FLG2 (NM_001014342) Human Untagged Clone
CAT＃: SC301923
FLG2 (untagged)-Human filaggrin family member 2 (FLG2)
CNY 46080.00
货期*
8周
规格
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IFPS; PSS6 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001014342, the custom clone sequence may differ by one or more nucleotides
ATGACCGACCTCTTGAGAAGTGTTGTCACCGTAATTGATGTTTTCTACAAATACACCAAG CAAGATGGGGAGTGTGGCACACTGAGCAAGGGTGAACTAAAGGAACTTCTGGAGAAAGAG CTTCATCCAGTTCTGAAGAACCCAGATGATCCAGACACAGTGGATGTCATCATGCATATG CTGGATCGAGATCATGACAGAAGATTGGACTTTACTGAGTTTCTTTTGATGATATTCAAG CTGACTATGGCCTGCAACAAGGTCCTCAGCAAAGAATACTGCAAAGCTTCAGGGTCAAAG AAGCATAGGCGTGGTCACCGACACCAAGAAGAAGAAAGTGAAACAGAAGAGGATGAAGAG GATACACCAGGACATAAATCAGGTTACAGACATTCAAGTTGGAGTGAGGGAGAGGAGCAT GGATATAGTTCTGGGCACTCAAGGGGAACTGTGAAATGTAGACATGGGTCCAACTCCAGG AGGCTAGGAAGACAAGGTAATTTATCCAGCTCTGGGAACCAAGAGGGATCTCAGAAAAGA TACCACAGGTCCAGCTGTGGTCATTCATGGAGTGGTGGCAAAGACAGACATGGTTCCAGC TCTGTAGAACTGAGAGAAAGAATAAACAAGTCACACATTAGCCCTTCTAGGGAATCTGGG GAGGAGTATGAATCTGGATCTGGATCAAACAGTTGGGAAAGGAAAGGTCATGGTGGTCTG TCATGTGGATTGGAGACTAGTGGGCATGAATCAAACTCTACTCAGTCAAGAATTAGAGAA CAAAAGCTTGGGTCTAGCTGTTCAGGTTCAGGAGACAGTGGGAGGCGAAGTCATGCATGT GGTTATAGCAATTCAAGTGGGTGTGGAAGGCCACAAAATGCTTCAAGTTCTTGTCAGTCA CATAGATTTGGAGGGCAAGGAAATCAATTTAGCTATATTCAGTCAGGCTGTCAGTCAGGA ATTAAGGGAGGACAAGGCCATGGCTGTGTCTCAGGAGGTCAGCCCTCTGGATGTGGTCAA CCTGAGTCTAACCCCTGTAGTCAGTCCTATAGTCAGAGAGGATATGGAGCTAGAGAAAAT GGTCAACCACAGAACTGTGGAGGACAATGGAGAACAGGCTCAAGTCAGTCCTCTTGCTGT GGACAATATGGGTCTGGAGGTAGCCAGTCTTGTAGTAATGGTCAACATGAATATGGTTCC TGTGGCCGCTTTTCAAACTCTTCTAGTTCAAATGAATTTTCCAAATGTGATCAATATGGG TCTGGTTCAAGTCAGTCTACTAGCTTTGAACAACATGGAACAGGCTTGAGTCAGTCCTCT GGGTTCGAACAACATGTATGTGGCTCAGGTCAAACTTGTGGCCAGCATGAGTCTACATCA AGTCAATCCTTGGGCTATGACCAGCATGGGTCTAGCTCAGGTAAGACATCTGGCTTTGGA CAACATGGGTCTGGCTCAGGTCAGTCCTCTGGCTTTGGACAATGTGGGTCAGGCTCAGGT CAGTCCTCTGGCTTTGGACAGCATGGGTCTGTCTCAGGACAATCCTCTGGTTTTGGACAG CATGGGTCTGTCTCAGGACAATCCTCTGGTTTTGGACAACATGAGTCTAGATCACGTCAG TCTAGCTATGGCCAACATGGTTCTGGCTCAAGTCAATCATCTGGCTATGGCCAATATGGG TCTAGAGAGACATCTGGCTTTGGACAACATGGGTTGGGCTCAGGTCAATCCACTGGCTTT GGCCAATATGGATCGGGCTCAGGTCAGTCCTCTGGCTTTGGACAACATGGGTCTGGCTCA GGACAATCCTCTGGCTTTGGACAACATGAGTCTAGATCAGGTCAGTCTAGTTATGGCCAA CACAGTTCTGGCTCAAGTCAGTCATCTGGCTATGGCCAACATGGGTCTAGACAGACATCT GGCTTTGGACAACATGGGTCAGGCTCAAGTCAATCCACTGGCTTTGGCCAATATGGATCA GGCTCAGGTCAGTCCTCTGGCTTTGGACAACATGTTTCTGGCTCAGGACAATCCTCTGGT TTTGGACAACATGAGTCTAGATCAGGTCATTCTAGCTATGGCCAACATGGTTTTGGCTCA AGTCAATCATCTGGCTATGGTCAACATGGGTCAAGTTCAGGACAGACATCTGGATTTGGA CAACACGAGTTAAGCTCAGGTCAGTCTTCCAGCTTTGGCCAACATGGATCAGGCTCAGGT CAGTCCTCTGGCTTTGGACAACATGGGTCTGGCTCAGGACAATCCTCTGGCTTTGGACAA CATGAGTCTAGATCAGGTCAGTCTAGCTATGGCCAACACAGTTCTGGCTCAAGTCAGTCA TCTGGCTATGGCCAACATGGGTCTAGACAGACATCTGGCTTTGGACAACATGGGTCAGGC TCAAGTCAATCCACTGGCTTTGGCCAATATGGATCAGGCTCAGGTCAGTCCGCTGGCTTT GGACAACATGGGTCTGGCTCAGGACAATCCTCTGGCTTTGGACAGCATGAGTCTAGATCA CATCAGTCCAGCTATGGCCAACATGGTTCTGGCTCAAGTCAATCATCTGGCTATGGTCAA CATGGGTCAAGTTCGGGACAGACATCTGGCTTTGGACAACACAGGTCAAGCTCAGGTCAA TACTCTGGCTTTGGACAACATGGATCAGGCTCAGGTCAGTCCAGTGGCTTTGGACAACAT GGGACTGGCTCAGGACAATACTCTGGTTTTGGACAACATGAGTCTAGATCACATCAGTCT AGCTATGGCCAACATGGTTCTGGCTCAAGTCAGTCATCTGGCTATGGTCAACATGGGTCA AGTTCAGGACAGACTTTTGGATTTGGACAACACAGGTCAGGCTCAGGTCAATCCTCTGGC TTTGGCCAACATGGATCAGGCTCAGGTCAGTCCTCTGGCTTTGGACAACATGAGTCAGGC TCAGGAAAATCCTCTGGCTTTGGACAGCATGAGTCTAGATCAAGTCAGTCTAATTATGGC CAACATGGTTCTGGCTCAAGTCAGTCATCTGGCTATGGTCAACATGGGTCTAGTTCAGGA CAGACAACTGGCTTTGGACAACACAGGTCAAGCTCAGGCCAATACTCAGGCTTTGGACAA CATGGATCAGGCTCAGATCAGTCCTCTGGCTTTGGACAACATGGGACTGGTTCAGGACAA TCCTCTGGTTTTGGACAATATGAGTCTAGATCACGTCAGTCTAGCTATGGCCAACATGGT TCTGGCTCAAGTCAATCATCTGGCTATGGTCAACATGGGTCAAATTCAGGACAGACATCT GGATTTGGACAACACAGGCCAGGCTCAGGTCAGTCCTCTGGCTTTGGCCAATATGGATCG GGCTCAGGTCAGTCTTCTGGCTTTGGACAACATGGGTCAGGCACAGGTAAATCCTCTGGC TTTGCACAGCATGAGTACAGATCAGGTCAGTCTAGCTATGGCCAACATGGTACTGGCTCC AGTCAATCATCTGGCTGTGGCCAACATGAGTCTGGCTCAGGTCCAACCACAAGTTTTGGA CAGCATGTGTCTGGCTCAGACAATTTCTCTAGTTCTGGACAACATATATCTGACTCAGGT CAGTCCACTGGATTTGGCCAATATGGTTCAGGCTCAGGTCAATCAACTGGCTTGGGCCAG GGTGAATCTCAACAAGTAGAGTCAGGATCCACAGTTCATGGGAGACAGGAAACTACTCAT GGTCAGACAATAAATACCACTAGACATAGCCAGTCTGGTCAAGGACAATCCACACAGACA GGGTCCAGGGTAACTAGAAGACGAAGATCTAGCCAAAGTGAGAACAGTGACAGTGAAGTG CACTCAAAGGTCTCACACAGACATTCAGAACACATTCACACACAAGCTGGATCTCACTAC CCAAAGTCAGGATCCACAGTTCGCAGAAGACAAGGAACTACTCATGGACAGAGAGGAGAT ACCACTAGACATGGCCATTCTGGTCATGGACAGTCTACACAGACAGGTTCCAGAACATCT GGAAGACAGAGATTTAGCCACAGTGATGCCACTGACAGTGAAGTGCACTCAGGGGTCTCA CATAGACCACACTCACAAGAACAAACTCACAGCCAAGCTGGATCTCAACATGGAGAGTCA GAATCCACAGTTCATGAGAGACATGAAACTACTTATGGACAGACAGGAGAGGCCACTGGA CATGGCCACTCTGGTCATGGACAGTCCACACAGAGAGGGTCCAGGACAACTGGAAGAAGG GGATCTGGCCATAGTGAGTCCAGTGACAGTGAAGTGCACTCAGGGGGCTCACACAGACCA CAATCACAAGAACAAACTCATGGCCAAGCCGGATCTCAACATGGAGAGTCAGGATCCACA GTTCATGGGAGACACGGAACTACTCATGGACAGACAGGAGATACCACTAGACATGCCCAC TATCATCATGGAAAATCCACACAGAGAGGGTCCAGTACAACTGGAAGAAGGGGATCTGGC CACAGTGAGTCCAGTGACAGTGAAGTGCACTCAGGGGGCTCGCACACACATTCAGGACAC ACTCACGGCCAAAGTGGATCTCAACATGGAGAGTCAGAATCCATAATTCATGACAGACAC AGAATTACTCATGGACAGACAGGAGATACCACTAGACATTCCTACTCTGGTCATGAACAA ACCACACAGACAGGGTCCAGGACAACTGGAAGACAGAGAACTAGCCACAGTGAGTCCACT GACAGTGAAGTGCACTCAGGGGGCTCACACAGACCACACTCACGAGAACACACTTACGGC CAAGCCGGATCTCAACATGAAGAGCCAGAATTCACAGTTCATGAGAGACACGGAACTACT CATGGACAGATAGGAGATACCACTGGACATTCCCACTCTGGTCATGGACAGTCCACACAG AGAGGGTCCAGGACAACTGGAAGACAGAGATCTAGCCACAGTGAGTCCAGTGACAGTGAA GTGCACTCAGGGGTCTCACACACACATACAGGACACACTCATGGTCAAGCTGGATCTCAA CATGGACAGTCAGAATCCATAGTTCCTGAGAGACATGGAACTACTCATGGACAGACAGGA GATACCACTAGACATGCCCACTATCATCATGGATTAACCACACAGACAGGGTCCAGGACT ACTGGAAGAAGGGGATCTGGCCACAGTGAGTACAGTGACAGTGAAGGGTACTCAGGAGTC TCACATACACATTCAGGACACACTCATGGCCAAGCCAGATCTCAACATGGAGAGTCAGAA TCCATAGTTCATGAGAGACATGGAACTATACATGGACAGACAGGCGATACCACCAGACAT GCCCACTCTGGTCATGGACAGTCCACACAGACAGGGTCCAGGACCACTGGAAGAAGGTCA TCTGGCCACAGTGAGTACAGTGACAGTGAAGGGCACTCAGGGTTCTCACAAAGACCACAC TCACGAGGACACACTCACGGCCAGGCTGGATCTCAACATGGAGAGTCAGAATCCATAGTT GACGAGAGACATGGAACTACTCATGGACAGACAGGAGATACCAGTGGACATTCTCAATCT GGTCATGGACAGTCCACACAGTCAGGATCCAGTACAACTGGAAGAAGGAGATCTGGCCAC AGTGAGTCCAGTGACAGTGAAGTGCACTCAGGGGGCTCACATACACATTCAGGACACACA CACAGCCAAGCCAGGTCTCAACATGGAGAGTCAGAATCCACAGTTCACAAGAGACACCAA ACTACTCATGGACAGACAGGAGATACCACTGAACATGGCCACCCTAGTCATGGACAAACC ATACAGACAGGGTCCAGGACAACTGGAAGAAGGGGATCTGGCCACAGTGAGTACAGTGAC AGTGAAGGGCCCTCAGGGGTCTCACACACACATTCAGGACACACTCACGGTCAAGCTGGA TCTCACTATCCAGAGTCAGGATCCTCAGTTCATGAGAGACACGGAACTACTCATGGACAA ACAGCAGATACCACTAGACATGGCCACTCTGGTCATGGACAGTCCACACAGAGAGGGTCC AGGACAACTGGAAGAAGGGCATCTGGCCACAGTGAGTACAGTGACAGTGAAGGGCACTCA GGGGTCTCACACACACATTCAGGACACGCTCATGGCCAAGCCGGATCTCAACATGGAGAG TCAGGATCCTCAGTTCATGAGAGACACGGAACTACTCATGGACAGACAGGAGATACCACT AGACATGCTCACTCTGGTCATGGACAGTCCACACAGAGAGGGTCAAGGACAGCTGGAAGA AGGGGATCTGGCCACAGTGAGTCCAGTGACAGTGAAGTGCACTCAGGGGTCTCACACACA CATTCAGGACACACTTATGGCCAAGCCAGATCTCAACATGGAGAGTCAGGATCTGCCATT CACGGGAGACAGGGAACTATACATGGACAGACAGGAGATACCACTAGACATGGCCAGTCT GGTCATGGACAGTCCACACAGACAGGTTCCAGGACAACTGGAAGACAAAGATCTAGTCAC AGTGAGTCCAGTGATAGTGAAGTGCACTCAGAGGCCTCACCCACACATTCAGGACACACT CACAGCCAAGCCGGATCTCGACATGGACAGTCAGGATCCTCAGGTCATGGGAGACAGGGA ACTACTCATGGACAGACAGGAGATACCACTAGACATGCCCACTATGGTTATGGACAATCC ACACAGAGAGGGTCCAGGACAACTGGAAGAAGGGGATCTGGCCACAGTGAGTCCAGTGAC AGTGAAGTGCACTCATGGGGCTCACACACACATTCAGGACACATTCAGGGCCAAGCTGGA TCTCAACAAAGACAGCCAGGATCCACAGTTCATGGGAGACTGGAAACTACTCATGGACAG ACAGGAGATACCACTAGACATGGCCATTCTGGTTATGGACAATCCACACAGACAGGTTCC AGATCTAGTAGAGCAAGTCATTTTCAGTCACATAGTAGTGAAAGGCAAAGGCATGGATCA AGTCAGGTTTGGAAACATGGCAGCTATGGACCTGCAGAATATGACTATGGGCACACTGGG TATGGGCCTTCTGGTGGCAGCAGAAAAAGCATCAGTAATTCTCACCTTTCATGGTCAACA GACAGCACTGCAAACAAGCAACTGTCTAGACATTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_001014342 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001014342.1, NP_001014364.1 |
| RefSeq Size | 9147 bp |
| RefSeq ORF | 7176 bp |
| Locus ID | 388698 |
| UniProt ID | Q5D862 |
| Gene Summary | The filaggrin-like protein encoded by this gene is upregulated by calcium, proteolyzed by calpain 1, and is involved in epithelial homeostasis. The encoded protein is required for proper cornification in skin, with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact, in addition to providing a physical barrier, C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa and E. coli. [provided by RefSeq, Jul 2020] |
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