TMEM106A (NM_145041) Human Untagged Clone
CAT＃: SC127584
TMEM106A (untagged)-Human transmembrane protein 106A (TMEM106A)
CNY 2400.00
CNY 2950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_145041, the custom clone sequence may differ by one or more nucleotides
ATGGGTAAGACGTTTTCCCAGCTGGGCTCTTGGCGGGAGGATGAGAACAAGTCAATCCTGTCCTCCAAAC CAGCCATTGGCAGCAAGGCTGTCAACTACTCCAGCACCGGTAGCAGCAAGTCTTTTTGTTCCTGTGTGCC TTGTGAAGGAACTGCTGATGCCAGCTTCGTGACTTGTCCCACCTGCCAGGGCAGTGGCAAGATTCCCCAA GAGCTGGAGAAGCAGTTGGTGGCTCTCATTCCCTATGGGGACCAGAGGCTGAAGCCCAAGCACACGAAGC TCTTTGTGTTCCTGGCCGTGCTCATCTGCCTGGTGACCTCCTCCTTCATCGTCTTTTTCCTGTTTCCCCG GTCCGTCATTGTGCAGCCTGCAGGCCTCAACTCCTCCACAGTGGCCTTTGATGAGGCTGATATCTACCTC AACATAACGAATATCTTAAACATCTCCAATGGCAACTACTACCCCATTATGGTGACACAGCTGACCCTCG AGGTTCTGCACCTGTCCCTCGTGGTGGGGCAGGTTTCCAACAACCTTCTCCTACACATTGGCCCTTTGGC CAGTGAACAGATGTTTTACGCAGTAGCTACCAAGATACGGGATGAAAACACATACAAAATCTGTACCTGG CTGGAAATCAAAGTCCACCATGTGCTTTTGCACATCCAGGGCACCCTGACCTGTTCATACCTGAGCCATT CAGAGCAGCTGGTCTTTCAGAGCTATGAATATGTGGACTGCCGAGGAAACGCATCTGTGCCCCACCAGCT GACCCCTCACCCACCATGA >OriGene 5' read for NM_145041 unedited
CATATTTTGTAATACGACTCACTATAGGCGGCACGCGATTCGGCACGAGGTTTCTGTCGC TGCAGTCGTCCGCGGTGCGGCACATTCGTTCCCCTAGGACTCCGGCCGGTTGCCGGCCCC AGGCGGTGCTTCTCCCCACCACCGCCCAGCTCAGCTCAGCCCAGCCCAGCCCACTCTGCC CTTAGAGGCCCTTCTCCCCAAAGACGCACTCCAGAAGTCTCGCCCTCGTGCGGCTGAGGA GCCTGGGATCCCAGACCTGAACAAGTGAAACCCCCGCCCCTGAAGAATGGGTAAGACGTT TTCCCAGCTGGGCTCTTGGCGGGAGGATGAGAACAAGTCAATCCTGTCCTCCAAACCAGC CATTGGCAGCAAGGCTGTCAACTACTCCAGCACCGGTAGCAGCAAGTCTTTTTGTTCCTG TGTGCCTTGTGAAAGAACTGCTGATGCCAGCTTCGTGACTTGTCCCACCTGCCAGGGCAG TGGCAAGATTCCCCAAGAGCTGGAGAAGCAGTTGGTGGCTCTCATTCCCTATGGGGACCA GAGGCTGAAGCCCAAGCACACGAAGCTCTTTGTGTTCCTGGCCGTGCTCATCTGCCTGGT GACCTCCTCCTTCATCGTCTTTTTCCTGTTTCCCCGGTCCGTCATTGTGCAGCCTGCANG CCTCAACTCCTCCACAGTGGCCTTTGATGAAGCTGATATCTACCTCAACATAACGAATAT CTTAAACATCTNCAATGGCAACTACTACCCCATTATGGTGACACAGCTGACCCCTCGAGG TCTGCACCTGTCCNTCGTGGTGGGAGCAGGTTTCCAACAAACCTCTNCTAACATTGGCCC TTTNGCCAGTGAACAGATGTNTACGCAGTAGCTACCAGATACGGGATGAAACACTACAAA TCTGTACTGGCTGGAATCAAGTNCACATGTGCTTTGCACATCAGGCACCNTGACTGTNAT ACTGAGCATCAAAGCACTGGCTTCAACTANGATATGTGACTGCGAGAACACATCGC >OriGene 3' read for NM_145041 unedited
GCACTGAGGGCCAGGGGTCACAGGGGATGCCACCCGGGATCTGTTCAGGAAACAGCTATG ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTATTTTTTTTTTTAAACGGGGTCTTGCTAA TGTTGCTGCTCATGTTAAACTTGAATTCCTGGGCTCTAGAGATCCTCTCACCTCAGCTTC CTGAGTAGCTGGGACTACAGGTATATACCACTGCACCCAGATTGTAAGACCAAGCCACCT TTAATGAACAAATATCCTTCCTGTTCTGCTAAAGTACAGAAACTATTTCTACTAGGAGCC AGTGGGAACCTAGGGGTTATCTGGAGCTTATCTCCAGCTAAGTGACAGGAAAGGGAGGGT CTAGACCAGTCCCTGCTGATGTGCTGCTCCACATTGTCAAAGCCCAAGGAGAGATGAGGC CTCTGGGACCAGACAGGGCCCTGGTGCTAAGGTGGTGGTGGAACAGAACCCAGCACCCTT CAGCTGGATACTGATAGCTTCATCTCCTGAAGGCTTTCAAATGACAGCAGCTGGACCCCA CCGTTTTACCTACCTGTGTCCCCTCACATGCGCTTANGATGTGGACTTAGAGGCTCTCCT TTATAAATATCTTATCCATTGATTCTGTCTTTGGACTTGTTTTTCCTGTGCAGGCCCCGC AAATTGCCAGGTGCCTTCTTTCCCCTCCTCTATATTTTGGGCTCGGGCTATTAAAAGGAT AAGTAAAACTACTTTTAAAGAAAAGGAGAACCCTTTACCTTTGGAAACCACACTTTGGTT TTCTTGGGACCCGGGGGCACGATGCTTTACCCACTAAAGGGGCAGAGAGTGTTAAAGGCC CCCTGGGGCATAACTTTCTTACACAGAGGGGTGGCCTGCCCTCTTTTCCCGGAAGAAGAG CAATCATATGCCTTATTNCCACGGGGCCAAGGCCAATACGCCCCCAGATAAGATCTCTTT TTTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_145041 |
| Insert Size | 3100 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_145041.1, NP_659478.1 |
| RefSeq Size | 2795 bp |
| RefSeq ORF | 789 bp |
| Locus ID | 113277 |
| UniProt ID | Q96A25 |
| Protein Families | Transmembrane |
| Gene Summary | Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway. Upon activation, upregulates the expression of CD80, CD86, CD69 and MHC II on macrophages, and induces the release of pro-inflammatory cytokines such as TNF, IL1B, IL6, CCL2 and nitric oxide (By similarity). May play a role in inhibition of proliferation and migration (PubMed:30456879, PubMed:29131025).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223763 | TMEM106A (Myc-DDK-tagged)-Human transmembrane protein 106A (TMEM106A) |
CNY 2400.00 |
|
| RC223763L1 | Lenti-ORF clone of TMEM106A (Myc-DDK-tagged)-Human transmembrane protein 106A (TMEM106A) |
CNY 4800.00 |
|
| RC223763L2 | Lenti-ORF clone of TMEM106A (mGFP-tagged)-Human transmembrane protein 106A (TMEM106A) |
CNY 5890.00 |
|
| RC223763L3 | Lenti-ORF clone of TMEM106A (Myc-DDK-tagged)-Human transmembrane protein 106A (TMEM106A) |
CNY 5890.00 |
|
| RC223763L4 | Lenti-ORF clone of TMEM106A (mGFP-tagged)-Human transmembrane protein 106A (TMEM106A) |
CNY 5890.00 |
|
| RG223763 | TMEM106A (tGFP-tagged) - Human transmembrane protein 106A (TMEM106A) |
CNY 4370.00 |
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