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RASGAP (RASA2) (NM_006506) Human Untagged Clone
CAT＃: SC116045
RASA2 (untagged)-Human RAS p21 protein activator 2 (RASA2)
CNY 6,224.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GAP1M |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_006506 edited
ATGGCGGCGGCGGCGCCTGCTGCTGCGGCGGCTTCTTCCGAGGCGCCAGCGGCGAGTGCG ACTGCAGAGCCCGAGGCCGGGGACCAGGACAGTCGCGAGGTTCGAGTGTTGCAGAGCCTG CGGGGCAAGATCTGTGAAGCAAAAAATTTATTGCCATATCTTGGACCCCACAAAATGAGA GATTGTTTCTGTACCATAAATTTGGACCAGGAAGAAGTTTATCGTACCCAAGTTGTGGAA AAATCTTTAAGCCCATTTTTCAGTGAAGAATTTTACTTTGAGATTCCAAGAACTTTCCAG TATTTGTCTTTCTATGTTTATGATAAGAATGTTTTACAAAGAGATCTCCGTATAGGAAAA GTAGCCATCAAAAAAGAAGACTTGTGTAATCACAGTGGCAAAGAAACTTGGTTTTCATTA CAGCCTGTTGACTCCAATTCAGAGGTTCAGGGTAAAGTTCACCTTGAATTAAAACTGAAT GAACTGATAACGGAGAATGGAACTGTATGCCAGCAGCTTGTTGTACACATCAAGGCATGC CATGGGTTGCCTCTCATAAATGGCCAAAGCTGTGACCCTTATGCAACAGTTTCTCTAGTG GGCCCTTCTAGGAATGACCAAAAGAAGACAAAAGTAAAGAAGAAAACAAGCAATCCGCAG TTTAATGAAATCTTTTATTTTGAGGTAACCAGATCCAGTAGTTACACCAGAAAGTCCCAG TTCCAGGTAGAAGAGGAGGACATTGAAAAGCTAGAAATCAGGATCGACTTGTGGAACAAT GGAAACCTAGTCCAAGATGTTTTCCTAGGTGAGATTAAGGTTCCTGTGAACGTATTAAGA ACTGATTCCTCTCATCAAGCCTGGTACTTGCTACAGCCAAGAGACAATGGAAACAAGTCA TCCAAAACTGATGACCTGGGGTCTCTTCGATTAAATATATGTTATACAGAAGACTACGTG CTTCCTTCAGAGTACTATGGTCCTTTGAAAACTTTGCTGCTAAAATCACCAGATGTTCAA CCAATATCTGCCTCAGCTGCTTACATTTTGAGTGAAATATGTCGAGATAAAAATGATGCT GTTTTGCCCCTTGTACGACTGCTGCTGCACCATGATAAACTTGTTCCTTTTGCCACTGCT GTGGCTGAATTAGACTTGAAGGATACACAAGATGCAAACACAATTTTTAGAGGAAATTCC CTGGCTACCCGATGTCTGGATGAGATGATGAAAATAGTGGGAGGGCACTACCTGAAAGTA ACATTAAAACCTATTCTTGATGAGATATGTGACTCCTCAAAATCCTGTGAAATCGATCCT ATTAAATTGAAAGAGGGAGATAATGTAGAAAATAATAAGGAGAATCTGCGCTACTATGTA GACAAGTTATTCAATACAATTGTAAAATCAAGTATGAGCTGCCCCACTGTAATGTGTGAT ATCTTTTATTCTCTAAGGCAGATGGCTACTCAGAGATTTCCTAATGACCCTCATGTTCAG TATTCTGCAGTGAGCAGCTTTGTATTTCTTCGTTTCTTTGCTGTAGCCGTAGTATCACCT CATACTTTTCATTTGCGACCTCATCATCCAGATGCACAGACAATTAGAACATTAACTCTC ATCTCAAAAACTATACAAACTTTGGGAAGCTGGGGGAGTCTGTCCAAAAGCAAGTCAAGT TTCAAAGAGACATTCATGTGTGAATTTTTCAAAATGTTTCAAGAAGAAGGATATATTATA GCAGTTAAAAAGTTCTTGGATGAAATTTCATCTACTGAAACTAAAGAGTCCAGTGGTACG AGTGAGCCTGTGCACCTGAAAGAAGGTGAGATGTATAAAAGAGCTCAAGGAAGAACTCGG ATTGGAAAAAAGAATTTTAAGAAACGATGGTTCTGCTTAACAAGCAGAGAGCTCACCTAC CACAAACAGCCAGGCAAAGATGCAATCTACACAATCCCAGTAAAAAACATTCTTGCTGTG GAAAAACTGGAAGAGAGCTCTTTCAACAAGAAAAATATGTTCCAAGTAATACATACGGAG AAACCACTCTATGTCCAGGCAAATAACTGTGTAGAAGCTAATGAATGGATAGACGTACTC TGCAGGGTGAGCCGATGCAATCAAAACAGGCTCAGTTTTTATCATCCCTCTGTGTATCTG AACGGAAATTGGCTCTGCTGTCAGGAGACTGGTGAAAACACTCTCGGCTGCAAGCCATGT ACTGCAGGTGTCCCTGCAGACATCCAAATAGATATTGATGAAGACAGAGAAACAGAAAGA ATTTATTCCCTTTTTACCCTCAGTTTACTTAAGCTGCAGAAGATGGAAGAGGCTTGTGGA ACTATTGCAGTCTATCAAGGACCACAGAAAGAGCCTGATGATTATTCTAACTTTGTAATC GAGGATTCTGTAACAACCTTTAAGACAATTCAGCAAATAAAAAGCATAATTGAGAAGCTG GATGAACCTCATGAAAAATATAGGAAGAAAAGATCCAGTAGTGCAAAATATGGGAGCAAG GAAAATCCAATTGTTGGGAAAGCATCTTAG >OriGene 5' read for NM_006506 unedited
AATTGTTCGAATTTTGGTATACGACTTCACTATAGGGCGGCCGCGATTCGGCACCAGGGC AGGGCTGCGGCACGGGCCGGGCGGCACCATGGCGGCGGCGGCGCCTGCTGCTGCGGCGGC TTCTTCCGAGGCGCCAGCGGCGAGTGCGACTGCAGAGCCCGAGGCCGGGGACCAGGACAG TCGCGAGGTTCGAGTGTTGCAGAGCCTGCGGGGCAAGATCTGTGAAGCAAAAAATTTATT GCCATATCTTGGACCCCACAAAATGAGAGATTGTTTCTGTACCATAAATTTGGACCAGGA AGAAGTTTATCGTACCCAAGTTGTGGAAAAATCTTTAAGCCCATTTTTCAGTGAAGAATT TTACTTTGAGATTCCAAGAACTTTCCAGTATTTGTCTTTCTATGTTTATGATAAGAATGT TTTACAAAGAGATCTCCGTATAGGAAAAGTAGCCATCAAAAAAGAAGACTTGTGTAATCA CAGTGGCAAAGAAACTTGGTTTTCATTACAGCCTGTTGACTCCAATTCAGAGGTTCAGGG TAAAGTTCACCTTGAATTAAAACTGAATGAACTGATAACGGAGAATGGAACTGTATGCCA GCAGCTTGTTGTACACATCAAGGCATGCCATGGGTTGCCTCTCATAAATGGCCAAAGCTG TGACCCTTATGCAACAGTTTCTCTAGTGGGCCCTTCTAGGAATGACCAAAAGAAGACCAN AGTAAAGAAGAAAACAAGCCATCCGCAGTTTAATGAAATCTTTTATTTTGAGGGTACCAG ATCCAGTAGTTACACCAGAAAGTCCCAGTTCCAGGTAGAAAGAGGAGGACATTTGAAAGC TANGAATCAGGATCGACTTGTGGGGACATGGAACCCTAGTTCCAGATGTTTTCCTAGGGT GAGATTAGGGTCCTGTGAACGTATTAGAACT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006506 |
| Insert Size | 3070 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_006506.2, NP_006497.2 |
| RefSeq Size | 2592 bp |
| RefSeq ORF | 2550 bp |
| Locus ID | 5922 |
| UniProt ID | Q15283 |
| Domains | C2, BTK, PH, RasGAP |
| Protein Pathways | MAPK signaling pathway |
| Gene Summary | The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] Transcript Variant: This variant (3) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (3) is shorter compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224076 | RASA2 (Myc-DDK-tagged)-Human RAS p21 protein activator 2 (RASA2) |
CNY 6,216.00 |
|
| RC224076L3 | Lenti-ORF clone of RASA2 (Myc-DDK-tagged)-Human RAS p21 protein activator 2 (RASA2) |
CNY 8,616.00 |
|
| RC224076L4 | Lenti-ORF clone of RASA2 (mGFP-tagged)-Human RAS p21 protein activator 2 (RASA2) |
CNY 9,030.00 |
|
| RG224076 | RASA2 (tGFP-tagged) - Human RAS p21 protein activator 2 (RASA2) |
CNY 7,890.00 |
