TBX5 (NM_000192) Human Untagged Clone
CAT＃: SC120046
TBX5 (untagged)-Human T-box 5 (TBX5), transcript variant 1
CNY 3864.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HOS |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC120046 sequence for NM_000192 edited (data generated by NextGen Sequencing)
ATGGCCGACGCAGACGAGGGCTTTGGCCTGGCGCACACGCCTCTGGAGCCTGACGCAAAA GACCTGCCCTGCGATTCGAAACCCGAGAGCGCGCTCGGGGCCCCCAGCAAGTCCCCGTCG TCCCCGCAGGCCGCCTTCACCCAGCAGGGCATGGAGGGAATCAAAGTGTTTCTCCATGAA AGAGAACTGTGGCTAAAATTCCACGAAGTGGGCACGGAAATGATCATAACCAAGGCTGGA AGGCGGATGTTTCCCAGTTACAAAGTGAAGGTGACGGGCCTTAATCCCAAAACGAAGTAC ATTCTTCTCATGGACATTGTACCTGCCGACGATCACAGATACAAATTCGCAGATAATAAA TGGTCTGTGACGGGCAAAGCTGAGCCCGCCATGCCTGGCCGCCTGTACGTGCACCCAGAC TCCCCCGCCACCGGGGCGCATTGGATGAGGCAGCTCGTCTCCTTCCAGAAACTCAAGCTC ACCAACAACCACCTGGACCCATTTGGGCATATTATTCTAAATTCCATGCACAAATACCAG CCTAGATTACACATCGTGAAAGCGGATGAAAATAATGGATTTGGCTCAAAAAATACAGCG TTCTGCACTCACGTCTTTCCTGAGACTGCGTTTATAGCAGTGACTTCTTACCAGAACCAC AAGATCACGCAATTAAAGATTGAGAATAATCCCTTTGCCAAAGGATTTCGGGGCAGTGAT GACATGGAGCTGCACAGAATGTCAAGAATGCAAAGTAAAGAATATCCCGTGGTCCCCAGG AGCACCGTGAGGCAAAAAGTGGCCTCCAACCACAGTCCTTTCAGCAGCGAGTCTCGAGCT CTCTCCACCTCATCCAATTTGGGGTCCCAATACCAGTGTGAGAATGGTGTTTCCGGCCCC TCCCAGGACCTCCTGCCTCCACCCAACCCATACCCACTGCCCCAGGAGCATAGCCAAATT TACCATTGTACCAAGAGGAAAGAGGAAGAATGTTCCACCACAGACCATCCCTATAAGAAG CCCTACATGGAGACATCACCCAGTGAAGAAGATTCCTTCTACCGCTCTAGCTATCCACAG CAGCAGGGCCTGGGTGCCTCCTACAGGACAGAGTCGGCACAGCGGCAAGCTTGCATGTAT GCCAGCTCTGCGCCCCCCAGCGAGCCTGTGCCCAGCCTAGAGGACATCAGCTGCAACACG TGGCCAAGCATGCCTTCCTACAGCAGCTGCACCGTCACCACCGTGCAGCCCATGGACAGG CTACCCTACCAGCACTTCTCCGCTCACTTCACCTCGGGGCCCCTGGTCCCTCGGCTGGCT GGCATGGCCAACCATGGCTCCCCACAGCTGGGAGAGGGAATGTTCCAGCACCAGACCTCC GTGGCCCACCAGCCTGTGGTCAGGCAGTGTGGGCCTCAGACTGGCCTGCAGTCCCCTGGC ACCCTTCAGCCCCCTGAGTTCCTCTACTCTCATGGCGTGCCAAGGACTCTATCCCCTCAT CAGTACCACTCTGTGCACGGAGTTGGCATGGTGCCAGAGTGGAGCGACAATAGCTAA Clone variation with respect to NM_000192.3 648 c=>t >OriGene 5' read for NM_000192 unedited
CCGACACTCGTCATTTTGTNAATACGNACTTTCTNTNAGGGNNCGGCCGCGNAATTTCGG CACCAGGATAAACAGTAATATTTAATTTGTCGGAGACCACAAACCAACCTTGAGCTGGGA GGTACGTGCTCTTCTTGACAGACGTTGGAAGAAGACCTGGCCTAAAGAGGTCTCTTTTGG TGGTCCTTTTCAAAGTCTTCACCTGAGCCCTGCTCTCCAGCGAGGCGCACTCCTGGCTTT TGCGCTCCAAAGAAGAGGTGGGATAGTTGGAGAGCAGAACCTTGCGCGGGCACAGGGCCC TGGGCGCACCATGGCCGACGCAGACGAGGGCTTTGGCCTGGCGCACACGCCTCTGGAGCC TGACGCAAAAGACCTGCCCTGCGATTCGAAACCCGAGAGCGCGCTCGGGGCCCCCAGCAA GTCCCCGTCGTCCCCGCAGGCCGCCTTCACCCAGCAGGGCATGGAGGGAATCAAAGTGTT TCTCCATGAAAGAGAACTGTGGCTAAAATTCCACGAAGTGGGCACGGAAATGATCATAAC CAAGGCTGGAAGGCGGATGTTTCCCAGTTACAAAGTGAAGGTGACGGGCCTTAATCCCAA AACGAAGTACATTCTTCTCATGGACATTGTACCTGCCGACGATCACAGATACAAATTCGC AGATAATAAATGGTCTGTGACGGGCAAAGCTGAGCCCGCCATGCCTGGCCGCCTGTACGT GCACCCAGACTCCCCCGCCACCGGGGCGCATTGGATGAAGCAGCTCGTCTCCTTCCCAGA AACTCAGCTCACCACAACCACCTGGACCCTTTGGGCATATTATTCTAAATTCATGCANCA ATACCAGCCTAGATTACACATCGTGAAAGCGGATGAAAATATGGATTNGNCTCAAAAATA CACCGTCT >OriGene 3' read for NM_000192 unedited
GGAAAAAAACAATATATTAACAAAAAAACACAAACTTGGTTTCTGAGTATCAATAAAATT AAAAGCTCTTGGCCAGCTCCTATGCTGGGTTTCATTTCATGTTATTACTTAATTAGAATT CCTATTTATAAATAAATAGTACCAGTAAAATATTACATCTGAAGAACCCTACCATAACAC TTTACTTACACACTTTTTCCAATACTGTTTTCGGCTTTCAGTAAACACAGTTCTGTGTCG GCATTGGTGTGGGCGTGGTTTCTTTGGCGAGATATCATTGCCGACTGTGCCCTGTCTCTT CTGTAGGAACCGTGTATTTTGCTTGACATCCACTTTGCCCCGTTTTTCACGGACGTTTGG AACGCTGGTTCCTGCCCTGTTTCCTCCTAACACATGCCTCTTTTATTAATAACCCCATTT CGGTTTTTCCGTCTCAACTCTTCCCACACCCTTCTCGCCCCTGCCATTACATTCCTGCCG CACCGTCCACCGCGTTTCTTTCCTCTCGCCCATTTCCGCCTTTCCCCCCTTTTTTTTCTT TTCTCCCCCCCCCCCGACAGGCATTTTTTCAGTCTTTCCCGCGCTTTCCGGCGTCGCCCT TTTTTTCCCCCCTTCTCCTTTTTCCCGTATCGGGCCCCCTCCTTTTCCCGCCGTTTTCCC CCCGCCATTTTTTGGTTTTTTTTTTTCGCGCCCCCGCGTTGTGCAAAACCCGCTCTCTCC CCCCCCTTTTTTCTCGTTGTTTTTTTCTCCCCCCTCTTTTTTCTCCTCTTGTTTTTTGTG TCCACGTTTTCCGAATTGCCCTCGTCACCCGCCGGCTCTGCCGGCCCCTTTTTTTTTTTT TCGCCCCCTTTTTTCCCCCTCCCCCCCGTCTTTTGT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000192 |
| Insert Size | 1557 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000192.3, NP_000183.2 |
| RefSeq Size | 3921 bp |
| RefSeq ORF | 1557 bp |
| Locus ID | 6910 |
| UniProt ID | Q99593 |
| Domains | T-box |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1 and 4 both encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Deciphering Transcriptional Networks during Human Cardiac Development
,null,
Cells
,PubMed ID 36497174
[TBX5]
|
|
A TBX5 3'UTR variant increases the risk of congenital heart disease in the Han Chinese population
,Wang, F;Liu, D;Zhang, RR;Yu, LW;Zhao, JY;Yang, XY;Jiang, SS;Ma, D;Qiao, B;Zhang, F;Jin, L;Gui, YH;Wang, HY;,
Cell Discov
,PubMed ID 28761722
[TBX5]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216520 | TBX5 (Myc-DDK-tagged)-Human T-box 5 (TBX5), transcript variant 1 |
CNY 5784.00 |
|
| RC216520L1 | Lenti ORF clone of Human T-box 5 (TBX5), transcript variant 1, Myc-DDK-tagged |
CNY 8184.00 |
|
| RC216520L2 | Lenti ORF clone of Human T-box 5 (TBX5), transcript variant 1, mGFP tagged |
CNY 8184.00 |
|
| RC216520L3 | Lenti ORF clone of Human T-box 5 (TBX5), transcript variant 1, Myc-DDK-tagged |
CNY 5890.00 |
|
| RC216520L4 | Lenti ORF clone of Human T-box 5 (TBX5), transcript variant 1, mGFP tagged |
CNY 8184.00 |
|
| RG216520 | TBX5 (tGFP-tagged) - Human T-box 5 (TBX5), transcript variant 1 |
CNY 7384.00 |
