Siglec 7 (SIGLEC7) (NM_016543) Human Untagged Clone
CAT＃: SC304431
SIGLEC7 (untagged)-Human sialic acid binding Ig-like lectin 7 (SIGLEC7), transcript variant 2
CNY 6080.00
Product images
CNY 1999.00
CNY 2700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AIRM-1; AIRM1; CD328; CDw328; D-siglec; p75; p75/AIRM1; QA79; SIGLEC-7; SIGLEC19P; SIGLECP2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_016543 edited
TGAGAGAAGAACCCTGAGGAACAGACGTTCCCTCGCGGCCCTGGCACCTCCAACCCCAGA TATGCTGCTGCTGCTGCTGCTGCCCCTGCTCTGGGGGAGGGAGAGGGTGGAAGGACAGAA GAGTAACCGGAAGGATTACTCGCTGACGATGCAGAGTTCCGTGACCGTGCAAGAGGGCAT GTGTGTCCATGTGCGCTGCTCCTTCTCCTACCCAGTGGACAGCCAGACTGACTCTGACCC AGTTCATGGCTACTGGTTCCGGGCAGGGAATGATATAAGCTGGAAGGCTCCAGTGGCCAC AAACAACCCAGCTTGGGCAGTGCAGGAGGAAACTCGGGACCGATTCCACCTCCTTGGGGA CCCACAGACCAAAAATTGCACCCTGAGCATCAGAGATGCCAGAATGAGTGATGCGGGGAG ATACTTCTTTCGTATGGAGAAAGGAAATATAAAATGGAATTATAAATATGACCAGCTCTC TGTGAACGTGACAGACCCTCCTCAGAACTTGACTGTGACTGTCTTCCAAGGAGAAGGCAC AGCATCCACAGCTCTGGGGAACAGCTCATCTCTTTCAGTCCTAGAGGGCCAGTCTCTGCG CTTGGTCTGTGCTGTTGACAGCAATCCCCCTGCCAGGCTGAGCTGGACCTGGAGGAGTCT GACCCTGTACCCCTCACAGCCCTCAAACCCTCTGGTACTGGAGCTGCAAGTGCACCTGGG GGATGAAGGGGAATTCACCTGTCGAGCTCAGAACTCTCTGGGTTCCCAGCACGTTTCCCT GAACCTCTCCCTGCAACAGGAGTACACAGGCAAAATGAGGCCTGTATCAGGAGTGTTGCT GGGGGCGGTCGGGGGAGCTGGAGCCACAGCCCTGGTCTTCCTCTCCTTCTGTGTCATCTT CATTGTAGTGAGGTCCTGCAGGAAGAAATCGGCAAGGCCAGCAGCGGACGTGGGAGACAT AGGCATGAAGGATGCAAACACCATCAGGGGCTCAGCCTCTCAGGGTAACCTGACTGAGTC CTGGGCAGATGATAACCCCCGACACCATGGCCTGGCTGCCCACTCCTCAGGGGAGGAAAG AGAGATCCAGTATGCACCCCTCAGCTTTCATAAGGGGGAGCCTCAGGACCTATCAGGTCA AGAAGCCACCAACAATGAGTACTCAGAGATCAAGATCCCCAAGTAAGAAAATGCAGAGGC TCGGGCTTGTTTGAGGGTTCACGACCCCTCCAGCAAAGGAGTCTGAGGCTGATTCCAGTA GAATTAGCAGCCCTCAATGCTGTGCAACAAGACATCAGAACTTATTCCTCTTGTCTAACT GAAAATGCATGCCTGATGACCAAACTCTCCCTTTCCCCATCCAATCGGTCCACACTCCCC GCCCTGGCCTCTGGTACCCACCATTCTCCTCTGTACTTCTCTAAGGATGACTACTTTAGA TTCCGAATATAGTGAGATTGTAACGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAA |
| Restriction Sites | Please inquire |
| ACCN | NM_016543 |
| Insert Size | 1500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone is found to be a perfect match to NM_016543.1. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_016543.1, NP_057627.1 |
| RefSeq Size | 1476 bp |
| RefSeq ORF | 951 bp |
| Locus ID | 27036 |
| UniProt ID | Q9Y286 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Gene Summary | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks an in-frame coding exon, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213691 | SIGLEC7 (Myc-DDK-tagged)-Human sialic acid binding Ig-like lectin 7 (SIGLEC7), transcript variant 2 |
CNY 3656.00 |
|
| RC213691L3 | Lenti ORF clone of Human sialic acid binding Ig-like lectin 7 (SIGLEC7), transcript variant 2, Myc-DDK-tagged |
CNY 5890.00 |
|
| RC213691L4 | Lenti ORF clone of Human sialic acid binding Ig-like lectin 7 (SIGLEC7), transcript variant 2, mGFP tagged |
CNY 5890.00 |
|
| RG213691 | SIGLEC7 (tGFP-tagged) - Human sialic acid binding Ig-like lectin 7 (SIGLEC7), transcript variant 2 |
CNY 5256.00 |
|
| SC317599 | SIGLEC7 (untagged)-Human sialic acid binding Ig-like lectin 7 (SIGLEC7), transcript variant 2 |
CNY 6080.00 |
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