CLASP2 (NM_015097) Human Untagged Clone
CAT＃: SC304229
CLASP2 (untagged)-Human cytoplasmic linker associated protein 2 (CLASP2), transcript variant 1
CNY 15464.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>NCBI ORF sequence for NM_015097, the custom clone sequence may differ by one or more nucleotides
ATGGAGCCCCGCAGCATGGAGTACTTCTGCGCCCAGGTGCAGCAGAAGGACGTCGGCGGCCGGCTGCAGG TCGGCCAGGAGCTCCTGCTCTACCTTGGCGCCCCCGGCGCCATCTCGGACCTGGAGGAGGACCTGGGCCG CCTAGGCAAGACAGTCGACGCGCTCACCGGCTGGGTGGGTTCGAGCAACTACCGGGTATCATTAATGGGA TTGGAAATTTTAAGTGCCTTTGTGGACAGATTATCAACACGCTTTAAATCCTATGTAGCAATGGTTATTG TAGCTTTAATAGACAGAATGGGAGATGCCAAAGACAAGGTTCGAGATGAAGCTCAGACTCTGATATTGAA GTTAATGGATCAAGTAGCACCACCTATGTACATTTGGGAGCAGTTGGCTTCTGGTTTTAAACACAAGAAT TTTCGATCTCGAGAAGGCGTGTGTCTGTGTCTTATTGAAACCTTAAACATTTTTGGGGCTCAGCCACTAG TCATCAGCAAATTGATACCACATTTGTGTATCCTGTTTGGAGACTCCAACAGTCAGGTGAGAGATGCTGC AATATTGGCTATAGTGGAGATTTATAGACATGTGGGAGAAAAAGTGAGGATGGATCTTTATAAGAGAGGA ATTCCCCCTGCTAGATTAGAAATGATATTTGCCAAATTTGATGAAGTGCAAAGTTCAGGCGGTATGATTT TGAGTGTCTGCAAAGATAAAAGCTTCGATGATGAAGAATCAGTGGATGGAAATAGGCCATCATCAGCTGC ATCAGCCTTCAAGGTTCCTGCACCTAAAACATCCGGAAATCCTGCCAACAGTGCAAGGAAGCCTGGTTCA GCAGGTGGCCCTAAGGTTGGAGCAGGTGCTTCTAAGGAAGGAGGTGCTGGAGCAGTTGATGAAGATGATT TTATAAAAGCTTTTACAGATGTCCCTTCTATTCAGATTTATTCTAGTCGAGAACTCGAAGAAACATTAAA TAAAATCAGGGAAATTTTGTCAGATGATAAACATGACTGGGATCAGCGTGCCAATGCACTGAAGAAAATT CGATCACTGCTTGTTGCTGGAGCTGCACAGTATGATTGCTTTTTTCAACATTTACGATTGTTGGATGGAG CACTTAAACTTTCAGCTAAGGATCTTAGATCCCAGGTGGTTAGAGAAGCTTGTATTACTGTAGCCCACCT TTCAACAGTTTTGGGAAACAAGTTTGATCATGGCGCTGAAGCCATTGTACCTACACTTTTTAATCTCGTC CCCAATAGTGCAAAAGTCATGGCAACTTCTGGATGTGCAGCAATCAGATTTATCATTCGGCATACTCATG TACCCAGACTTATACCTTTAATAACAAGCAATTGCACATCAAAATCAGTTCCCGTGAGGAGACGTTCATT TGAATTTTTAGATTTATTGTTGCAAGAGTGGCAGACTCATTCATTGGAAAGACATGCAGCCGTCTTGGTT GAAACTATTAAAAAGGGAATTCATGATGCTGACGCTGAGGCCAGAGTGGAGGCAAGAAAGACATACATGG GTCTTAGAAACCACTTTCCTGGTGAAGCTGAAACATTATATAATTCCCTTGAGCCATCTTATCAGAAGAG TCTTCAAACTTACTTAAAGAGTTCTGGCAGTGTAGCATCTCTTCCACAATCAGACAGGTCCTCATCCAGC TCACAGGAAAGTCTCAATCGCCCTTTTTCTTCCAAATGGTCTACAGCAAATCCATCAACTGTGGCTGGAA GAGTATCAGCAGGCAGCAGCAAAGCCAGTTCCCTTCCAGGAAGCCTGCAGCGTTCACGAAGTGACATTGA TGTGAATGCTGCTGCAGGTGCCAAGGCACATCATGCTGCTGGACAGTCTGTGCGAAGCGGGCGCTTAGGT GCAGGTGCCCTGAATGCAGGTTCCTATGCGTCACTAGAGGATACTTCTGACAAGCTGGATGGAACAGCAT CTGAAGATGGCCGGGTGAGAGCAAAACTTTCAGCACCACTTGCTGGCATGGGAAATGCCAAGGCAGATTC TAGAGGAAGAAGTCGAACAAAAATGGTGTCTCAATCACAGCCTGGTAGCCGGTCTGGGTCTCCAGGAAGA GTTCTGACCACAACAGCCCTGTCCACTGTGAGCTCTGGTGTTCAAAGAGTCCTGGTCAATTCAGCCTCAG CACAAAAAAGAAGCAAGATACCACGGAGCCAGGGCTGTAGCAGAGAGGCTAGTCCATCTAGGCTTTCAGT GGCCCGAAGCAGTCGTATTCCTCGACCAAGTGTGAGTCAAGGATGCAGCCGGGAAGCTAGTCGGGAGAGC AGCAGAGACACAAGTCCTGTTCGCTCTTTTCAGCCCCTCGGTCCAGGTTATGGGATCAGCCAATCAAGTC GACTGTCGTCTTCTGTTAGTGCCATGCGAGTCCTGAACACAGGTTCTGATGTGGAGGAGGCGGTGGCAGA TGCCTTGCTCTTAGGAGACATACGGACTAAGAAAAAACCAGCTCGAAGAAGATATGAATCATATGGAATG CATTCAGATGATGACGCCAACAGCGATGCATCTAGTGCTTGTTCAGAACGCTCCTATAGTTCTCGAAATG GTAGTATTCCTACATATATGAGGCAGACGGAAGATGTGGCAGAAGTCCTCAATAGATGTGCTAGTTCCAA TTGGTCAGAAAGGAAAGAAGGCCTCCTAGGTCTGCAGAACTTATTAAAAAATCAGAGAACACTAAGTCGA GTTGAACTGAAAAGATTATGTGAAATTTTCACAAGAATGTTTGCTGACCCTCATGGCAAGAGAGTATTCA GCATGTTTTTGGAGACTCTAGTGGATTTCATACAAGTCCACAAAGATGATCTTCAAGATTGGTTGTTTGT ACTGCTGACACAACTACTAAAAAAAATGGGTGCTGATTTGCTTGGATCTGTTCAGGCAAAAGTTCAGAAA GCCCTTGATGTTACAAGAGAGTCTTTTCCAAATGATCTTCAGTTCAATATTCTAATGAGATTTACAGTTG ATCAGACCCAGACACCAAGCTTAAAGGTGAAGGTTGCTATCCTTAAATACATAGAAACTCTGGCCAAACA GATGGATCCAGGAGATTTTATAAATTCCAGTGAAACTCGCCTAGCAGTGTCTCGGGTCATCACTTGGACA ACAGAACCCAAAAGTTCTGATGTTCGGAAGGCAGCACAGTCAGTGCTGATTTCATTATTTGAACTCAATA CCCCAGAGTTTACAATGTTATTAGGAGCTTTACCAAAAACTTTTCAGGATGGTGCTACCAAGCTTCTTCA TAATCACCTTCGAAACACTGGCAATGGAACCCAGAGTTCCATGGGGAGTCCTTTGACAAGACCAACACCA CGATCACCAGCTAACTGGTCCAGTCCTCTTACTTCTCCTACCAATACATCACAGAATACTTTATCTCCAA GTGCATTTGATTATGACACAGAAAATATGAACTCTGAAGATATTTATAGCTCTCTTAGAGGTGTCACTGA AGCAATCCAGAATTTCAGCTTCCGTAGCCAAGAAGATATGAATGAGCCATTGAAAAGGGATTCTAAAAAA GATGATGGCGATTCAATGTGTGGTGGTCCTGGGATGTCTGACCCAAGAGCAGGAGGTGATGCTACTGACT CAAGTCAAACAGCTCTTGATAATAAAGCTTCATTGCTCCATTCAATGCCTACTCACTCCTCTCCACGCTC TCGAGACTATAATCCATATAACTATTCAGATAGCATCAGTCCCTTCAACAAGTCTGCCCTCAAGGAAGCC ATGTTTGATGATGATGCTGACCAGTTTCCTGACGATCTTTCCCTAGATCATTCTGACCTAGTTGCAGAGT TGTTGAAGGAGCTGTCTAACCATAATGAGCGTGTAGAAGAAAGAAAAATTGCCCTCTATGAACTTATGAA ACTGACACAGGAAGAATCTTTTAGTGTTTGGGATGAACACTTCAAAACAATATTGCTTTTATTGCTTGAA ACGCTTGGAGATAAAGAGCCTACAATCAGGGCTTTGGCATTAAAGGTTTTAAGAGAAATCCTAAGGCATC AACCAGCAAGATTTAAAAACTATGCAGAATTGACTGTCATGAAAACATTGGAAGCACATAAAGATCCTCA TAAGGAGGTGGTGAGATCTGCTGAGGAAGCGGCATCAGTGTTGGCCACTTCAATTAGTCCAGAGCAGTGC ATCAAAGTGCTTTGTCCTATCATTCAAACTGCAGACTACCCAATTAATCTGGCTGCAATCAAAATGCAAA CAAAAGTGATAGAGAGAGTGTCCAAGGAAACCCTAAACCTGCTTTTGCCAGAGATTATGCCAGGTCTAAT ACAGGGTTATGATAATTCAGAGAGCAGTGTTCGGAAAGCTTGTGTCTTCTGCCTGGTGGCTGTTCATGCG GTAATTGGTGATGAACTAAAACCACATCTCAGTCAACTTACTGGCAGTAAAATGAAGCTACTGAATCTTT ACATCAAACGTGCACAAACAGGTTCTGGAGGAGCTGATCCCACTACTGATGTTTCTGGACAAAGTTAG |
| Restriction Sites | Please inquire |
| ACCN | NM_015097 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_015097.1, NP_055912.1 |
| RefSeq Size | 7289 bp |
| RefSeq ORF | 4521 bp |
| Locus ID | 23122 |
| UniProt ID | O75122 |
| Gene Summary | Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer variant and encodes the longer isoform (1). |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220105 | CLASP2 (Myc-DDK-tagged)-Human cytoplasmic linker associated protein 2 (CLASP2), transcript variant 1 |
CNY 15456.00 |
|
| RC220105L3 | Lenti ORF clone of Human cytoplasmic linker associated protein 2 (CLASP2), transcript variant 1, Myc-DDK-tagged |
CNY 16910.00 |
|
| RC220105L4 | Lenti ORF clone of Human cytoplasmic linker associated protein 2 (CLASP2), transcript variant 1, mGFP tagged |
CNY 16910.00 |
|
| RG220105 | CLASP2 (tGFP-tagged) - Human cytoplasmic linker associated protein 2 (CLASP2), transcript variant 1 |
CNY 16530.00 |
