PTP alpha (PTPRA) (NM_080840) Human Untagged Clone
CAT＃: SC120329
PTPRA (untagged)-Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 2
CNY 5816.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HEPTP; HLPR; HPTPA; HPTPalpha; LRP; PTPA; PTPRL2; R-PTP-alpha; RPTPA |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC120329 sequence for NM_080840 edited (data generated by NextGen Sequencing)
ATGGATTCCTGGTTCATTCTTGTTCTGCTCGGCAGTGGTCTGATATGTGTCAGTGCCAAC AATGCTACCACAGTTGCACCTTCTGTAGGAATTACAAGATTAATTAACTCATCAACGGCA GAACCAGTTAAAGAAGAGGCCAAAACTTCAAATCCAACTTCTTCACTAACTTCTCTTTCT GTGGCACCAACATTCAGCCCAAATATAACTCTGGGACCCACCTATTTAACCACTGTCAAT TCTTCAGACTCTGACAATGGGACCACAAGAACAGCAAGCACCAATTCTATAGGCATTACA ATTTCACCAAATGGAACGTGGCTTCCAGATAACCAGTTCACGGATGCCAGAACAGAACCC TGGGAGGGGAATTCCAGCACCGCAGCAACCACTCCAGAAACTTTCCCTCCTTCAGATGAG ACACCAATTATTGCGGTGATGGTGGCCCTGTCCTCTCTGCTAGTGATCGTGTTTATTATC ATAGTTTTGTACATGTTAAGGTTTAAGAAATACAAGCAAGCTGGGAGCCATTCCAATTCT TTCCGCTTATCCAACGGCCGCACTGAGGATGTGGAGCCCCAGAGTGTGCCACTTCTGGCC AGATCCCCAAGCACCAACAGGAAATACCCACCCCTGCCCGTGGACAAGCTGGAAGAGGAA ATTAACCGGAGAATGGCAGACGACAATAAGCTCTTCAGGGAGGAATTCAACGCTCTCCCT GCATGTCCTATCCAGGCCACCTGTGAGGCTGCTTCCAAGGAGGAAAACAAGGAAAAAAAT CGATATGTAAACATCTTGCCTTATGACCACTCTAGAGTCCACCTGACACCGGTTGAAGGG GTTCCAGATTCTGATTACATCAATGCTTCATTCATCAACGGCTACCAAGAAAAGAACAAA TTCATTGCTGCACAAGGACCAAAAGAAGAAACGGTGAATGATTTCTGGCGGATGATCTGG GAACAAAACACAGCCACCATCGTCATGGTTACCAACCTGAAGGAGAGAAAGGAGTGCAAG TGCGCCCAGTACTGGCCAGACCAAGGCTGCTGGACCTATGGGAATATTCGGGTGTCTGTA GAGGATGTGACTGTCCTGGTGGACTACACAGTACGGAAGTTCTGCATCCAGCAGGTGGGC GACATGACCAACAGAAAGCCACAGCGCCTCATCACTCAGTTCCACTTTACCAGCTGGCCA GACTTTGGGGTGCCTTTTACCCCGATCGGCATGCTCAAGTTCCTCAAGAAGGTGAAGGCC TGTAACCCTCAGTATGCAGGGGCCATCGTGGTCCACTGCAGTGCAGGTGTAGGGCGTACA GGTACCTTTGTCGTCATTGATGCCATGCTGGACATGATGCATACAGAACGGAAGGTGGAC GTGTATGGCTTTGTGAGCCGGATCCGGGCACAGCGCTGCCAGATGGTGCAAACCGATATG CAGTATGTCTTCATATACCAAGCCCTTCTGGAGCATTATCTCTATGGAGATACAGAACTG GAAGTGACCTCTCTAGAAACCCACCTGCAGAAAATTTACAACAAAATCCCAGGGACCAGC AACAATGGATTAGAGGAGGAGTTTAAGAAGTTAACATCAATCAAAATCCAGAATGACAAG ATGCGGACTGGAAACCTTCCAGCCAACATGAAGAAGAACCGTGTTTTACAGATCATTCCA TATGAATTCAACAGAGTGATCATTCCAGTTAAGCGGGGCGAAGAGAATACAGACTATGTG AACGCATCCTTTATTGATGGCTACCGGCAGAAGGACTCCTATATCGCCAGCCAGGGCCCT CTTCTCCACACAATTGAGGACTTCTGGCGAATGATCTGGGAGTGGAAATCCTGCTCTATC GTGATGCTAACAGAACTGGAGGAGAGAGGCCAGGAGAAGTGTGCCCAGTACTGGCCATCT GATGGACTGGTGTCCTATGGAGATATTACAGTGGAACTGAAGAAGGAGGAGGAATGTGAG AGCTACACCGTCCGAGACCTCCTGGTCACCAACACCAGGGAGAATAAGAGCCGGCAGATC CGGCAGTTCCACTTCCATGGCTGGCCTGAAGTGGGCATCCCCAGTGACGGAAAGGGCATG ATCAGCATCATCGCCGCCGTGCAGAAGCAGCAGCAGCAGTCAGGGAACCACCCCATCACC GTGCACTGCAGCGCCGGGGCAGGAAGGACGGGGACCTTCTGTGCCCTGAGCACCGTCCTG GAGCGTGTGAAAGCAGAGGGGATTTTGGATGTCTTCCAGACTGTCAAGAGCCTGCGGCTA CAGAGGCCACACATGGTCCAGACACTGGAACAGTATGAGTTCTGCTACAAGGTGGTGCAG GAGTATATTGATGCATTCTCAGATTATGCCAACTTCAAGTAA Clone variation with respect to NM_080840.2 >OriGene 5' read for NM_080840 unedited
GTCAACATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCGGCCCGAAC GCCGCCGCGGAGCCGAGGCGGAGCCGCTGTCCTCGTCCCCAGCGGTCCCGCCCAACGCCC GACTCTGTGACACAACTNAAAAAAAAACAAAGGTATTTATGGAATTCCACTGAGTGGTAA TGGATGATGCAGTTCAAATAACTAAGGACACATGTTCAAAGAGCATAATTAACTTTTTAA AAGAAGCTAATAAGCATGGATTCCTGGTTCATTCTTGTTCTGCTCGGCAGTGGTCTGATA TGTGTCAGTGCCAACAATGCTACCACAGTTGCACCTTCTGTAGGAATTACAAGATTAATT AACTCATCAACGGCAGAACCAGTTAAAGAAGAGGCCAAAACTTCAAATCCAACTTCTTCA CTAACTTCTCTTTCTGTGGCACCAACATTCAGCCCAAATATAACTCTGGGACCCACCTAT TTAACCACTGTCAATTCTTCAGACTCTGACAATGGGACCACAAGAACAGCAAGCACCAAT TCTATAGGCATTACAATTTCACCAAATGGAACGTGGCTTCCAGATAACCAGTTCACGGAT GCCAGAACAGAACCCTGGGAGGGGAATTCCAGCACCGCAGCAACCACTCCAGAAACTTTC CCTCCTTCAGATGAGACACCAATTATTGCGGTGATGGTGGCCCTGTCCTCTCTGCTAGTG ATCGTGTTTATTATCATAGTTNTGTACATGTTAAGGTTTAAGAAATACAAGCAAGCTGGG AGCCATTCCAATTCTTTCCGCTTATCCAAACGCCGCACTGANGATGTGNAGCCCCAGATG TGCCACTTCTGGCCAGATCCCCAGCACCACAGGAAATACCACCCCTGCCCGTGGACAGCT GGAAGAGAAAATACCGNAGATGGCAGAG >OriGene 3' read for NM_080840 unedited
NNAATTACTTTGNNACCGCGGCCGCATTCTANGATCGAGTTTTTTTTTTTTTTTTTTTTT TCAGGGAGTCAAAGCTTTTATTACCTGATAGTCCCTAGTGTGGTGCCAGAGATACCGCTC TGGTCCTATTACTCCCCATGATATCAGTGGTGGGGATGGGGGAGGGGACCAGGGAGAGAG GGGAGGGATATTTACAGTGCATGGTGGTACGGGGACAACCACTTTCCTCGAGAGCTCTGA GAACTTTGTGCTTTTTTTCTTAGTTGGTGCCGAGCTACCTGGAATGGATTTTGTGTTTAT CTTCTTTAGGGAAAGATGTATTAACCAAAGCACAATCCAGCCCAATTTCTCGGCTGAGGA TTTCACGATATCAATCCAAACATCACACTATTTAATTCCCCAATAAAACATTGGAAAAAG GACTATCAGTGCTAACACATTTACATATAAAATTTCCACCTAATAGGTAATAGAAGCCTA TGTACCAATTTCTAAAACAGTTATAAGATATATACACAATTTGGGGTATATTAACAAAAC AGAATATTACAAAATATTAAAGGCAATCCTCCTGGTCCACGGACCCTTGTTGCCGCTTAC TTGAAGTTGGCATAATCTGAGAATGCATCAATATACTCCTGCACCACCTTGTAGCAGAAC TCATACTGTTCCAGTGTCTGGACCATGTGTGGCCTCTGTAGCCGCAGGCTCTTGACAGTC TGGAAGACATCCAAAATCCCCTCTGCTTTCACACGCTCCNAGACGGTGCTCANGGCACAG AAGGGTCCCCGTCCTTCCTGCCCCCGCGCTGCAGTGCACGGTGATGGGGGNGGGTTCCCT GACTGCTGCTGCTGCTTCTGCACGGCGGCGATGATGCTGATCATCCCTTTNCGTACTGGG GGATGCCACTTCAGCCAGCATGGAAGTGGACTGNNCGATCTGCGGCTCTATT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_080840 |
| Insert Size | 3050 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_080840.1, NP_543030.1 |
| RefSeq Size | 3279 bp |
| RefSeq ORF | 2382 bp |
| Locus ID | 5786 |
| UniProt ID | P18433 |
| Domains | Y_phosphatase, PTPc_motif |
| Protein Families | Druggable Genome, Phosphatase, Transmembrane |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) contains an alternate 5' UTR exon, and lacks an internal coding exon, when compared to variant 1. The resulting isoform (2) lacks a 9 aa internal segment, as compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223746 | PTPRA (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 2 |
CNY 5808.00 |
|
| RC223746L3 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 2, Myc-DDK-tagged |
CNY 7700.00 |
|
| RC223746L4 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 2, mGFP tagged |
CNY 7700.00 |
|
| RG223746 | PTPRA (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 2 |
CNY 6370.00 |
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