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CD49b (ITGA2) (NM_002203) Human Untagged Clone
CAT＃: SC118747
ITGA2 (untagged)-Human integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2)
CNY 12,344.00
| Cited in 1 publication. |
Product images
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BR; CD49B; GPIa; HPA-5; VLA-2; VLAA2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118747 sequence for NM_002203 edited (data generated by NextGen Sequencing)
ATGGGGCCAGAACGGACAGGGGCCGCGCCGCTGCCGCTGCTGCTGGTGTTAGCGCTCAGT CAAGGCATTTTAAATTGTTGTTTGGCCTACAATGTTGGTCTCCCAGAAGCAAAAATATTT TCCGGTCCTTCAAGTGAACAGTTTGGCTATGCAGTGCAGCAGTTTATAAATCCAAAAGGC AACTGGTTACTGGTTGGTTCACCCTGGAGTGGCTTTCCTGAGAACCGAATGGGAGATGTG TATAAATGTCCTGTTGACCTATCCACTGCCACATGTGAAAAACTAAATTTGCAAACTTCA ACAAGCATTCCAAATGTTACTGAGATGAAAACCAACATGAGCCTCGGCTTGATCCTCACC AGGAACATGGGAACTGGAGGTTTTCTCACATGTGGTCCTCTGTGGGCACAGCAATGTGGG AATCAGTATTACACAACGGGTGTGTGTTCTGACATCAGTCCTGATTTTCAGCTCTCAGCC AGCTTCTCACCTGCAACTCAGCCCTGCCCTTCCCTCATAGATGTTGTGGTTGTGTGTGAT GAATCAAATAGTATTTATCCTTGGGATGCAGTAAAGAATTTTTTGGAAAAATTTGTACAA GGCCTGGATATAGGCCCCACAAAGACACAGGTGGGGTTAATTCAGTATGCCAATAATCCA AGAGTTGTGTTTAACTTGAACACATATAAAACCAAAGAAGAAATGATTGTAGCAACATCC CAGACATCCCAATATGGTGGGGACCTCACAAACACATTTGGAGCAATTCAATATGCAAGA AAATATGCTTATTCAGCAGCTTCTGGTGGGCGACGAAGTGCTACAAAAGTAATGGTAGTT GTAACTGACGGTGAATCACATGATGGTTCAATGTTGAAAGCTGTGATTGATCAATGCAAC CATGACAATATACTGAGGTTTGGCATAGCAGTTCTTGGGTACTTAAACAGAAACGCCCTT GATACTAAAAATTTAATAAAAGAAATAAAAGCAATCGCTAGTATTCCAACAGAAAGATAC TTTTTCAATGTGTCTGATGAAGCAGCTCTACTAGAAAAGGCTGGGACATTAGGAGAACAA ATTTTCAGCATTGAAGGTACTGTTCAAGGAGGAGACAACTTTCAGATGGAAATGTCACAA GTGGGATTCAGTGCAGATTACTCTTCTCAAAATGATATTCTGATGCTGGGTGCAGTGGGA GCTTTTGGCTGGAGTGGGACCATTGTCCAGAAGACATCTCATGGCCATTTGATCTTTCCT AAACAAGCCTTTGACCAAATTCTGCAGGACAGAAATCACAGTTCATATTTAGGTTACTCT GTGGCTGCAATTTCTACTGGAGAAAGCACTCACTTTGTTGCTGGTGCTCCTCGGGCAAAT TATACCGGCCAGATAGTGCTATATAGTGTGAATGAGAATGGCAATATCACGGTTATTCAG GCTCACCGAGGTGACCAGATTGGCTCCTATTTTGGTAGTGTGCTGTGTTCAGTTGATGTG GATAAAGACACCATTACAGACGTGCTCTTGGTAGGTGCACCAATGTACATGAGTGACCTA AAGAAAGAGGAAGGAAGAGTCTACCTGTTTACTATCAAAGAGGGCATTTTGGGTCAGCAC CAATTTCTTGAAGGCCCCGAGGGCATTGAAAACACTCGATTTGGTTCAGCAATTGCAGCT CTTTCAGACATCAACATGGATGGCTTTAATGATGTGATTGTTGGTTCACCACTAGAAAAT CAGAATTCTGGAGCTGTATACATTTACAATGGTCATCAGGGCACTATCCGCACAAAGTAT TCCCAGAAAATCTTGGGATCCGATGGAGCCTTTAGGAGCCATCTCCAGTACTTTGGGAGG TCCTTGGATGGCTATGGAGATTTAAATGGGGATTCCATCACCGATGTGTCTATTGGTGCC TTTGGACAAGTGGTTCAACTCTGGTCACAAAGTATTGCTGATGTAGCTATAGAAGCTTCA TTCACACCAGAAAAAATCACTTTGGTCAACAAGAATGCTCAGATAATTCTCAAACTCTGC TTCAGTGCAAAGTTCAGACCTACTAAGCAAAACAATCAAGTGGCCATTGTATATAACATC ACACTTGATGCAGATGGATTTTCATCCAGAGTAACCTCCAGGGGGTTATTTAAAGAAAAC AATGAAAGGTGCCTGCAGAAGAATATGGTAGTAAATCAAGCACAGAGTTGCCCCGAGCAC ATCATTTATATACAGGAGCCCTCTGATGTTGTCAACTCTTTGGATTTGCGTGTGGACATC AGTCTGGAAAACCCTGGCACTAGCCCTGCCCTTGAAGCCTATTCTGAGACTGCCAAGGTC TTCAGTATTCCTTTCCACAAAGACTGTGGTGAGGACGGACTTTGCATTTCTGATCTAGTC CTAGATGTCCGACAAATACCAGCTGCTCAAGAACAACCCTTTATTGTCAGCAACCAAAAC AAAAGGTTAACATTTTCAGTAACGCTGAAAAATAAAAGGGAAAGTGCATACAACACTGGA ATTGTTGTTGATTTTTCAGAAAACTTGTTTTTTGCATCATTCTCCCTGCCGGTTGATGGG ACAGAAGTAACATGCCAGGTGGCTGCATCTCAGAAGTCTGTTGCCTGCGATGTAGGCTAC CCTGCTTTAAAGAGAGAACAACAGGTGACTTTTACTATTAACTTTGACTTCAATCTTCAA AACCTTCAGAATCAGGCGTCTCTCAGTTTCCAAGCCTTAAGTGAAAGCCAAGAAGAAAAC AAGGCTGATAATTTGGTCAACCTCAAAATTCCTCTCCTGTATGATGCTGAAATTCACTTA ACAAGATCTACCAACATAAATTTTTATGAAATCTCTTCGGATGGGAATGTTCCTTCAATC GTGCACAGTTTTGAAGATGTTGGTCCAAAATTCATCTTCTCCCTGAAGGTAACAACAGGA AGTGTTCCAGTAAGCATGGCAACTGTAATCATCCACATCCCTCAGTATACCAAAGAAAAG AACCCACTGATGTACCTAACTGGGGTGCAAACAGACAAGGCTGGTGACATCAGTTGTAAT GCAGATATCAATCCACTGAAAATAGGACAAACATCTTCTTCTGTATCTTTCAAAAGTGAA AATTTCAGGCACACCAAAGAATTGAACTGCAGAACTGCTTCCTGTAGTAATGTTACCTGC TGGTTGAAAGACGTTCACATGAAAGGAGAATACTTTGTTAATGTGACTACCAGAATTTGG AACGGGACTTTTGCATCATCAACGTTCCAGACAGTACAGCTAACGGCAGCTGCAGAAATC AACACCTATAACCCTGAGATATATGTGATTGAAGATAACACTGTTACGATTCCCCTGATG ATAATGAAACCTGATGAGAAAGCCGAAGTACCAACAGGAGTTATAATAGGAAGTATAATT GCTGGAATCCTTTTGCTGTTAGCTCTGGTTGCAATTTTATGGAAGCTCGGCTTCTTCAAA AGAAAATATGAAAAGATGACCAAAAATCCAGATGAGATTGATGAGACCACAGAGCTCAGT AGCTGA Clone variation with respect to NM_002203.3 759 c=>t;825 g=>a;3252 c=>t >OriGene 5' read for NM_002203 unedited
GAGGCGTCCCTGTTGCCGCTTAGGGCGGTAGGCAAGTACGGTGGNGAGTCTATATAAGCA TAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAA TTCGGCACGAGCTAGAGTGTGCAGGTTCTCGTATCCCTCGGCCAAGGGTATCCTCTGCAA ACCTCTGCAAACCCAGCGCAACTACGGTCCCCCTGNTAGACCCAGGATGGGGCCAGAACG GACAGGGGCCGCGCCGCTGCCGCTGCTGCTGGTGTTAGCGCTCAGTCAAGGCATTTTAAA TTGTTGTTTGGCCTACAATGTTGGTCTCCCAGAAGCAAAAATATTTTCCGGTCCTTCAAG TGAACAGTTTGGCTATGCAGTGCAGCAGTTTATAAATCCAAAAGGCAACTGGTTACTGGT TGGTTCACCCTGGAGTGGCTTTCCTGAGAACCGAATGGGAGATGTGTATAAATGTCCTGT TGACCTATCCACTGCCACATGTGAAAAACTAATTTGCAAACTTCAACAAGCATTCCAAAT GTTACTGAGATGAAAACCAACATGAGCCCTCGCTTGATCCTCACCAGGAACATGGGAACT GGAAGGTTTCTCACTTGTGGGTCCTCTGTGGGCACAGCAATGTGGAAATCAGTTAACCCA ACGGGGGGGTGTTCTGACTCAGTCCCGAATTTAACTTTTAAGCCGGTTTTTACCTGGACT TAGCCCGGGCCCTTCCTAATAAATGTTGGGGTGGGGGGGGAGAAATAAAAAAGTTTTTTC CTGGGTAGCAAGAAAAAATTTTTGGAAAAATTTGTCCAGGCCCGGAATTGGCCCCCCAGA AACCACGGGGGGTTAATTTCAGTTTCCCAAAATCCCAGATTGGGTTTACTTTGACCCTTT TAAACCCAAAAAAATGTTTTGACCCTCCCCAAACTCCAATTGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002203 |
| Insert Size | 5000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002203.2, NP_002194.1 |
| RefSeq Size | 5361 bp |
| RefSeq ORF | 3546 bp |
| Locus ID | 3673 |
| UniProt ID | P17301 |
| Domains | FG-GAP, VWA |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer |
| Gene Summary | This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] Transcript Variant: This variant (1) encodes the functional protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Development of Transgenic Cloned Pig Models of Skin Inflammation by DNA Transposon-Directed Ectopic Expression of Human ?1 and ?2 Integrin
,null,
PLoS ONE
,PubMed ID 22590584
[ITGA2]
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Other Versions
| SKU | Description | Size | Price |
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| RC212617L1 | Lenti ORF clone of Human integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2), Myc-DDK-tagged |
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| RC212617L2 | Lenti ORF clone of Human integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2), mGFP tagged |
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| RC212617L3 | Lenti ORF clone of Human integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2), Myc-DDK-tagged |
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| RC212617L4 | Lenti ORF clone of Human integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2), mGFP tagged |
CNY 14,736.00 |
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| RG212617 | ITGA2 (tGFP-tagged) - Human integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2) |
CNY 13,936.00 |
