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Protein Z (PROZ) (NM_003891) Human Untagged Clone
CAT＃: SC125554
PROZ (untagged)-Human protein Z, vitamin K-dependent plasma glycoprotein (PROZ)
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PZ |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC125554 sequence for NM_003891 edited (data generated by NextGen Sequencing)
ATGGCAGGCTGCGTCCCACTGCTCCAGGGCCTGGTCCTGGTCCTCGCCCTCCATCGTGTG GAGCCCTCAGTATTTCTCCCGGCCTCCAAAGCAAACGACGTTCTGGTGAGGTGGAAGCGT GCGGGCTCCTATCTTCTGGAAGAACTCTTCGAGGGAAACTTGGAAAAAGAATGTTATGAA GAAATCTGTGTCTATGAAGAAGCAAGAGAAGTGTTTGAAAATGAAGTAGTCACTGATGAA TTCTGGAGACGATATAAGGGCGGCTCCCCGTGCATCTCCCAGCCCTGCCTCCACAACGGC TCTTGCCAGGACAGCATCTGGGGCTACACCTGCACCTGCTCCCCCGGCTATGAGGGCAGC AACTGCGAGCTGGCTAAAAATGAATGTCACCCAGAGCGGACTGATGGGTGTCAACACTTC TGCCTCCCAGGACAGGAATCCTACACGTGCAGCTGTGCTCAGGGCTACAGGCTTGGTGAG GACCACAAACAGTGTGTGCCCCACGACCAGTGTGCCTGCGGGGTGCTGACCTCTGAGAAG CGTGCACCGGATCTACAGGACCTCCCGTGGCAGGTAAAGTTAACAAATTCCGAAGGAAAA GACTTCTGTGGTGGTGTTATAATACGGGAAAATTTTGTACTGACAACAGCAAAATGTTCA CTGTTACACAGGAATATTACTGTAAAAACATATTTTAACAGAACGAGCCAAGACCCGCTG ATGATCAAGATAACGCACGTCCATGTGCACATGCGGTATGACGCGGACGCGGGGGAGAAT GACCTGTCACTGCTGGAGCTGGAGTGGCCCATCCAGTGCCCAGGTGCGGGGCTCCCCGTG TGCACCCCTGAGAAAGACTTCGCTGAGCACCTCCTCATCCCACGCACCAGGGGCCTCCTC AGCGGCTGGGCACGCAATGGCACTGACCTGGGCAACTCGCTGACCACGCGGCCTGTCACA CTTGTGGAGGGGGAGGAGTGCGGGCAGGTCCTGAATGTGACTGTCACCACCAGGACCTAC TGTGAGAGAAGCAGCGTGGCGGCCATGCACTGGATGGATGGAAGTGTGGTCACCAGAGAA CACAGAGGCTCCTGGTTTCTCACGGGGGTCCTGGGCTCGCAGCCAGTAGGAGGGCAGGCT CACATGGTCCTTGTCACCAAGGTCTCCAGGTACTCACTCTGGTTTAAACAGATCATGAAC TAA Clone variation with respect to NM_003891.1 >OriGene 5' read for NM_003891 unedited
CCACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCGGGTGGGAATGGCAGGCTGCGTC CCACTGCTCCAGGGCCTGGTCCTGGTCCTCGCCCTCCATCGTGTGGAGCCCTCAGTATTT CTCCCGGCCTCCAAAGCAAACGACGTTCTGGTGAGGTGGAAGCGTGCGGGCTCCTATCTT CTGGAAGAACTCTTCGAGGGAAACTTGGAAAAAGAATGTTATGAAGAAATCTGTGTCTAT GAAGAAGCAAGAGAAGTGTTTGAAAATGAAGTAGTCACTGATGAATTCTGGAGACGATAT AAGGGCGGCTCCCCGTGCATCTCCCAGCCCTGCCTCCACAACGGCTCTTGCCAGGACAGC ATCTGGGGCTACACCTGCACCTGCTCCCCCGGCTATGAGGGCAGCAACTGCGAGCTGGCT AAAAATGAATGTCACCCAGAGCGGACTGATGGGTGTCAACACTTCTGCCTCCCAGGACAG GAATCCTACACGTGCAGCTGTGCTCAGGGCTACAGGCTTGGTGAGGACCACAAACAGTGT GTGCCCCACGACCAGTGTGCCTGCGGNGTGCTGACCTCTGAGAAGCGTGCACCGGATCTA CAGGACCTCCCGTGGCAGGTAAAGTTAACAAATTCCGAAGGANAAGACTTCTGTGGTGGT GTTATAATACGGGAAAATTTTGTACTGACAACAGCAAAATGTTCACTGTTACACAGGAAT ATTACTGTAAAAACATATTTTAACAGAACGAGCCAAGACN |
| Restriction Sites | Please inquire |
| ACCN | NM_003891 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003891.1, NP_003882.1 |
| RefSeq Size | 1485 bp |
| RefSeq ORF | 1203 bp |
| Locus ID | 8858 |
| UniProt ID | P22891 |
| Protein Families | Druggable Genome, Protease, Secreted Protein |
| Gene Summary | This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210379 | PROZ (Myc-DDK-tagged)-Human protein Z, vitamin K-dependent plasma glycoprotein (PROZ) |
CNY 3,656.00 |
|
| RC210379L1 | Lenti ORF clone of Human protein Z, vitamin K-dependent plasma glycoprotein (PROZ), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210379L2 | Lenti ORF clone of Human protein Z, vitamin K-dependent plasma glycoprotein (PROZ), mGFP tagged |
CNY 5,890.00 |
|
| RC210379L3 | Lenti ORF clone of Human protein Z, vitamin K-dependent plasma glycoprotein (PROZ), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210379L4 | Lenti ORF clone of Human protein Z, vitamin K-dependent plasma glycoprotein (PROZ), mGFP tagged |
CNY 5,890.00 |
|
| RG210379 | PROZ (tGFP-tagged) - Human protein Z, vitamin K-dependent plasma glycoprotein (PROZ) |
CNY 4,370.00 |
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