gp340 (DMBT1) (NM_017579) Human Untagged Clone
CAT＃: SC304489
DMBT1 (untagged)-Human deleted in malignant brain tumors 1 (DMBT1), transcript variant 3
CNY 46270.00
货期*
详询
规格
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GP340; muclin; SAG; SALSA |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_017579, the custom clone sequence may differ by one or more nucleotides
ATGGGGATCTCCACAGTCATCCTTGAAATGTGTCTTTTATGGGGACAAGTTCTATCTACA GGTGGGTGGATCCCAAGGACTACAGACTACGCTTCACTGATTCCCTCGGAGGTGCCCTTG GATCCAACTGTAGCAGAAGGTTCTCCATTTCCCTCGGAGTCGACCCTGGAGTCAACTGTA GCAGAAGGTTCTCCGATTTCCTTGGAGTCAACCCTGGAGTCAACCGTAGCAGAAGGTTCT CTGATTCCCTCAGAGTCAACCCTGGAGTCAACTGTAGCAGAAGGATCTGATTCTGGTTTG GCCCTGAGGCTGGTGAATGGAGATGGCAGGTGTCAGGGCCGAGTGGAGATCCTATACCGA GGCTCCTGGGGCACCGTGTGTGATGACAGCTGGGACACCAATGATGCCAACGTGGTCTGT AGGCAGCTGGGTTGTGGCTGGGCCATGTCAGCTCCAGGAAATGCCTGGTTTGGCCAGGGC TCAGGACCCATTGCCCTGGATGATGTGCGCTGCTCAGGACACGAATCCTACCTGTGGAGC TGCCCCCACAATGGCTGGCTCTCCCATAACTGTGGCCATGGTGAAGATGCTGGTGTTATC TGCTCAGCTGCCCAGCCTCAGTCAACACTCAGGCCAGAAAGTTGGCCTGTCAGGATATCA CCACCTGTACCCACAGAAGGATCTGAATCCAGTTTGGCCCTGAGGCTGGTGAATGGAGGC GACAGGTGTCGAGGCCGAGTGGAGGTCCTATACCGAGGCTCCTGGGGCACCGTGTGTGAT GACTACTGGGACACCAATGATGCCAATGTGGTCTGCAGGCAGCTGGGCTGTGGCTGGGCC ATGTCAGCCCCAGGAAATGCCCAGTTTGGCCAGGGCTCAGGACCCATTGTCCTGGATGAT GTGCGCTGCTCAGGACATGAGTCCTACCTGTGGAGCTGCCCCCACAATGGCTGGCTCACC CACAACTGTGGCCATAGTGAAGACGCTGGTGTCATCTGCTCAGCTCCCCAGTCCCGGCCG ACACCCAGCCCAGATACTTGGCCGACCTCACATGCATCAACAGCAGGACCTGAATCCAGT TTGGCCCTGAGGCTGGTGAATGGAGGTGACAGGTGTCAGGGCCGAGTGGAGGTCCTATAC CGAGGCTCCTGGGGCACCGTGTGTGATGATAGCTGGGACACCAGTGACGCCAATGTGGTC TGCCGGCAGCTGGGCTGTGGCTGGGCCACGTCAGCCCCAGGAAATGCCCGGTTTGGCCAG GGTTCAGGACCCATTGTCCTGGATGACGTGCGCTGCTCAGGCTATGAGTCCTACCTGTGG AGCTGCCCCCACAATGGCTGGCTCTCCCATAACTGTCAGCACAGTGAAGACGCTGGTGTC ATCTGCTCAGACACGTTGCCGACCATCACCTTACCTGCATCGACAGTAGGATCTGAATCC AGTTTGGCCCTGAGGCTGGTGAATGGAGGTGACAGGTGTCAGGGCCGAGTGGAGGTCCTA TACCGAGGCTCCTGGGGCACCGTGTGTGATGACAGCTGGGACACCAATGATGCCAATGTG GTCTGCAGGCAGCTGGGCTGTGGCTGGGCCATGTTGGCCCCAGGAAATGCCCGGTTTGGT CAGGGCTCAGGACCCATTGTCCTGGATGACGTGCGCTGCTCAGGGAATGAGTCCTACTTG TGGAGCTGCCCCCACAATGGCTGGCTCTCCCATAACTGTGGCCATAGTGAAGACGCTGGT GTCATCTGCTCAGGACCTGAATCCAGTTTGGCCCTGAGGCTGGTGAATGGAGGTGACAGG TGTCAGGGCCGAGTGGAGGTCCTATACCGAGGCTCTTGGGGCACCGTGTGTGATGACAGC TGGGACACCAATGATGCCAATGTGGTCTGCAGGCAGCTGGGCTGTGGCTGGGCCACGTCA GCCCCAGGAAATGCCCGGTTTGGTCAGGGCTCAGGACCCATTGTCCTGGATGATGTGCGC TGCTCAGGACATGAGTCCTACCTGTGGAGCTGCCCCAACAATGGCTGGCTCTCCCACAAC TGTGGCCATCATGAAGATGCTGGTGTCATCTGCTCAGCTGCCCAGTCCCGGTCGACGCCC AGGCCAGACACGTTGTCGACCATCACGTTACCTCCATCGACAGTAGGATCTGAATCCAGT TTGACCCTGAGGCTGGTGAATGGAAGTGACAGGTGTCAGGGCCGAGTAGAGGTCCTATAC CGAGGCTCCTGGGGCACCGTGTGTGATGACAGCTGGGATACCAATGATGCCAATGTGGTC TGCAGGCAGCTGGGCTGTGGCTGGGCCACGTCGGCCCCAGGAAATGCCCGGTTTGGCCAG GGCTCAGGACCCATTGTTCTGGATGATGTGCGCTGCTCAGGACACGAGTCCTACCTGTGG AGCTGCCCCCACAATGGCTGGCTCTCCCACAACTGTGGCCATCATGAAGATGCTGGTGTC ATCTGCTCAGTTTCCCAGTCCCGGCCGACACCCAGTCCAGATACTTGGCCGACCTCACAT GCATCAACAGCAGGACCTGAATCCAGTTTGGCCCTGAGGCTGGTGAATGGAGGTGACAGG TGTCAGGGCCGAGTGGAGGTCCTATACCGAGGCTCCTGGGGCACCGTGTGTGATGATAGC TGGGACACCAGTGACGCCAATGTGGTCTGCCGGCAGCTGGGCTGTGGCTGGGCCACGTCA GCCCCAGGAAATGCCCGGTTTGGCCAGGGTTCAGGACCCATTGTCCTGGATGACGTGCGC TGCTCAGGCTATGAGTCCTACCTGTGGAGCTGCCCCCACAATGGCTGGCTCTCCCATAAC TGTCAGCACAGTGAAGACGCTGGTGTCATCTGCTCAGCTGCCCACTCCTGGTCGACGCCC AGTCCAGACACATTGCCGACCATCACCTTGCCTGCATCGACAGTAGGATCTGAATCCAGT TTGGCCCTGAGGCTGGTGAATGGAGGTGACAGGTGTCAGGGCCGAGTGGAGGTCCTATAC CAAGGCTCCTGGGGCACCGTGTGCGATGACAGCTGGGACACCAATGATGCCAATGTCGTC TGCAGGCAACTGGGCTGTGGCTGGGCCATGTCAGCCCCAGGAAATGCCCGGTTTGGTCAG GGCTCAGGACCCATTGTCCTGGATGATGTGCGCTGCTCAGGACACGAGTCTTACCTGTGG AGCTGCCCCCACAATGGCTGGCTCTCCCACAACTGTGGCCATAGTGAAGACGCTGGTGTC ATCTGCTCAGCTTCCCAGTCCCGGCCAACACCTAGTCCAGACACTTGGCCAACCTCACAT GCATCAACAGCAGGATCTGAATCCAGTTTGGCCCTGAGGCTGGTGAATGGAGGTGACAGG TGTCAGGGCCGAGTGGAGGTCCTATACCGAGGCTCCTGGGGCACCGTGTGTGATGACTAC TGGGACACCAATGATGCCAATGTGGTTTGCAGGCAGCTGGGCTGTGGCTGGGCCATGTCA GCCCCAGGAAATGCCCGGTTTGGCCAGGGTTCAGGACCCATTGTCCTGGATGATGTGCGC TGCTCAGGACATGAGTCCTATCTGTGGAGCTGCCCCCACAATGGCTGGCTCTCCCACAAC TGTGGCCATCATGAAGACGCTGGTGTCATCTGCTCAGCTTCCCAGTCCCAGCCGACACCC AGCCCAGACACTTGGCCAACCTCACATGCATCAACAGCAGGATCTGAATCCAGTTTGGCC CTGAGGCTGGTGAATGGAGGTGACAGGTGTCAGGGCCGAGTGGAGGTCCTATACCGAGGC TCCTGGGGCACCGTGTGTGATGACTACTGGGACACCAATGATGCCAATGTGGTTTGCAGG CAGCTGGGCTGTGGCTGGGCCACGTCAGCCCCAGGAAATGCCCGGTTTGGCCAGGGTTCA GGACCCATTGTCCTGGATGATGTGCGCTGCTCAGGACATGAGTCCTATCTGTGGAGCTGC CCCCACAATGGCTGGCTCTCCCACAACTGTGGCCATCATGAAGACGCTGGTGTCATCTGC TCAGCTTCCCAGTCCCAGCCGACACCCAGCCCAGACACTTGGCCAACCTCACATGCATCA ACAGCAGGATCTGAATCCAGTTTGGCCCTGAGGCTGGTGAATGGAGGTGACAGGTGTCAG GGCCGAGTGGAGGTCCTATACCGAGGCTCCTGGGGCACCGTGTGTGATGACTACTGGGAC ACCAATGATGCCAATGTGGTTTGCAGGCAGCTGGGCTGTGGCTGGGCCACGTCAGCCCCA GGAAATGCCCGGTTTGGCCAGGGTTCAGGACCCATTGTCCTGGATGATGTGCGCTGCTCA GGACATGAGTCCTATCTGTGGAGCTGCCCCCACAATGGCTGGCTCTCCCACAACTGTGGC CATCATGAAGACGCTGGTGTCATCTGCTCAGCTTCCCAGTCCCAGCCGACACCCAGCCCA GACACTTGGCCAACCTCTCGTGCATCAACAGCAGGATCTGAATCCACTTTGGCCCTGAGA CTGGTGAATGGAGGTGACAGGTGTCGAGGCCGAGTGGAGGTCCTATACCAAGGCTCCTGG GGCACCGTGTGTGATGACTACTGGGACACCAATGATGCCAACGTGGTCTGCAGGCAGCTG GGCTGTGGCTGGGCCATGTCAGCCCCAGGAAATGCCCAGTTTGGCCAGGGCTCAGGACCC ATTGTCCTGGATGATGTGCGCTGCTCAGGACACGAGTCTTACCTGTGGAGCTGCCCCCAC AATGGCTGGCTCTCCCACAACTGTGGCCATCATGAAGATGCTGGTGTCATCTGCTCAGCT GCTCAGTCCCAGTCAACGCCCAGGCCAGATACTTGGCTGACCACCAACTTACCGGCATTG ACAGTAGGATCTGAATCCAGTTTGGCTCTGAGGCTGGTGAATGGAGGTGACAGGTGTCGA GGCCGAGTGGAGGTCCTGTATCGAGGCTCCTGGGGAACCGTGTGTGATGACAGCTGGGAC ACCAATGATGCCAATGTGGTCTGCAGGCAGCTGGGCTGTGGCTGGGCCATGTCGGCCCCA GGAAATGCCCGGTTTGGCCAGGGCTCAGGACCCATTGTCCTGGATGATGTGCGCTGCTCA GGGAATGAGTCCTACCTGTGGAGCTGCCCCCACAAAGGCTGGCTCACCCACAACTGTGGC CATCACGAAGACGCTGGTGTCATCTGCTCAGCCACCCAAATAAATTCTACTACGACAGAT TGGTGGCATCCAACAACTACAACCACTGCAAGACCCTCTTCAAATTGTGGTGGCTTCTTA TTCTATGCCAGTGGGACATTCTCCAGCCCATCCTACCCTGCATACTACCCCAACAATGCT AAGTGTGTTTGGGAAATAGAAGTGAATTCTGGTTATCGCATAAACCTGGGCTTCAGTAAT CTGAAATTGGAGGCACACCATAACTGCAGTTTTGATTATGTTGAAATCTTTGATGGATCA TTGAATAGCAGTCTCCTGCTGGGGAAAATCTGTAATGATACCAGGCAAATATTTACATCT TCTTACAACCGAATGACCATTCACTTTCGAAGTGACATCAGTTTCCAAAACACTGGCTTT TTGGCTTGGTATAACTCCTTCCCAAGCGATGCCACCTTGAGGTTGGTCAATTTAAATTCA TCCTATGGTCTATGTGCCGGGCGTGTAGAAATTTACCATGGTGGCACCTGGGGGACAGTT TGTGATGACTCCTGGACCATTCAGGAAGCTGAGGTGGTCTGCAGACAGCTAGGGTGTGGA CGTGCAGTTTCAGCCCTTGGAAATGCATATTTTGGCTCTGGCTCTGGCCCCATCACCCTG GACGATGTAGAGTGCTCAGGGACGGAATCCACTCTCTGGCAGTGCCGGAACCGAGGCTGG TTCTCCCACAACTGTAATCATCGTGAAGATGCTGGTGTCATCTGCTCAGGAAACCATCTA TCGACACCTGCTCCTTTTCTCAACATCACCCGTCCAAACACAGATTATTCCTGCGGAGGC TTCCTATCCCAACCATCAGGGGACTTTTCCAGCCCATTCTATCCCGGGAACTATCCAAAC AATGCCAAGTGTGTGTGGGACATTGAGGTGCAAAACAACTACCGTGTGACTGTGATCTTC AGAGATGTCCAGCTTGAAGGTGGCTGCAACTATGATTATATTGAAGTTTTCGATGGCCCC TACCGCAGTTCCCCTCTCATTGCTCGAGTTTGTGATGGGGCCAGAGGCTCCTTCACTTCT TCCTCCAACTTCATGTCCATTCGCTTCATCAGTGACCACAGCATCACAAGGAGAGGGTTC CGGGCTGAGTACTACTCCAGTCCCTCCAATGACAGCACCAACCTGCTCTGTCTGCCAAAT CACATGCAAGCCAGTGTGAGCAGGAGCTATCTCCAATCCTTGGGCTTTTCTGCCAGTGAC CTTGTCATTTCCACCTGGAATGGATACTACGAGTGTCGGCCCCAGATAACGCCGAACCTG GTGATATTCACAATTCCCTACTCAGGCTGCGGCACCTTCAAGCAGGCAGACAATGACACC ATCGACTATTCCAACTTCCTCACAGCAGCTGTCTCAGGTGGCATCATCAAGAGGAGGACA GACCTCCGTATTCACGTCAGCTGCAGAATGCTTCAGAACACCTGGGTCGACACCATGTAC ATTGCTAATGACACCATCCACGTTGCTAATAACACCATCCAGGTCGAGGAAGTCCAGTAT GGCAATTTTGACGTGAACATTTCCTTTTATACTTCCTCATCTTTCTTGTATCCTGTGACC AGCCGCCCTTACTACGTGGACCTGAACCAGGACTTGTACGTTCAGGCTGAAATCCTCCAT TCTGATGCTGTACTGACCTTGTTTGTGGACACCTGCGTGGCATCACCATACTCCAATGAC TTCACGTCTTTGACTTATGATCTAATCCGGAGTGGATGCGTGAGGGATGACACCTACGGA CCCTACTCCTCGCCATCTCTTCGCATTGCCCGCTTCCGGTTCAGGGCCTTCCACTTCCTG AACCGCTTCCCCTCCGTGTACCTGCGTTGTAAAATGGTGGTGTGCAGAGCGTATGACCCC TCTTCCCGCTGCTACCGAGGCTGTGTGTTGAGGTCGAAGAGGGATGTGGGCTCCTACCAG GAAAAGGTGGACGTCGTCCTGGGTCCCATCCAGCTGCAGACCCCCCCACGCCGAGAAGAG GAGCCTCGGTAG |
| Restriction Sites | Please inquire |
| ACCN | NM_017579 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_017579.1, NP_060049.1 |
| RefSeq Size | 7656 bp |
| RefSeq ORF | 7656 bp |
| Locus ID | 1755 |
| UniProt ID | Q9UGM3 |
| Protein Families | Druggable Genome |
| Gene Summary | Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq, Mar 2016] Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (c) is shorter than isoform b. |
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