RNF157 (NM_052916) Human Untagged Clone
CAT＃: SC305693
RNF157 (untagged)-Human ring finger protein 157 (RNF157)
CNY 13110.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC305693 representing NM_052916.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGGGGCCCTGACGAGCCGGCAGCACGCGGGCGTGGAGGAGGTGGACATCCCGTCTAATTCCGTGTAC CGCTACCCGCCCAAGTCCGGAAGCTATTTTGCCAGCCACTTCATTATGGGAGGAGAGAAGTTTGACTCA ACTCATCCTGAAGGTTACCTGTTTGGAGAGAACAGCGATCTGAACTTTCTGGGGAACAGACCAGTTGTG TTTCCTTACGCCGCCCCACCTCCCCAAGAACCCGTGAAGACTCTGAGAAGCCTGGTCAATATCCGAAAG GACACACTGAGGCTCGTCAAATGTGCTGAGGAAGTGAAGAGCCCTGGAGAAGAGGCCAGTAAAGCTAAA GTCCACTACAATGTTGAGTTCACCTTTGACACAGATGCTCGGGTAGCCATCACCATCTATTACCAGGCC ACGGAAGAGTTCCAGAATGGTATTGCCAGCTACATTCCCAAAGACAACAGCCTCCAGTCGGAGACTGTG CAGTACAAGCGAGGAGTGTGTCAGCAGTTCTGCCTGCCCTCCCACACCGTGGATCCCTCCGAGTGGGCC GAAGAGGAGCTTGGCTTTGATTTAGACCGAGAAGTTTACCCTCTAGTGGTACATGCCGTGGTGGATGAA GGAGACGAGTATTTTGGCCATTGCCATGTACTGCTGGGTACTTTTGAGAAGCACACAGATGGAACTTTC TGTGTCAAGCCCCTCAAACAGAAACAAGTAGTAGACGGGGTCAGCTACCTCCTTCAGGAGATCTATGGA ATTGAAAACAAGTACAACACACAAGATTCTAAGGTGGCTGAAGACGAAGTGAGTGATAACAGTGCCGAG TGTGTGGTGTGTCTCTCGGATGTCCGGGACACCTTGATTCTGCCCTGTCGCCACCTCTGCCTCTGTAAC ACCTGTGCAGACACGCTGCGCTACCAGGCCAACAACTGCCCCATCTGCCGACTGCCCTTCCGGGCACTG CTTCAGATCCGAGCCATGAGGAAAAAATTGGGCCCCTTGTCCCCAACCAGCTTTAACCCCATCATCTCA TCCCAGACATCTGACTCTGAAGAGCATCCATCCTCAGAGAATATTCCACCAGGCTATGAAGTAGTATCT CTTCTGGAGGCCCTCAACGGGCCCCTCACCCCGTCCCCAGCAGTTCCTCCACTTCACGTGCTTGGAGAT GGCCACCTCTCAGGAATGCTCCCTTCATATGGCAGTGATGGCCACCTGCCCCCCGTCAGGACGATCTCG CCTCTTGACCGCCTGTCTGACAGCAGCAGTCAGGGACTCAAACTCAAAAAGAGTCTCTCCAAATCCACT TCCCAAAACTCTTCCGTGCTGCATGAAGAGGAAGATGAGCATTCCTGCAGCGAGTCGGAGACACAGCTC TCTCAGAGACCGTCGGTTCAGCATCTCGGAGAGGAATGTGGTGTGACTCCAGAAAGTGAGAATCTCACC TTGTCGTCATCTGGAGCTATTGACCAGTCGTCTTGCACAGGGACGCCTCTGTCATCCACTATTTCCTCC CCAGAAGGCCCTGCCAGCAGCAGCTTGGCCCAGTCTGTCATGTCCATGGCATCCTCCCAGATCAGCACT GACACCGTCTCCTCCATGTCTGGCTCCTACATCGCCCCTGGCACTGAAGAGGAGGGAGAGGCTCTCTCT TCCCCCCAGCCTGCCAGCAGGGCCCCCTCAGAAGAAGGAGAGGGGCTGCCAGCGGAGTCTCCAGACAGC AACTTTGCTGGCCTCCCAGCTGGAGAGCAGGATGCAGAGGGAAATGATGTTATAGAGGAAGAGGATGGA TCACCCACGCAGGAAGGCCAGAGGACGTGCGCATTTCTAGGTATGGAGTGTGACAATAACAATGACTTT GACATCGCAAGCGTGAAAGCACTGGACAATAAGCTGTGCTCTGAGGTCTGCTTACCTGGTGCCTGGCAG GCTGATGACAATGCCGTCAGTCGGAATGCCCAGCGCCGGCGCTTGTCATCCAGCAGCCTGGAGGACTCT GAGACGAGGCCCTGTGTGTGGGGCCCTTTGGCTGTCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_052916 |
| Insert Size | 2040 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_052916.2 |
| RefSeq Size | 4915 bp |
| RefSeq ORF | 2040 bp |
| Locus ID | 114804 |
| UniProt ID | Q96PX1 |
| Protein Families | Druggable Genome |
| MW | 73.6 kDa |
| Gene Summary | E3 ubiquitin ligase that ubiquitinates APBB1 for its degradation by the proteasome and thus prevents apoptosis and promotes survival of neurons (PubMed:25342469). Has a dual role in neurons as it is also required for dendrite growth and maintenance for which its ligase activity is not critical (PubMed:25342469). May act as a scaffold molecule to regulate this process (PubMed:25342469). Acts as a downstream effector of the interconnected PI3K and MAPK signaling pathways and thus participates in the regulation of the cell cycle (PubMed:28655764).[UniProtKB/Swiss-Prot Function] |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220648 | RNF157 (Myc-DDK-tagged)-Human ring finger protein 157 (RNF157) |
CNY 4976.00 |
|
| RC220648L1 | Lenti ORF clone of Human ring finger protein 157 (RNF157), Myc-DDK-tagged |
CNY 7376.00 |
|
| RC220648L2 | Lenti ORF clone of Human ring finger protein 157 (RNF157), mGFP tagged |
CNY 7700.00 |
|
| RC220648L3 | Lenti ORF clone of Human ring finger protein 157 (RNF157), Myc-DDK-tagged |
CNY 7700.00 |
|
| RC220648L4 | Lenti ORF clone of Human ring finger protein 157 (RNF157), mGFP tagged |
CNY 7700.00 |
|
| RG220648 | RNF157 (tGFP-tagged) - Human ring finger protein 157 (RNF157) |
CNY 6370.00 |
