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FGFR4 (NM_022963) Human Untagged Clone
CAT＃: SC128287
FGFR4 (untagged)-Human fibroblast growth factor receptor 4 (FGFR4), transcript variant 2
CNY 5,592.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD334; JTK2; TKF |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_022963 edited
GAATTCGGCACGAGGCCGAGGAGCGCTCGGGCTGTCTGCGGACCCTGCCGCGTGCAGGGG TCGCGGCCGGCTGGAGCTGGGAGTGAGGCGGCGGAGGAGCCAGGTGAGGAGGAGCCAGGA AGGCAGTTGGTGGGAAGTCCAGCTTGGGTCCCTGAGAGCTGTGAGAAGGAGATGCGGCTG CTGCTGGCCCTGTTGGGGGTCCTGCTGAGTGTGCCTGGGCCTCCAGTCTTGTCCCTGGAG GCCTCTGAGGAAGTGGAGCTTGAGCCCTGCCTGGCTCCCAGCCTGGAGCAGCAAGAGCAG GAGCTGACAGTAGCCCTTGGGCAGCCTGTGCGGCTGTGCTGTGGGCGGGCTGAGCGTGGT GGCCACTGGTACAAGGAGGGCAGTCGCCTGGCACCTGCTGGCCGTGTACGGGGCTGGAGG GGCCGCCTAGAGATTGCCAGCTTCCTACCTGAGGATGCTGGCCGCTACCTCTGCCTGGCA CGAGGCTCCATGATCGTCCTGCAGAATCTCACCTTGATTACAGGTGACTCCTTGACCTCC AGCAACGATGATGAGGACCCCAAGTCCCATAGGGACCTCTCGAATAGGCACAGTTACCCC CAGCAAGCACCCTACTGGACACACCCCCAGCGCATGGAGAAGAAACTGCATGCAGTACCT GCGGGGAACACCGTCAAGTTCCGCTGTCCAGCTGCAGGCAACCCCACGCCCACCATCCGC TGGCTTAAGGATGGACAGGCCTTTCATGGGGAGAACCGCATTGGAGGCATTCGGCTGCGC CATCAGCACTGGAGTCTCGTGATGGAGAGCGTGGTGCCCTCGGACCGCGGCACATACACC TGCCTGGTAGAGAACGCTGTGGGCAGCATCCGTTATAACTACCTGCTAGATGTGCTGGAG CGGTCCCCGCACCGGCCCATCCTGCAGGCCGGGCTCCCGGCCAACACCACAGCCGTGGTG GGCAGCGACGTGGAGCTGCTGTGCAAGGTGTACAGCGATGCCCAGCCCCACATCCAGTGG CTGAAGCACATCGTCATCAACGGCAGCAGCTTCGGAGCCGACGGTTTCCCCTATGTGCAA GTCCTAAAGACTGCAGACATCAATAGCTCAGAGGTGGAGGTCCTGTACCTGCGGAACGTG TCAGCCGAGGACGCAGGCGAGTACACCTGCCTCGCAGGCAATTCCATCGGCCTCTCCTAC CAGTCTGCCTGGCTCACGGTGCTGCCAGGTACTGGGCGCATCCCCCACCTCACATGTGAC AGCCTGACTCCAGCAGGCAGAACCAAGTCTCCCACTTTGCAGTTCTCCCTGGAGTCAGGC TCTTCCGGCAAGTCAAGCTCATCCCTGGTACGAGGCGTGCGTCTCTCCTCCAGCGGCCCC GCCTTGCTCGCCGGCCTCGTGAGTCTAGATCTACCTCTCGACCCACTATGGGAGTTCCCC CGGGACAGGCTGGTGCTTGGGAAGCCCCTAGGCGAGGGCTGCTTTGGCCAGGTAGTACGT GCAGAGGCCTTTGGCATGGACCCTGCCCGGCCTGACCAAGCCAGCACTGTGGCCGTCAAG ATGCTCAAAGACAACGCCTCTGACAAGGACCTGGCCGACCTGGTCTCGGAGATGGAGGTG ATGAAGCTGATCGGCCGACACAAGAACATCATCAACCTGCTTGGTGTCTGCACCCAGGAA GGGCCCCTGTACGTGATCGTGGAGTGCGCCGCCAAGGGAAACCTGCGGGAGTTCCTGCGG GCCCGGCGCCCCCCAGGCCCCGACCTCAGCCCCGACGGTCCTCGGAGCAGTGAGGGGCCG CTCTCCTTCCCAGTCCTGGTCTCCTGCGCCTACCAGGTGGCCCGAGGCATGCAGTATCTG GAGTCCCGGAAGTGTATCCACCGGGACCTGGCTGCCCGCAATGTGCTGGTGACTGAGGAC AATGTGATGAAGATTGCTGACTTTGGGCTGGCCCGCGGCGTCCACCACATTGACTACTAT AAGAAAACCAGCAACGGCCGCCTGCCTGTGAAGTGGATGGCGCCCGAGGCCTTGTTTGAC CGGGTGTACACACACCAGAGTGACGTGTGGTCTTTTGGGATCCTGCTATGGGAGATCTTC ACCCTCGGGGGCTCCCCGTATCCTGGCATCCCGGTGGAGGAGCTGTTCTCGCTGCTGCGG GAGGGACATCGGATGGACCGACCCCCACACTGCCCCCCAGAGCTGTACGGGCTGATGCGT GAGTGCTGGCACGCAGCGCCCTCCCAGAGGCCTACCTTCAAGCAGCTGGTGGAGGCGCTG GACAAGGTCCTGCTGGCCGTCTCTGAGGAGTACCTCGACCTCCGCCTGACCTTCGGACCC TATTCCCCCTCTGGTGGGGACGCCAGCAGCACCTGCTCCTCCAGCGATTCTGTCTTCAGC CACGACCCCCTGCCATTGGGATCCAGCTCCTTCCCCTTCGGGTCTGGGGTGCAGACATGA >OriGene 5' read for NM_022963 unedited
GTGGGATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGGCACGAGGCCGAGGAGCG CTCGGGCTGTCTGCGGACCCTGCCGCGTGCAGGGGTCGCGGCCGGCTGGAGCTGGGAGTG AGGCGGCGGAGGAGCCAGGTGAGGAGGAGCCAGGAAGGCAGTTGGTGGGAAGTCCAGCTT GGGTCCCTGAGAGCTGTGAGAAGGAGATGCGGCTGCTGCTGGCCCTGTTGGGGGTCCTGC TGAGTGTGCCTGGGCCTCCAGTCTTGTCCCTGGAGGCCTCTGAGGAAGTGGAGCTTGAGC CCTGCCTGGCTCCCAGCCTGGAGCAGCAAGAGCAGGAGCTGACAGTAGCCCTTGGGCAGC CTGTGCGGCTGTGCTGTGGGCGGGCTGAGCGTGGTGGCCACTGGTACAAGGAGGGCAGTC GCCTGGCACCTGCTGGCCGTGTACGGGGCTGGAGGGGCCGCCTAGAGATTGCCAGCTTCC TACCTGAGGATGCTGGCCGCTACCTCTGCCTGGCACGAGGCTCCATGATCGTCCTGCAGA ATCTCACCTTGATTACAGGTGACTCCTTGACCTCCAGCAACGATGATGAGGACCCCAAGT CCCATAGGGACCTCTCGAATAGGCACAGTTACCCCCAGCAAGCACCCTACTGGACACACC CCCAGCGCATGGAGAAGAAACTGCATGCAGTACCTGCGGGGAACACCGTCAAGTTCCGCT GTCCAGCTGCAGGCAACCCCACGCCCACCATCCGCTGGCTTAAAGATGGACAGGCCTTTC ATGGGGAGAACCGCATTGGAGGCATTCGCTGCGCCATCAGCACTGGAGTCTCGTGATGGA GAGCGTGTGCCCTCGGACCGCGCACATACACCTGCCTGGTAGAGAACGCTGTGGGCAGCA TCCGTTATAACTACCTGCTAGATGTGCTGGAGCGGTCCCCGCACCGG >OriGene 3' read for NM_022963 unedited
GGGTGTGTATAAAACGCCTTTGCTCCTGTTTTGCGGCAGGCTTCCAGCTTCTCTGGGCTC AGGGGCCAATGCTCCCGTCAAGACGCTGGGGCAGCAGCAGCAGGGGGAGGTGTGGGGAAA GGGGGTTCAGAGGCCCAGAACCTCCTGCTGGTATTGGGAGGCAGGAGGTTTAGCATAGCA GCTCTCCAGCCAGGCTCAGCCAAACCCGGGATGGGGACTAAGCGCCAAGGTCCAAGAAGC CGAGCAGAACCCTGACATTTGGGCCATCAGGACACAGGCACGGCAGCTCCAAGGGCAAGG GCACGGCCCTTGGACACGGCACAGCAACTCTGGGCCAGGGGCCCCATGCTATCAAGGTCG AGCACTGTGTCAGGCTGTGGCTGAGCCCCAAGGCCCAAGGCCACCAGCCTATGTGCCTGC ACAGCCTTGAGCCTTGCTCATGTCTGCACCCCAGACCCGAAGGGGAAGGAGCTGGATCCC AATGGCAGGGGGTCGTGGCTGAAGACAGAATCGCTGGAGGAGCAGGTGCTGCTGGCGTCC CCACCAGAGGGGGAATAGGGTCCGAAGGTCAGGCGGAGGTCGAGGTACTCCTCAGAGACG GCCAGCAGGACCTTGTCCAGCGCCTCCACCAGCTGCTTGAAGGTAGGCCTCTGGGAGGGC GCTGCGTGCCAGCACTCACGCATCAGCCCCGTACAGCTCTGGGGGGCAGTGTGGGGGTCG GTCCATCCGATGTCCCTCCCGCAGCAGCGAGAACAGCTCCTCCACCGGGATGCCAGGATA CGGGGAGCCCCCGAGGGTGAAGATCTCCCATAGCAGGATCCCAAAAGACCACCACGTCAC TCTGGTGTGTGTACACCGGTCAAACAAGGCCTCGGGCGCATCCACTTCACAGGCAGCGCC GTGCTGGTTTTCCTAATAGTAGTCAATGGTGGTGGACGCCCGCGGGGCCAGCCCAAAGTC AGCAAATCC |
| Restriction Sites | Please inquire |
| ACCN | NM_022963 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_022963.2, NP_075252.2 |
| RefSeq Size | 2807 bp |
| RefSeq ORF | 2289 bp |
| Locus ID | 2264 |
| UniProt ID | P22455 |
| Domains | pkinase, TyrKc, S_TKc, ig, IGc2, IG |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Endocytosis, MAPK signaling pathway, Regulation of actin cytoskeleton |
| Gene Summary | The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017] Transcript Variant: This variant (2) lacks an internal exon but has an alternate segment in the central coding region, compared to variant 1. The resulting isoform (2) has a distinct and shorter internal segment, compared to isoform 1, and it is missing the transmembrane region, suggesting a soluble rather than membrane-bound receptor. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219813 | FGFR4 (Myc-DDK-tagged)-Human fibroblast growth factor receptor 4 (FGFR4), transcript variant 2 |
CNY 5,584.00 |
|
| RC219813L3 | Lenti ORF clone of Human fibroblast growth factor receptor 4 (FGFR4), transcript variant 2, Myc-DDK-tagged |
CNY 9,980.00 |
|
| RC219813L4 | Lenti ORF clone of Human fibroblast growth factor receptor 4 (FGFR4), transcript variant 2, mGFP tagged |
CNY 9,980.00 |
|
| RG219813 | FGFR4 (tGFP-tagged) - Human fibroblast growth factor receptor 4 (FGFR4), transcript variant 2 |
CNY 8,930.00 |
