TNK1 (NM_003985) Human Untagged Clone
CAT＃: SC117643
TNK1 (untagged)-Human tyrosine kinase, non-receptor, 1 (TNK1)
CNY 4888.00
CNY 7220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | KOS1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003985 edited
AGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAACCGTCAGAATTTT GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTTGACCAGGTGGAGCT GGAGACCTGGTCTCTCTAGGGCCTACCCTGAGCTCACCATCTGAAGGAGAGTGCCATCAT CCTTAGGAACTCCTTCTCCAGACATGCTTCCTGAGGCTGGCTCTCTGTGGCTACTGAAGC TGCTCCGGGACATCCAGTTGGCCCAGTTTTACTGGCCCATCCTTGAGGAGCTTAATGTCA CTCGGCCAGAGCACTTCGACTTTGTAAAGCCTGAGGACCTGGACGGCATTGGCATGGGCC GGCCTGCCCAGCGCAGACTGTCCGAAGCTCTGAAAAGGCTACGTTCTGGGCCTAAGTCTA AGAACTGGGTCTACAAGATCCTTGGAGGTTTTGCCCCTGAGCACAAGGAGCCCACCCTGC CCTCGGACAGCCCACGGCACCTCCCTGAGCCAGAGGGGGGCCTCAAGTGTCTGATCCCAG AGGGTGCTGTTTGCAGAGGGGAGCTGCTGGGTTCAGGCTGCTTCGGTGTGGTGCACCGAG GGCTGTGGACGCTGCCCAGTGGCAAGAGTGTCCCAGTGGCTGTCAAGTCCCTCCGGGTAG GTCCCGAAGGCCCGATGGGCACAGAACTGGGGGACTTCCTGCGAGAGGTATCGGTCATGA TGAACTTGGAGCACCCACACGTGCTGCGTCTGCACGGCCTTGTACTGGGCCAGCCTCTGC AGATGGTGATGGAGCTGGCGCCACTGGGCTCCCTGCACGCGCGCCTAACGGCCCCGGCCC CGACACCCCCGCTGCTCGTGGCCCTGCTCTGCCTCTTCCTGCGGCAGCTGGCGGGAGCCA TGGCGTACCTGGGGGCCCGCGGGCTGGTGCACCGAGACCTCGCTACGCGCAACCTACTGC TGGCGTCGCCGCGCACCATCAAGGTGGCTGACTTCGGGCTGGTGCGGCCTCTGGGCGGTG CCCGGGGCCGCTACGTCATGGGCGGGCCCCGCCCTATCCCCTACGCCTGGTGTGCCCCAG AGAGCCTGCGCCACGGAGCCTTCTCGTCTGCCTCGGACGTGTGGATGTTTGGGGTGACGC TGTGGGAGATGTTCTCCGGGGGCGAGGAACCCTGGGCCGGGGTCCCACCGTACCTCATCC TGCAGCGGCTGGAGGACAGAGCCCGGCTGCCTAGGCCTCCCCTCTGCTCCAGGGCCCTCT ACTCCCTCGCCTTGCGCTGCTGGGCCCCCCACCCTGCCGACCGGCCTAGCTTTTCCCACC TGGAGGGGCTGCTGCAAGAGGCCGGGCCTTCGGAAGCATGTTGTGTGAGGGATGTCACAG AACCAGGCGCCCTGAGGATGGAGACTGGTGACCCCATCACAGTCATCGAGGGCAGCCCCG ACTCCACAATCTGGAAGGGCCAGAATGGTCGCACCTTCAAAGTGGGCAGCTTCCCAGCCT CGGCAGTGACGCTGGCAGATGCGGGGGGCTTGCCAGCCACCCGTCCAGTCCACAGAGGCA CCCCTGCCCGGGGAGATCAACACCCAGGAAGCATAGATGGAGACAGAAAGAAGGCAAATC TTTGGGATGCGCCCCCAGCACGGGGCCAGAGGAGGAACATGCCCCTGGAGAGGATGAAAG GCATTTCCAGGAGTCTGGAGTCAGTTCTGTCCCTCGGTCCTCGTCCCACAGGGGGTGGTT CAAGCCCCCCTGAAATTCGACAAGCCAGAGCTGTGCCCCAGGGACCTCCAGGCCTGCCTC CACGCCCACCTTTATCCTCTAGCTCTCCTCAGCCCAGCCAGCCCTCTAGGGAGAGGCTTC CCTGGCCCAAAAGAAAACCCCCACACAATCACCCCATGGGAATGCCTGGAGCCCGTAAAG CCGCTGCCCTCTCTGGAGGCCTCTTGTCCGATCCTGAGTTGCAGAGGAAGATTATGGAGA TGGAGCTGAGTGTGCATGGGGTCACCCACCAGGAGTGCCAGACAGCACTAGGAGCCACTG GGGGAGATGTGGTTTCTGCCATCCGGAACCTCAAGGTAGATCAGCTCTTCCACCTGAGTA GCCGGTCCAGAGCTGACTGCTGGCGCATCCTGGAGCATTACCAGTGGGACCTCTCAGCTG CCAGCCGCTATGTCCTGGCCAGGCCCTGAGCTCAGCTTCTGCGGGCACAGACACCAGCAT GAAAAGCCTAGGCCCCTGAGGGCCTGGCCACATGGGACCAAGCGGAACCAGAACAAGGTC CCGACAGGGGTAGACGTTCCACCTGGGGAGATCCCACCTGCCGTAGGCACATGGAGGAGG AGCCCAGAGTTGGGCACTGGCAAATGTCTCCTCCCTCCCATGCTCCTTGGCTTCTGAAGG CTGAAGCTCCTTTGGCTGGGCCAAGAAGGATCTAGTCTGCCCACTACATTCTCAAACAAG AGGACTTGGAGGAAAAGAGCTGCTATACATCATATGCAGAGGAAGCTTCTACGCGCTAGA GAGGATCAAGGGGCCACACTGGACCATGTGAACAGCCATCCTGAACTGCCATCAGCTACC ACACTGGACTCTGCAGGGCAGCCATCCTGGATGATGGAAGCCACCATATTGACTTGGGGT ATAGGCCCAAACTGCCTTCGTTTGGTCCAGGGCCATCGTGGGTGATGACGATTGCTCTCT TGCACTCAAGGACATTTGATGCTGGTAGTATGGATTATGAGATGGACTAGCCCCTGCCCC AGCCCAGCTCTCACATTCCCCTTTGTTTTTTCCCATACCAACTGCTTCTACCCTCCCCTA TTACATACATCTTTCAATGTCAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCG CGGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTG >OriGene 5' read for NM_003985 unedited
GTTCANNTATTTGTAATACGACTCACTATTAGGGCGGCCGCGAATTCGCACGAGGCTTGA CCGGTGGAGCTGGAGACCTGGTCTCTCTAGGGCCTACCCTGAGCTCACCATCTGAAGGAG AGTGCCATCATCCTTAGGAACTCCTTCTCCAGACATGCTTCCTGAGGCTGGCTCTCTGTG GCTACTGAAGCTGCTCCGGGACATCCAGTTGGCCCAGTTTTACTGGCCCATCCTTGAGGA GCTTAATGTCACTCGGCCAGAGCACTTCGACTTTGTAAAGCCTGAGGACCTGGACGGCAT TGGCATGGGCCGGCCTGCCCAGCGCAGACTGTCCGAAGCTCTGAAAAGGCTACGTTCTGG GCCTAAGTCTAAGAACTGGGTCTACAAGATCCTTGGAGGTTTTGCCCCTGAGCACAAGGA GCCCACCCTGCCCTCGGACAGCCCACGGCACCTCCCTGAGCCAGAGGGGGGCCTCAAGTG TCTGATCCCAGAGGGTGCTGTTTGCAGAGGGGAGCTGCTGGGTTCAGGCTGCTTCGGTGT GGTGCACCGAGGGCTGTGGACGCTGCCCAGTGGCAAGAGTGTCCCAGTGGCTGTCAAGTC CCTCCGGGTAGGTCCCGAAGGCCCGATGGGCACAGAACTGGGGGACTTCCTGCGAGAGGT ATCGGTCATGATGAACTTGGAGCACCCACACGTGCTGCGTCTGCACGGCCTTGTACTGGG CCAGCCTCTGCAGATGGTGATGGAGCTGGCGCCCACTGGCTCCCTGCACGCGCGCCTAAC GGCCCCGCCCCGAACCCCCGCTGCTCGTGGCCCTGCTCTGCCTCTTCCCTGCGCAGCTGG CGGGAGCCATGGCGTACCCTGGGGCCCGCGGGCTGGTGCACCGAGACTCGCTACGCGCAA CTACTGGTGGCGTCGCCGCGCACCATCAGGTGGCTGACT >OriGene 3' read for NM_003985 unedited
GGGGGGGGGGGGAANNNNNNNNNNTTTNNNNNNNTTNNNTTTCTGTGNNACCGCGGCCCG CATTTTANGATCGAGTTTTTTTTTTTTTTTTTTGACATTGAAAGAGTATGTAATAGGGGA GGGTAGAAGCAGTTGGTATGGGAAAAAACAAAGGGGAATGTGAGAGCTGGGCTGGGGCAG GGGCTAGTCCATCTCATAATCCATACTACCAGCATCAAATGTCCTTGAGTGCAAGAGAGC AATCGTCATCACCCACGATGGCCCTGGACCAAACGAAGGCAGTTTGGGCCTATACCCCAA GTCAATATGGTGGCTTCCATCATCCAGGATGGCTGCCCTGCAGAGTCCAGTGTGGTAGCT GATGGCAGTTCAGGATGGCTGTTCACATGGTCCAGTGTGGCCCCTTGATCCTCTCTAGCG CGTAGAAGCTTCCTCTGCATATGATGTATAGCAGCTCTTTTCCTCCAAGTCCTCTTGTTT GAGAATGTAGTGGGCAGACTAGATCCTTCTTGGCCCAGCCAAAGGAGCTTCAGCCTTCAG AAGCCAAGGAGCATGGGAGGGAGGAGACATTTGCCAGTGCCCAACTCTGGGCTCCTCCTC CATGTGCCTACGGCAGGTGGGATCTCCCCAGGTGGAACGTCTACCCCTGTCGGNACCTTG TTCTGGTTCCGCTTGGTCCCATGTGGGCCAGCCCTCAGGNGCCTANGCTTTTCATGCTGG TGTCTGTGCCCGCAAAAGCTGAGCTCAGGGCCTGGGCCAGACATANCGGCTGGCAGCTGA GAGGTCCACTGGGTATGCTCCAGGATGCGCCAGCAGTCAGCTCTGGACCGCTACTCANGT GGAAGAGCTGATCTACCTTGAGGTNCGGATGGCAGAACCACATCTCCCCAGTGCTCCTAA GCTGNCTGCACTCCTGGTGGNTGACCCATGCCACTCAGNNTCATCTCCTATACTCCTCTG CACTCAGAAGN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003985 |
| Insert Size | 2850 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003985.1, NP_003976.1 |
| RefSeq Size | 2771 bp |
| RefSeq ORF | 2001 bp |
| Locus ID | 8711 |
| UniProt ID | Q13470 |
| Domains | pkinase, TyrKc, SH3, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Gene Summary | The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] Transcript Variant: This variant (2) uses an alternate in-frame acceptor splice site at an internal coding exon compared to variant 1. This results in a shorter isoform (2) missing a 5 aa protein segment compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223073 | TNK1 (Myc-DDK-tagged)-Human tyrosine kinase, non-receptor, 1 (TNK1) |
CNY 4920.00 |
|
| RC223073L1 | Lenti ORF clone of Human tyrosine kinase, non-receptor, 1 (TNK1), Myc-DDK-tagged |
CNY 7320.00 |
|
| RC223073L2 | Lenti ORF clone of Human tyrosine kinase, non-receptor, 1 (TNK1), mGFP tagged |
CNY 5890.00 |
|
| RC223073L3 | Lenti ORF clone of Human tyrosine kinase, non-receptor, 1 (TNK1), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC223073L4 | Lenti ORF clone of Human tyrosine kinase, non-receptor, 1 (TNK1), mGFP tagged |
CNY 7320.00 |
|
| RG223073 | TNK1 (tGFP-tagged) - Human tyrosine kinase, non-receptor, 1 (TNK1) |
CNY 6520.00 |
|
| SC323530 | TNK1 (untagged)-Kinase deficient mutant (K148M) of Human tyrosine kinase, non-receptor, 1 (TNK1) |
CNY 4888.00 |
