACGGAGAACTTCACGCCCACATCCTCCTCTGGT GTGGACATCAGCAGCGGCTCTGGAGGCTCAGGGGAGAGTAGCGTACCCTGTGCCATGGAC GGCACCCTGGTGACACAGGGGACAGAGCTGCCCCTGAAAACCTCCAACCAGAGGCCTGAT TCAAGAACTTATGAGAGCCCAGGGGATCTGGAAAACCAACAGCAGTGTTGTTTCCCAACC TTCTTGAACGCCCGAGCCTGCGCTTGTGCCACCAATGAGGATGAAGCAGAAAGAGACAGT GAGGAGCAGAGGGCGAGCTCGAACCTGGAGCAGTTAGCTGAAAACACAGTGCAAGAAGAG GTGCAATTAGAGGAAACTAAAGAAGGAACAGAAGGAGAAGGGCTGCAAGAAGAGGCGGTG CAGTTAGAGGAAACTAAAACAGAAGAAGGGCTGCAAGAAGAGGGGGTGCAGTTAGAGGAA ACTAAAGAAACAGAAGGAGAAGGACAGCAAGAAGAAGAGGCGCAGTTAGAGGAAATTGAA GAAACAGGAGGAGAAGGGCTGCAAGAAGAGGGGGTGCAGTTAGAGGAAGTTAAAGAAGGG CCAGAAGGAGGACTGCAAGGAGAGGCTCTTGAAGAGGGTCTCAAAGAGGAAGGACTTCCA GAAGAAGGAAGCGTCCACGGGCAGGAATTGTCAGAGGCCAGCTCTCCGGATGGGAAAGGC TCCCAGGAAGATGACCCAGTCCAGGAGGAGGAAGCAGGAAGAGCCTCTGCCTCTGCAGAG CCGTGCCCCGCAGAGGGCACAGAGGAACCCACAGAGCCCCCTAGTCATCTCAGCGAGACG GACCCAAGTGCCAGCGAGAGTCAGAGTGGCTCCCAGCTTGAGCCTGGTTTGGAAAAGCCG CCCGGAGCCACCATGATGGGCCAAGAGCACACGCAGGCCCAACCCACCCAGGGGGCTGCA GAGAGGAGCTCTTCGGTGGCCTGCAGCGCGGCTCTGGACTGCGACCCCATCTGGGTGTCC GTGTTACTGAAGAAGACGGAGAAGGCCTTCCTGGCCCACCTTGCCAGTGCGGTGGCTGAG CTCCGAGCACGCTGGGGCCTGCAGGACAATGATCTGCTGGACCAGATGGCGGCCGAGCTG CAGCAGGACGTGGCCCAACGCCTCCAGGACAGCACCAAGAGAGAGCTCCAGAAGCTCCAG GGCCGGGCGGGTAGGATGGTGCTGGAGCCTCCAAGGGAGGCCCTCACCGGGGAGCTGCTC CTGCAGACCCAGCAGCGCAGACACCGTCTCCGGGGCCTGCGAAACCTCTCGGCCTTCTCT GAGCGGACCCTGGGCCTGGGGCCCCTCTCCTTCACCCTGGAGGACGAGCCAGCCCTCAGC ACAGCCCTGGGGAGCCAGCTGGGCGAGGAGGCGGAGGGGGAGGAGTTCTGTCCCTGCGAG GCCTGCGTGAGGAAGAAAGTGAGCCCTATGTCCCCCAAGGCCACAATGGGGGCAACCAGA GGTCCCATCAAAGAGGCCTTTGACCTGCAGCAGATTCTGCAGAGGAAGAGGGGAGAACAC ACTGATGGGGAGGCAGCAGAGGTGGTCCCTGGCAAGACCCACACGGACCCCACGAGCACT AGGACTGTCCAGGGAGCTGAGGGAGGGCTGGGGCCGGGGCTGAGCCAGGGGCCTGGAGTG GACGAGGGTGAGGATGGCGAGGGGAGCCAGAGACTCAACAGAGACAAAGATCCCAAACTC GGGGAGGCAGAGGGAGATGCAATGGCTCAGGAGAGAGAAGGGAAAACCCACAACAGTGAA ACCAGTGCGGGCAGTGAGTTGGGGGAAGCTGAGCAGGAGGGAGAGGGCATAAGTGAAAGG GGAGAAACTGGGGGTCAAGGCTCTGGGCATGAGGACAACTTGCAGGGTGAAGCTGCGGCA GGAGGTGACCAAGATCCAGGACAGAGTGATGGGGCCGAAGGCATAGAGGCCCCGGAGGCT GAAGGGGAGGCCCAGCCAGAGTCAGAAGGTGTAGAGGCCCCAGAGGCAGAAGGGGATGCC CAGGAGGCTGAAGGGGAGGCCCAGCCAGAGTCAGAAGATGTAGAGGCCCCAGAGGCAGAA GGAGAGGCCCAGCCAGAGTCAGAAGATGTAGAGACCCCAGAGGCAGAATGGGAGGTCCAG CCAGAGTCAGAAGGTGCAGAAGCCCCGGAGGCAGAAAAGGAGGCCCAGCCAGAGACAGAA AGTGTAGAGGCCCTGGAGACTGAAGGGGAGGACGAGCCAGAGTCAGAAGGTGCAGAGGCC CAAGAGGCAGAAGAGGAGGCCCAGGAGGCAGAAGGGCAGGCCCAGCCAGAGTCAGAAGTT ATAGAGTCCCAGGAGGCAGAAGAGGAAGCCCAGCCAGAGTCAGAAGATGTAGAGGCCCTG GAGGTTGAAGTGGAGACCCAGGAGGCAGAAGGGGAGGCCCAGCCAGAGTCAGAAGATGTA GAGGCCCCAGAGGCTGAAGGGGAGATGCAAGAGGCAGAAGAGGAGGCCCAGCCAGAGTCA GACGGTGTAGAGGCCCAGCCAAAGTCAGAAGGTGAAGAGGCCCAGGAGGTTGAAGGGGAG ACCCAGAAGACAGAAGGGGATGCCCAGCCAGAGTCAGACGGTGTAGAGGCCCCGGAGGCA GAAGAGGAGGCACAGGAGGCTGAAGGGGAGGTCCAGGAGGCAGAAGGGGAGGCCCACCCA GAGTCAGAAGATGTAGATGCCCAGGAGGCAGAAGGGGAGGCCCAGCCAGAATCAGAAGGT GTAGAGGCCCCAGAGGCAGAAGGGGAGGCCCAGAAGGCAGAAGGTATAGAGGCCCCAGAG ACTGAAGGGGAGGCCCAGCCAGAGTCAGAAGGTATAGAGGCCCCAGAGGCTGAAGGGGAG GCCCAGCCTGAGTCAGAAGGTGTAGAGGCCCAGGATGCAGAAGGGGAGGCCCAGCCAGAG TCAGAAGGTATAGAGGCCCAGGAGGCTGAAGAGGAGGCCCAACCAGAGTTAGAAGGTGTA GAGGCCCCAGAGGCAGAAGGGGAGGCCCAGCCAGAGTCAGAAGGTATAGAGGCCCCAGAG GCAGAAGGGGAGGCCCAACCAGAGTTAGAAGGTGTAGAGGCCCCGGAGGCTGAAGAGGAG GCCCAGCCAGAGCCAGAAGGCGTAGAGACCCCGGAGGCTGAAGGGGAGGCCCAGCCAGAG TCGGAAGGAGAAACTCAAGGTGAGAAAAAGGGGAGCCCTCAGGTCAGTCTAGGAGATGGC CAATCTGAGGAGGCTTCTGAAAGCAGCAGCCCAGTCCCTGAGGACAGGCCCACTCCACCC CCTTCCCCAGGTAGAGACACTCCCCACCAAAGGCCAGGCTCCCAAACAGGCCCTTCCTCC TCCAGAGCATCCTCTTGGGGCAACTGCTGGCAGAAAGACTCAGAAAATGACCATGTACTT GGAGACACAAGGAGCCCTGATGCCAAGTCCACGGGGACCCCTCATGCAGAGAGGAAGGCC ACCAGGATGTACCCAGAAAGTTCTACTTCTGAGCAAGAAGAGGCCCCTTTGGGCTCAAGG ACTCCAGAGCAGGGGGCCAGTGAAGGTTATGACCTACAAGAGGACCAGGCACTCGGAAGT CTCGCCCCCACTGAGGCAGTGGGCAGGGCAGACGGCTTTGGCCAAGATGACTTAGATTTC TAG Clone variation with respect to NM_178857.5 1791 c=>t;2268 c=>t;2578 c=>t;3436 c=>t;4401 g=>t;5126 c=>t;5837 c=>a;5860 a=>g;6723 a=>g;6853 g=>a |
| Restriction Sites | Please inquire |
| ACCN | NM_178857 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_178857.4, NP_849188.3 |
| RefSeq Size | 8233 bp |
| RefSeq ORF | 7443 bp |
| Locus ID | 94137 |
| UniProt ID | Q8IWN7 |
| Gene Summary | This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, and two C-terminal large repetitive regions, both of which contain a high percentage of glutamine and glutamic acid residues. This protein is a retinal-specific protein. Its exact length varies among individuals due to the presence of a 16aa repeat in the first C-terminal repetitive region. The 16aa repeat is encoded by the highly polymorphic 48-bp repeat, and 1-6 copies of the 16aa repeat have been identified in normal individuals. The current reference sequence shown here has a single copy of the 16aa repeat. This protein and the RP1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Mutations in this gene cause occult macular dystrophy (OMD). [provided by RefSeq, Sep 2010] |
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