PPIL5 (LRR1) (NM_152329) Human Untagged Clone
CAT＃: SC306366
LRR1 (untagged)-Human leucine rich repeat protein 1 (LRR1), transcript variant 1
CNY 7220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 4-1BBLRR; LRR-1; PPIL5 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_152329, the custom clone sequence may differ by one or more nucleotides
ATGAAGCTACACTGTGAGGTGGAGGTGATCAGCCGGCACTTGCCCGCCTTGGGGCTTAGG AACCGGGGCAAGGGCGTCCGAGCCGTGTTGAGCCTCTGTCAGCAGACTTCCAGGAGTCAG CCGCCGGTCCGAGCCTTCCTGCTCATCTCCACCCTGAAGGACAAGCGCGGGACCCGCTAT GAGCTAAGGGAGAACATTGAGCAATTCTTCACCAAATTTGTAGATGAGGGGAAAGCCACT GTTCGGTTAAAGGAGCCTCCTGTGGATATCTGTCTAAGTAAGGCCATTTCCAGCAGTTTA AAAGGTTTCCTTTCAGCTATGAGACTGGCTCATAGAGGCTGTAATGTTGATACACCAGTT TCAACGCTCACACCAGTGAAGACTTCAGAATTTGAAAACTTTAAAACTAAAATGGTTATC ACATCCAAAAAAGACTATCCTCTAAGTAAGAATTTTCCATATTCCTTGGAACATCTTCAG ACTTCTTACTGTGGGCTTGTCCGAGTTGATATGCGTATGCTTTGCTTAAAAAGCCTTAGG AAATTAGACTTGAGTCACAACCATATAAAAAAGCTTCCAGCTACAATTGGAGACCTCATA CACCTTCAAGAACTTAACCTGAATGACAATCACTTGGAGTCATTTAGTGTAGCCTTGTGT CATTCTACACTCCAGAAGTCACTTCGGAGTTTGGACCTCAGCAAGAACAAAATCAAGGCA CTCCCTGTGCAGTTTTGCCAGCTCCAGGAACTTAAGAATTTAAAACTTGACGATAATGAA TTGATTCAATTTCCTTGCAAGATAGGACAACTAATAAACCTTCGCTTTTTGTCAGCAGCT CGAAATAAGCTTCCATTTTTGCCTAGTGAATTTAGAAATTTATCCCTTGAATACTTGGAT CTTTTTGGAAATACTTTTGAACAACCAAAAGTCCTTCCAGTAATAAAGCTGCAAGCACCA TTAACTTTATTGGAATCTTCTGCACGAACCATATTACATAATAGGATTCCATATGGCTCT CATATCATTCCATTCCATCTCTGCCAAGATTTGGATACCGCAAAAATTTGTGTTTGTGGA AGATTCTGTCTGAACTCTTTCATTCAAGGAACTACTACCATGAATCTGCATTCTGTTGCC CACACTGTGGTCTTAGTAGATAATTTGGGTGGTACTGAAGCACCTATTATCTCTTATTTC TGTTCTCTAGGCTGTTATGTTAATTCCTCTGATATGTTAAAGTAA |
| Restriction Sites | Please inquire |
| ACCN | NM_152329 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_152329.3, NP_689542.2 |
| RefSeq Size | 1760 bp |
| RefSeq ORF | 1245 bp |
| Locus ID | 122769 |
| UniProt ID | Q96L50 |
| Protein Families | Druggable Genome |
| Gene Summary | The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011] Transcript Variant: This variant (1) encodes the longest isoform (1). Isoform 1 has also been named LRR-1a. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219944 | LRR1 (Myc-DDK-tagged)-Human leucine rich repeat protein 1 (LRR1), transcript variant 1 |
CNY 4024.00 |
|
| RC219944L3 | Lenti-ORF clone of LRR1 (Myc-DDK-tagged)-Human leucine rich repeat protein 1 (LRR1), transcript variant 1 |
CNY 5990.00 |
|
| RC219944L4 | Lenti-ORF clone of LRR1 (mGFP-tagged)-Human leucine rich repeat protein 1 (LRR1), transcript variant 1 |
CNY 5990.00 |
|
| RG219944 | LRR1 (tGFP-tagged) - Human leucine rich repeat protein 1 (LRR1), transcript variant 1 |
CNY 4470.00 |
