gp340 (DMBT1) (NM_004406) Human Untagged Clone
CAT＃: SC303478
DMBT1 (untagged)-Human deleted in malignant brain tumors 1 (DMBT1), transcript variant 1
CNY 34390.00
货期*
9周
规格
Product images
推荐一起购买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GP340; muclin; SAG; SALSA |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_004406, the custom clone sequence may differ by one or more nucleotides
ATGGGGATCTCCACAGTCATCCTTGAAATGTGTCTTTTATGGGGACAAGTTCTATCTACA GGTGGGTGGATCCCAAGGACTACAGACTACGCTTCACTGATTCCCTCGGAGGTGCCCTTG GATCCAACTGTAGCAGAAGGTTCTCCATTTCCCTCGGAGTCGACCCTGGAGTCAACTGTA GCAGAAGGTTCTCCGATTTCCTTGGAGTCAACCCTGGAGTCAACCGTAGCAGAAGGTTCT CTGATTCCCTCAGAGTCAACCCTGGAGTCAACTGTAGCAGAAGGATCTGATTCTGGTTTG GCCCTGAGGCTGGTGAATGGAGATGGCAGGTGTCAGGGCCGAGTGGAGATCCTATACCGA GGCTCCTGGGGCACCGTGTGTGATGACAGCTGGGACACCAATGATGCCAACGTGGTCTGT AGGCAGCTGGGTTGTGGCTGGGCCATGTCAGCTCCAGGAAATGCCTGGTTTGGCCAGGGC TCAGGACCCATTGCCCTGGATGATGTGCGCTGCTCAGGACACGAATCCTACCTGTGGAGC TGCCCCCACAATGGCTGGCTCTCCCATAACTGTGGCCATGGTGAAGATGCTGGTGTTATC TGCTCAGCTGCCCAGCCTCAGTCAACACTCAGGCCAGAAAGTTGGCCTGTCAGGATATCA CCACCTGTACCCACAGAAGGATCTGAATCCAGTTTGGCCCTGAGGCTGGTGAATGGAGGC GACAGGTGTCGAGGCCGAGTGGAGGTCCTATACCGAGGCTCCTGGGGCACCGTGTGTGAT GACTACTGGGACACCAATGATGCCAATGTGGTCTGCAGGCAGCTGGGCTGTGGCTGGGCC ATGTCAGCCCCAGGAAATGCCCAGTTTGGCCAGGGCTCAGGACCCATTGTCCTGGATGAT GTGCGCTGCTCAGGACATGAGTCCTACCTGTGGAGCTGCCCCCACAATGGCTGGCTCACC CACAACTGTGGCCATAGTGAAGACGCTGGTGTCATCTGCTCAGCTCCCCAGTCCCGGCCG ACACCCAGCCCAGATACTTGGCCGACCTCACATGCATCAACAGCAGGACCTGAATCCAGT TTGGCCCTGAGGCTGGTGAATGGAGGTGACAGGTGTCAGGGCCGAGTGGAGGTCCTATAC CGAGGCTCCTGGGGCACCGTGTGTGATGATAGCTGGGACACCAGTGACGCCAATGTGGTC TGCCGGCAGCTGGGCTGTGGCTGGGCCACGTCAGCCCCAGGAAATGCCCGGTTTGGCCAG GGTTCAGGACCCATTGTCCTGGATGACGTGCGCTGCTCAGGCTATGAGTCCTACCTGTGG AGCTGCCCCCACAATGGCTGGCTCTCCCATAACTGTCAGCACAGTGAAGACGCTGGTGTC ATCTGCTCAGCTGCCCACTCCTGGTCGACGCCCAGTCCAGACACATTGCCGACCATCACC TTGCCTGCATCGACAGTAGGATCTGAATCCAGTTTGGCCCTGAGGCTGGTGAATGGAGGT GACAGGTGTCAGGGCCGAGTGGAGGTCCTATACCAAGGCTCCTGGGGCACCGTGTGCGAT GACAGCTGGGACACCAATGATGCCAATGTCGTCTGCAGGCAACTGGGCTGTGGCTGGGCC ATGTCAGCCCCAGGAAATGCCCGGTTTGGTCAGGGCTCAGGACCCATTGTCCTGGATGAT GTGCGCTGCTCAGGACACGAGTCTTACCTGTGGAGCTGCCCCCACAATGGCTGGCTCTCC CACAACTGTGGCCATAGTGAAGACGCTGGTGTCATCTGCTCAGCTTCCCAGTCCCGGCCA ACACCTAGTCCAGACACTTGGCCAACCTCACATGCATCAACAGCAGGATCTGAATCCAGT TTGGCCCTGAGGCTGGTGAATGGAGGTGACAGGTGTCAGGGCCGAGTGGAGGTCCTATAC CGAGGCTCCTGGGGCACCGTGTGTGATGACTACTGGGACACCAATGATGCCAATGTGGTT TGCAGGCAGCTGGGCTGTGGCTGGGCCATGTCAGCCCCAGGAAATGCCCGGTTTGGCCAG GGTTCAGGACCCATTGTCCTGGATGATGTGCGCTGCTCAGGACATGAGTCCTATCTGTGG AGCTGCCCCCACAATGGCTGGCTCTCCCACAACTGTGGCCATCATGAAGACGCTGGTGTC ATCTGCTCAGCTTCCCAGTCCCAGCCGACACCCAGCCCAGACACTTGGCCAACCTCACAT GCATCAACAGCAGGATCTGAATCCAGTTTGGCCCTGAGGCTGGTGAATGGAGGTGACAGG TGTCAGGGCCGAGTGGAGGTCCTATACCGAGGCTCCTGGGGCACCGTGTGTGATGACTAC TGGGACACCAATGATGCCAATGTGGTTTGCAGGCAGCTGGGCTGTGGCTGGGCCACGTCA GCCCCAGGAAATGCCCGGTTTGGCCAGGGTTCAGGACCCATTGTCCTGGATGATGTGCGC TGCTCAGGACATGAGTCCTATCTGTGGAGCTGCCCCCACAATGGCTGGCTCTCCCACAAC TGTGGCCATCATGAAGACGCTGGTGTCATCTGCTCAGCTTCCCAGTCCCAGCCGACACCC AGCCCAGACACTTGGCCAACCTCTCGTGCATCAACAGCAGGATCTGAATCCACTTTGGCC CTGAGACTGGTGAATGGAGGTGACAGGTGTCGAGGCCGAGTGGAGGTCCTATACCAAGGC TCCTGGGGCACCGTGTGTGATGACTACTGGGACACCAATGATGCCAACGTGGTCTGCAGG CAGCTGGGCTGTGGCTGGGCCATGTCAGCCCCAGGAAATGCCCAGTTTGGCCAGGGCTCA GGACCCATTGTCCTGGATGATGTGCGCTGCTCAGGACACGAGTCTTACCTGTGGAGCTGC CCCCACAATGGCTGGCTCTCCCACAACTGTGGCCATCATGAAGATGCTGGTGTCATCTGC TCAGCTGCTCAGTCCCAGTCAACGCCCAGGCCAGATACTTGGCTGACCACCAACTTACCG GCATTGACAGTAGGATCTGAATCCAGTTTGGCTCTGAGGCTGGTGAATGGAGGTGACAGG TGTCGAGGCCGAGTGGAGGTCCTGTATCGAGGCTCCTGGGGAACCGTGTGTGATGACAGC TGGGACACCAATGATGCCAATGTGGTCTGCAGGCAGCTGGGCTGTGGCTGGGCCATGTCG GCCCCAGGAAATGCCCGGTTTGGCCAGGGCTCAGGACCCATTGTCCTGGATGATGTGCGC TGCTCAGGGAATGAGTCCTACCTGTGGAGCTGCCCCCACAAAGGCTGGCTCACCCACAAC TGTGGCCATCACGAAGACGCTGGTGTCATCTGCTCAGCCACCCAAATAAATTCTACTACG ACAGATTGGTGGCATCCAACAACTACAACCACTGCAAGACCCTCTTCAAATTGTGGTGGC TTCTTATTCTATGCCAGTGGGACATTCTCCAGCCCATCCTACCCTGCATACTACCCCAAC AATGCTAAGTGTGTTTGGGAAATAGAAGTGAATTCTGGTTATCGCATAAACCTGGGCTTC AGTAATCTGAAATTGGAGGCACACCATAACTGCAGTTTTGATTATGTTGAAATCTTTGAT GGATCATTGAATAGCAGTCTCCTGCTGGGGAAAATCTGTAATGATACCAGGCAAATATTT ACATCTTCTTACAACCGAATGACCATTCACTTTCGAAGTGACATCAGTTTCCAAAACACT GGCTTTTTGGCTTGGTATAACTCCTTCCCAAGCGATGCCACCTTGAGGTTGGTCAATTTA AATTCATCCTATGGTCTATGTGCCGGGCGTGTAGAAATTTACCATGGTGGCACCTGGGGG ACAGTTTGTGATGACTCCTGGACCATTCAGGAAGCTGAGGTGGTCTGCAGACAGCTAGGG TGTGGACGTGCAGTTTCAGCCCTTGGAAATGCATATTTTGGCTCTGGCTCTGGCCCCATC ACCCTGGACGATGTAGAGTGCTCAGGGACGGAATCCACTCTCTGGCAGTGCCGGAACCGA GGCTGGTTCTCCCACAACTGTAATCATCGTGAAGATGCTGGTGTCATCTGCTCAGGAAAC CATCTATCGACACCTGCTCCTTTTCTCAACATCACCCGTCCAAACACAGATTATTCCTGC GGAGGCTTCCTATCCCAACCATCAGGGGACTTTTCCAGCCCATTCTATCCCGGGAACTAT CCAAACAATGCCAAGTGTGTGTGGGACATTGAGGTGCAAAACAACTACCGTGTGACTGTG ATCTTCAGAGATGTCCAGCTTGAAGGTGGCTGCAACTATGATTATATTGAAGTTTTCGAT GGCCCCTACCGCAGTTCCCCTCTCATTGCTCGAGTTTGTGATGGGGCCAGAGGCTCCTTC ACTTCTTCCTCCAACTTCATGTCCATTCGCTTCATCAGTGACCACAGCATCACAAGGAGA GGGTTCCGGGCTGAGTACTACTCCAGTCCCTCCAATGACAGCACCAACCTGCTCTGTCTG CCAAATCACATGCAAGCCAGTGTGAGCAGGAGCTATCTCCAATCCTTGGGCTTTTCTGCC AGTGACCTTGTCATTTCCACCTGGAATGGATACTACGAGTGTCGGCCCCAGATAACGCCG AACCTGGTGATATTCACAATTCCCTACTCAGGCTGCGGCACCTTCAAGCAGGCAGACAAT GACACCATCGACTATTCCAACTTCCTCACAGCAGCTGTCTCAGGTGGCATCATCAAGAGG AGGACAGACCTCCGTATTCACGTCAGCTGCAGAATGCTTCAGAACACCTGGGTCGACACC ATGTACATTGCTAATGACACCATCCACGTTGCTAATAACACCATCCAGGTCGAGGAAGTC CAGTATGGCAATTTTGACGTGAACATTTCCTTTTATACTTCCTCATCTTTCTTGTATCCT GTGACCAGCCGCCCTTACTACGTGGACCTGAACCAGGACTTGTACGTTCAGGCTGAAATC CTCCATTCTGATGCTGTACTGACCTTGTTTGTGGACACCTGCGTGGCATCACCATACTCC AATGACTTCACGTCTTTGACTTATGATCTAATCCGGAGTGGATGCGTGAGGGATGACACC TACGGACCCTACTCCTCGCCATCTCTTCGCATTGCCCGCTTCCGGTTCAGGGCCTTCCAC TTCCTGAACCGCTTCCCCTCCGTGTACCTGCGTTGTAAAATGGTGGTGTGCAGAGCGTAT GACCCCTCTTCCCGCTGCTACCGAGGCTGTGTGTTGAGGTCGAAGAGGGATGTGGGCTCC TACCAGGAAAAGGTGGACGTCGTCCTGGGTCCCATCCAGCTGCAGACCCCCCCACGCCGA GAAGAGGAGCCTCGGTAG |
| Restriction Sites | Please inquire |
| ACCN | NM_004406 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004406.1, NP_004397.1 |
| RefSeq Size | 5802 bp |
| RefSeq ORF | 5802 bp |
| Locus ID | 1755 |
| UniProt ID | Q9UGM3 |
| Protein Families | Druggable Genome |
| Gene Summary | Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq, Mar 2016] Transcript Variant: This variant (1) lacks multiple in-frame exons in the coding region compared to variant 2. The encoded isoform (a) is shorter than isoform b. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Customer
Reviews
Loading...
