ING3 (NM_019071) Human Untagged Clone
CAT＃: SC128111
ING3 (untagged)-Human inhibitor of growth family, member 3 (ING3), transcript variant 1
CNY 3656.00
CNY 6750.00
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Eaf4; ING2; MEAF4; p47ING3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_019071 edited
TACCATGTTGTACCTAGAAGACTATCTGGAAATGATTGAGCAGCTTCCTATGGATCTGCG GGACCGCTTCACGGAAATGCGCGAGATGGACCTGCAGGTGCAGAATGCAATGGATCAACT AGAACAAAGAGTCAGTGAATTCTTTATGAATGCAAAGAAAAATAAACCTGAGTGGAGGGA AGAGCAAATGGCATCCATCAAAAAAGACTACTATAAAGCTTTGGAAGATGCAGATGAGAA GGTTCAGTTGGCAAACCAGATATATGACTTGGTAGATCGACACTTGAGAAAGCTGGATCA GGAACTGGCTAAGTTTAAAATGGAGCTGGAAGCTGATAATGCTGGAATTACAGAAATATT AGAGAGGCGATCTTTGGAATTAGACACTCCTTCACAGCCAGTGAACAATCACCATGCTCA TTCACATACTCCAGTGGAAAAAAGGAAATATAATCCAACTTCTCACCATACGACAACAGA TCATATTCCTGAAAAGAAATTTAAATCTGAAGCTCTTCTATCCACCCTTACGTCAGATGC CTCTAAGGAAAATACACTAGGTTGTCGAAATAATAATTCCACAGCCTCTTCTAACAATGC CTACAATGTGAATTCCTCCCAACCTCTGGGATCCTATAACATTGGCTCGTTATCTTCAGG AACTGGTGCAGGGGCAATTACCATGGCAGCTGCTCAAGCAGTTCAGGCTACAGCTCAGAT GAAGGAGGGACGAAGAACATCAAGTTTAAAAGCCAGTTATGAAGCATTTAAGAATAATGA CTTTCAGTTGGGAAAAGAATTTTCAATGGCCAGGGAAACAGTTGGCTATTCATCATCTTC GGCACTTATGACAACATTAACACAGAATGCCAGTTCATCAGCAGCCGACTCACGGAGTGG TCGAAAGAGCAAAAACAACAACAAGTCTTCAAGCCAGCAGTCATCATCTTCCTCCTCCTC TTCTTCCTTATCATCGTGTTCTTCATCATCAACTGTTGTACAAGAAATCTCTCAACAAAC AACTGTAGTGCCAGAATCTGATTCAAATAGTCAGGTTGATTGGACTTACGACCCAAATGA ACCTCGATACTGCATTTGTAATCAGGTATCTTATGGTGAGATGGTGGGATGTGATAACCA AGATTGCCCTATAGAATGGTTCCATTATGGCTGCGTTGGATTGACAGAGGCACCAAAAGG CAAATGGTACTGTCCACAGTGCACTGCTGCAATGAAGAGAAGAGGCAGCAGACACAAATA AAGGTGGTCCTTTTGTTTGATGAAGAAATAAACTTCAGCTGAAGATTTTATATAGGACTT TAAAAAGAAGAGAAGAGAAAGAAGAAACAATGCATTTCCAGGCAACCACTTAAAGGATTT >OriGene 5' read for NM_019071 unedited
GGAGTTCACAATTTGTATACGACTCACTATAGGCGGCCGCGNATTCAAATCTGGTACCAT GTTGTACCTAGAAGACTATCTGGAATGATTGAGCAGCTTCCTATGGATCTGCGGGACCGC TTCACGGAAATGCGCGAGATGGACCTGCAGGTGCAGAATGCAATGGATCAACTAGAACAA AGAGTCAGTGAATTCTTTATGAATGCAAAGAAAAATAAACCTGAGTGGAGGGAAGAGCAA ATGGCATCCATCAAAAAAGACTACTATAAAGCTTTGGAAGATGCAGATGAGAAGGTTCAG TTGGCAAACCAGATATATGACTTGGTAGATCGACACTTGAGAAAGCTGGATCAGGAACTG GCTAAGTTTAAAATGGAGCTGGAAGCTGATAATGCTGGAATTACAGAAATATTAGAGAGG CGATCTTTGGAATTAGACACTCCTTCACAGCCAGTGAACAATCACCATGCTCATTCACAT ACTCCAGTGGAAAAAAGGAAATATAATCCAACTTCTCACCATACGACAACAGATCATATT CCTGAAAAGAAATTTAAATCTGAAGCTCTTCTATCCACCCTTACGTCAGATGCCTCTAAG GAAAATACACNTANGTTGTCGAAATAATAATTCCACAGCCTCTTCTAACAATGCCTACAA TGTGAATTCCTCCCACCTCTGGGATCCTATAACATTGGCTCGTTATCTTCAGGAACTGGT GCAGGGGCAATTACCATGGCAGCTGTNCAAGCAGTTCAGGCTACAGCTCAGATGAAAGAG GNACGAAGAAACATCAAGTTAANAGCCAGTTATGAAGCATTTAAGATAATGACTTTCAGT TGGGAAAAGATTTTTCATGGCCAGGGAAACAGTTGGCTATTCATCATCTTCGCACTTATG ACACAT >OriGene 3' read for NM_019071 unedited
NNCCATGGAATGGCACTTCCAGGNCCAGGNANAGCACTGGGGNAGGGTCACAGGGATGCC ACCCGGGATCTGTTCAGGAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGAAATCCT TTAAGTGGTTGCCTGGAAATGCATTGTTTCTTCTTTCTCTTCTCTTCTTTTTAAAGTCCT ATATAAAATCTTCAGCTGAAGTTTATTTCTTCATCAAACAAAAGGACCACCTTTATTTGT GTCTGCTGCCTCTTCTCTTCATTGCAGCAGTGCACTGTGGACAGTACCATTTGCCTTTTG GTGCCTCTGTCAATCCAACGCAGCCATAATGGAACCATTCTATAGGGCAATCTTGGTTAT CACATCCCACCATCTCACCATAAGATACCTGATTACAAATGCAGTATCGAGGTTCATTTG GGTCGTAAGTCCAATCAACCTGACTATTTGAATCAGATTCTGGCACTACAGTTGTTTGTT GAGAGATTTCTTGTACAACAGTTGATGATGAAGAACACGATGATAAGGAAGAAGAGGAGG AGGAAGATGATGACTGCTGGCTTGAAGACTTGTTGTTGTTTTTGCTCTTTCGACCACTCC GTGAGTCGGCTGCTGATGAACTGGCATTCTGTGTTAATGTTGTCATAAGTGCCGAAGATG ATGAATAGCCAACTGTTTCCCTGGCCATTGAAAATTCTTTTCCCAACTGAAAGTCATTAT TCTTAAATGCTTCATAACTGGCTTTTAACCTTGATGTTCTTCGTCCCTCCTTCATCTGAG CTGTAGCCTGAACTGCTTGAGCAGCTGCCATGGTAATTGCCCCTGCACCAGTTCCTGAAG AAACGAGCCAATGTTATANGATCCCCANAGGTTGGGGAGGAATTCACATTGNTAGCA |
| Restriction Sites | Please inquire |
| ACCN | NM_019071 |
| Insert Size | 1400 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_019071.2, NP_061944.2 |
| RefSeq Size | 2221 bp |
| RefSeq ORF | 1257 bp |
| Locus ID | 54556 |
| UniProt ID | Q9NXR8 |
| Domains | PHD |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218424 | ING3 (Myc-DDK-tagged)-Human inhibitor of growth family, member 3 (ING3), transcript variant 1 |
CNY 3656.00 |
|
| RC218424L1 | Lenti ORF clone of Human inhibitor of growth family, member 3 (ING3), transcript variant 1, Myc-DDK-tagged |
CNY 6056.00 |
|
| RC218424L2 | Lenti ORF clone of Human inhibitor of growth family, member 3 (ING3), transcript variant 1, mGFP tagged |
CNY 6056.00 |
|
| RC218424L3 | Lenti ORF clone of Human inhibitor of growth family, member 3 (ING3), transcript variant 1, Myc-DDK-tagged |
CNY 6056.00 |
|
| RC218424L4 | Lenti ORF clone of Human inhibitor of growth family, member 3 (ING3), transcript variant 1, mGFP tagged |
CNY 5890.00 |
|
| RG218424 | ING3 (tGFP-tagged) - Human inhibitor of growth family, member 3 (ING3), transcript variant 1 |
CNY 5256.00 |
