PPIL5 (LRR1) (BC030142) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	4-1BB-mediated signaling molecule; 4-1BBLRR; cyclophilin-like 5; LRR-1; LRR-repeat protein 1; MGC20689; peptidylprolyl isomerase (cyclophilin)-like 5; peptidylprolyl isomerase (cyclophilin)-like 5, isoform 3
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC030142 edited GGCACGAGGCCGGGCGCGAGCCCGGATCCAGGTGGTCAGTCCCGGTACGCAACCACGGCG AGAACCCGGCCCTGCTAAGGGAGAAGGGAAGCCGTTTCCCGCGGGCTTCATACAGACACG GTGCTAAGACAGCCCGAGTCGCGGACCAGTCCAACAGGCAGGCAGATCAGTGGGCAGCCC GCGTGCGCGAGGACCCCGATGGCGGCGCCGGGTGGCGGGAAGGAGGAAGTTTCAAAGCCA GCTTGACCTGGTTGTGGCCGTTGGGCGAGATGAAGCTACACTGTGAGGTGGAGGTGATCA GCCGGCACTTGCCCGCCTTGGGGCTTAGGAACCGGGGCAAGGGCGTCCGAGCCGTGTTGA GCCTCTGTCAGCAGACTTCCAGGAGTCAGCCGCCGGTCCGAGCCTTCCTGCTCATCTCCA CCCTGAAGGACAAGCGCGGGACCCGCTATGAGCTAAGGGAGAACATTGAGCAATTCTTCA CCAAATTTGTAGATGAGGGGAAAGCCACTGTTCGGTTAAAGGAGCCTCCTGTGGATATCT GTCTAAGTAAGGATTCCATATGGCTCTCATATCATTCCATTCCATCTCTGCCAAGATTTG GATACCGCAAAAATTTGTGTTTGTGGAAGATTCTGTCTGAACTCTTTCATTCAAGGAACT ACTACCATGAATCTGCATTCTGTTGCCCACACTGTGGTCTTAGTAGATAATTTGGGTGGT ACTGAAGCACCTATTATCTCTTATTTCTGTTCTCTAGGCTGTTATGTTAATTCCTCTGAT ATGTTAAAGTAATGGGTGAGACCAGAAAAAGAAATTTCAATAACAGATCAGTTTGGGGTG CATGTATGATTTTGCAGCGTCAAATTGGAGTAAGGGAAGATTTCTGTATACTTGCTGGAG AGGAGGAATGTGTATAGTTACTCATTTAGATGACTCCAAAACTTTTATTAAAACCAATTT TAGTTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC030142 unedited TTTTNNNATGTCTATTGTATCGATCCTTAGGCGCCGCGATTCGCCGGGCCGGCGCGGCCC GGTCCAGTGGTCAGTCCCGGTACGCAACCACGGCGAGAACCCGGCCCTGCTAAGGGAGAA GGGAAGCCGTTTCCCGCGGGCTTCATACAGACACGGTGCTAAGACAGCCCGAGTCGCGGA CCAGTCCAACAGGCAGGCAGATCAGTGGGCAGCCCGCGTGCGCGAGGACCCCGATGGCGG CGCCGGGTGGCGGGAAGGAGGAAGTTTCAAAGCCAGCTTGACCTGGTTGTGGCCGTTGGG CGAGATGAAGCTACACTGTGAGGTGGAGGTGATCAGCCGGCACTTGCCCGCCTTGGGGCT TAGGAACCGGGGCAAGGGCGTCCGAGCCGTGTTGAGCCTCTGTCAGCAGACTTCCAGGAG TCAGCCGCCGGTCCGAGCCTTCCTGCTCATCTCCACCCTGAAGGACAAGCGCGGGACCCG CTATGAGCTAAGGGAGAACATTGAGCAATTCTTCACCAAATTTGTAGATGAGGGGAAAGC CACTGTTCGGTTAAAGGAGCCTCCTGTGGATATCTGTCTAAGTAAGGATTCCATATGGCT CTCATATCATTCCATTCCATCTCTGCCAAGATTTGGATACCGCAAAAATTTGTGTTTGTG GAAGATTCTGTCTGAACTCTTTCATTCAAGGAACTACTACCATGAATCTGCATTCTGTTG CCCACACTGTGGTCTTAGTAGATAATTTGGGTGGTACTGAAGCACCTATTATCTCTTATT TCTGTTCTCTAGGCTGTTATGTTAATTCCTCTGATATGTTAAAGTAATGGGGTGAGACCA GG
Restriction Sites	Please inquire
ACCN	BC030142
Insert Size	999 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	BC030142.1, AAH30142.1
RefSeq Size	999 bp
Locus ID	122769
Protein Families	Druggable Genome
Gene Summary	The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]

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