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ApoER2 (LRP8) (NM_033300) Human Untagged Clone
CAT＃: SC124693
LRP8 (untagged)-Human low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (LRP8), transcript variant 2
CNY 5,816.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APOER2; HSZ75190; LRP-8; MCI1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_033300, the custom clone sequence may differ by one or more nucleotides
ATGGGCCTCCCCGAGCCGGGCCCTCTCCGGCTTCTGGCGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGC TGCAGCTCCAGCATCTTGCGGCGGCAGCGGCTGATCCGCTGCTCGGCGGCCAAGGGCCGGCCAAGGATTG CGAAAAGGACCAATTCCAGTGCCGGAACGAGCGCTGCATCCCCTCTGTGTGGAGATGCGACGAGGACGAT GACTGCTTAGACCACAGCGACGAGGACGACTGCCCCAAGAAGACCTGTGCAGACAGTGACTTCACCTGTG ACAACGGCCACTGCATCCACGAACGGTGGAAGTGTGACGGCGAGGAGGAGTGTCCTGATGGCTCCGATGA GTCCGAGGCCACTTGCACCAAGCAGGTGTGTCCTGCAGAGAAGCTGAGCTGTGGACCCACCAGCCACAAG TGTGTACCTGCCTCGTGGCGCTGCGACGGGGAGAAGGACTGCGAGGGTGGAGCGGATGAGGCCGGCTGTG CTACCTGGCTGAACGAGTGTCTGCACAACAATGGCGGCTGCTCACACATCTGCACTGACCTCAAGATTGG CTTTGAATGCACGTGCCCAGCAGGCTTCCAGCTCCTGGACCAGAAGACCTGTGGCGACATTGATGAGTGC AAGGACCCAGATGCCTGCAGCCAGATCTGTGTCAATTACAAGGGCTATTTTAAGTGTGAGTGCTACCCTG GCTACGAGATGGACCTACTGACCAAGAACTGCAAGGCTGCTGCTGGCAAGAGCCCATCCCTAATCTTCAC CAACCGGCACGAGGTGCGGAGGATCGACCTGGTGAAGCGGAACTATTCACGCCTCATCCCCATGCTCAAG AATGTCGTGGCACTAGATGTGGAAGTTGCCACCAATCGCATCTACTGGTGTGACCTCTCCTACCGTAAGA TCTATAGCGCCTACATGGACAAGGCCAGTGACCCGAAAGAGCAGGAGGTCCTCATTGACGAGCAGTTGCA CTCTCCAGAGGGCCTGGCAGTGGACTGGGTCCACAAGCACATCTACTGGACTGACTCGGGCAATAAGACC ATCTCAGTGGCCACAGTTGATGGTGGCCGCCGACGCACTCTCTTCAGCCGTAACCTCAGTGAACCCCGGG CCATCGCTGTTGACCCCCTGCGAGGGTTCATGTATTGGTCTGACTGGGGGGACCAGGCCAAGATTGAGAA ATCTGGGCTCAACGGTGTGGACCGGCAAACACTGGTGTCAGACAATATTGAATGGCCCAACGGAATCACC CTGGATCTGCTGAGCCAGCGCTTGTACTGGGTAGACTCCAAGCTACACCAACTGTCCAGCATTGACTTCA GTGGAGGCAACAGAAAGACGCTGATCTCCTCCACTGACTTCCTGAGCCACCCTTTTGGGATAGCTGTGTT TGAGGACAAGGTGTTCTGGACAGACCTGGAGAACGAGGCCATTTTCAGTGCAAATCGGCTCAATGGCCTG GAAATCTCCATCCTGGCTGAGAACCTCAACAACCCACATGACATTGTCATCTTCCATGAGCTGAAGCAGC CAAGAGCTCCAGATGCCTGTGAGCTGAGTGTCCAGCCTAATGGAGGCTGTGAATACCTGTGCCTTCCTGC TCCTCAGATCTCCAGCCACTCTCCCAAGTACACATGTGCCTGTCCTGACACAATGTGGCTGGGTCCAGAC ATGAAGAGGTGCTACCGAGCACCTCAATCTACCTCAACTACGACGTTAGCTTCTACCATGACGAGGACAG TACCTGCCACCACAAGAGCCCCCGGGACCACCGTCCACAGATCCACCTACCAGAACCACAGCACAGAGAC ACCAAGCCTGACAGCTGCAGTCCCAAGCTCAGTTAGTGTCCCCAGGGCTCCCAGCATCAGCCCGTCTACC CTAAGCCCTGCAACCAGCAACCACTCCCAGCACTATGCAAATGAAGACAGTAAGATGGGCTCAACAGTCA CTGCCGCTGTTATCGGGATCATCGTGCCCATAGTGGTGATAGCCCTCCTGTGCATGAGTGGATACCTGAT CTGGAGAAACTGGAAGCGGAAGAACACCAAAAGCATGAATTTTGACAACCCAGTCTACAGGAAAACAACA GAAGAAGAAGACGAAGATGAGCTCCATATAGGGAGAACTGCTCAGATTGGCCATGTCTATCCTGCAGCAA TCAGCAGCTTTGATCGCCCACTGTGGGCAGAGCCCTGTCTTGGGGAGACCAGAGAACCGGAAGACCCAGC CCCTGCCCTCAAGGAGCTTTTTGTCTTGCCGGGGGAACCAAGGTCACAGCTGCACCAACTCCCGAAGAAC CCTCTTTCCGAGCTGCCTGTCGTCAAATCCAAGCGAGTGGCATTAAGCCTTGAAGATGATGGACTACCCT GA >OriGene 5' read for NM_033300 unedited
GCCGCGAAATCGGCACGAGGGCAACCCCGGCGCCGCGGCAAGGACTCGGAGGGCTGAGAC GCGGCGGCGGCGGCGCGGGGAGCGCGGGGCGCGGCGGCCGGAGCCCCGGGCCCGCCATGG GCCTCCCCGAGCCGGGCCCTCTCCGGCTTCTGGCGCTGCTGCTGCTGCTGCTGCTGCTGC TGCTGCTGCGGCTCCAGCATCTTGCGGCGGCAGCGGCTGATCCGCTGCTCGGCGGCCAAG GGCCGGCCAAGGAGTGCGAAAAGGACCAATTCCAGTGCCGGAACGAGCGCTGCATCCCCT CTGTGTGGAGATGCGACGAGGACGATGACTGCTTAGACCACAGCGACGAGGACGACTGCC CCAAGAAGACCTGTGCAGACAGTGACTTCACCTGTGACAACGGCCACTGCATCCACGAAC GGTGGAAGTGTGACGGCGAGGAGGAGTGTCCTGATGGCTCCGATGAGTCCGAGGCCACTT GCACCAAGCANGGTGTGTCCTGCAGAGAAGCTGAGCTGTGGACCCACCAGCCACAAGTGT GTACCTGCCTCGTGGCGCTGCGACGGGGAGAAGGACTGCGAGGGTGGAGCGGATGAGGCC GGCTGTGCTACCTCACTGGGCACCTGCCGTGGGGACGAGTTCCAGTGTGGGGATGGGACA TGTGTCCTTGCATCGAGCACTGCACCAGGAGCANGACTGTCCAGAGGGAGTGATGAAGCT GGCTGCTACAGGGCTGAACGGTGTCTGCACACATGGGCGCTGCTACACATCTGCACTGAC TCAAGATGGCTTGAATGCCCTGCCAGCAGCTTCCACTCCTGACANAAACCTGGGCAAATT GATGATGCAGGACCAATCCTGAACCAAACTGC >OriGene 3' read for NM_033300 unedited
GCTATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTACTTATGTT GATGGATAGCCACAAAGCATAATCATCTTATTTACAAAAAACAAATGCCCCAAAACCTAA AAAAGCCCCCCCAGCAACCAAACATCTTCTGTAAATATAGTTTTTAAATGATGAGTAAGG TACTGTGCCATTGGCCCCCATTTGGTTATGTGCATCATGTTAGTCAGCAGTAGCCATTCC ACGAATTCCTCATGGGTAGTGCAACCAGTTAAAAAGTGTATAAAACATTATACATAGAAA AACTCTCACATCCTTTGGATGTTTGCAGTTCATCATAACTTTGTGGTTACCTTTCCGCAA CATAAATTTAAAAAAAAAATCACACACACACATACACTCACACAGACCCATATATAGAAA CCCATTCATCCAGTCATACACCATCCAGAGTGTAGTGCATGGGACTGAATTCCATGAGGC ACGAAGGGGGTGATCCCATCCTCAGGGTAGTCCATCATCTTCAAGGCTTAATGCCACTCG CTTGGATTTGACGACAGGCAGCTCGGAAAGAGGGTTCTTCGGGAGTTGGTGCAGCTGTGA CCTTGGTTCCCCCGGCAAGACANAAAGCTCCTTGAGGGCAGGGGCTGGGTCTTCCGGTTC TCTGGTCTTCCCAGACAGGGCTCTGCCCCAGTGGGCGATCAAGCTGCTGATTGCTGCAGG ATAAACATGCCCATCTGGACCAGTCTCCCTATATGGAGCCCATCTTCATTTTCTTCCTCG GGTGGTTTCTGGAGAATGGGGTTGCCAAAATTCAGCTTTTGGGCGTCCTCCCGCTTCCGG TTCTCCAAATAAGGTTCCCCTCCCGCCCCGAAGGCTATCCCCTTTGGGCCCCAGAACCCC AAAACCGGGGCCGCCTGTGGGCCATCTTACGGTTCCTTCGAAAGGTTGGAAACGTCCTCG GTTTCGGTTTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_033300 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_033300.2, NP_150643.2 |
| RefSeq Size | 7273 bp |
| RefSeq ORF | 2382 bp |
| Locus ID | 7804 |
| UniProt ID | Q14114 |
| Domains | ldl_recept_b, EGF_CA, ldl_recept_a, EGF, EGF |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Gene Summary | This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011] Transcript Variant: This variant (2) lacks two consecutive coding exons but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222397 | LRP8 (Myc-DDK-tagged)-Human low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (LRP8), transcript variant 2 |
CNY 5,800.00 |
|
| RC222397L3 | Lenti-ORF clone of LRP8 (Myc-DDK-tagged)-Human low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (LRP8), transcript variant 2 |
CNY 7,700.00 |
|
| RC222397L4 | Lenti-ORF clone of LRP8 (mGFP-tagged)-Human low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (LRP8), transcript variant 2 |
CNY 7,700.00 |
|
| RG222397 | LRP8 (tGFP-tagged) - Human low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (LRP8), transcript variant 2 |
CNY 6,370.00 |
