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Metabotropic Glutamate Receptor 7 (GRM7) (NM_000844) Human Untagged Clone
CAT＃: SC119649
GRM7 (untagged)-Human glutamate receptor, metabotropic 7 (GRM7), transcript variant 1
CNY 6,712.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GLUR7; GPRC1G; MGLU7; MGLUR7; NEDSHBA; PPP1R87 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000844 edited
AGCGCGAGCGCGGCGCGCCGGCCGGCTAACCCGAGAAGCGCGAGGCGCCCCAGGCTGGCA GGCGCCGCGGGACCCCTCACCCTCTCTGGTCGCCCCTCCCCGGATTCCCCCACCCTCCGT GCCTGCAGGAAGCCCCTGGGCTTTCCCGGAGGAAGCTCGCCCTGAAGGGCCCGGACCTCG GCGAGCCCACCACCGTTCCCTCAAGCGGCCGCCGCCGCCACCGCAGCAGCCGGGAGCAGC ATGGTCCAGCTGAGGAAGCTGCTCCGCGTCCTGACTTTGATGAAGTTCCCCTGCTGCGTG CTGGAGGTGCTCCTGTGCGCGCTGGCGGCGGCGGCGCGCGGCCAGGAGATGTACGCCCCG CACTCAATCCGGATCGAGGGGGACGTCACCCTCGGGGGGCTGTTCCCCGTGCACGCCAAG GGTCCCAGCGGAGTGCCCTGCGGCGACATCAAGAGGGAAAACGGGATCCACAGGCTGGAA GCGATGCTCTACGCCCTGGACCAGATCAACAGTGATCCCAACCTACTGCCCAACGTGACG CTGGGCGCGCGGATCCTGGACACTTGTTCCAGGGACACTTACGCGCTCGAACAGTCGCTT ACTTTCGTCCAGGCGCTCATCCAGAAGGACACCTCCGACGTGCGCTGCACCAACGGCGAA CCGCCGGTTTTCGTCAAGCCGGAGAAAGTAGTTGGAGTGATTGGGGCTTCGGGGAGTTCG GTCTCCATCATGGTAGCCAACATCCTGAGGCTCTTCCAGATCCCCCAGATTAGTTATGCA TCAACGGCACCCGAGCTAAGTGATGACCGGCGCTATGACTTCTTCTCTCGCGTGGTGCCA CCCGATTCCTTCCAAGCCCAGGCCATGGTAGACATTGTAAAGGCCCTAGGCTGGAATTAT GTGTCTACCCTCGCATCGGAAGGAAGTTATGGAGAGAAAGGTGTGGAGTCCTTCACGCAG ATTTCCAAAGAGGCAGGTGGACTCTGCATTGCCCAGTCCGTGAGAATCCCCCAGGAACGC AAAGACAGGACCATTGACTTTGATAGAATTATCAAACAGCTCCTGGACACCCCCAACTCC AGGGCCGTCGTGATTTTTGCCAACGATGAGGATATAAAGCAGATCCTTGCAGCAGCCAAA AGAGCTGACCAAGTTGGCCATTTTCTTTGGGTGGGATCAGACAGCTGGGGATCCAAAATA AACCCACTGCACCAGCATGAAGATATCGCAGAAGGGGCCATCACCATTCAGCCCAAGCGA GCCACGGTGGAAGGGTTTGATGCCTACTTTACGTCCCGTACACTTGAAAACAACAGAAGA AATGTATGGTTTGCCGAATACTGGGAGGAAAACTTCAACTGCAAGTTGACGATTAGTGGG TCAAAAAAAGAAGACACAGATCGCAAATGCACAGGACAGGAGAGAATTGGAAAAGATTCC AACTATGAGCAGGAGGGTAAAGTCCAGTTCGTGATTGACGCAGTCTATGCTATGGCTCAC GCCCTTCACCACATGAACAAGGATCTCTGTGCTGACTACCGGGGTGTCTGCCCAGAGATG GAGCAAGCTGGAGGCAAGAAGTTGCTGAAGTATATACGCAATGTTAATTTCAATGGTAGT GCTGGCACTCCAGTGATGTTTAACAAGAACGGGGATGCACCTGGGCGTTATGACATCTTT CAGTACCAGACCACAAACACCAGCAACCCGGGTTACCGTCTGATCGGGCAGTGGACAGAC GAACTTCAGCTCAATATAGAAGACATGCAGTGGGGTAAAGGAGTCCGAGAGATACCCGCC TCAGTGTGCACACTACCATGTAAGCCAGGACAGAGAAAGAAGACACAGAAAGGAACTCCT TGCTGTTGGACCTGTGAGCCTTGCGATGGTTACCAGTACCAGTTTGATGAGATGACATGC CAGCATTGCCCCTATGACCAGAGGCCCAATGAAAATCGAACCGGATGCCAGGATATTCCC ATCATCAAACTGGAGTGGCACTCCCCCTGGGCTGTGATTCCTGTCTTCCTGGCAATGTTG GGGATCATTGCCACCATCTTTGTCATGGCCACTTTCATCCGCTACAATGACACGCCCATT GTCCGGGCATCTGGGCGGGAACTCAGCTATGTTCTTTTGACGGGCATCTTTCTTTGCTAC ATCATCACTTTCCTGATGATTGCCAAACCAGATGTGGCAGTGTGTTCTTTCCGGCGAGTT TTCTTGGGCTTGGGTATGTGCATCAGTTATGCAGCCCTCTTGACGAAAACAAATCGGATT TATCGCATATTTGAGCAGGGCAAGAAATCAGTAACAGCTCCCAGACTCATAAGCCCAACA TCACAACTGGCAATCACTTCCAGTTTAATATCAGTTCAGCTTCTAGGGGTGTTCATTTGG TTTGGTGTTGATCCACCCAACATCATCATAGACTATGATGAACACAAGACAATGAACCCT GAGCAAGCCAGAGGGGTTCTCAAGTGTGACATTACAGATCTCCAAATCATTTGCTCCTTG GGATATAGCATTCTTCTCATGGTCACATGTACTGTGTATGCCATCAAGACTCGGGGTGTA CCCGAGAATTTTAACGAAGCCAAGCCCATTGGATTCACTATGTACACGACATGTATAGTA TGGCTTGCCTTCATTCCAATTTTTTTTGGCACCGCTCAATCAGCGGAAAAGTGCCTTGTG TGTTGTGTCTCCTAGCTCTACATACAAACTACCACGCTTACAATCTCCATGAACCTAAGT GCATCAGTGGCGCTGGGGATGCTATACATGCCGAAAGTGTACATCATCATTTTCCACCCT GAACTCAATGTCCAGAAACGGAAGCGAAGCTTCAAGGCGGTAGTCACAGCAGCCACCATG TCATCGAGGCTGTCACACAAACCCAGTGACAGACCCAACGGTGAGGCAAAGACCGAGCTC TGTGAAAACGTAGACCCAAACAGCCCTGCTGCAAAAAAGAAGTATGTCAGTTATAATAAC CTGGTTATCTAACCTGTTCCATTCCATGGAACCATGGAGGAGGAAGACCCTCAGTTATTT TGTCACCCAACCTGGCATAGGACTCTTTGGTCCTACCCGCTTCCCATCACCGGAGGAGCT TCCCCGGCCGGGAGACCAGTGTTAGAGGATCCAAGCGACCTAAACAGCTGCTTTATGAAA TATCCTTACTTTATCTGGGCTTAATAAGTCACTGACATCAGCACTGCCAACTCGGCTGCA ATTGTGGACCTTCCCTACCAAAGGGAGTGTTGAAACTCAAGTCCCGCCCTGGCTCTT >OriGene 5' read for NM_000844 unedited
ATACACTCCTATAGGCGGCCGCGAATTCGGCACGAGGGCGAAGCAGCAAGCCGGTGAGCG CGAGCGCGGCGCGCCGGCCGGCTAACCCGAGAAGCGCGAGGCGCCCCAGGCTGGCAGGCG CCGCGGGACCCCTCACCCTCTCTGGTCGCCCCTCCCCGGATTCCCCCACCCTCCGTGCCT GCAGGAAGCCCCTGGGCTTTCCCGGAGGAAGCTCGCCCTGAAGGGCCCGGACCTCGGCGA GCCCACCACCGTTCCCTCAAGCGGCCGCCGCCGCCACCGCAGCAGCCGGGAGCAGCATGG TCCAGCTGAGGAAGCTGCTCCGCGTCCTGACTTTGATGAAGTTCCCCTGCTGCGTGCTGG AGGTGCTCCTGTGCGCGCTGGCGNGCGGCGGCGCGCGGCCAGGAGATGTACGCCCCGCAC TCAATCCGGATCGAGGGGGGACGTCACCCTCGGGGGGGCTGTTCCCCGTGCACGCCAAGG GTCCCAGCGGAGTGCCCTGCGGCGACATCAAGAGGGAAAACGGGATCCACAGGCTGGAAG CGATGCTCTACGCCCTGGACCAGATCAACAGTGATCCCAACCTACTGCCCAACGTGACGC TGGGCGCGCGGATCCTGGACACTTGTTCCAGGGACACTTACGCGCTCGAACAGTCGCTTA CTTTCGTCCAGGCGCTCATCCAGAAGGACACCTCCGACGTGCGCTGCACCAACGGCGAAA CGGCCGGNTTTTCGTCAAGCCGGAGAAAATAATTTGGATGAATTGGGGCTCNGGGGAAAT TTCGGTCTCCATCATGGTAAGCCAAAATCCTGAGGCTCTTCCAGATCCCCCAGATAATTA TGCATCACCGCACCCGAGCTAATGATGACCGGNGCTATGATTCTTTTTTTGCGTGGGGCA CCCGATTCTTCAAGCCAGCCATGGAGACATTGAAAGGCCCTAGCTGGAATTTTGTCTACC TCCCTGGAAGGAATATGAAAAAAGGGTGGATCCTCACA >OriGene 3' read for NM_000844 unedited
TTCTATGGACCCGCGGCCGCAATCTAAAATCGAGTTTTTTTTTTTTTTTTTTAAAAAGTT AACCAAAGTATTTTATTGATACATTCTTGGACAATATCACAGAATTGAAAGAGAATGGAA AGAGGGAATTTTTCAGCAAGGGTTGTTTTTTTCCACTAAATTGGCACATAAGCAGCAAGA TTAACGAAAGTACTTATTACAAACAGTAAAAAACATACATGCTTTTTTTCCTAAAGTCCT TATCACACTGATCAGTCAAAGGGGGCATGAACAAAACCTCAAGACATGAAAAATCCATAT TCTTTCCTTCAAACAGCTTAATAATTATTAAAATTATTGCAAAATATTCATATACCCTAA TTAAAAATAACAAAAGAGAACACAAATACAAATATTGAACATAATAAACATGTACTGTAA AATACATTACTGGCATGCATTCCAAAGATCAAGACCTCTATTCAGTTCAGCCAATACCTT CCTTTTATGTAACCTATCATATACCAAAGATAGGTGGGGCATACTTTCTCAGCACAGTTT TTGGTCTTTAAACATCTTTTTTGTCTTAAAAAAAAAAACATGATGTGCAGTGGTACTATA ATCGTAATTATACAGTCATGTACAGATGTACTTGTTTTAGTCTGCCAAGATTGCTTTAAA ATTTTAATTGTTTTAAAATTTTTCCAAATATTCCACCGTCTGAGAGAATAGGGCTCTATG AAAACCAGGCATTCGAAAACAAACAGTGAACCGAGGTACGACATCAGATGGCAAAAGTGC AAACGGTCTCTACCAACTGTACAGAACAATTTCAAACCTTGCACCCTAGAAGTCATACGT AATAAGACAGGTCACCCACAACGTCCTGTGGCTCTCAGGGGCCATTCTAAGAGCAGGCGG GAATTTGAGTTCACATTCCTTGTTAGGGAAGGCCAATTGCACCGTTTGCATCCTATCCAG GCTATTACCCAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000844 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000844.2, NP_000835.1 |
| RefSeq Size | 4021 bp |
| RefSeq ORF | 2748 bp |
| Locus ID | 2917 |
| UniProt ID | Q14831 |
| Domains | 7tm_3, ANF_receptor |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009] Transcript Variant: This variant (1, also known as hmGluR7a) encodes the predominant isoform (a). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217402 | GRM7 (Myc-DDK-tagged)-Human glutamate receptor, metabotropic 7 (GRM7), transcript variant 1 |
CNY 6,704.00 |
|
| RC217402L1 | Lenti ORF clone of Human glutamate receptor, metabotropic 7 (GRM7), transcript variant 1, Myc-DDK-tagged |
CNY 9,104.00 |
|
| RC217402L2 | Lenti ORF clone of Human glutamate receptor, metabotropic 7 (GRM7), transcript variant 1, mGFP tagged |
CNY 11,500.00 |
|
| RC217402L3 | Lenti ORF clone of Human glutamate receptor, metabotropic 7 (GRM7), transcript variant 1, Myc-DDK-tagged |
CNY 11,500.00 |
|
| RC217402L4 | Lenti ORF clone of Human glutamate receptor, metabotropic 7 (GRM7), transcript variant 1, mGFP tagged |
CNY 11,500.00 |
|
| RG217402 | GRM7 (tGFP-tagged) - Human glutamate receptor, metabotropic 7 (GRM7), transcript variant 1 |
CNY 8,304.00 |
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