CysLT1 (CYSLTR1) (NM_006639) Human Untagged Clone
CAT＃: SC115965
CYSLTR1 (untagged)-Human cysteinyl leukotriene receptor 1 (CYSLTR1)
CNY 5488.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CYSLT1; CYSLT1R; CYSLTR; HMTMF81 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115965 sequence for NM_006639 edited (data generated by NextGen Sequencing)
ATGGATGAAACAGGAAATCTGACAGTATCTTCTGCCACATGCCATGACACTATTGATGAC TTCCGCAATCAAGTGTATTCCACCTTGTACTCTATGATCTCTGTTGTAGGCTTCTTTGGC AATGGCTTTGTGCTCTATGTCCTCATAAAAACCTATCACAAGAAGTCAGCCTTCCAAGTA TACATGATTAATTTAGCAGTAGCAGATCTACTTTGTGTGTGCACACTGCCTCTCCGTGTG GTCTATTATGTTCACAAAGGCATTTGGCTCTTTGGTGACTTCTTGTGCCGCCTCAGCACC TATGCTTTGTATGTCAACCTCTATTGTAGCATCTTCTTTATGACAGCCATGAGCTTTTTC CGGTGCATTGCAATTGTTTTTCCAGTCCAGAACATTAATTTGGTTACACAGAAAAAAGCC AGGTTTGTGTGTGTAGGTATTTGGATTTTTGTGATTTTGACCAGTTCTCCATTTCTAATG GCCAAACCACAAAAAGATGAGAAAAATAATACCAAGTGCTTTGAGCCCCCACAAGACAAT CAAACTAAAAATCATGTTTTGGTCTTGCATTATGTGTCATTGTTTGTTGGCTTTATCATC CCTTTTGTTATTATAATTGTCTGTTACACAATGATCATTTTGACCTTACTAAAAAAATCA ATGAAAAAAAATCTGTCAAGTCATAAAAAGGCTATAGGAATGATCATGGTCGTGACCGCT GCCTTTTTAGTCAGTTTCATGCCATATCATATTCAACGTACCATTCACCTTCATTTTTTA CACAATGAAACTAAACCCTGTGATTCTGTCCTTAGAATGCAGAAGTCCGTGGTCATAACC TTGTCTCTGGCTGCATCCAATTGTTGCTTTGACCCTCTCCTATATTTCTTTTCTGGGGGT AACTTTAGGAAAAGGCTGTCTACATTTAGAAAGCATTCTTTGTCCAGCGTGACTTATGTA CCCAGAAAGAAGGCCTCTTTGCCAGAAAAAGGAGAAGAAATATGTAAAGTATAG Clone variation with respect to NM_006639.2 927 c=>t >OriGene 5' read for NM_006639 unedited
NGGTTGAGGATTTTGTNATACGATTTACTATAGGGTCGGCCGCGAAATTCGCACGAGGTG CTTTTACGACCCTACAGGGTATCAAGATACTGTGCAGCTCGCCAACAAGGATTAATTGCA AGGACTGGTAGATCGAATTTACTGAAGACTTGGAGCTTGCTTCTGAGAACAAACGCAAAA GGACAGTAAACTGTGGACCTTGAAGTTAGCAGCGTGGGCTTCCTCTAATATTACACCGTA AAAGGCATTGATCACCATAAGAAGGAACATTTGTGAAGGTACTCCAGTGCCAGAAAGAGG CACAAAGCAGACATATGTAGAGAAACATGGATGAAACAGGAAATCTGACAGTATCTTCTA TCACATGCCATGACACTATTGATGACTTCCGCAATCAAGTGTATTCCACCTTGTACTCTA TGATCTCTGTTGTAGGCTTCTTTGGCAATGGCTTTGTGCTCTATGTCCTCATAAAAACCT ATCACAAGATAGTCAGCCTTCCAAGTATACATGATTAATTTAGCAGTAGCAGATCTACTT TGTGTGTGCACACTGCCTCTCCGTGTGGTCTATTATGTTCACAAAGGCATTTGGCTCTTT GGTGACTTCTTGTGCCGCCTCAGCACCTATGCTTTGTATGTCAACCTCTATTGTAGCATC TTCTTTATGACAGCCATGAGCTCTTTCCGGTGCATTGCAATTGTTTTTCCAGTCCAGAAC ATTAATTTGGTTACACAGAAAAAAAGCCAGGTTTGTGTGTGTAGGTATTTTGCATTTTTG TGATTTTGACCAGTTCTTCATTTCTAATGGCCACACCACCAAAAGATGATGAAAATAATA CCAAGTGCCTTTGAGCTCCCACAAGACATCAAACCTAAAAATCATGTTCTGGTCTCGCCA TATGTGGCATTGTTTGGTTGCCTT >OriGene 3' read for NM_006639 unedited
AAATAATAAANNNNNNNTTATTANNNNNGGCCACTTTTGATTACATTTTTTTTTTTGNAG TAAGTTACTTTTTAAAAACAACTTAAAGGCACACTACACTTCAGCAAAAGCTTGTCCACG CATATTATATTTCAGCCGTAGATGAGTTGTTGTGGCTGTTTTAAGATCAAAGCGTCCACT GTAATATAAAAGTCACTGTAAACATATCCATGATATTCCTGTCAACATACCAATAAAAAG TAATAAAGCAATAATAAAACTTATCGTGAACTTTCACCCATAATGCATATCATACAGCAA AATCTCTTACATATAGTTGTATACATATACATAAATGTATGCACTTCTTAAAAGAATTTG TAACGTGAACATTCACAATTTTCTTCATAAATCCTTTGTAGTTTATTTTGATCCCAGCAA TTGGCATATAGAAAAGTAGATTCCTTTTCCTTTTCTCTTCTTCAGATAAGTTTTTAATTA CTTCTATTTATATATAGGAGTGCCAGTTGTCTGGCTTCTTAAGGAAGAATTGTATGTCAT GGATGGAGAGAAATCTCTACAGGAACCTCACTGAGCAGCTAAAACTCCACTATTCAATTT TGGGAGCCTGAGGCAAAGGCAGAAGAAAACTGGAGACAAACTGGCTTTTGACCAGATTTC TCCTGTTGCCATATTGAACATTGTATGGTGCTTTTAAGACCCTTTAGCTGAATACTAGTC TGTTCTAGCACTTTTACATTCTCTTTTGGAAAGAATGGCCCTTATTTGCCTAGCGAATCA GTACTACAAAAGAAGGTGACAGTACGTTTTATGTAACTCCTGAGTATCTTCAGTTCTCAT CTGATGGCATGCATGCAAAGGAATATGTAGAATGATTCAGAACTATTTGGCCATTTATAT CTAGTTTTATTTTTAATACTTTAACCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006639 |
| Insert Size | 2550 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006639.2, NP_006630.1 |
| RefSeq Size | 1537 bp |
| RefSeq ORF | 1014 bp |
| Locus ID | 10800 |
| UniProt ID | Q9Y271 |
| Domains | 7tm_1 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
| Gene Summary | This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2, 3, and 4 encode the same protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207763 | CYSLTR1 (Myc-DDK-tagged)-Human cysteinyl leukotriene receptor 1 (CYSLTR1) |
CNY 5488.00 |
|
| RC207763L1 | Lenti ORF clone of Human cysteinyl leukotriene receptor 1 (CYSLTR1), Myc-DDK-tagged |
CNY 7888.00 |
|
| RC207763L2 | Lenti ORF clone of Human cysteinyl leukotriene receptor 1 (CYSLTR1), mGFP tagged |
CNY 5890.00 |
|
| RC207763L3 | Lenti ORF clone of Human cysteinyl leukotriene receptor 1 (CYSLTR1), Myc-DDK-tagged |
CNY 7888.00 |
|
| RC207763L4 | Lenti ORF clone of Human cysteinyl leukotriene receptor 1 (CYSLTR1), mGFP tagged |
CNY 7888.00 |
|
| RG207763 | CYSLTR1 (tGFP-tagged) - Human cysteinyl leukotriene receptor 1 (CYSLTR1) |
CNY 4370.00 |
