THSD4 (BC008840) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	ADAMTSL-6; ADAMTSL6; FVSY9334; PRO34005
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC008840 edited GTGAGGAGGGCTGTGTTTGCTTCCCCTTCTGCGATGATTCTAAGTTTTCTGAGGCCTCCC CAGCCATGCTGAACTAGCATTGGCTGTGATGACTACTTAGGCTCCGACAAAGTCGTGGAC AAATGTGGGGTGTGTGGAGGAGACAACACGGGCTGTCAGGTTGTGTCGGGCGTGTTTAAG CATGCCCTCACCAGCCTGGGCTACCACCGCGTCGTGGAGATTCCCGAGGGAGCCACGAAA ATCAACATCACGGAGATGTACAAGAGCAACAACTATTTGGCCCTGAGAAGTCGTTCTGGA CGCTCCATCATCAATGGGAACTGGGCAATTGATCGACCAGGAAAATACGAGGGCGGAGGG ACCATGTTCACCTACAAGCGTCCAAATGAGATTTCGAGCACTGCCGGAGAGTCCTTTTTG GCGGAAGGTCCCACCAACGAGATCTTGGATGTCTACATGATACACCAGCAGCCAAACCCA GGCGTGCACTACGAGTACGTGATCATGGGGACCAACGCCATCAGCCCCCAGGTGCCACCC CACAGGAGACCAGGGGAACCCTTCAATGGCCAGATGGTGACAGAAGGCAGGAGCCAGGAG GAGGGAGAACAGAAAGGGAGGAACGAGGAGAAGGAAGACTTGCGTGGGGAGGCCCCTGAG ATGTTCACCTCAGAATCGGCACAGACCTTCCCAGTCAGGCATCCAGACAGATTTTCTCCC CATCGACCGGACAACTTGGTGCCACCAGCACCGCAGCCCCCACGGCGCAGCCGGGATCAC AACTGGAAGCAGCTTGGGACAACAGAATGTTCCACGACCTGTGGGAAAGGATCGCAGTAC CCTATTTTCCGCTGTGTGCACAGAAGCACTCATGAAGAGGCTCCTGAGAGTTACTGTGAC TCCAGCATGAAGCCGACCCCCGAGGAGGAGCCCTGCAACATCTTCCCTTGCCCAGCCTTC TGGGACATCGGGGAGTGGTCTGAGTGCAGCAAGACCTGTGGCCTGGGCATGCAGCACCGC CAGGTTCTGTGCCGCCAGGTGTACGCCAACCGCAGCCTGACGGTGCAGCCCTACCGCTGC CAGCACCTGGAGAAACCTGAGACCACCAGCACCTGCCAACTCAAGATCTGCAGCGAGTGG CAGATCCGGACCGACTGGACCTCGTGCTCGGTGCCCTGCGGCGTGGGACAGAGGACCCGT GATGTGAAGTGTGTGAGCAACATTGGGGATGTGGTTGACGATGAGGAATGCAACATGAAG CTCCGGCCGAATGACATTGAGAACTGCGACATGGGACCCTGTGCCAAGAGCTGGTTCCTC ACCGAGTGGAGCGAAAGGTGCTCAGCGGAGTGTGGGGCCGGAGTGCGGACACGCTCGGTG GTGTGCATGACCAACCATGTCAGCAGCCTGCCCCTGGAGGGCTGTGGGAACAACCGGCCG GCAGAGGCCACCCCATGTGACAACGGACCCTGCACGGGCAAGGTGGAGTGGTTTGCCGGG AGCTGGAGTCAGTGTTCCATCGAGTGTGGGAGCGGGACGCAACAGAGGGAGGTGATTTGT GTTAGAAAGAATGCAGACACCTTTGAAGTGTTGGACCCCTCTGAATGTTCTTTCCTGGAG AAACCCCCCAGCCAGCAATCCTGCCACCTCAAGCCTTGCGGAGCCAAATGGTTTAGCACC GAATGGAGCATGAGTCTACAAAGAGCCATGCTCACCAGGCCAAGTTGAAGGAGACAAACT TCAAAAACACCCCAAATGTCCGTCAGCAGGTGAACGGACAAACCATGGTGCATCCACACA GCGGAACAAAAAACTCAGCCACAAAAATATGGATGAACTTCCGGTGCGTTTTGCTAAGTA AAAAAAAAAGCCAGGTTCAAAAAACTACGTGTTGTATGAGTCCATCTATATAATATTCTG TAAAAGGAGCAGCTACAAACGCCAAATCAGTGCCTGCTGGAGGATGGGGTGACCACATCT GTGCAATCTGACCGTAGAGGGGCAGCATGGGAATTTTTTGTCTGCAATGAAAATATTTCG TGTCTTGTTTGCGGTAGGAGATACACAACTGTATGAATTTGTCAAAACTGATAGATGTGT ATACCACAAAAAGGGACATTTTTAGATGCAAATTTAGAAAATATGAAGTAAATGGTTACT ATAATAGCAAAGACTGATGGAAGCTAGACTTCTTTGAATGTACCTTGTTTTACAAATTTG AGTTTGGAACTAAGTAAATATTTTAGATAATCATAAAAGAAAATTAAGTTTTAAAAAAGC AATCCCCCAGAACTGAAAATACAATGAAACAAATTAATGTAAATATGTTTCTAGTTGGTG GCATCAGCACTATTGCAAGTGACTTGAATACATAGTAATTTGACATTCTATCCCTAAAAA AAATTACTGCAGAAGAATGTTCACACTGTTTGCAATTATCCTATTTTTGGTGATAGTGTT GTGCTGGATATGATGATTGGGCATATAATGTGTGAGAAGGTAAATGAGTAATTAGATGAT AGTATAATTCTGTTAGCCCCAATATCCTTGAGAAGTAGGATGTTCAAACTTAGGAGAAAG TAGATACAGATACAAGATAGATATTGTATGGCTTAAGTCCGCAATAAAAAGCCTGTTGTC CTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC008840 unedited NNAGAGTTCGCATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGGTGAG GAGGGCTGTGTTTGCTTCCCCTTCTGCGATGATTCTAAGTTTTCTGAGGCCTCCCCAGCC ATGCTGAACTAGCATTGGCTGTGATGACTACTTAGGCTCCGACAAAGTCGTGGACAAATG TGGGGTGTGTGGAGGAGACAACACGGGCTGTCAGGTTGTGTCGGGCGTGTTTAAGCATGC CCTCACCAGCCTGGGCTACCACCGCGTCGTGGAGATTCCCGAGGGAGCCACGAAAATCAA CATCACGGAGATGTACAAGAGCAACAACTATTTGGCCCTGAGAAGTCGTTCTGGACGCTC CATCATCAATGGGAACTGGGCAATTGATCGACCAGGAAAATACGAGGGCGGAGGGACCAT GTTCACCTACAAGCGTCCAAATGAGATTTCGAGCACTGCCGGAGAGTCCTTTTTGGCGGA AGGTCCCACCAACGAGATCTTGGATGTCTACATGATACACCAGCAGCCAAACCCAGGCGT GCACTACGAGTACGTGATCATGGGGACCAACGCCATCAGCCCCCATGTGCCACCCCACAG GAGACCAGGGGAACCCTTCAATGGCCAGATGGTGACAGAAGGCAGGAGCCAGGATGAGGG AGAACAGAAAGGGAGGAACGAGGAGAATGAAGACTTGCGTGGGGAGGCCCCTGAGATGTT CACCTCAGAATCGGCACAGACCTTCCCAGTCAAGCATCCAGACAGATTTTCTCCCCATCG ACCGGACAACTTGGTGCCACCAGCACCGCAGCCCCCACGGCGCAGCCGGGATCACAACTG GGAGCAGCTTGGGACAACAGGAATGTCCACGACCTGTGGGAAAGGATCGCAGTACCCTAT TTTCCGCTGTG
Restriction Sites	Please inquire
ACCN	BC008840
Insert Size	2703 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	BC008840.2
RefSeq Size	2694 bp
Locus ID	79875
Gene Summary	Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN (By similarity).[UniProtKB/Swiss-Prot Function]

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