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Dynamin 1 (DNM1) (NM_001005336) Human Untagged Clone
CAT＃: SC300909
DNM1 (untagged)-Human dynamin 1 (DNM1), transcript variant 2
CNY 9,360.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DEE31; DNM; EIEE31 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001005336 edited
AGTCGGGGCGCGCGGCTGCAGCGGCGGAGCCGGAGTCGGAGCCGGGAGCGCTAGCGGCAG CCGGATCGCAGCCTGCGGGGCCAGCCGCAGCCATGGGCAACCGCGGCATGGAAGATCTCA TCCCGCTGGTCAACCGGCTGCAAGACGCCTTCTCTGCCATCGGCCAGAACGCGGACCTCG ACCTGCCGCAGATCGCTGTGGTGGGCGGCCAGAGCGCCGGCAAGAGCTCGGTGCTCGAGA ATTTCGTAGGCAGGGACTTCTTGCCTCGAGGATCTGGCATTGTCACCCGACGTCCCCTGG TCTTGCAGCTGGTCAATGCAACCACAGAATATGCCGAGTTCCTGCACTGCAAGGGAAAGA AATTCACCGACTTCGAGGAGGTGCGCCTTGAGATCGAGGCCGAGACCGACAGGGTCACCG GCACCAAC:AAGGGCATCTCGCCGGTGCCTATC:AACCTCCGCGTCTACTCGCCGCACGT GCTGAACCTGACCCTGGTGGACCTGCCCGGAATGACCAAGGTCCCGGTGGGGGACCAACC TCCCGACATCGAGTTCCAGATCCGAGACATGCTTATGCAGTTTGTCACCAAGGAGAACTG CCTCATCCTGGCCGTGTCCCCCGCCAACTCTGACCTGGCCAATTCTGACGCCCTCGAGGT CGCCAAGGAGGTGGACCCCCAGGGCCAGCGCACCATCGGGGTCATCACCAAGCTGGACCT GATGGACGAGGGCACAGATGCCCGTGATGTGCTGGAGAACAAGCTGCTCCCCCTGCGCAG AGGCTACATTGGAGTGGTGAACCGGAGCCAGAAGGACATTGATGGCAAGAAGGACATTAC CGCCGCCTTGGCTGCTGAACGAAAGTTCTTCCTCTCCCATCCATCTTATCGCCACTTGGC TGACCGTATGGGCACGCCCTACCTGCAGAAGGTCCTCAATCAGCAACTGACGGACCACAT CCGGGACACACTGCCGGGGCTGCGGAACAAGCTGCAGAGCCAGCTACTGTCCATTGAGAA GGAGGTGGAGGAATACAAGAACTTCCGCCCTGATGACCCAGCTCGCAAGACCAAGGCCCT GCTGCAGATGGTCCAGCAGTTCGCCGTAGACTTTGAGAAGCGCATTGAGGGCTCAGGAGA TCAGATCGACACCTACGAACTGTCAGGGGGAGCCCGCATTAACCGAATCTTCCACGAGCG CTTCCCTTTCGAGCTGGTCAAGATGGAGTTTGATGAGAAGGAACTCCGAAGGGAGATCAG CTATGCTATCAAGAATATCCATGGCATTAGAACGGGGCTGTTTACCCCAGACATGGCCTT TGAGACCATTGTGAAAAAGCAGGTGAAGAAGATCCGAGAACCGTGTCTCAAGTGTGTGGA CATGGTTATCTCGGAGCTAATCAGCACCGTTAGACAGTGCACCAAGAAGCTCCAGCAGTA CCCGCGGCTACGGGAGGAGATGGAGCGCATCGTGACCACCCACATCCGGGAGCGCGAGGG CCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAA CCATGAGGACTTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAA GAAGACTTCAGGGAACCAGGATGAGATTCTGGTCATCCGCAAGGGCTGGCTGACTATCAA TAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAA TCTGTCCTGGTACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAA CCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATGTCGAGCAAGCATATCTTTGCCCTCTT TAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGAC ACAGGAGGAGGTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCG TGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAGGAGAATGGCTCCGACAGCTTCATGCA TTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATA CATGGCCATTGTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCAT GATTAACAATACCAAGGAGTTCATCTTCTCGGAGCTGCTGGCCAACCTGTACTCGTGTGG GGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCT GCGCATGTACCACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCAC CGTCAGCACGCCCATGCCCCCGCCCGTGGACGACTCCTGGCTGCAGGTGCAGAGCGTACC GGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCC CCCAGCCCGGCCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCAT GGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGGGCTTCCCCTGACCCTTTCGGCCCTCC CCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGAATCACTATCAG TGACCCCTGAGGAGCGTCAGCCATGCCGATCGGGTCAGGCAAGTCCATCCCGTCCTGAGA GCCCCAGGCCCCCCTTCGACCTCTAAACAGATCCCTCCTCTTCTCGGAGACCTCCCTTTC CAAGCCTGCCTGGACGGCTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAG CCCCCTTCATCTGTGACTTAATCTGTTGTAGTGGTGAGCTGATACATTCAGGTGTGACCG TTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCCCTTGCCCTGTTCTATAAATATCTATA AATACTCATATATATACACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAAT CAGTCACTGTGCTATCCTTGTGGAGTCTTGTGGCCCAACTACCAGAGAACGCTGTCCCCC GACATCCCACTCCAAAGTGTGCCACCTCCAGTGAGCCTCCTTGTCATGCCCGGCCTGTGG ACAGCCAGCCCCCGCCATCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAG CCGTGTGGCCTGACAGTTTCTACCAGTCCTGCTGTCCCTCGGCTGAGAATAAAACCCATT TCTGGATGAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001005336 |
| Insert Size | 3200 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to contain 3 SNPs compared with NM_001005336.1. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001005336.1, NP_001005336.1 |
| RefSeq Size | 3253 bp |
| RefSeq ORF | 2556 bp |
| Locus ID | 1759 |
| UniProt ID | Q05193 |
| Protein Families | Druggable Genome |
| Protein Pathways | Endocytosis, Fc gamma R-mediated phagocytosis |
| Gene Summary | This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) includes an alternate exon in the 3' coding region that results in a frameshift and an early stop codon, compared to variant 1. The resulting isoform (2), also known as internal form 2 and the short C-terminal form, is shorter and has a distinct C-terminus, compared to isoform 1. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206284 | DNM1 (Myc-DDK-tagged)-Human dynamin 1 (DNM1), transcript variant 2 |
CNY 9,344.00 |
|
| RC206284L1 | Lenti ORF clone of Human dynamin 1 (DNM1), transcript variant 2, Myc-DDK-tagged |
CNY 11,744.00 |
|
| RC206284L2 | Lenti ORF clone of Human dynamin 1 (DNM1), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC206284L3 | Lenti ORF clone of Human dynamin 1 (DNM1), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206284L4 | Lenti ORF clone of Human dynamin 1 (DNM1), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG206284 | DNM1 (tGFP-tagged) - Human dynamin 1 (DNM1), transcript variant 2 |
CNY 4,370.00 |
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