ABCD4 (NM_020325) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	ABC41; EST352188; MAHCJ; P70R; P79R; PMP69; PXMP1L
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF Sequence for NM_020325. The custom clone sequence may differ by one or more nucleotides ATGGCGGTCGCGGGGCCCGCGCCCGGAGCTGGCGCCAGGCCCAGGTTAGATCTGCAATTT CTCCAGCGGTTCCTGCAGATACTGAAGGTTTTGTTTCCTTCTTGGTCATCACAAAATGCC TTGATGTTCCTGACCCTTTTGTGCCTGACCCTACTGGAGCAATTTGTGATCTACCAGGTT GGCTTGATCCCCAGTCAGTACTATGGGGTCCTGGGAAACAAAGACTTGGAAGGGTTTAAG ACTCTGACATTCCTGGCTGTCATGCTCATTGTTCTGAACTCCACGCTGAAGAGCTTTGAT CAGTTCACCTGCAACCTGCTGTATGTGAGCTGGAGGAAGGACCTCACTGAGCACCTTCAC CGCCTCTACTTCCGGGGCCGTGCGTACTACACCCTCAACGTGCTGCGGGATGACATCGAT AACCCGGACCAGCGCATCAGCCAGGACGTGGAGCGATTCTGCCGGCAGCTCAGCAGCATG GCCAGCAAGCTCATCATCTCCCCGTTCACCCTCGTCTACTACACTTACCAGTGCTTCCAA AGCACAGGCTGGCTCGGGCCTGTGAGCATCTTCGGGTATTTCATCCTGGGGACCGTGGTG AACAAAACTTTGATGGGCCCCATTGTGATGAAGCTGGTGCATCAGGAGAAGCTGGAGGGA GATTTTAGGTTCAAGCACATGCAGATTCGGGTGAATGCGGAGCCTGCTGCTTTCTACAGA GCTGGGCATGTGGAGCACATGAGGACAGACCGCAGGCTGCAGAGACTCCTTCAGACCCAG AGGGAGCTGATGTCCAAGGAGCTCTGGCTGTACATCGGCATCAACACCTTTGACTATCTG GGCAGCATCCTGAGTTATGTTGTCATCGCAATCCCCATTTTCAGCGGGGTCTATGGAGAC CTGAGTCCCGCAGAGCTTAGCACCCTGGTCAGCAAGAATGCCTTTGTGTGCATCTACCTC ATCAGCTGCTTCACCCAGCTCATCGACCTGTCCACGACGCTCTCAGATGTGGCTGGCTAC ACGCACAGAATTGGGCAGCTTCGGGAGACGCTTCTGGACATGTCCCTGAAGTCACAGGAC TGCGAGATCCTGGGCGAGAGCGAGTGGGGCTTGGACACACCCCCAGGGTGGCCAGCGGCA GAGCCAGCAGACACAGCATTTCTCCTTGAGCGGGTCTCCATCTCTGCCCCCTCCTCTGAC AAACCCCTAATCAAGGATCTGAGCCTAAAGATCTCCGAGGGACAGAGCCTGCTCATCACA GGCAACACGGGCACTGGCAAGACCTCCTTGCTCCGGGTTCTAGGTGGCCTCTGGACGAGT ACACGGGGCTCAGTGCAGATGCTGACGGACTTTGGGCCCCATGGGGTGCTATTCCTGCCA CAAAAGCCATTCTTCACTGACGGGACCCTTCGGGAGCAGGTGATATATCCCCTGAAGGAG GTCTACCCCGACTCAGGTTCTGCCGATGATGAGAGGATCTTGAGGTTCTTGGAATTGGCA GGCCTGTCCAACTTGGTGGCAAGGACAGAGGGTCTGGACCAGCAGGTGGACTGGAACTGG TATGATGTTCTGTCCCCGGGGGAGATGCAACGGCTCTCCTTTGCCCGACTCTTCTACCTG CAGCCGAAGTACGCAGTGCTTGATGAAGCCACCAGTGCCCTGACAGAGGAAGTGGAGAGC GAGCTCTAT
Restriction Sites	Please inquire
ACCN	NM_020325
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_020325.1, NP_064730.1
RefSeq Size	3098 bp
RefSeq ORF	1779 bp
Locus ID	5826
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	ABC transporters
Gene Summary	The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants. [provided by RefSeq, Jul 2017] Transcript Variant: This variant (4) contains a 171 bp insertion as a result of intron 18 retention. Inclusion of this intron results a premature stop codon and omission of the 14 amino-acid C-terminus present in transcript variant 1.

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