Filamin B (FLNB) (NM_001457) Human Untagged Clone
CAT＃: SC303025
FLNB (untagged)-Human filamin B, beta (FLNB), transcript variant 2
CNY 50070.00
货期*
12周
规格
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ABP-278; ABP-280; AOI; FH1; FLN-B; FLN1L; LRS1; SCT; TABP; TAP |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001457, the custom clone sequence may differ by one or more nucleotides
ATGCCGGTAACCGAGAAGGATCTAGCTGAGGACGCGCCTTGGAAGAAGATCCAGCAGAAC ACGTTCACACGCTGGTGCAACGAGCACCTCAAGTGCGTGAACAAACGCATCGGCAACCTG CAGACCGACCTGAGCGACGGGCTGCGGCTCATCGCGCTGCTCGAGGTGCTCAGCCAGAAG CGCATGTACCGCAAGTACCATCAGCGGCCCACCTTTCGCCAGATGCAGCTCGAGAATGTG TCCGTGGCGCTCGAGTTCCTGGACCGTGAGAGCATCAAGCTCGTGTCCATCGATAGCAAA GCCATTGTGGATGGGAACCTGAAGCTCATCTTGGGTCTGGTGTGGACGCTGATCCTCCAC TACTCCATCTCCATGCCCGTGTGGGAGGATGAAGGGGATGATGATGCCAAGAAGCAGACG CCAAAGCAGAGGCTGCTGGGGTGGATTCAGAACAAGATCCCCTACTTGCCCATCACCAAC TTTAACCAGAACTGGCAAGACGGCAAAGCCCTGGGAGCCCTGGTAGACAGCTGTGCTCCA GGTCTGTGCCCAGACTGGGAATCCTGGGACCCGCAGAAGCCTGTGGATAATGCACGAGAA GCCATGCAGCAGGCAGATGACTGGCTGGGTGTCCCACAGGTCATCACTCCTGAAGAAATC ATTCACCCGGATGTGGACGAGCACTCAGTTATGACTTACCTGTCCCAGTTCCCCAAAGCC AAGCTCAAGCCGGGGGCTCCTCTCAAACCCAAACTCAACCCGAAGAAAGCCAGGGCCTAT GGCAGAGGAATCGAGCCCACTGGAAACATGGTGAAGCAGCCAGCCAAGTTCACTGTGGAC ACCATCAGCGCCGGGCAAGGAGACGTGATGGTGTTTGTTGAGGACCCAGAAGGGAACAAA GAGGAGGCACAAGTGACCCCTGACAGTGACAAGAACAAGACATACTCTGTGGAGTATCTG CCCAAGGTCACCGGGCTACACAAAGTCACAGTCCTCTTTGCAGGACAGCACATCTCCAAG AGCCCATTTGAAGTGAGTGTTGACAAGGCCCAGGGAGATGCCAGTAAAGTCACTGCAAAA GGTCCAGGGTTGGAAGCTGTAGGGAACATCGCCAATAAGCCCACCTACTTTGACATCTAT ACGGCAGGAGCTGGTGTGGGTGACATTGGTGTGGAGGTGGAAGATCCCCAGGGGAAGAAC ACCGTGGAGTTGCTCGTGGAAGACAAAGGAAACCAGGTGTATCGATGTGTGTACAAACCC ATGCAGCCTGGCCCTCACGTGGTCAAGATCTTCTTTGCTGGGGACACTATTCCTAAGAGT CCCTTCGTTGTGCAGGTTGGGGAAGCCTGCAATCCAAATGCCTGCCGGGCCAGTGGCCGA GGCCTACAACCCAAAGGCGTCCGTATCCGGGAGACCACAGATTTCAAGGTTGACACCAAA GCTGCAGGAAGTGGGGAGCTCGGTGTAACCATGAAGGGTCCTAAGGGTCTGGAGGAGCTG GTGAAGCAGAAAGACTTTCTGGATGGGGTCTACGCATTCGAGTATTACCCCAGCACCCCG GGGAGATACAGCATTGCCATCACATGGGGGGGACACCACATTCCAAAGAGCCCCTTTGAA GTTCAAGTTGGCCCTGAAGCGGGTATGCAGAAAGTCCGTGCTTGGGGCCCTGGGCTCCAT GGTGGGATTGTCGGGCGGTCAGCGGACTTCGTGGTAGAATCCATTGGCTCTGAAGTGGGG TCTCTGGGGTTTGCCATTGAAGGCCCCTCTCAGGCAAAGATTGAGTACAACGACCAGAAT GATGGATCGTGTGATGTCAAATACTGGCCCAAGGAGCCTGGCGAATATGCTGTTCACATC ATGTGTGACGACGAAGACATCAAGGACAGCCCGTACATGGCCTTCATCCACCCAGCCACG GGAGGCTACAACCCTGATCTGGTTCGAGCATACGGGCCAGGTTTGGAGAAATCTGGATGC ATTGTCAACAACCTGGCCGAGTTCACTGTGGATCCTAAGGATGCTGGAAAAGCTCCCTTA AAGATATTTGCTCAGGATGGGGAAGGCCAACGCATTGACATCCAGATGAAGAACCGGATG GACGGCACATATGCATGCTCATACACCCCGGTGAAGGCCATCAAGCACACCATTGCTGTG GTCTGGGGAGGCGTGAACATCCCGCACAGCCCCTACAGGGTCAACATCGGGCAAGGTAGC CATCCTCAGAAGGTCAAAGTGTTTGGGCCAGGTGTGGAGAGAAGTGGTCTGAAGGCAAAT GAACCTACACACTTCACGGTGGACTGTACTGAGGCTGGGGAAGGTGATGTCAGTGTTGGC ATTAAGTGTGATGCCCGGGTGTTAAGTGAAGATGAGGAAGACGTGGATTTTGACATTATT CACAATGCCAATGATACGTTCACAGTCAAATATGTGCCTCCTGCTGCTGGGCGATACACT ATCAAAGTTCTCTTTGCATCTCAGGAAATCCCCGCCAGCCCTTTCAGAGTCAAAGTTGAC CCTTCCCACGATGCCAGCAAAGTGAAGGCAGAAGGCCCAGGGCTCAGCAAAGCAGGTGTG GAAAATGGGAAACCGACCCACTTCACTGTCTACACCAAGGGGGCTGGGAAAGCCCCGCTC AACGTGCAGTTCAACAGCCCTCTTCCTGGCGATGCAGTGAAGGATTTGGATATCATCGAT AATTATGACTACTCTCACACGGTTAAATATACACCCACCCAACAGGGCAACATGCAGGTT CTGGTGACTTACGGTGGCGATCCCATCCCTAAAAGCCCTTTCACTGTGGGTGTTGCTGCA CCGCTGGATCTGAGCAAGATAAAACTCAATGGGCTGGAAAACAGGGTGGAAGTTGGGAAG GATCAGGAGTTCACCGTTGATACCAGGGGGGCAGGAGGCCAGGGGAAGCTGGACGTGACA ATCCTCAGCCCCTCTCGGAAGGTCGTGCCATGCCTAGTGACACCTGTGACAGGCCGGGAG AACAGCACGGCCAAGTTCATCCCTCGGGAGGAGGGGCTGTATGCTGTAGACGTGACCTAC GATGGACACCCTGTGCCCGGGAGCCCCTACACAGTGGAGGCCTCGCTGCCACCAGATCCC AGCAAGGTGAAGGCCCACGGTCCCGGCCTCGAAGGTGGTCTCGTGGGCAAGCCTGCCGAG TTCACCATCGATACCAAAGGAGCTGGTACTGGAGGTCTGGGCTTAACGGTGGAAGGTCCG TGCGAGGCCAAAATCGAGTGCTCCGACAATGGTGATGGGACCTGCTCCGTCTCTTACCTT CCCACAAAACCCGGGGAGTACTTCGTCAACATCCTCTTTGAAGAAGTCCACATACCTGGG TCTCCCTTCAAAGCTGACATTGAAATGCCCTTTGACCCCTCTAAAGTCGTGGCATCGGGG CCAGGTCTCGAGCACGGGAAGGTGGGTGAAGCTGGCCTCCTTAGCGTCGACTGCTCGGAA GCGGGACCGGGGGCCCTGGGCCTGGAAGCTGTCTCGGACTCGGGAACAAAAGCCGAAGTC AGTATTCAGAACAACAAAGATGGCACCTACGCGGTGACCTACGTGCCCCTGACGGCCGGC ATGTACACGTTGACCATGAAGTATGGTGGCGAACTCGTGCCACACTTCCCCGCCCGGGTC AAGGTGGAGCCCGCCGTGGACACCAGCAGGATCAAAGTCTTTGGACCAGGAATAGAAGGG AAAGATGTGTTCCGGGAAGCTACCACCGACTTTACAGTTGACTCTCGGCCGCTGACCCAG GTTGGGGGTGACCACATCAAGGCCCACATTGCCAACCCCTCAGGGGCCTCCACCGAGTGC TTTGTCACAGACAATGCGGATGGGACCTACCAGGTGGAATACACACCCTTTGAGAAAGGT CTCCATGTAGTGGAGGTGACATATGATGACGTGCCTATCCCAAACAGTCCCTTCAAGGTG GCTGTCACTGAAGGCTGCCAGCCATCTAGGGTGCAAGCCCAAGGACCTGGATTGAAAGAG GCCTTTACCAACAAGCCCAATGTCTTCACCGTGGTTACCAGAGGCGCAGGAATTGGTGGG CTTGGCATAACTGTTGAGGGACCATCAGAGTCGAAGATAAATTGCAGAGACAACAAGGAT GGCAGCTGCAGTGCTGAGTACATTCCTTTCGCACCGGGGGATTACGATGTTAATATCACA TATGGAGGAGCCCACATCCCCGGCAGCCCCTTCAGGGTTCCTGTGAAGGATGTTGTGGAC CCCAGCAAGGTCAAGATTGCCGGCCCCGGGCTGGGCTCAGGCGTCCGAGCCCGTGTCCTG CAGTCCTTCACGGTGGACAGCAGCAAGGCTGGCCTGGCTCCGCTGGAAGTGAGGGTTCTG GGCCCACGAGGCTTGGTGGAGCCAGTGAACGTGGTGGACAATGGAGATGGCACACACACA GTAACCTACACCCCATCTCAGGAGGGACCTTACATGGTCTCAGTTAAATATGCTGATGAA GAGATTCCTCGCAGTCCCTTCAAGGTCAAGGTCCTTCCCACATATGATGCCAGCAAAGTG ACTGCCAGTGGCCCCGGCCTTAGTTCCTATGGTGTGCCTGCCAGTCTACCTGTGGACTTT GCAATTGATGCCCGAGATGCCGGGGAAGGCCTGCTTGCTGTTCAAATAACGGACCAAGAA GGAAAACCCAAAAGAGCCATTGTCCATGACAATAAAGATGGCACGTATGCTGTCACCTAC ATCCCCGACAAGACTGGGCGCTATATGATTGGAGTCACCTACGGGGGTGACGACATCCCA CTTTCTCCTTATCGCATCCGAGCCACACAGACGGGTGATGCCAGCAAGTGCCTGGCCACG GGTCCTGGAATCGCCTCCACTGTGAAAACTGGCGAAGAAGTAGGCTTTGTGGTTGATGCC AAGACTGCCGGGAAGGGTAAAGTGACCTGCACGGTTCTGACCCCAGATGGCACTGAGGCC GAGGCCGATGTCATTGAGAATGAAGATGGAACCTATGACATCTTCTACACAGCTGCCAAG CCGGGCACATATGTGATCTATGTGCGCTTCGGTGGTGTTGATATTCCTAACAGCCCCTTC ACTGTCATGGCCACAGATGGGGAAGTCACAGCCGTGGAGGAGGCACCGGTAAATGCATGT CCCCCTGGATTCAGGCCCTGGGTGACCGAAGAGGCCTATGTCCCAGTGAGTGACATGAAC GGCCTGGGATTTAAGCCTTTTGACCTGGTCATTCCGTTTGCTGTCAGGAAAGGAGAAATC ACTGGAGAGGTCCACATGCCTTCTGGGAAGACAGCCACACCTGAGATTGTGGACAACAAG GACGGCACGGTCACTGTTAGATATGCCCCCACTGAGGTCGGGCTCCATGAGATGCACATC AAATACATGGGCAGCCACATCCCTGAGAGCCCACTCCAGTTCTACGTGAACTACCCCAAC AGTGGAAGTGTTTCTGCATACGGTCCAGGCCTCGTGTATGGAGTGGCCAACAAAACTGCC ACCTTCACCATCGTCACAGAGGATGCAGGAGAAGGTGGTCTGGACTTGGCTATTGAGGGC CCCTCAAAAGCAGAAATCAGCTGCATTGACAATAAAGATGGGACATGCACAGTGACCTAC CTGCCGACTCTGCCAGGCGACTACAGCATTCTGGTCAAGTACAATGACAAGCACATCCCT GGCAGCCCCTTCACAGCCAAGATCACAGATGACAGCAGGCGGTGCTCCCAGGTGAAGTTG GGCTCAGCCGCTGACTTCCTGCTCGACATCAGTGAGACTGACCTCAGCAGCCTGACGGCC AGCATTAAGGCCCCATCTGGCCGAGACGAGCCCTGTCTCCTGAAGAGGCTGCCCAACAAC CACATTGGCATCTCCTTCATCCCCCGGGAAGTGGGCGAACATCTGGTCAGCATCAAGAAA AATGGCAACCATGTGGCCAACAGCCCCGTGTCTATCATGGTGGTCCAGTCGGAGATTGGT GACGCCCGCCGAGCCAAAGTCTATGGCCGCGGCCTGTCAGAAGGCCGGACTTTCGAGATG TCTGACTTCATCGTGGACACAAGGGATGCAGGTTATGGTGGCATATCCTTGGCGGTGGAA GGCCCCAGCAAAGTGGACATCCAGACGGAGGACCTGGAAGATGGCACCTGCAAAGTCTCC TACTTCCCTACCGTGCCTGGGGTTTATATCGTCTCCACCAAATTCGCTGACGAGCACGTG CCTGGGAGCCCATTTACCGTGAAGATCAGTGGGGAGGGAAGAGTCAAAGAGAGCATCACC CGCACCAGTCGGGCCCCGTCCGTGGCCACTGTCGGGAGCATTTGTGACCTGAACCTGAAA ATCCCAGAAATCAACAGCAGTGATATGTCGGCCCACGTCACCAGCCCCTCTGGCCGTGTG ACTGAGGCAGAGATTGTGCCCATGGGGAAGAACTCACACTGCGTCCGGTTTGTGCCCCAG GAGATGGGCGTGCACACGGTCAGCGTCAAGTACCGTGGGCAGCACGTCACCGGCAGCCCC TTCCAGTTCACCGTGGGGCCACTTGGTGAAGGAGGCGCCCACAAGGTGCGGGCAGGAGGC CCTGGCCTGGAGAGAGGAGAAGCGGGAGTCCCAGCTGAGTTCAGCATTTGGACCCGGGAA GCAGGCGCTGGAGGCCTCTCCATCGCTGTTGAGGGCCCCAGTAAGGCCGAGATTACATTC GATGACCATAAAAATGGGTCGTGCGGTGTATCTTATATTGCCCAAGAGCCTGGTAACTAC GAGGTGTCCATCAAGTTCAATGATGAGCACATCCCGGAAAGCCCCTACCTGGTGCCGGTC ATCGCACCCTCCGACGACGCCCGCCGCCTCACTGTTATGAGCCTTCAGGAATCGGGATTA AAAGTTAACCAGCCAGCATCCTTTGCTATAAGGTTGAATGGCGCAAAAGGCAAGATTGAT GCAAAGGTGCACAGCCCCTCTGGAGCCGTGGAGGAGTGCCACGTGTCTGAGCTGGAGCCA GATAAGTATGCTGTTCGCTTCATCCCTCATGAGAATGGTGTCCACACCATCGATGTCAAG TTCAATGGGAGCCACGTGGTTGGAAGCCCCTTCAAAGTGCGCGTTGGGGAGCCTGGACAA GCGGGGAACCCTGCCCTGGTGTCCGCCTATGGCACGGGACTCGAAGGGGGCACCACAGGT ATCCAGTCGGAATTCTTTATTAACACCACCCGAGCAGGTCCAGGGACATTATCCGTCACC ATCGAAGGCCCATCCAAGGTTAAAATGGATTGCCAGGAAACACCTGAAGGGTACAAAGTC ATGTACACCCCCATGGCTCCTGGTAACTACCTGATCAGCGTCAAATACGGTGGGCCCAAC CACATCGTGGGCAGTCCCTTCAAGGCCAAGGTGACAGGCCAGCGTCTAGTTAGCCCTGGC TCAGCCAACGAGACCTCATCCATCCTGGTGGAGTCAGTGACCAGGTCGTCTACAGAGACC TGCTATAGCGCCATTCCCAAGGCATCCTCGGACGCCAGCAAGGTGACCTCTAAGGGGGCA GGGCTCTCAAAGGCCTTTGTGGGCCAGAAGAGTTCCTTCCTGGTGGACTGCAGCAAAGCT GGCTCCAACATGCTGCTGATCGGGGTCCATGGGCCCACCACCCCCTGCGAGGAGGTCTCC ATGAAGCATGTAGGCAACCAGCAATACAACGTCACATACGTCGTCAAGGAGAGGGGCGAT TATGTGCTGGCTGTGAAGTGGGGGGAGGAACACATCCCTGGCAGCCCTTTTCATGTCACA GTGCCTTAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001457 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001457.1, NP_001448.1 |
| RefSeq Size | 9432 bp |
| RefSeq ORF | 7809 bp |
| Locus ID | 2317 |
| UniProt ID | O75369 |
| Protein Pathways | Focal adhesion, MAPK signaling pathway |
| Gene Summary | This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Nov 2009] Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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