PARK7 (NM_007262) Human Untagged Clone
CAT＃: SC115623
PARK7 (untagged)-Human Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1
CNY 2400.00
CNY 2950.00
| Cited in 5 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DJ-1; DJ1; GATD2; HEL-S-67p |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115623 sequence for NM_007262 edited (data generated by NextGen Sequencing)
ATGGCTTCCAAAAGAGCTCTGGTCATCCTGGCTAAAGGAGCAGAGGAAATGGAGACGGTC ATCCCTGTAGATGTCATGAGGCGAGCTGGGATTAAGGTCACCGTTGCAGGCCTGGCTGGA AAAGACCCAGTACAGTGTAGCCGTGATGTGGTCATTTGTCCTGATGCCAGCCTTGAAGAT GCAAAAAAAGAGGGACCATATGATGTGGTGGTTCTACCAGGAGGTAATCTGGGCGCACAG AATTTATCTGAGTCTGCTGCTGTGAAGGAGATACTGAAGGAGCAGGAAAACCGGAAGGGC CTGATAGCCGCCATCTGTGCAGGTCCTACTGCTCTGTTGGCTCATGAAATAGGTTTTGGA AGTAAAGTTACAACACACCCTCTTGCTAAAGACAAAATGATGAATGGAGGTCATTACACC TACTCTGAGAATCGTGTGGAAAAAGACGGCCTGATTCTTACAAGCCGGGGGCCTGGGACC AGCTTCGAGTTTGCGCTTGCAATTGTTGAAGCCCTGAATGGCAAGGAGGTGGCGGCTCAA GTGAAGGCTCCACTTGTTCTTAAAGACTAG Clone variation with respect to NM_007262.4 >OriGene 5' read for NM_007262 unedited
TAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTGGTACCCAACGGGCCG GGGCGCCGCGTCCGCAGGAAGAGGCGCGGGGTGCAGGCTTGTAAACATATAACATAAAAA TGGCTTCCAAAAGAGCTCTGGTCATCCTGGCTAAAGGAGCAGAGGAAATGGAGACGGTCA TCCCTGTAGATGTCATGAGGCGAGCTGGGATTAAGGTCACCGTTGCAGGCCTGGCTGGAA AAGACCCAGTACAGTGTAGCCGTGATGTGGTCATTTGTCCTGATGCCAGCCTTGAAGATG CAAAAAAAGAGGGACCATATGATGTGGTGGTTCTACCAGGAGGTAATCTGGGCGCACAGA ATTTATCTGAGTCTGCTGCTGTGAAGGAGATACTGAAGGAGCAGGAAAACCGGAAGGGCC TGATAGCCGCCATCTGTGCAGGTCCTACTGCTCTGTTGGCTCATGAAATAGGTTTTGGAA GTAAAGTTACAACACACCCTCTTGCTAAAGACAAAATGATGAATGGAGGTCATTACACCT ACTCTGAGAATCGTGTGGAAAAAGACGGCCTGATTCTTACAAGCCGGGGGCCTGGGACCA GCTTCGAGTTTGCGCTTGCAATTGTTGAAGCCCTGAATGGCAAGGAGGTGGCGGCTCAAG TGAAGGCTCCACTTGTTCTTAAAGACTAGAGCAGCGAACTGCGACGATCACTTAGAGAAA CAGGCCGTTAGGAATCCATTCTCACTGTGNTCGCTCTAAACAACAGTGNANGTTTATGTG TTCAGAAGTCGCTGTCCTTACTACTTTGGCGNAGTNTGGGAGTCACACTACCAGAGATTT CTCACCTACAATTGTGTCTATACTTTCTAGGCCTTGNTGCAGAATAAACAGGNCATTTAG CNNNNNAAAAANNAAANNAANNAAAAAANAA >OriGene 3' read for NM_007262 unedited
GGGGGGGGGTGGTGTTNTATTNAATATTTTACATATCAAACCNNNGGANNGGTGNAGGAC GCCTGTTTTATCCTGTTTTACAGGGNCTTANAATGTATAGACACAATTTGTAGGGCTGAN AAATCTCTGTGTAGTTGTGACTTCCATACTTCCGCAAAATAGTAAGGACAGCGACTTCTG AACACATTAACCTACCACTGTTTTGTTTAGAGCGAACACAGTGAGAATGGATTCCTAACG GCCTGTTTCTCTAAGTGATCGTCGCAGTTCGCTGCTCTAGTCTTTAAGAACAAGTGGAGC CTTCACTTGAGCCGCCACCTCCTTGCCATTCAGGGCTTCAACAATTGCAAGCGCAAACTC GAAGCTGGTCCCAGGCCCCCGGCTTGTAAGAATCAGGCCGTCTTTTTCCACACGATTCTC AGAGTAGGTGTAATGACCTCCATTCATCATTTTGTCTTTAGCAAGAGGGTGTGTTGTAAC TTTACTTCCAAAACCTATTTCATGAGCCAACAGAGCAGTAGGACCTGCACAGATGGCGGC TATCAGGCCCTTCCGGTTTTCCTGCTCCTTCAGTATCTCCTTCACAGCAGCAGACTCAGA TAAATTCTGTGCGCCCAGATTACCTCCTGGTAGAACCACCACATCATATGGTCCCTCTTT TTTTGCATCTTCAAGGCTGGCATCAGGACAAATGACCACATCACGGCTACACTGTACTGG GTCTTTTCCAGCCAGGCCTGCAACGGTGACCTTAATCCCAGCTCGCCTTATGACATCTAC AGGGATGACCGTCTCCATTTCCCTCTGCTCCCTTAGCCAGGATGACCACCAGCTCTATTT GGAACCCATTTTTATGTTATATGTTTACAAAGCCTGCACCCCGCGCCTTTTTCTGCCGAC GCGGTGCCCCCGCCCGTTGGGTACCACCCTCCTGCCCTAATTAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_007262 |
| Insert Size | 1000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007262.3, NP_009193.2 |
| RefSeq Size | 906 bp |
| RefSeq ORF | 570 bp |
| Locus ID | 11315 |
| UniProt ID | Q99497 |
| Domains | DJ-1_PfpI |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Parkinson's disease |
| Gene Summary | The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. |
Citations (5)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
DJ-1-Dependent Regulation of Oxidative Stress in the Retinal Pigment Epithelium (RPE)
,null,
PLoS ONE
,PubMed ID 23844142
[PARK7]
|
|
DAMTC regulates cytoskeletal reorganization and cell motility in human lung adenocarcinoma cell line: an integrated proteomics and transcriptomics approach
,null,
Cell Death & Disease
,PubMed ID 23059821
[PARK7]
|
|
DJ-1 promotes invasion and metastasis of pancreatic cancer cells by activating SRC/ERK/uPA
,Xiangyi He, Zhong Zheng, Jianfang Li, Qiwen Ben, Jun Liu, Jianian Zhang, Jun Ji, Beiqin Yu, Xuehua Chen, Liping Su, Lin Zhou, Bingya Liu, and Yaozong Yuan,
Carcinogenesis, Mar 2012; 33: 555 - 562.
[PARK7]
|
|
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
,Cristofol Vives-Bauza, Chun Zhou, Yong Huang, Mei Cui, Rosa L.A. de Vries, Jiho Kim, Jessica May, Maja Aleksandra Tocilescu, Wencheng Liu, Han Seok Ko, Jordi Magrané, Darren J. Moore, Valina L. Dawson, Regis Grailhe, Ted M. Dawson, Chenjian Li, Kim Tieu, and Serge Przedborski,
PNAS, Dec 2009; 10.1073/pnas.0911187107
[PARK7]
|
|
The 1p-encoded protein stathmin and resistance of malignant gliomas to nitrosoureas
,TT Ngo, T Peng, XJ Liang, O Akeju, S Pastorino, W Zhang, Y Kotliarov, JC Zenklusen, HA Fine, D Maric, PY Wen, U De Girolami, PM Black, WW Wu, RF Shen, NO Jeffries, DW Kang, and JK Park,
J Natl Cancer Inst. 2007 Apr 18;99(8):639-52.
[PARK7]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201645 | PARK7 (Myc-DDK-tagged)-Human Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1 |
CNY 2400.00 |
|
| RC201645L1 | Lenti ORF clone of Human Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1, Myc-DDK-tagged |
CNY 4800.00 |
|
| RC201645L2 | Lenti ORF clone of Human Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1, mGFP tagged |
CNY 5890.00 |
|
| RC201645L3 | Lenti ORF clone of Human Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1, Myc-DDK-tagged |
CNY 4800.00 |
|
| RC201645L4 | Lenti ORF clone of Human Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1, mGFP tagged |
CNY 4800.00 |
|
| RG201645 | PARK7 (tGFP-tagged) - Human Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1 |
CNY 4000.00 |
