CD101 (NM_004258) Human Untagged Clone
CAT＃: SC117463
CD101 (untagged)-Human CD101 molecule (CD101)
CNY 10672.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EWI-101; IGSF2; V7 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117463 sequence for NM_004258 edited (data generated by NextGen Sequencing)
ATGGCAGGCATCTCATATGTGGCATCTTTCTTTCTCCTTCTGACTAAGCTCAGCATTGGC CAGAGAGAAGTAACAGTTCAGAAAGGACCACTGTTTAGAGCTGAAGGTTACCCAGTCAGC ATTGGCTGCAATGTAACTGGCCACCAGGGACCTTCTGAGCAGCATTTCCAGTGGTCTGTT TACCTGCCGACAAACCCGACCCAGGAAGTCCAGATCATTAGCACCAAGGATGCTGCCTTC TCTTACGCAGTATATACGCAGCGGGTGCGAAGCGGAGACGTCTACGTGGAGAGGGTCCAG GGCAACTCAGTCTTGTTGCACATCTCAAAACTCCAGATGAAGGATGCTGGCGAGTATGAG TGTCACACACCAAACACTGATGAGAAATACTATGGAAGTTACAGTGCAAAGACTAATCTA ATTGTTATTCCAGATACCCTCTCTGCCACCATGAGTTCTCAGACTCTCGGTAAGGAGGAA GGTGAGCCATTAGCCCTCACCTGTGAGGCATCCAAAGCCACAGCCCAACATACTCACCTC TCTGTCACCTGGTACCTAACACAGGATGGAGGAGGAAGCCAAGCCACTGAGATTATTTCT CTCTCCAAAGATTTTATATTGGTCCCTGGGCCCTTGTATACAGAGCGGTTTGCAGCCAGT GACGTACAGCTCAACAAACTGGGACCCACTACATTCAGGCTGTCCATAGAGAGGCTCCAG TCCTCAGATCAGGGTCAGCTGTTCTGTGAGGCAACGGAATGGATTCAGGATCCAGATGAA ACTTGGATGTTCATCACCAAAAAGCAGACCGATCAAACCACTCTGAGGATCCAGCCAGCA GTGAAAGATTTTCAAGTCAACATTACAGCTGACAGCTTGTTTGCTGAAGGGAAACCCTTA GAACTGGTTTGCCTGGTTGTAAGCAGTGGCCGTGACCCACAGCTTCAAGGCATTTGGTTC TTCAATGGGACTGAAATTGCTCACATTGATGCTGGTGGAGTCCTGGGCCTGAAGAATGAC TACAAAGAGAGAGCAAGTCAAGGAGAGCTCCAGGTTTCAAAGTTAGGCCCCAAGGCTTTC TCTCTCAAGATCTTCTCTCTGGGCCCAGAGGATGAAGGCGCCTACAGATGTGTGGTAGCA GAGGTCATGAAAACACGCACAGGTTCCTGGCAGGTGCTTCAGAGAAAGCAGTCACCAGAC AGCCACGTGCACCTGAGGAAGCCAGCAGCAAGAAGTGTGGTCGTGTCTACCAAGAACAAG CAGCAAGTTGTGTGGGAAGGAGAGACACTCGCCTTTCTCTGTAAGGCTGGTGGAGCTGAA AGTCCCCTGTCTGTGAGCTGGTGGCACATCCCACGGGACCAGACACAGCCCGAGTTTGTG GCTGGCATGGGGCAGGATGGCATTGTGCAGCTGGGTGCCTCCTATGGGGTACCCAGTTAC CATGGCAACACAAGGCTGGAGAAAATGGACTGGGCCACCTTCCAGCTGGAGATCACCTTC ACTGCCATCACAGACAGTGGCACATATGAGTGCAGAGTATCTGAGAAGTCTCGGAACCAG GCCAGAGATCTGAGCTGGACTCAGAAGATTTCAGTTACTGTAAAGTCTCTGGAGTCAAGT TTACAAGTTAGTCTGATGAGCCGTCAGCCGCAAGTGATGTTAACCAACACCTTTGACCTG TCCTGTGTCGTGAGGGCCGGTTACTCTGACCTCAAGGTGCCACTCACTGTGACGTGGCAG TTCCAGCCAGCTAGCTCTCACATCTTCCACCAGCTTATTCGAATCACCCACAATGGCACT ATTGAATGGGGGAATTTCCTATCCCGGTTCCAAAAGAAGACGAAAGTGTCGCAGTCTTTA TTTCGTTCACAACTCCTAGTCCATGATGCCACTGAGGAAGAGACAGGAGTGTATCAGTGT GAAGTAGAAGTTTATGACAGAAATTCCCTATACAACAACCGCCCCCCGAGGGCTTCTGCC ATCTCTCACCCACTGAGGATAGCCGTCACTTTACCAGAGAGCAAGCTAAAAGTGAATTCA AGGAGTCAAGTCCAAGAGCTCTCCATCAACTCCAACACTGATATAGAATGTAGCATCTTG TCCCGGTCCAATGGAAACCTTCAGTTAGCCATTATTTGGTATTTTTCTCCTGTTTCCACT AATGCCTCTTGGCTAAAGATCCTGGAGATGGACCAAACCAATGTTATAAAAACTGGGGAT GAGTTTCACACCCCACAGAGAAAACAAAAATTTCATACTGAGAAGGTTTCCCAAGACTTA TTTCAGCTGCACATTCTGAATGTGGAAGACAGCGATCGGGGCAAATATCACTGTGCTGTG GAGGAATGGCTCCTGTCTACAAATGGCACTTGGCACAAGCTTGGAGAAAAGAAGTCAGGA CTAACAGAATTGAAACTCAAGCCCACAGGAAGTAAGGTACGTGTCTCCAAAGTGTACTGG ACCGAAAATGTGACTGAGCACAGAGAAGTGGCCATCCGCTGCAGCCTGGAGAGTGTAGGC AGCTCAGCCACTCTGTACTCTGTGATGTGGTACTGGAACAGAGAAAACTCTGGAAGTAAA TTGCTGGTGCACTTGCAACATGATGGCTTGCTGGAGTATGGGGAAGAGGGGCTCAGGAGG CACCTGCACTGTTACCGTTCATCCTCTACAGACTTTGTCCTGAAGCTTCATCAGGTGGAG ATGGAGGATGCAGGAATGTACTGGTGTAGGGTGGCAGAGTGGCAGCTCCATGGACACCCA AGCAAGTGGATTAATCAAGCATCCGATGAGTCACAGCGGATGGTGCTCACGGTGCTGCCT TCAGAGCCCACGCTTCCTTCCAGGATCTGCTCCTCGGCCCCTTTACTCTATTTCCTGTTC ATCTGTCCCTTCGTCCTGCTCCTCCTTCTGCTCATCTCCCTCCTCTGCTTATACTGGAAG GCCAGGAAGTTGTCAACACTGCGTTCCAACACACGGAAAGAAAAAGCTCTCTGGGTGGAC TTGAAAGAGGCTGGAGGTGTGACCACAAATAGGAGGGAAGACGAGGAGGAAGATGAAGGC AACTGA Clone variation with respect to NM_004258.3 1243 a=>g >OriGene 5' read for NM_004258 unedited
GGATTTTGTAATACGACTCACTATAGGGCGGCNCGCGATTCGGCACCAGGNACTGTGCTG GCCCAAATGGCAGGCATCTCATATGTGGCATCTTTCTTTCTCCTTCTGACTAAGCTCAGC ATTGGCCAGAGAGAAGTAACAGTTCAGAAAGGACCACTGTTTAGAGCTGAAGGTTACCCA GTCAGCATTGGCTGCAATGTAACTGGCCACCAGGGACCTTCTGAGCAGCATTTCCAGTGG TCTGTTTACCTGCCGACAAACCCGACCCAGGAAGTCCAGATCATTAGCACCAAGGATGCT GCCTTCTCTTACGCAGTATATACGCAGCGGGTGCGAAGCGGAGACGTCTACGTGGAGAGG GTCCAGGGCAACTCAGTCTTGTTGCACATCTCAAAACTCCAGATGAAGGATGCTGGCGAG TATGAGTGTCACACACCAAACACTGATGAGAAATACTATGGAAGTTACAGTGCAAAGACT AATCTAATTGTTATTCCAGATACCCTCTCTGCCACCATGAGTTCTCAGACTCTCGGTAAG GAGGAAGGTGAGCCATTAGCCCTCACCTGTGAGGCATCCAAAGCCACAGCCCAACATACT CACCTCTCTGTCACCTGGTACCTAACACAGGATGGAGGAGGAAGCCAAGCCACTGAGATT ATTTCTCTCTCCAAAGATTTTATATTGGTCCCTGGGCCCTTGTATACAGAGCGGTTTGCA GCCAGTGACGTACAGCTCAACAAACTGNGACCCACTACATTCAGGCTGTNCATAGAGAGG CTCCAGTCCTCAGATCAGGGTCAGCTGTTCTGTGAGGCAACGGAATGGATTCANGATCCA GATTGAACTTGGATGNTCATCACCAAAAAGCAGACCGATCAAACCACTCTGAGGATCCAG CCAGCAGTGAAAGATTTCAAGTCACATTCAGCTGACAGCTTGTTGCTGAAGGAAACCNTT ANACTGNTTGCCTGNTGTAANCAATGCCGTGACACAA >OriGene 3' read for NM_004258 unedited
GCGGCGGGCCANCANCNTCCCTCTTNNNNNNNNNNNNTTACTGTGANCCGCGGNCCGCAT TCTGANGATCGGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTGGGGGGGGGGAGAAAAGGGAGTTTTTTTTTTTTTTTACTTGGCACAAACAAGGGAAGC CCTGGGAATACCCTCCAAAGCGGGGTCTTTTAAGGAAAGGGACCGGAGGGTTTTATGGGG GGATGGAAAGGGGAAAAAGTGCCTTGGTGCCTGTAGGGGAGGGGGCCCAGGGGCCCCCCC CCAATGAGTCCTCCTGCCCACCCACAGGGCACATGTTACGGGCATGAAACTATAACTCCC CCTGGGGGAGGGACTTCAGGAGGGGAATGAGGAAAGTTCCCTTGGGTTCATCTAAAAATT GCCGGGGTCTGTCAGGAGCTGGTTCCCGGGGACTAGGGCACCCCATTCCACACGGGGCTT GGGAAAAAACAGGCCGCAAGGGCGGAAGCTTTCCTTCCTGGCTGCAGGGGCCTCTTGGGA TTCAAATGCCTTAATTTTCCTCCCCGGGTTCCCTCCTATTTGGGGGCACACCCCCAGCCT TTTTCAAGGCCACCCCGAGAGCTTTTTCTTTCCGGGGGGTGGAACCCACTGTTGAAAACT TCCTGGCCTTCCCGTTTAACCCCCGGGAGGGGAATTACCCTAAGGAGGGGCCGGACCCAA GGGCCCAATGACCCGGAAATTTTATTAAGGGGGCCCAGGACCCAAACCCTGGAAGAAAAC GGGGCTTTTAAGGCACACCGCGGACCCCCATCGCTGTGGGATATTGGAAGGCTTGGAAAA ACCCCTGCCTGGGGGGCCACTGGAGTTGCCCCTTTTCCCCCCTAAACCAAAAATTTTCTG GCTCCCCTTTTTCCCCCTGAGGAAACTTCCGGACAAAATTTTTAGAAGAATAAACGGAAC ACAGCCGGGGGCCTTCTGAACCCCTTTTCCCN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004258 |
| Insert Size | 3750 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004258.1, NP_004249.1 |
| RefSeq Size | 3340 bp |
| RefSeq ORF | 3066 bp |
| Locus ID | 9398 |
| UniProt ID | Q93033 |
| Domains | ig, IGv, IG |
| Protein Families | Transmembrane |
| Gene Summary | Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1, 2 and 3 all encode isoform 1. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219415 | CD101 (Myc-DDK-tagged)-Human CD101 molecule (CD101) |
CNY 10664.00 |
|
| RC219415L1 | Lenti-ORF clone of CD101 (Myc-DDK-tagged)-Human CD101 molecule (CD101) |
CNY 7600.00 |
|
| RC219415L2 | Lenti-ORF clone of CD101 (mGFP-tagged)-Human CD101 molecule (CD101) |
CNY 7600.00 |
|
| RC219415L3 | Lenti-ORF clone of CD101 (Myc-DDK-tagged)-Human CD101 molecule (CD101) |
CNY 7600.00 |
|
| RC219415L4 | Lenti-ORF clone of CD101 (mGFP-tagged)-Human CD101 molecule (CD101) |
CNY 7600.00 |
|
| RG219415 | CD101 (tGFP-tagged) - Human CD101 molecule (CD101) |
CNY 12264.00 |
