DENND2B (NM_005418) Human Untagged Clone
CAT＃: SC116754
ST5 (untagged)-Human suppression of tumorigenicity 5 (ST5), transcript variant 1
CNY 7928.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HTS1; p126; ST5 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_005418 edited
AGCGGGGGGGTCGGGGGTCGGGGGCTGGGGGCTGAGGACTGAGTCGAGCCAGCAGCCCAG GGCATCTGTCCACGCTGTCAGAGGAGCCTCTGGGCGTGGGGCTGGCCCTTAGAGGGCTAC TGCGCTGCTTAACTTGCCTTTCACAGAAAACCACTGGAGGAGATACTCACAAAAATGAAG GGGAAGAACAGGAAACAGGAAGACATGAGATGAAGGAAACAGGAGATTCAACATGGATTT CACACCCTTTGGAGAGTTTCTTTCTTGGATAATTCAGGAAGATGAGAGACTGCTTAGGCG CCACCACTAGTACCATGAGTCCCTGCACTGGTTAAAGCCATCGCCACAACCTGGACAGGC AGCAAGGGCTCTGGGTTTGCAGAGAGCCGAAATGACCATGACTGCCAACAAGAATTCCAG CATCACCCACGGAGCTGGTGGCACTAAAGCCCCTCGGGGGACTCTGAGCAGGTCTCAGTC AGTCTCTCCACCTCCAGTTCTCTCCCCACCAAGGAGTCCCATCTACCCGCTCAGTGATAG TGAAACCTCAGCCTGCAGGTACCCCAGCCACTCCAGCTCCCGGGTGCTCCTCAAGGACCG GCACCCCCCAGCTCCTTCACCCCAGAATCCTCAAGATCCCTCCCCAGATACTTCCCCACC CACCTGTCCCTTCAAGACCGCCAGCTTCGGTTATTTGGACAGAAGCCCTTCGGCGTGCAA GAGAGACGCCCAAAAGGAAAGTGTCCAAGGCGCAGCCCAGGATGTAGCAGGGGTCGCTGC CTGCCTCCCCCTTGCCCAGAGCACGCCATTCCCGGGGCCAGCAGCTGGCCCCCGGGGCGT CTTGCTGACCCGTACCGGTACCCGCGCCCACAGCCTGGGCATCCGGGAGAAGATATCAGC ATGGGAAGGTCGCCGAGAGGCGTCGCCCAGGATGAGCATGTGTGGAGAGAAGCGGGAGGG CTCTGGGAGCGAGTGGGCGGCCAGTGAGGGCTGCCCCAGCCTGGGCTGTCCCAGCGTGGT GCCGTCCCCCTGCAGCTCTGAAAAGACCTTTGATTTCAAGGGCCTCCGGAGGATGAGCAG GACCTTCTCCGAGTGTTCCTACCCAGAGACTGAGGAGGAGGGAGAGGCGCTCCCTGTCCG GGACTCTTTCTACCGGCTGGAGAAACGGCTGGGCCGGAGTGAGCCCAGCGCCTTCCTCAG GGGGCATGGCAGCAGGAAGGAGAGCTCAGCAGTGCTGAGCCGGATCCAGAAAATTGAACA GGTCCTGAAGGAGCAGCCGGGCCGGGGGCTCCCCCAGCTCCCCAGCAGCTGCTACAGCGT GGACCGGGGGAAAAGGAACACTGGAACCTTGGGCTCCTTGGAGGAGCCGGCAGGGGGCGC GAGTGTGAGCGCTGGCAGCCGGGCAGTCGGAGTGGCTGGTGTTGCGGGGGAGGCGGGCCC ACCCCCAGAGAGGGAAGGCAGTGGTTCCACTAAGCCCGGGACCCCTGGAAATAGCCCTAG CTCCCAGCGGCTGCCATCGAAGAGTTCCCTCGATCCCGCTGTGAACCCTGTCCCCAAACC CAAGCGCACCTTTGAATACGAGGCTGACAAGAACCCCAAGAGTAAGCCCAGTAATGGTCT ACCTCCTTCACCCACACCTGCTGCTCCACCTCCCTTGCCCTCCACCCCAGCCCCGCCAGT CACCCGGAGACCCAAGAAGGACATGCGTGGTCACCGCAAGTCCCAGAGCAGAAAATCCTT TGAGTTTGAGGATGCATCCAGTCTCCAGTCCCTGTACCCCTCTTCTCCCACTGAGAATGG TACTGAGAACCAACCCAAGTTTGGATCCAAAAGCACTTTAGAAGAAAATGCCTATGAAGA TATTGTGGGAGATCTGCCCAAGGAGAATCCATATGAGGATGTGGACTTAAAGAGCCGAAG AGCAGGACGAAAATCCCAGCAACTGTCTGAGAACTCCTTGGACTCTTTGCACAGGATGTG GAGTCCTCAGGACAGGAAGTACAACAGCCCGCCCACACAGCTTTCCCTGAAACCCAACAG CCAGTCCCTGCGCAGTGGGAACTGGTCAGAAAGGAAGAGCCACCGGCTGCCACGATTACC CAAGAGGCACAGCCATGACGACATGCTGCTGCTGGCTCAGCTGAGTCTGCCGTCCTCACC CTCCAGCCTCAATGAAGACAGCCTCAGCACCACCAGCGAGCTGCTGTCCAGCCGCCGGGC CCGCCGCATTCCCAAGCTTGTCCAAAGAACTAACTCCATCTACAATGCCAAGAGAGGAAA GAAGAGATTAAAAAAGTTGTCTATGTCCAGCATTGAAACAGCATCACTGAGAGATGAAAA CAGTGAGAGCGAGAGCGACTCTGATGACAGGTTCAAAGCCCACACACAGCGCCTGGTCCA CATCCAGTCGATGCTGAAGCGCGCCCCCAGCTATCGCACGCTGGAGCTGGAGCTGCTGGA GTGGCAGGAGCGGGAGCTTTTTGAGTACTTTGTGGTGGTGTCCCTCAAGAAGAAGCCATC GCGAAACACCTACCTCCCCGAAGTCTCCTACCAGTTTCCCAAGCTGGACCGACCCACCAA GCAGATGCGAGAGGCAGAGGAAAGGCTCAAAGCCATTCCCCAGTTTTGCTTCCCTGATGC CAAGGACTGGCTTCCTGTGTCAGAGTATAGCAGTGAGACCTTTTCTTTCATGCTGACTGG GGAAGATGGCGGCAGACGCTTTGGCTACTGCAGGCGCTTACTGCCAAGTGGGAAAGGGCC CCGGTTGCCAGAGGTGTACTGTGTCATCAGCCGCCTTGGCTGCTTCGGCTTGTTTTCCAA GGTCCTAGATGAGGTGGAGCGCCGGCGTGGGATCTCCGCTGCATTGGTCTATCCTTTCAT GAGAAGTCTCATGGAGTCGCCCTTCCCAGCCCCAGGGAAGACCATCAAAGTGAAGACATT CCTGCCAGGTGCTGGCAATGAGGTGTTAGAGCTGCGGCGGCCCATGGACTCAAGGCTGGA GCACGTGGACTTTGAGTGCCTTTTTACCTGCCTCAGTGTGCGCCAGCTCATCCGAATCTT TGCCTCACTGCTGCTGGAGCGCCGGGTCATTTTTGTGGCAGATAAGCTCAGTACCCTCTC CAGCTGCTCCCACGCGGTGGTGGCCTTGCTCTACCCCTTCTCCTGGCAGCACACCTTCAT TCCTGTCCTCCCGGCCTCCATGATTGACATCGTCTGCTGTCCCACCCCCTTCCTGGTTGG CCTGCTCTCCAGCTCCCTCCCCAAACTGAAGGAGCTGCCTGTGGAGGAGGCGCTGATGGT GAATCTGGGATCTGACCGATTCATCCGACAGATGGACGACGAAGACACGTTGTTACCTAG GAAGTTACAGGCAGCTCTGGAGCAGGCTCTGGAGAGGAAGAATGAGCTGATCTCCCAGGA CTCTGACAGCGACTCCGACGATGAATGTAATACCCTCAATGGGCTGGTGTCGGAGGTGTT TATCCGGTTCTTTGTGGAGACCGTTGGGCACTACTCCCTCTTTCTGACACAGAGTGAGAA GGGAGAGAGGGCCTTTCAGCGAGAGGCCTTCCGCAAATCTGTGGCCTCCAAAAGCATCCG CCGCTTTCTTGAGGTTTTTATGGAGTCTCAGATGTTTGCTGGCTTCATCCAAGACAGGGA GCTAAGAAAGTGTCGGGCAAAGGGCCTTTTTGAGCAGCGAGTGGAGCAGTACTTAGAAGA ACTCCCAGACACTGAGCAGAGTGGAATGAATAAGTTTCTCCGAGGTTTGGGCAACAAAAT GAAGTTTCTCCACAAGAAGAATTAAGCCTCCTTCTCAGTAGCAGAGTCCAGTGCCTTGCA GAGCCTGAAGCCTGGGGAGAAGGCCCAGCCTGGGACCCTCTGGGCTGCTGTGGCTCCTCT GCCCCCACAGATCCTATCCTCCAAGCCAGCCCACCTCTGCCTTCATCATATCCCAGGATA CTGTTTGTAAATAATCTGCTGTAAGCTTTCTTAACTGTTTTTTGTAACAAGCAAAGAGAA TATGGCAAATATTTGTATATTCCCAAGGGGCCGGGTGCTTTCCTGTCCTGCCAGAGCATG GATGAAGTTTCGCTGGGTGCTCGTGACTGGCCAGTTTTGTGCAGCTGACTGTCTCAGCCA AACCACTGATCTTCCCTGGAGGCCTTCGGCCTGCCTGCCTGCCTGCCTGAGGTCCCCGCT GCCAGTCCCGGGCCCTGGAGAGCAGATGCTGTCTTGTTATGTACAGGAGGACCTTTTAAA AAAATCAAGTTTCTATTTTTTGCTGGTAGTCCGCATACCCATACCCTCTGTTTTTGAAAG GCAAAGGCCAATCAGTCCCCATTTGTAGCATGGCACCAGGGTCTTAGGCCTAGTCCTCTC ATTCCTCCCACCCTCCGAGATGGTCAGTGTGTCATGGGAAGCCCACCCCCAGCTCTGCCA GTGCTCTCTGGGCCTGGCTCCCAGTCAGTGGTGGCCACGATGCGGTACAGGGCATCCCTC CTTCCCATCTACGGGTGTTCTCAATAAACAATGTACAGTTGTTTGGGCAAAAAAAAAAAA AAA |
| Restriction Sites | Please inquire |
| ACCN | NM_005418 |
| Insert Size | 4600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to contain 2 SNPs compared with NM_005418.3. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005418.3, NP_005409.3 |
| RefSeq Size | 4571 bp |
| RefSeq ORF | 3414 bp |
| Locus ID | 6764 |
| UniProt ID | P78524 |
| Domains | DENN, dDENN, uDENN |
| Gene Summary | This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1), also known as p126, represents the longest transcript and encodes the longer isoform (1). |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218527 | ST5 (Myc-DDK-tagged)-Human suppression of tumorigenicity 5 (ST5), transcript variant 1 |
CNY 7920.00 |
|
| RC218527L3 | Lenti ORF clone of Human suppression of tumorigenicity 5 (ST5), transcript variant 1, Myc-DDK-tagged |
CNY 5890.00 |
|
| RC218527L4 | Lenti ORF clone of Human suppression of tumorigenicity 5 (ST5), transcript variant 1, mGFP tagged |
CNY 5890.00 |
|
| RG218527 | ST5 (tGFP-tagged) - Human suppression of tumorigenicity 5 (ST5), transcript variant 1 |
CNY 4370.00 |
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