ADAMTS13 (NM_139026) Human Untagged Clone
CAT＃: SC306109
ADAMTS13 (untagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13), transcript variant 3
CNY 25750.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADAM-TS13; ADAMTS-13; C9orf8; vWF-CP; VWFCP |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_139026, the custom clone sequence may differ by one or more nucleotides
ATGCACCAGCGTCACCCCCGGGCAAGATGCCCTCCCCTCTGTGTGGCCGGAATCCTTGCC TGTGGCTTTCTCCTGGGCTGCTGGGGACCCTCCCATTTCCAGCAGAGTTGTCTTCAGGCT TTGGAGCCACAGGCCGTGTCTTCTTACTTGAGCCCTGGTGCTCCCTTAAAAGGCCGCCCT CCTTCCCCTGGCTTCCAGAGGCAGAGGCAGAGGCAGAGGCGGGCTGCAGGCGGCATCCTA CACCTGGAGCTGCTGGTGGCCGTGGGCCCCGATGTCTTCCAGGCTCACCAGGAGGACACA GAGCGCTATGTGCTCACCAACCTCAACATCGGGGCAGAACTGCTTCGGGACCCGTCCCTG GGGGCTCAGTTTCGGGTGCACCTGGTGAAGATGGTCATTCTGACAGAGCCTGAGGGTGCC CCAAATATCACAGCCAACCTCACCTCGTCCCTGCTGAGCGTCTGTGGGTGGAGCCAGACC ATCAACCCTGAGGACGACACGGATCCTGGCCATGCTGACCTGGTCCTCTATATCACTAGG TTTGACCTGGAGTTGCCTGATGGTAACCGGCAGGTGCGGGGCGTCACCCAGCTGGGCGGT GCCTGCTCCCCAACCTGGAGCTGCCTCATTACCGAGGACACTGGCTTCGACCTGGGAGTC ACCATTGCCCATGAGATTGGGCACAGCTTCGGCCTGGAGCACGACGGCGCGCCCGGCAGC GGCTGCGGCCCCAGCGGACACGTGATGGCTTCGGACGGCGCCGCGCCCCGCGCCGGCCTC GCCTGGTCCCCCTGCAGCCGCCGGCAGCTGCTGAGCCTGCTCAGCGCCAACGAGCAGTGC CGCGTGGCCTTCGGCCCCAAGGCTGTCGCCTGCACCTTCGCCAGGGAGCACCTGGATATG TGCCAGGCCCTCTCCTGCCACACAGACCCGCTGGACCAAAGCAGCTGCAGCCGCCTCCTC GTTCCTCTCCTGGATGGGACAGAATGTGGCGTGGAGAAGTGGTGCTCCAAGGGTCGCTGC CGCTCCCTGGTGGAGCTGACCCCCATAGCAGCAGTGCATGGGCGCTGGTCTAGCTGGGGT CCCCGAAGTCCTTGCTCCCGCTCCTGCGGAGGAGGTGTGGTCACCAGGAGGCGGCAGTGC AACAACCCCAGACCTGCCTTTGGGGGGCGTGCATGTGTTGGTGCTGACCTCCAGGCCGAG ATGTGCAACACTCAGGCCTGCGAGAAGACCCAGCTGGAGTTCATGTCGCAACAGTGCGCC AGGACCGACGGCCAGCCGCTGCGCTCCTCCCCTGGCGGCGCCTCCTTCTACCACTGGGGT GCTGCTGTACCACACAGCCAAGGGGATGCTCTGTGCAGACACATGTGCCGGGCCATTGGC GAGAGCTTCATCATGAAGCGTGGAGACAGCTTCCTCGATGGGACCCGGTGTATGCCAAGT GGCCCCCGGGAGGACGGGACCCTGAGCCTGTGTGTGTCGGGCAGCTGCAGGACATTTGGC TGTGATGGTAGGATGGACTCCCAGCAGGTATGGGACAGGTGCCAGGTGTGTGGTGGGGAC AACAGCACGTGCAGCCCACGGAAGGGCTCTTTCACAGCTGGCAGAGCGAGAGAATATGTC ACATTTCTGACAGTTACCCCCAACCTGACCAGTGTCTACATTGCCAACCACAGGCCTCTC TTCACACACTTGGCGGTGAGGATCGGAGGGCGCTATGTCGTGGCTGGGAAGATGAGCATC TCCCCTAACACCACCTACCCCTCCCTCCTGGAGGATGGTCGTGTCGAGTACAGAGTGGCC CTCACCGAGGACCGGCTGCCCCGCCTGGAGGAGATCCGCATCTGGGGACCCCTCCAGGAA GATGCTGACATCCAGGTTTACAGGCGGTATGGCGAGGAGTATGGCAACCTCACCCGCCCA GACATCACCTTCACCTACTTCCAGCCTAAGCCACGGCAGGCCTGGGTGTGGGCCGCTGTG CGTGGGCCCTGCTCGGTGAGCTGTGGGGCAGGGCTGCGCTGGGTAAACTACAGCTGCCTG GACCAGGCCAGGAAGGAGTTGGTGGAGACTGTCCAGTGCCAAGGGAGCCAGCAGCCACCA GCGTGGCCAGAGGCCTGCGTGCTCGAACCCTGCCCTCCCTACTGGGCGGTGGGAGACTTC GGCCCATGCAGCGCCTCCTGTGGGGGCGGCCTGCGGGAGCGGCCAGTGCGCTGCGTGGAG GCCCAGGGCAGCCTCCTGAAGACATTGCCCCCAGCCCGGTGCAGAGCAGGGGCCCAGCAG CCAGCTGTGGCGCTGGAAACCTGCAACCCCCAGCCCTGCCCTGCCAGGTGGGAGGTGTCA GAGCCCAGCTCATGCACATCAGCTGGTGGAGCAGGCCTGGCCTTGGAGAACGAGACCTGT GTGCCAGGGGCAGATGGCCTGGAGGCTCCAGTGACTGAGGGGCCTGGCTCCGTAGATGAG AAGCTGCCTGCCCCTGAGCCCTGTGTCGGGATGTCATGTCCTCCAGGCTGGGGCCATCTG GATGCCACCTCTGCAGGGGAGAAGGCTCCCTCCCCATGGGGCAGCATCAGGACGGGGGCT CAAGCTGCACACGTGTGGACCCCTGCGGCAGGGTCGTGCTCCGTCTCCTGCGGGCGAGGT CTGATGGAGCTGCGTTTCCTGTGCATGGACTCTGCCCTCAGGGTGCCTGTCCAGGAAGAG CTGTGTGGCCTGGCAAGCAAGCCTGGGAGCCGGCGGGAGGTCTGCCAGGCTGTCCCGTGC CCTGCTCGGTGGCAGTACAAGCTGGCGGCCTGCAGCGTGAGCTGTGGGAGAGGGGTCGTG CGGAGGATCCTGTATTGTGCCCGGGCCCATGGGGAGGACGATGGTGAGGAGATCCTGTTG GACACCCAGTGCCAGGGGCTGCCTCGCCCGGAACCCCAGGAGGCCTGCAGCCTGGAGCCC TGCCCACCTAGGTGGAAAGTCATGTCCCTTGGCCCATGTTCGGCCAGCTGTGGCCTTGGC ACTGCTAGACGCTCGGTGGCCTGTGTGCAGCTCGACCAAGGCCAGGACGTGGAGGTGGAC GAGGCGGCCTGTGCGGCGCTGGTGCGGCCCGAGGCCAGTGTCCCCTGTCTCATTGCCGAC TGCACCTACCGCTGGCATGTTGGCACCTGGATGGAGTGCTCTGTTTCCTGTGGGGATGGC ATCCAGCGCCGGCGTGACACCTGCCTCGGACCCCAGGCCCAGGCGCCTGTGCCAGCTGAT TTCTGCCAGCACTTGCCCAAGCCGGTGACTGTGCGTGGCTGCTGGGCTGGGCCCTGTGTG GGACAGGGTGCCTGTGGCAGGCAGCACCTTGAGCCAACAGGAACCATTGACATGCGAGGC CCAGGGCAGGCAGACTGTGCAGTGGCCATTGGGCGGCCCCTCGGGGAGGTGGTGACCCTC CGCGTCCTTGAGAGTTCTCTCAACTGCAGTGCGGGGGACATGTTGCTGCTTTGGGGCCGG CTCACCTGGAGGAAGATGTGCAGGAAGCTGTTGGACATGACTTTCAGCTCCAAGACCAAC ACGCTGGTGGTGAGGCAGCGCTGCGGGCGGCCAGGAGGTGGGGTGCTGCTGCGGTATGGG AGCCAGCTTGCTCCTGAAACCTTCTACAGAGAATGTGACATGCAGCTCTTTGGGCCCTGG GGTGAAATCGTGAGCCCCTCGCTGAGTCCAGCCACGAGTAATGCAGGGGGCTGCCGGCTC TTCATTAATGTGGCTCCGCACGCACGGATTGCCATCCATGCCCTGGCCACCAACATGGGC GCTGGGACCGAGGGAGCCAATGCCAGCTACATCTTGATCCGGGACACCCACAGCTTGAGG ACCACAGCGTTCCATGGGCAGCAGGTGCTCTACTGGGAGTCAGAGAGCAGCCAGGCTGAG ATGGAGTTCAGCGAGGGCTTCCTGAAGGCTCAGGCCAGCCTGCGGGGCCAGTACTGGACC CTCCAATCATGGGTACCGGAGATGCAGGACCCTCAGTCCTGGAAGGGAAAGGAAGGAACC TGA |
| Restriction Sites | Please inquire |
| ACCN | NM_139026 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_139026.2, NP_620595.1 |
| RefSeq Size | 4672 bp |
| RefSeq ORF | 4023 bp |
| Locus ID | 11093 |
| UniProt ID | Q76LX8 |
| Protein Families | Secreted Protein, Transmembrane |
| Gene Summary | This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Transcript Variant: This variant (3) uses alternate in-frame splice sites at two exons, compared to variant 1. The encoded isoform (3) is shorter than isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222049 | ADAMTS13 (Myc-DDK-tagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13), transcript variant 3 |
CNY 13400.00 |
|
| RC222049L3 | Lenti-ORF clone of ADAMTS13 (Myc-DDK-tagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13), transcript variant 3 |
CNY 15300.00 |
|
| RC222049L4 | Lenti-ORF clone of ADAMTS13 (mGFP-tagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13), transcript variant 3 |
CNY 15300.00 |
|
| RG222049 | ADAMTS13 (tGFP-tagged) - Human ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13), transcript variant 3 |
CNY 14730.00 |
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