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Lipoprotein lipase (LPL) (NM_000237) Human Untagged Clone
CAT＃: SC120026
LPL (untagged)-Human lipoprotein lipase (LPL)
CNY 2,950.00
| Cited in 3 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HDLCQ11; LIPD |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC120026 sequence for NM_000237 edited (data generated by NextGen Sequencing)
ATGGAGAGCAAAGCCCTGCTCGTGCTGACTCTGGCCGTGTGGCTCCAGAGTCTGACCGCC TCCCGCGGAGGGGTGGCCGCCGCCGACCAAAGAAGAGATTTTATCGACATCGAAAGTAAA TTTGCCCTAAGGACCCCTGAAGACACAGCTGAGGACACTTGCCACCTCATTCCCGGAGTA GCAGAGTCCGTGGCTACCTGTCATTTCAATCACAGCAGCAAAACCTTCATGGTGATCCAT GGCTGGACGGTAACAGGAATGTATGAGAGTTGGGTGCCAAAACTTGTGGCCGCCCTGTAC AAGAGAGAACCAGACTCCAATGTCATTGTGGTGGACTGGCTGTCACGGGCTCAGGAGCAT TACCCAGTGTCCGCGGGCTACACCAAACTGGTGGGACAGGATGTGGCCCGGTTTATCAAC TGGATGGAGGAGGAGTTTAACTACCCTCTGGACAATGTCCATCTCTTGGGATACAGCCTT GGAGCCCATGCTGCTGGCATTGCAGGAAGTCTGACCAATAAGAAAGTCAACAGAATTACT GGCCTCGATCCAGCTGGACCTAACTTTGAGTATGCAGAAGCCCCGAGTCGTCTTTCTCCT GATGATGCAGATTTTGTAGACGTCTTACACACATTCACCAGAGGGTCCCCTGGTCGAAGC ATTGGAATCCAGAAACCAGTTGGGCATGTTGACATTTACCCGAATGGAGGTACTTTTCAG CCAGGATGTAACATTGGAGAAGCTATCCGCGTGATTGCAGAGAGAGGACTTGGAGATGTG GACCAGCTAGTGAAGTGCTCCCACGAGCGCTCCATTCATCTCTTCATCGACTCTCTGTTG AATGAAGAAAATCCAAGTAAGGCCTACAGGTGCAGTTCCAAGGAAGCCTTTGAGAAAGGG CTCTGCTTGAGTTGTAGAAAGAACCGCTGCAACAATCTGGGCTATGAGATCAATAAAGTC AGAGCCAAAAGAAGCAGCAAAATGTACCTGAAGACTCGTTCTCAGATGCCCTACAAAGTC TTCCATTACCAAGTAAAGATTCATTTTTCTGGGACTGAGAGTGAAACCCATACCAATCAG GCCTTTGAGATTTCTCTGTATGGCACCGTGGCCGAGAGTGAGAACATCCCATTCACTCTG CCTGAAGTTTCCACAAATAAGACATACTCCTTCCTAATTTACACAGAGGTAGATATTGGA GAACTACTCATGTTGAAGCTCAAATGGAAGAGTGATTCATACTTTAGCTGGTCAGACTGG TGGAGCAGTCCCGGCTTCGCCATTCAGAAGATCAGAGTAAAAGCAGGAGAGACTCAGAAA AAGGTGATCTTCTGTTCTAGGGAGAAAGTGTCTCATTTGCAGAAAGGAAAGGCACCTGCG GTATTTGTGAAATGCCATGACAAGTCTCTGAATAAGAAGTCAGGCTGA Clone variation with respect to NM_000237.2 1164 c=>a >OriGene 5' read for NM_000237 unedited
TTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGTCCCCCTCTTCCT CCTCCTCAAGGGAAAGCTGCCCACTTCTAGCTGCCCTGCCATCCCCTTTAAAGGGCGACT TGCTCAGCGCCAAACCGCGGCTCCAGCCCTCTCCAGCCTCCGGCTCAGCCGGCTCATCAG TCGGTCCGCGCCTTGCAGCTCCTCCAGAGGGACGCGCCCCGAGATGGAGAGCAAAGCCCT GCTCGTGCTGACTCTGGCCGTGTGGCTCCAGAGTCTGACCGCCTCCCGCGGAGGGGTGGC CGCCGCCGACCAAAGAAGAGATTTTATCGACATCGAAAGTAAATTTGCCCTAAGGACCCG TGAAGACACAGCTGAGGACACTTGCCACCTCATTCCCGGAGTAGCAGAGTCCGTGGCTAC CTGTCATTTCAATCACAGCAGCAAAACCTTCATGGTGATCCATGGCTGGACGGTAACAGG AATGTATGAGAGTTGGGTGCCAAAACTTGTGGCCGCCCTGTACAAGAGAGAACCAGACTC CAATGTCATTGTGGTGGACTGGCTGTCACGGGCTCAGGAGCATTACCCAGTGTCCGCGGG CTACACCAAACTGGTGGGACAGGATGTGGCCCGGTTTATCAACTGGATGGAGGAGGAGTT TAACTACCCTCTGGACAATGTCCATCTCTTGGGATACAGCCTTGGAGCCCATGCTGCTGG CATTGCAAGAAGTCTGACCAATAAGAAAGTCAACAGAATTACTGGCCTCGATCCAGCTGG ACCCTACTTTGAGTATGCAGAAGCCCCGAGTCGTCTTTCTCCTGATGATGCAGATTTGGT AGACGTCTTACACACTTTCACCAGAGGTCCCCTGGTCGAGCATGGAATCCAGAACN >OriGene 3' read for NM_000237 unedited
TGGACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTGGGGGAATAA AATGTTGTCAATTTTATTAAAAGCTGATTCCATTTCTTCACACAGTTAAGTACGTTTCTT TCTTGTTTTGTTAAAGCCCATTTCATAAGATTAAGTTGGCTCTGTGAGACCATCACTGAT AAAGACACATACAGTTAGCACCACACATTTATAAATGCAGATAGCCACAATGACCTTTCC AATATGTACAAGCTCCATTTACACATCCACACATGTATTTACAGCTAATAAATAAAATGT AAAGCCAGAACATCCTTGATATATATAGCAAAGTTTTTCGGAGCCAGAGTTCCCAGTGCT ATGTGCTGCTTTAGTGAATCTTTTAAGTTAATGCACCCTGGGTCACAACCCAAATCCAGA AATTTAATGAATTAATAAAGGGGATGCCAACAACAAATCATACATCATTTTATTTTTAGA GAGAATTCATTCCAAGCCTGATGATGTTAATCACAACATTGGTCCTACTATTTATAGGCA CGATCATCTCTCTCAGAGAAAGGGTCGAAGTTCTGGCACATCAGGAACAATTTCTACTCC GACATGTTCCAATACATCCCTTGATCGACTGTTTTCCCTTCCGAATTATGCTGAAGGACA ACACACATGCAGAGCTTTCTAGTATGTGTTCAGATATCACATACTTTCACAGTCGGGTTC CCAGCTATAGCCTCTGAGAATTTGACATCTTTATCATTTCATATTTATACGTAGAAGAGC ATTCTGAAAAATAGGAGATCTAGNTTATAAANTAGTGGTCACTCACTCCTGATATAGTGN TAAAAACAAACAATTACACCCTCATGGTACTNCATCTGGCTCATTGCACGCGATGGTTTA CAAGCACTGCTTAGGAACCACCCCAGGAACTTTTCCACCTTN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000237 |
| Insert Size | 3670 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000237.1, NP_000228.1 |
| RefSeq Size | 3549 bp |
| RefSeq ORF | 1428 bp |
| Locus ID | 4023 |
| UniProt ID | P06858 |
| Domains | lipase, PLAT |
| Protein Families | Druggable Genome |
| Protein Pathways | Alzheimer's disease, Glycerolipid metabolism, PPAR signaling pathway |
| Gene Summary | LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Severe hypertriglyceridemia due to two novel loss-of-function lipoprotein lipase gene mutations (C310R/E396V) in a Chinese family associated with recurrent acute pancreatitis
,Lun, Y;Sun, X;Wang, P;Chi, J;Hou, X;Wang, Y;,
Oncotarget
,PubMed ID 28548960
[LPL]
|
|
Over-Expression of Human Lipoprotein Lipase in Mouse Mammary Glands Leads to Reduction of Milk Triglyceride and Delayed Growth of Suckling Pups
,null,
PLoS ONE
,PubMed ID 21698114
[LPL]
|
|
A novel fluorogenic substrate for the measurement of endothelial lipase activity
,Andrew L. Darrow, Matthew W. Olson, Hong Xin, Sharon L. Burke, Charles Smith, Celine Schalk-Hihi, Robyn Williams, Shariff S. Bayoumy, Ingrid C. Deckman, Matthew J. Todd, Bruce P. Damiano, and Margery A. Connelly,
J. Lipid Res., Feb 2011; 52: 374 - 382
[LPL]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203766 | LPL (Myc-DDK-tagged)-Human lipoprotein lipase (LPL) |
CNY 5,488.00 |
|
| RC203766L1 | Lenti ORF clone of Human lipoprotein lipase (LPL), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC203766L2 | Lenti ORF clone of Human lipoprotein lipase (LPL), mGFP tagged |
CNY 5,890.00 |
|
| RC203766L3 | Lenti ORF clone of Human lipoprotein lipase (LPL), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC203766L4 | Lenti ORF clone of Human lipoprotein lipase (LPL), mGFP tagged |
CNY 7,888.00 |
|
| RG203766 | LPL (tGFP-tagged) - Human lipoprotein lipase (LPL) |
CNY 7,088.00 |
|
| SC322258 | LPL (untagged)-Human lipoprotein lipase (LPL) |
CNY 2,950.00 |
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