PTGIS (NM_000961) Human Untagged Clone
CAT＃: SC123875
PTGIS (untagged)-Human prostaglandin I2 (prostacyclin) synthase (PTGIS)
CNY 3728.00
CNY 7220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CYP8; CYP8A1; PGIS; PTGI |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC123875 sequence for NM_000961 edited (data generated by NextGen Sequencing)
ATGGCTTGGGCCGCGCTCCTCGGCCTCCTGGCCGCACTGTTGCTGCTGCTGCTACTGAGC CGCCGCCGCACGCGGCGACCTGGTGAGCCTCCCCTGGACCTGGGCAGCATCCCCTGGTTG GGGTATGCCTTGGACTTTGGAAAAGATGCTGCCAGCTTCCTCACGAGGATGAAGGAGAAG CACGGTGACATCTTTACTATACTGGTTGGGGGCAGGTATGTCACCGTTCTCCTGGACCCA CACTCCTACGACGCGGTGGTGTGGGAGCCTCGCACCAGGCTCGACTTCCATGCCTATGCC ATCTTCCTCATGGAGAGGATTTTTGATGTGCAGCTTCCACATTACAGCCCCAGTGATGAA AAGGCCAGGATGAAACTGACTCTTCTCCACAGAGAGCTCCAGGCACTCACAGAAGCCATG TATACCAACCTCCATGCAGTGCTGTTGGGCGATGCTACAGAAGCAGGCAGTGGCTGGCAC GAGATGGGTCTCCTCGACTTCTCCTACAGCTTCCTGCTCAGAGCCGGCTACCTGACTCTT TACGGAATTGAGGCGCTGCCACGCACCCATGAAAGCCAGGCCCAGGACCGCGTCCACTCA GCTGATGTCTTCCACACCTTTCGCCAGCTCGACCGGCTGCTCCCCAAACTGGCCCGTGGC TCCCTGTCAGTGGGGGACAAGGACCACATGTGCAGTGTCAAAAGTCGCCTGTGGAAGCTG CTATCCCCAGCCAGGCTGGCCAGGCGGGCCCACCGGAGCAAATGGCTGGAGAGTTACCTG CTGCACCTGGAGGAGATGGGTGTGTCAGAGGAGATGCAGGCACGGGCCCTGGTGCTGCAG CTGTGGGCCACACAGGGGAATATGGGTCCCGCTGCCTTCTGGCTCCTGCTCTTCCTTCTC AAGAATCCTGAAGCCCTGGCTGCTGTCCGCGGAGAGCTCGAGAGTATCCTTTGGCAAGCG GAGCAGCCTGTCTCGCAGACGACCACTCTCCCACAGAAGGTTCTAGACAGCACACCTGTG CTTGATAGCGTGCTGAGTGAGAGCCTCAGGCTTACAGCTGCCCCCTTCATCACCCGCGAG GTTGTGGTGGACCTGGCCATGCCCATGGCAGACGGGCGAGAATTCAACCTGCGACGTGGT GACCGCCTCCTCCTCTTCCCCTTCCTGAGCCCCCAGAGAGACCCAGAAATCTACACAGAC CCAGAGGTATTTAAATACAACCGATTCCTGAACCCTGACGGATCAGAGAAGAAAGACTTT TACAAGGATGGGAAACGGCTGAAGAATTACAACATGCCCTGGGGGGCGGGGCACAATCAC TGCCTGGGGAGGAGTTATGCGGTCAACAGCATCAAACAATTTGTGTTCCTTGTGCTGGTG CACTTGGACTTGGAGCTGATCAACGCAGATGTGGAGATCCCTGAGTTTGACCTCAGCAGG TACGGCTTCGGTCTGATGCAGCCGGAACACGACGTGCCCGTCCGCTACCGCATCCGCCCA TGA Clone variation with respect to NM_000961.3 >OriGene 5' read for NM_000961 unedited
TCAGAATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGCCCCGCCAGC CCCGCCAGCCCCGCGATGGCTTGGGCCGCGCTCCTCGGCCTCCTGGCCGCACTGTTGCTG CTGCTGCTACTGAGCCGCCGCCGCACGCGGCGACCTGGTGAGCCTCCCCTGGACCTGGGC AGCATCCCCTGGTTGGGGTATGCCTTGGACTTTGGAAAAGATGCTGCCAGCTTCCTCACG AGGATGAAGGAGAAGCACGGTGACATCTTTACTATACTGGTTGGGGGCAGGTATGTCACC GTTCTCCTGGACCCACACTCCTACGACGCGGTGGTGTGGGAGCCTCGCACCAGGCTCGAC TTCCATGCCTATGCCATCTTCCTCATGGAGAGGATTTTTGATGTGCAGCTTCCACATTAC AGCCCCAGTGATGAAAAGGCCAGGATGAAACTGACTCTTCTCCACAGAGAGCTCCAGGCA CTCACAGAAGCCATGTATACCAACCTCCATGCAGTGCTGTTGGGCGATGCTACAGAAGCA GGCAGTGGCTGGCACGAGATGGGTCTCCTCGACTTCTCCTACAGCTTCCTGCTCAGAGCC GGCTACCTGACTCTTTACGGAATTGAGGCGCTGCCACGCACCCATGAAAGCCAGGCCCAG GACCGCGTCCACTCAGCTGATGTCTTCCACACCTTTCGCCAGCTCGACCGGCTGCTCCCC AAACTGGCCCGTGGCTCCCTGTCAGTGGGGGACAAGACCACATGTGCAGTGTCAAAAGTC GCCTGTGGAAGCTGCTATCCCCAGCCAGGCTGCCAGGCGGGCCCACGGAACCAAATGGTG GAGAAGTACCCGCTGCACCTGGAGGAAATGGGGGTGTCAAAAGAGATGCAAGCACGGGCC CTGGTGCTGCACCTTGGGAGCACAAGGGGAAAA >OriGene 3' read for NM_000961 unedited
GCACGTCGTGTTCCGGCTGCATCAGACCGAAGCCGTACCTGCTGAGGTCAAACTCAGGGA TCTCCACATCTGCGTTGATCAGCTCCAAGTCCAAGTGCACCAGCACAAGGAACACAAATT GTTTGATGCTGTTGACCGCATAACTCCTCCCCAGGCAGTGATTGTGCCCCGCCCCCCAGG GCATGTTGTAATTCTTCAGCCGTTTCCCATCCTTGTAAAAGTCTTTCTTCTCTGATCCGT CAGGGTTCAGGAATCGGTTGTATTTAAATACCTCTGGGTCTGTGTAGATTTCTGGGTCTC TCTGGGGGCTCAGGAAGGGGAAGAGGAGGAGGCGGTCACCACGTCGCAGGTTGAATTCTC GCCCGTCTGCCATGGGCATGGCCAGGTCCACCACAACCTCGCGGGTGATGAAGGGGGCAG CTGTAAGCCTGAGGCTCTCACTCAGCACGCTATCAAGCACAGGTGTGCTGTCTAGAACCT TCTGTGGGAGAGTGGTCGTCTGCGAGACAGGCTGCTCCGCTTGCCAAAGGATACTCTCGA GCTCTCCGCGGACAGCAGCCAGGGCTTCAGGATTCTTGAGAAGGAAGAGCAGGAGCCAGA AAGCAGCGGGACCCATATTCCCCTGTGTGGCCCACAGCTGCAGCACCAGGGCCCGTGCCT GCATCTCCTCTGACACACCCATCTCCTCCAGGTGCAGCAGGTAACTCTCCAGCCATTTGC TCCGGTGGGCCCGCCTGGCN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000961 |
| Insert Size | 3700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000961.3, NP_000952.1 |
| RefSeq Size | 5603 bp |
| RefSeq ORF | 1503 bp |
| Locus ID | 5740 |
| UniProt ID | Q16647 |
| Protein Families | Druggable Genome, P450, Transmembrane |
| Protein Pathways | Arachidonic acid metabolism, Metabolic pathways |
| Gene Summary | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211030 | PTGIS (Myc-DDK-tagged)-Human prostaglandin I2 (prostacyclin) synthase (PTGIS) |
CNY 3656.00 |
|
| RC211030L1 | Lenti ORF clone of Human prostaglandin I2 (prostacyclin) synthase (PTGIS), Myc-DDK-tagged |
CNY 6056.00 |
|
| RC211030L2 | Lenti ORF clone of Human prostaglandin I2 (prostacyclin) synthase (PTGIS), mGFP tagged |
CNY 5890.00 |
|
| RC211030L3 | Lenti ORF clone of Human prostaglandin I2 (prostacyclin) synthase (PTGIS), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC211030L4 | Lenti ORF clone of Human prostaglandin I2 (prostacyclin) synthase (PTGIS), mGFP tagged |
CNY 6056.00 |
|
| RG211030 | PTGIS (tGFP-tagged) - Human prostaglandin I2 (prostacyclin) synthase (PTGIS) |
CNY 5256.00 |
