Phospholipase C beta 1 (PLCB1) (NM_182734) Human Untagged Clone
CAT＃: SC126664
PLCB1 (untagged)-Human phospholipase C, beta 1 (phosphoinositide-specific) (PLCB1), transcript variant 2
CNY 8176.00
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DEE12; EIEE12; PI-PLC; PLC-154; PLC-beta-1; PLC-I; PLC154; PLCB1A; PLCB1B |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_182734 edited
ACGGTGGGAGGTCTATATAAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACT TGTTCTTTTTGCAGCGGCCGCGAATTCGGCACGAGGGCAGAATCCGCCGCGACTGGCAGC CTCGGCTGACCGGCTCGGCTTCTCTTCGCCTTCCGAGGCTCCTCATCCACCGCGGGCTCC AGACCTCGCGTCCCGCCCGGGGCATGGCCGGGCGCTGCGCCCCCGCGCGCTCTGCCTGCT GAGCGGCGCCGGAGGGAGGTGCGGAGGCCGGGAGGCCGGGGAGGCCGGCTGGGAGCAGAG TCGAGCGCCTCCGGAGCAGAGAAAGGAGCCCGCGCCCCGCGCCCCGCGCCCCGCGCACGG TCCCCAGTCCCTGCCGCGCTCGCCCGGGCCGCCCGGAGCCCAGATGAGCCCAGATGGCCG GGGCTCAACCCGGAGTGCACGCCTTGCAACTCAAGCCCGTGTGCGTGTCCGACAGCCTCA AGAAGGGCACCAAATTCGTCAAGTGGGATGATGATTCAACTATTGTTACTCCAATTATTT TGAGGACTGACCCTCAGGGATTTTTCTTTTACTGGACAGATCAAAACAAGGAGACAGAGC TACTGGATCTCAGCCTTGTCAAAGATGCCAGATGTGGGAGACACGCCAAAGCTCCCAAGG ACCCCAAATTACGTGAACTTTTGGATGTGGGGAACATCGGGCGCCTGGAGCAGCGCATGA TCACAGTGGTGTATGGGCCTGACCTCGTGAACATCTCCCATTTGAATCTCGTGGCTTTCC AAGAAGAAGTGGCCAAGGAATGGACAAATGAGGTTTTCAGTTTGGCAACAAACCTGCTGG CCCAAAACATGTCCAGGGATGCATTTCTGGAAAAAGCCTATACTAAACTTAAGCTGCAAG TCACTCCAGAAGGGCGTATTCCTCTCAAAAACATATATCGCTTGTTTTCAGCAGATCGGA AGCGAGTTGAAACTGCTTTAGAGGCTTGTAGTCTTCCATCTTCAAGGAATGATTCAATAC CTCAAGAAGATTTCACTCCAGAAGTGTACAGAGTTTTCCTCAACAACCTTTGCCCTCGAC CTGAAATTGATAACATCTTTTCAGAATTTGGTGCAAAAAGCAAACCATATCTTACCGTTG ATCAGATGATGGATTTTATCAACCTTAAGCAGCGAGATCCTCGGCTTAATGAAATACTTT ATCCACCTCTAAAACAAGAGCAAGTCCAAGTATTGATTGAGAAGTATGAACCCAACAACA GCCTCGCCAGAAAAGGACAAATATCAGTGGATGGGTTCATGCGCTATCTGAGTGGAGAAG AAAACGGAGTCGTTTCACCTGAGAAACTGGATTTGAATGAAGACATGTCTCAGCCCCTTT CTCACTATTTCATTAATTCCTCGCACAACACCTACCTCACAGCTGGCCAACTGGCTGGAA ACTCCTCTGTTGAGATGTATCGCCAAGTGCTCCTGTCTGGTTGTCGCTGTGTGGAGCTGG ACTGCTGGAAGGGACGGACTGCAGAAGAGGAACCTGTCATCACCCATGGCTTCACCATGA CAACTGAAATATCTTTCAAGGAAGTGATAGAAGCAATTGCGGAGTGTGCATTTAAGACTT CACCTTTTCCAATTCTCCTTTCGTTTGAGAACCATGTGGATTCCCCAAAGCAGCAAGCCA AGATGGCGGAGTACTGCCGACTGATCTTTGGGGATGCCCTTCTCATGGAGCCCCTGGAAA AATATCCACTGGAATCTGGAGTTCCTCTTCCAAGCCCTATGGATTTAATGTATAAAATTT TGGTGAAAAATAAGAAGAAATCACACAAGTCATCAGAAGGAAGCGGCAAAAAGAAGCTCT CAGAACAAGCCTCCAACACCTACAGTGACTCCTCCAGCATGTTCGAGCCCTCATCCCCAG GAGCCGGAGAAGCTGATACGGAAAGTGACGACGACGATGATGATGATGACTGTAAAAAAT CTTCAATGGATGAGGGGACTGCTGGAAGTGAGGCTATGGCCACAGAAGAAATGTCTAATC TGGTGAACTATATTCAGCCAGTCAAGTTTGAGTCATTTGAAATTTCAAAAAAAAGAAATA AAAGTTTTGAAATGTCTTCCTTCGTGGAAACCAAAGGACTTGAACAACTCACCAAGTCTC CAGTGGAATTTGTAGAATATAACAAAATGCAGCTTAGCAGGATATATCCAAAAGGAACAC GTGTGGATTCATCCAACTATATGCCTCAGCTCTTCTGGAATGCAGGTTGTCAGATGGTGG CACTTAATTTCCAGACAATGGACCTGGCTATGCAAATAAATATGGGGATGTATGAATACA ACGGGAAGAGTGGCTACAGATTGAAGCCAGAGTTCATGAGGAGGCCTGACAAGCATTTTG ATCCATTTACTGAAGGCATCGTAGATGGGATAGTGGCAAACACTTTGTCTGTTAAGATTA TTTCAGGTCAGTTTCTTTCTGATAAGAAAGTTGGGACTTACGTGGAAGTAGATATGTTTG GTTTGCCTGTGGATACAAGGAGGAAGGCATTTAAGACCAAAACATCCCAAGGAAATGCTG TGAATCCTGTCTGGGAAGAAGAACCTATTGTGTTCAAAAAGGTGGTTCTTCCTACTCTGG CCTGTTTGAGAATAGCAGTTTATGAAGAAGGAGGTAAATTCATTGGCCACCGTATCTTGC CAGTGCAAGCCATTCGGCCAGGCTATCACTATATCTGTCTAAGGAATGAAAGGAACCAGC CTCTGACGCTGCCTGCTGTCTTTGTCTACATAGAAGTGAAAGACTATGTGCCAGACACAT ATGCAGATGTCATCGAAGCTTTATCAAACCCAATCCGATATGTGAACCTGATGGAACAGA GAGCTAAGCAATTGGCTGCTTTGACACTGGAAGATGAAGAAGAAGTAAAGAAAGAGGCTG ATCCTGGAGAAACACCATCAGAGGCTCCAAGTGAAGCGAGAACGACTCCAGCAGAAAATG GGGTGAATCACACTACAACCCTGACACCCAAGCCACCCTCCCAGGCTCTCCACAGCCAGC CAGCTCCAGGTTCTGTAAAGGCACCTGCCAAAACAGAAGATCTTATTCAGAGTGTCTTAA CAGAAGTGGAAGCACAGACCATCGAAGAACTAAAGCAACAGAAATCGTTTGTGAAACTTC AAAAGAAACACTACAAAGAAATGAAAGACCTGGTTAAGAGACACCACAAGAAAACCACTG ACCTTATCAAAGAACACACTACCAAGTATAATGAAATTCAGAATGACTACTTGAGAAGGA GAGCCGCTTTGGAAAAGTCCGCCAAAAAGGACAGTAAGAAAAAATCGGAACCCAGCAGCC CTGATCATGGTTCATCAACGATTGAGCAAGACCTCGCTGCCCTGGATGCTGAAATGACCC AAAAGTTAATAGACTTGAAGGACAAACAACAGCAGCAGCTGCTTAATCTTCGGCAAGAAC AGTATTATAGTGAAAAATACCAGAAGCGAGAACATATTAAACTGCTTATTCAAAAGTTGA CGGATGTCGCAGAAGAGTGTCAGAACAATCAGTTAAAGAAGCTCAAAGAAATCTGTGAGA AAGAAAAGAAAGAATTAAAGAAGAAAATGGATAAAAAGAGGCAGGAGAAGATAACAGAAG CTAAATCCAAAGACAAAAGTCAGATGGAAGAGGAGAAGACAGAGATGATCCGGTTATATA TCCAGGAAGTGGTGCAGTATATCAAGAGGCTAGAAGAAGCGCAAAGTAAACGGCAAGAAA AACTCGTAGAGAAACACAAGGAAATACGTCAGCAGATCCTGGATGAAAAGCCCAAGGGGG AAGGTTCCTCCTCATTCTTGTCGGAAACTTGCCATGAGGATCCCTCTGTTTCCCCCAACT TTACTCCCCCCAACCCTCAAGCTCTCAAGTGGTGATCTAGATTGCGGCCGCGGTCATA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_182734 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_182734.1, NP_877398.1 |
| RefSeq Size | 6823 bp |
| RefSeq ORF | 3522 bp |
| Locus ID | 23236 |
| UniProt ID | Q9NQ66 |
| Protein Families | Druggable Genome |
| Protein Pathways | Alzheimer's disease, Calcium signaling pathway, Chemokine signaling pathway, Gap junction, GnRH signaling pathway, Huntington's disease, Inositol phosphate metabolism, Long-term depression, Long-term potentiation, Melanogenesis, Metabolic pathways, Phosphatidylinositol signaling system, Vascular smooth muscle contraction, Wnt signaling pathway |
| Gene Summary | The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) includes an alternate exon in the 3' end compared to variant 1. This exon contains an in-frame stop codon, and the resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216150 | PLCB1 (Myc-DDK-tagged)-Human phospholipase C, beta 1 (phosphoinositide-specific) (PLCB1), transcript variant 2 |
CNY 8168.00 |
|
| RC216150L3 | Lenti-ORF clone of PLCB1 (Myc-DDK-tagged)-Human phospholipase C, beta 1 (phosphoinositide-specific) (PLCB1), transcript variant 2 |
CNY 13590.00 |
|
| RC216150L4 | Lenti-ORF clone of PLCB1 (mGFP-tagged)-Human phospholipase C, beta 1 (phosphoinositide-specific) (PLCB1), transcript variant 2 |
CNY 13590.00 |
|
| RG216150 | PLCB1 (tGFP-tagged) - Human phospholipase C, beta 1 (phosphoinositide-specific) (PLCB1), transcript variant 2 |
CNY 12830.00 |
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