EFCAB4B (CRACR2A) (NM_032680) Human Untagged Clone
CAT＃: SC123049
EFCAB4B (untagged)-Human EF-hand calcium binding domain 4B (EFCAB4B), transcript variant 3
CNY 3656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EFCAB4B |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_032680 edited
GTCGGGCGGAGCAGGCGGCTGCTTGACAGCTGAGAGCCGAGCGGGCGGCGCGGGCAGGTC CACGGGAAGCCTACACGCCCAAGGTCATGCCCTGACCACAGCTGCCCTTCAGGAGGCTGG CACGGAGCCACCTGGGGCCATTGGGCTGTTTGTCAAGGGTGGGGCAGCAGCAACTTGCCA CTCTTCCTCCATGAGCCCAGCCAGAGCCTCCACTGGGCACTTAGCACAAGAAAAACCCTG CAGGAGCCGGATCCAGAGCGCTGGGATTCAGCAGGAGTGCCAGGAGAATTCAACACAGGT GTGCTGCCTCCTCTCCTGCCAGGTGTGTGGCTGCACAGGAGTCTTGCTGATGGTGGAATT CAAGTCACCAGTGGCCAAAGTACCCTCCAGGTGTGAAGAGTTGCAGGTCCTCCGAGGAGC CGGGAGCTGCAAGGTTCTGAAAAAGACTTCAAGAAACTGACTAATCGCGATGGCTGCCCC TGACGGGAGGGTAGTCTCCAGACCCCAGAGACTTGGTCAGGGGTCTGGCCAGGGGCCAAA GGGGAGTGGAGCCTGCCTGCATCCCCTGGACAGCCTGGAGCAGAAGGAGACTCAGGAGCA AACGTCGGGCCAGCTAGTCATGCTGAGGAAGGCACAGGAGTTCTTTCAGACCTGTGATGC TGAAGGCAAGGGCTTCATCGCCAGGAAGGATATGCAGAGGCTGCATAAGGAGCTACCGCT CAGCCTGGAGGAACTGGAGGATGTGTTTGATGCCCTGGATGCTGATGGCAATGGCTATCT GACCCCACAGGAGTTCACTACTGGATTTAGTCACTTCTTCTTCAGCCAGAATAACCCAAG TCAGGAAGATGCAGGTGAACAGGTGGCCCAGCGCCATGAAGAGAAGGTGTATCTGTCCAG AGGGGATGAGGATCTGGGCGACATGGGCGAAGATGAGGAAGCCCAGTTCCGGATGCTGAT GGACAGACTTGGAGCCCAAAAGGTGTTGGAAGATGAAAGTGATGTCAAGCAGCTCTGGTT GCAGCTGAAGAAGGAGGAACCTCATTTACTGTCCAACTTTGAAGACTTCCTGACCAGAAT CATCTCCCAGCTCCAAGAAGCCCATGAGGAGAAGAATGAACTGGAGTGTGCCCTAAAAAG GAAAATTGCTGCTTATGATGAAGAAATCCAGCATCTCTATGAGGAGATGGAACAACAAAT CAAAAGTGAGAAGGAGCAGTTTCTCCTGAAGGACACAGAGAGGTTTCAAGCCCGCAGTCA AGAGCTGGAGCAGAAACTGTTATGTAAGGAGCAGGAGCTGGAGCAGCTCACCCAGAAGCA GAAAAGGCTGGAAGGTCAGTGCACAGCCCTGCATCATGACAAGCATGAGACCAAGGCTGA GAATACCAAGCTGAAACTCACTAACCAGGAGCTGGCCCGGGAGCTGGAGCGGACTTCCTG GGAGCTCCAGGATGCTCAGCAGCAGTTGGAAAGCCTCCAGCAAGAGGCCTGCAAACTCCA CCAAGAGAAGGAGATGGAAGTGTACCGTGTGACGGAGAGTCTACAGCGTGAGAAGGCCGG GCTCCTCAAGCAGCTGGATTTCCTAAGGTGCGTCGGTGGGCACTGGCCTGTGCTGAGAGC ACCTCCCAGAAGCCTGGGGTCGGAAGGACCAGTCTGAGGGTCATCCTTGCCTACGTGCTG GAAAAACGTGCCTGCTGAGAGAGTGCCCTCAATTCCCTTGGTCCCCAGTGCAGTGTTTGG ACCACCAAGTAGCCACTCTATTATGTTTGGTCCGTTTACACATGCGCCCACATCCAGTTT ATTCCTCCTGGTGGGGAGGCTCTGCCCCACTCCTCTGAGTCCCTCACAGGACTGTGCTTG GTACTTGATCTCATGCGAGCAGAGCTGGGTTTAATGAGCATTTAATCTATGCTAGAAATA TTATCTCGTTCATTGTCAGCAAAACTGTTAGGTGAGTAGGGCAGTTCATTCACAGGAATT TACTGATGGGAAGTTGATATTAGAGGAAAGAAGTAATTTACCACAGGCGACACAGCTACT CTCTGATGGGGCCAGAATGGAAATCCGTAACTCGGCTGTGTTCTGTTCATGTTTGTTGAA TGAGTAAATGAATCACAAACAGAGCACCAAGAAAAAGCTTTCTCAGCCTTCAAAGACCCC CAGCAATAAACTCAAAGTTTACTGGTAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_032680 unedited
ACGTTCAAAATTTGTAATACGACTCACTATAGNNGGCGGCCGCGAATCGGCACGAGGGTC GGGCGGAGCAGGCGGCTGCTTGACAGCTGAGAGCCGAGCGGGCGGCGCGGGCAGGTCCAC GGGAAGCCTACACGCCCAAGGTCATGCCCTGACCACAGCTGCCCTTCAGGAGGCTGGCAC GGAGCCACCTGGGGCCATTGGGCTGTTTGTCAAGGGTGGGGCAGCAGCAACTTGCCACTC TTCCTCCATGAGCCCAGCCAGAGCCTCCACTGGGCACTTAGCACAAGAAAAACCCTGCAG GAGCCGGATCCAGAGCGCTGGGATTCAGCAGGAGTGCCAGGAGAATTCAACACAGGTGTG CTGCCTCCTCTCCTGCCAGGTGTGTGGCTGCACAGGAGTCTTGCTGATGGTGGAATTCAA GTCACCAGTGGCCAAAGTACCCTCCAGGTGTGAAGAGTTGCAGGTCCTCCGAGGAGCCGG GAGCTGCAAGGTTCTGAAAAAGACTTCAAGAAACTGACTAATCGCGATGGCTGCCCCTGA CGGGAGGGTAGTCTCCAGACCCCAGAGACTTGGTCAGGGGTCTGGCCAGGGGCCAAAGGG GAGTGGAGCCTGCCTGCATCCCCTGGACAGCCTGGAGCAGAAGGAGACTCAGGAGCAAAC GTCGGGCCAGCTAGTCATGCTGAGGAAGGCACAGGAGTTCTTTCAGACCTGTGATGCTGA AGGCAAGGGCTTCATCGCCAGGAAGGATATGCAGAGGCTGCATAAGGAGCTACCGCTCAG CCTGGNAGAACTGGGAGATGTGTTTGATGCCCTGGATGCTGATGGCAATGGCTATCTGAC CCACAGGAGTTCACTACTGGATTTAGTCACTTCTTNCTCAGCCAGAATAACCCAGTCAGG AAGATGCANGTGAACAGGTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_032680 |
| Insert Size | 2213 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_032680.2, NP_116069.1 |
| RefSeq Size | 2204 bp |
| RefSeq ORF | 1188 bp |
| Locus ID | 84766 |
| UniProt ID | Q9BSW2 |
| Gene Summary | Ca(2+)-binding protein that plays a key role in store-operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+) concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+) resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (c) has a shorter and distinct C-terminus, compared to isoform a. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219097 | EFCAB4B (Myc-DDK-tagged)-Human EF-hand calcium binding domain 4B (EFCAB4B), transcript variant 3 |
CNY 3656.00 |
|
| RC219097L1 | Lenti ORF clone of Human EF-hand calcium binding domain 4B (EFCAB4B), transcript variant 3, Myc-DDK-tagged |
CNY 6056.00 |
|
| RC219097L2 | Lenti ORF clone of Human EF-hand calcium binding domain 4B (EFCAB4B), transcript variant 3, mGFP tagged |
CNY 5890.00 |
|
| RC219097L3 | Lenti ORF clone of Human EF-hand calcium binding domain 4B (EFCAB4B), transcript variant 3, Myc-DDK-tagged |
CNY 5890.00 |
|
| RC219097L4 | Lenti ORF clone of Human EF-hand calcium binding domain 4B (EFCAB4B), transcript variant 3, mGFP tagged |
CNY 5890.00 |
|
| RG219097 | EFCAB4B (tGFP-tagged) - Human EF-hand calcium binding domain 4B (EFCAB4B), transcript variant 3 |
CNY 5256.00 |
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