United States
Germany
Japan
United Kingdom
China
NDP (NM_000266) Human Untagged Clone
CAT＃: SC120005
NDP (untagged)-Human Norrie disease (pseudoglioma) (NDP)
CNY 1,800.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EVR2; FEVR; ND |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC120005 sequence for NM_000266 edited (data generated by NextGen Sequencing)
ATGAGAAAACATGTACTAGCTGCATCCTTTTCTATGCTCTCCCTGCTGGTGATAATGGGA GATACAGACAGTAAAACGGACAGCTCATTCATAATGGACTCGGACCCTCGACGCTGCATG AGGCACCACTATGTGGATTCTATCAGTCACCCATTGTACAAGTGTAGCTCAAAGATGGTG CTCCTGGCCAGGTGCGAGGGGCACTGCAGCCAGGCGTCACGCTCCGAGCCTTTGGTGTCG TTCAGCACTGTCCTCAAGCAACCCTTCCGTTCCTCCTGTCACTGCTGCCGGCCCCAGACT TCCAAGCTGAAGGCACTGCGGCTGCGATGCTCAGGGGGCATGCGACTCACTGCCACCTAC CGGTACATCCTCTCCTGTCACTGCGAGGAATGCAATTCCTGA Clone variation with respect to NM_000266.3 >OriGene 5' read for NM_000266 unedited
TCAGAATTTTGTAATACGAACTCACTATAGGGCGGCCGCGAATTCGCACGAGGCTTAAAC AACAGTCCTAACTTTTGTGTGTTGCAAATATAAAAGGCAAGCCATGTGACAGAGGGACAG AAGAACAAAAGCATTTGGAAGTAACAGGACCTCTTTCTAGCTCTCAGAAAAGTCTGAGAA GAAAGGAGCCCTGCGTTCCCCTAAGCTGTGCAGCAGATACTGTGATGATGGATTGCAAGT GCAAAGAGTAAGACAAAACTCCAGCACATAAAGGACAATGACAACCAGAAAGCTTCAGCC CGATCCTGCCCTTTCCTTGAACGGGACTGGATCCTAGGAGGTGAAGCCATTTCCAATTTT TTGTCCTCTGCCTCCCTCTGCTGTTCTTCTAGAGAAGTTTTTCCTTACAACAATGAGAAA ACATGTACTAGCTGCATCCTTTTCTATGCTCTCCCTGCTGGTGATAATGGGAGATACAGA CAGTAAAACGGACAGCTCATTCATAATGGACTCGGACCCTCGACGCTGCATGAGGCACCA CTATGTGGATTCTATCAGTCACCCATTGTACAAGTGTAGCTCAAAGATGGTGCTCCTGGC CAGGTGCGAGGGGCACTGCAGCCAGGCGTCACGCTCCGAGCCTTTGGTGTCGTTCAGCAC TGTCCTCAAGCAACCCTTCCGTTCCTCCTGTCACTGCTGCCGGCCCCAGACTTCCNAGCT GAAGGCACTGCGGCTGCGATGCTCANGGGGCATGCGACTCACTGCCACCTACCGGTACAT CCTCTCCTGTCACTGCGAGGAATGCATTTCCTGAGCCCGCTGCTGTGTGTGGCTTCTGGA TGGGACAACTGTAGAGGCAGTCCGACCAGCCAGGGAAAGACTGGGCAGAAAGAGTTAGGG CANAAAGGATGCACATTCTNCCGGGACTTGCTC >OriGene 3' read for NM_000266 unedited
TGGACCGCGGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGAATTACTCTTTT TATTTCAAAACGTGGGAATAACTCAAAATTTGAGCCTCCAGGACCAAAACACATTTGAAC CAAACGTTCAGAAGACAAGCCAGGCCACCATTTTGGCAACATGTTTCACATGGACAAGTG GATATTAGAGAATGATGCCCGTGACACGGCTAAAGCTATAGCACACCCACAAATAGATTC ATACTTGGTTGTCTAATTTGCATGCATGAGTATGGTGCATTCTCCATGCCACTAGTACAT ATATGCCTTTTCCAGAGTCAGTGCAGGATCCGTATTTGTGCAAGTCTTTAAAAGTCTGCT CCCTTACAAAATTTTACCATAATTTATCTGAGACAGCCTTCCTGTGACAAATTCTTTATG CTGCTTTTACTTTCAAAAAGTCATTTCTGAATAATAATTATAGCTGTCAAGAGTTCCAGC ATCACATAAAAGAATCTGTTTGTTAGTTATTTTAATGTCAGTTCGCTGGCTGTGAGTAAA CGTAGCTAAACATATCCACATGCTTGGTATCTGGACTTTGAAATCGGTAACCTTTAGCAG CAATGGCAACCTTAGACCAAAATGACAAGGTAAAAAAAAACATCAACAATAACAGAAGAT GTCCCAGGAAAAGCTGGGCTTTTCTACTTTCCAAAGTAAATTCTTCCCCAGCGTGCACCA AACACTGACAGCCTGACACGCTTGTGTATGAGGGCCCACTNTTTCCCACTAATGCTGAAT TGNTGGAAACCCAAACAGCATTGAGAGCCAAGGNGGAAATGCCTNGATCTGAAATGAACC AAAGAAATGTACCANAGAAAGGAGAGGGAACTGCAAAGAAGTTCCAGATATCTCTCTCTG TCACAGCATGTANAGTCTTATTAN |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_000266 |
| Insert Size | 1940 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000266.1, NP_000257.1 |
| RefSeq Size | 1846 bp |
| RefSeq ORF | 402 bp |
| Locus ID | 4693 |
| UniProt ID | Q00604 |
| Domains | CT, Cys_knot |
| Protein Families | Druggable Genome, Secreted Protein |
| Gene Summary | This gene encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway. The protein forms disulfide-linked oligomers in the extracellular matrix. Mutations in this gene result in Norrie disease and X-linked exudative vitreoretinopathy. [provided by RefSeq, Feb 2009] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Hedgehog regulates Norrie disease protein to drive neural progenitor self-renewal
,Brian McNeill, Chantal Mazerolle, Erin A. Bassett, Alan J. Mears, Randy Ringuette, Pamela Lagali, David J. Picketts, Kim Paes, Dennis Rice, and Valerie A. Wallace,
Hum. Mol. Genet., Mar 2013; 22: 1005 - 1016.
[NDP]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206555 | NDP (Myc-DDK-tagged)-Human Norrie disease (pseudoglioma) (NDP) |
CNY 1,800.00 |
|
| RC206555L1 | Lenti ORF clone of Human Norrie disease (pseudoglioma) (NDP), Myc-DDK-tagged |
CNY 4,200.00 |
|
| RC206555L2 | Lenti ORF clone of Human Norrie disease (pseudoglioma) (NDP), mGFP tagged |
CNY 4,200.00 |
|
| RC206555L3 | Lenti ORF clone of Human Norrie disease (pseudoglioma) (NDP), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206555L4 | Lenti ORF clone of Human Norrie disease (pseudoglioma) (NDP), mGFP tagged |
CNY 5,890.00 |
|
| RG206555 | NDP (tGFP-tagged) - Human Norrie disease (pseudoglioma) (NDP) |
CNY 3,400.00 |
|
| SC323838 | NDP (untagged)-Human Norrie disease (pseudoglioma) (NDP) |
CNY 1,800.00 |
