LIN7C (NM_018362) Human Untagged Clone
CAT＃: SC127489
LIN7C (untagged)-Human lin-7 homolog C (C. elegans) (LIN7C)
CNY 2400.00
CNY 2950.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LIN-7-C; LIN-7C; MALS-3; MALS3; VELI3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_018362, the custom clone sequence may differ by one or more nucleotides
ATGGCGGCGCTAGGGGAACCCGTGCGGCTGGAGAGAGATATTTGTAGAGCAATTGAATTATTGGAAAAAC TACAAAGGAGTGGAGAAGTACCACCACAGAAACTTCAGGCTTTGCAAAGAGTCCTTCAAAGTGAATTCTG CAATGCTGTGAGAGAGGTATATGAACATGTCTATGAGACTGTGGACATCAGTAGCAGTCCTGAAGTGAGA GCGAACGCTACTGCAAAGGCTACTGTTGCTGCATTTGCTGCCAGTGAAGGACATTCTCATCCTCGAGTTG TTGAGCTACCAAAAACAGAAGAGGGCCTTGGATTCAATATTATGGGAGGCAAAGAACAAAACTCTCCAAT CTATATATCCCGAATAATTCCAGGTGGAATTGCTGATAGACATGGGGGCCTCAAACGTGGAGATCAACTC CTCTCTGTTAATGGAGTGAGTGTTGAAGGAGAACATCATGAAAAAGCTGTAGAACTGCTGAAAGCCGCAC AAGGAAAGGTTAAATTAGTGGTACGATACACACCCAAAGTCTTAGAAGAAATGGAGTCGCGCTTTGAAAA AATGAGATCAGCAAAACGCAGGCAACAGACCTAA >OriGene 5' read for NM_018362 unedited
CCGCGAATTCGGCACCAGGATGGCGGCGCTAGGGGAACCCGTGCGGCTGGAGAGAGATAT TTGTAGAGCAATTGAATTATTGGAAAAACTACAAAGGAGTGGAGAAGTACCACCACAGAA ACTTCAGGCTTTGCAAAGAGTCCTTCAAAGTGAATTCTGCAATGCTGTGAGAGAGGTATA TGAACATGTCTATGAGACTGTGGACATCAGTAGCAGTCCTGAAGTGAGAGCGAACGCTAC TGCAAAGGCTACTGTTGCTGCATTTGCTGCCAGTGAAGGACATTCTCATCCTCGAGTTGT TGAGCTACCAAAAACAGAAGAGGGCCTTGGATTCAATATTATGGGAGGCAAAGAACAAAA CTCTCCAATCTATATATCCCGAATAATTCCAGGTGGAATTGCTGATAGACATGGGGGCCT CAAACGTGGAGATCAACTCCTCTCTGTTAATGGAGTGAGTGTTGAAGGAGAACATCATGA AAAAGCTGTAGAACTGCTGAAAGCCGCACAAGGAAAGGTTAAATTAGTGGTACGATACAC ACCCAAAGTCTTAGAAGAAATGGAGTCGCGCTTTGAAAAATGAGATCAGCAAAACGCAGG CAACAGACCTAATACATTTCAAAACTTGATATTTCATTTTGCGTTTTAGCTAGAGAAGTT TTCCTTGTGACTTACTAATGGCTGCAATGCCAATGATTGNTAGAAAACAACAAATTTATC ATGAAATTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_018362 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | A TrueClone. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_018362.2, NP_060832.1 |
| RefSeq Size | 4729 bp |
| RefSeq ORF | 594 bp |
| Locus ID | 55327 |
| UniProt ID | Q9NUP9 |
| Domains | PDZ, L27 |
| Protein Families | Druggable Genome |
| Gene Summary | Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The Avian Influenza Virus NS1 ESEV PDZ Binding Motif Associates with Dlg1 and Scribble To Disrupt Cellular Tight Junctions
,Lisa Golebiewski, Hongbing Liu, Ronald T. Javier, and Andrew P. Rice,
J. Virol., Oct 2011; 85: 10639 - 10648.
[Lin7C]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208758 | LIN7C (Myc-DDK-tagged)-Human lin-7 homolog C (C. elegans) (LIN7C) |
CNY 2400.00 |
|
| RC208758L1 | Lenti ORF clone of Human lin-7 homolog C (C. elegans) (LIN7C), Myc-DDK-tagged |
CNY 4800.00 |
|
| RC208758L2 | Lenti ORF clone of Human lin-7 homolog C (C. elegans) (LIN7C), mGFP tagged |
CNY 5890.00 |
|
| RC208758L3 | Lenti ORF clone of Human lin-7 homolog C (C. elegans) (LIN7C), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC208758L4 | Lenti ORF clone of Human lin-7 homolog C (C. elegans) (LIN7C), mGFP tagged |
CNY 5890.00 |
|
| RG208758 | LIN7C (tGFP-tagged) - Human lin-7 homolog C (C. elegans) (LIN7C) |
CNY 4370.00 |
