RFTN1 (NM_015150) Human Untagged Clone
CAT＃: SC127336
RFTN1 (untagged)-Human raftlin, lipid raft linker 1 (RFTN1)
CNY 4312.00
CNY 7220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MIG2; PIB10; PIG9; RAFTLIN |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127336 sequence for NM_015150 edited (data generated by NextGen Sequencing)
ATGGGTTGCGGATTGAACAAGTTAGAGAAACGTGATGAAAAACGGCCTGGGAATATTTAT TCAACTTTGAAGAGGCCTCAGGTGGAAACCAAGATAGATGTGTCCTATGAATACCGCTTC CTGGAGTTCACGACTCTGAGTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCC TCCCTGCGTGACCTGCCCGCCCAGCTCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCG GCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCCCTGGAGCACATC TTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAA GGCTACATCTTGGAATTAGATTGCTGTTCCTCCTTAGACCACCCGACAGACCAGAAACTC ATCCCAGAGTTCATTAAGAAGATCCAGGAGGCTGCAAGCCAGGGCCTGAAATTCGTTGGT GTTATACCTCAGTACCATTCCTCTGTGAACTCGGCAGGCAGCAGTGCTCCGGTGTCTACT GCCAACAGCACCGAGGATGCCAGAGATGCAAAAAACGCACGTGGGGATCACGCGTCACTG GAGAATGAGAAACCGGGGACTGGGGATGTGTGCAGTGCTCCGGCTGGGAGAAACCAAAGC CCAGAGCCCAGCTCAGGCCCCAGAGGGGAGGTGCCCCTCGCCAAGCAGCCCAGCTCACCC TCCGGAGAGGGAGATGGTGGAGAACTTTCACCACAGGGGGTGAGCAAGACACTGGATGGA CCGGAGAGCAACCCCTTGGAGGTGCATGAAGAGCCACTCTCAGGGAAAATGGAGATCTTC ACCCTTTTCAACAAACCGAAGAGCCATCAGAAGTGCCGGCAATACTACCCTGTCACCATT CCTCTCCATGTCTCCAAGAATGGCCAGACAGTGAGCGGTTTGGACGCCAACTGGTTAGAG CACATGAGCGACCACTTCCGGAAAGGAGGCATGCTGGTGAACGCAGTCTTCTACCTTGGA ATAGTGAATGATTCCTTACATGGCTTGACAGATGGAGTATTCATCTTTGAAGCTGTTTCC ACAGAAGATAGCAAAACCATACAGGGCTATGATGCTATTGTGGTTGAACAATGGACAGTC CTGGAAGGTGTCGAAGTGCAGACAGACTACGTGCCCCTGCTGAACTCGCTGGCGGCCTAT GGCTGGCAGCTCACCTGTGTGCTACCAACTCCCGTCGTCAAGACTACCAGCGAGGGGAGT GTATCCACCAAGCAGATTGTCTTTCTTCAGAGACCGTGTCTACCTCAGAAAATCAAGAAG AAGGAATCGAAGTTTCAGTGGCGATTCTCCAGAGAAGAAATGCACAACAGGCAGATGAGG AAATCAAAAGGTAAACTCAGTGCCAGAGACAAACAACAAGCAGAAGAAAATGAGAAGAAC TTAGAAGACCAGTCTTCCAAAGCTGGAGACATGGGAAACTGTGTTTCGGGACAGCAGCAG GAGGGTGGAGTCTCCGAGGAGATGAAGGGCCCTGTCCAAGAGGACAAGGGAGAACAGCTG TCCCCTGGTGGCCTGCTGTGTGGGGTGGGTGTGGAGGGTGAGGCTGTGCAGAATGGTCCT GCCAGCCACAGCAGGGCCCTGGTGGGGATTTGCACTGGGCACTCCAATCCTGGAGAGGAT GCCAGGGACGGGGATGCTGAGGAAGTCAGAGAGCTTGGTACGGTTGAAGAAAACTGA Clone variation with respect to NM_015150.1 1296 t=>g;1488 a=>g >OriGene 5' read for NM_015150 unedited
ACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGACGCACCGATCGCCGGAGGGAC AGACACACGACCACGCGGCGCCACCGCCCACGCCTCCACCCACCGGCGCCCAAGTCCTCC CCGCGCCGCCTCCTCTGTATGGCACAAACTTTCCTCCCGGGACGGAACACGCTGCCTCAG GGAGCCCGCGACCGCGCCTTCTCCTCCGCCGGTCCCATACGCTGCTGAAATGGGTTGCGG ATTGAACAAGTTAGAGAAACGTGATGAAAAACGGCCTGGGAATATTTATTCAACTTTGAA GAGGCCTCAGGTGGAAACCAAGATAGATGTGTCCTATGAATACCGCTTCCTGGAGTTCAC GACTCTGAGTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGA CCTGCCCGCCCAGCTCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCC CTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCCCTGGAGCACATCTTTAGAGCCAT CCTGATCAAGATAACCGACAGATCTCAGAANACTGATCTTCACAATGAAGGGCTACATCT TGGAATTAGATTGCTGGTCCTCCTTAGACCCACCGACAGACCAGAAACTCATCCCAGAGT TCATTAAGAAGTCCAGGAGGGCTGCAGCCCAGGCCTGAANNTCGTTGGTGTATACCTCAG TACATTCCTCTGTGAACTCGCAGGCACAGTGCTCCGGTGTCTACTGCCACAGCACCGAGA TGCCAGAAAGCAAAAACGCCGGGGGATACGCCTACTGGAAATGAAACCGGGACTGGGGAT GGGGCAGGCTCCGGCTGGAAAACCAAGCAAGACCACCTAGCCCAGGGGGGGGGGCCCTGG CAGGACCCATTACCTCGGAAGGGAAAGGGGGGAA >OriGene 3' read for NM_015150 unedited
NTTCTAGCTTGACCGCGGCCGCTTTCTANATCGAGTTTTTTTTTTTTTTTTTTCACTAAC TCATAGATGATTTATTGCCGTAAGTAACTAAACAAGAGAAGAGACAGGCTGTGGGTTTGG TCAAGACAATCAGCATTCCCTCTCCAAGGTTCGCCAGTTGCATCTACCTAAAGCCTTAAT ACTTTCTGGACGATATACACATGATAAACACAGCATACATGGGTAACAACTTGACCAATG TTACACTGATTAAAATAGCACATAACAAGGGCGCCAGCCAGTCCCGATGCCCTGAAGTGA CAGAAGTAATGTGGTTTGTATGATGTGCTGAGTACAAAACCTTTAAAAACAACTTTTTGG CATTAATACTAACACAGAATACTTCCTTGAACATTCTGCAAAAGTAGGTGCAGAGACAGA ATTACTTCTTCATTTCCAGATTACCAGTATCTATAGGACTATTTTGAGAAAAGCTGGGAG GCGGAGCACCTCCCCTCCCCAATGTCATTTTCTTTGTCAAAGCAGAAGAGTCGAAGGGGT TTAGGTGGAGGAGGGCAGCTGACAGGGCTCCTGGAGTTGTTAAGTCACCAAGTAGCTGCA GGGGATGGACACTGCCCCACACGATGTGGGATGAACAGCAGCCTTGGTTTGTAGCCCAGG GTGTCCATGGAATTGACCCGAATGCTCCCTGNAGGCCCTGTGGCGAGGACAGGCACTGGA TGGTCCAGACCCTCNTGCTGNNAGAGTGNTGGAGCCAGNACTGGGCCTTCAGCCATGAGG NCTAGAATAACCTGACCTCTNGCATTCTACACTGGGTCATTATGACACCTTTCAGTGGAT GTGCAAAACCACACTGTCAGAACCTGCCCCTGGAGGCTCAGTGAGCCACAAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_015150 |
| Insert Size | 3080 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_015150.1, NP_055965.1 |
| RefSeq Size | 3033 bp |
| RefSeq ORF | 1737 bp |
| Locus ID | 23180 |
| UniProt ID | Q14699 |
| Gene Summary | Involved in protein trafficking via association with clathrin and AP2 complex (PubMed:27022195, PubMed:21266579). Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages; and internalization of poly(I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells; resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195, PubMed:21266579). Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity). May regulate B-cell antigen receptor-mediated signaling (PubMed:12805216). May play a pivotal role in the formation and/or maintenance of lipid rafts (PubMed:12805216).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223383 | RFTN1 (Myc-DDK-tagged)-Human raftlin, lipid raft linker 1 (RFTN1) |
CNY 4304.00 |
|
| RC223383L3 | Lenti ORF clone of Human raftlin, lipid raft linker 1 (RFTN1), Myc-DDK-tagged |
CNY 6704.00 |
|
| RC223383L4 | Lenti ORF clone of Human raftlin, lipid raft linker 1 (RFTN1), mGFP tagged |
CNY 6460.00 |
|
| RG223383 | RFTN1 (tGFP-tagged) - Human raftlin, lipid raft linker 1 (RFTN1) |
CNY 5904.00 |
