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TDP43 (TARDBP) (NM_007375) Human Untagged Clone
CAT＃: SC115570
TARDBP (untagged)-Human TAR DNA binding protein (TARDBP)
CNY 5,488.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 3,600.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ALS10; TDP-43 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115570 sequence for NM_007375 edited (data generated by NextGen Sequencing)
ATGTCTGAATATATTCGGGTAACCGAAGATGAGAACGATGAGCCCATTGAAATACCATCG GAAGACGATGGGACGGTGCTGCTCTCCACGGTTACAGCCCAGTTTCCAGGGGCGTGTGGG CTTCGCTACAGGAATCCAGTGTCTCAGTGTATGAGAGGTGTCCGGCTGGTAGAAGGAATT CTGCATGCCCCAGATGCTGGCTGGGGAAATCTGGTGTATGTTGTCAACTATCCAAAAGAT AACAAAAGAAAAATGGATGAGACAGATGCTTCATCAGCAGTGAAAGTGAAAAGAGCAGTC CAGAAAACATCCGATTTAATAGTGTTGGGTCTCCCATGGAAAACAACCGAACAGGACCTG AAAGAGTATTTTAGTACCTTTGGAGAAGTTCTTATGGTGCAGGTCAAGAAAGATCTTAAG ACTGGTCATTCAAAGGGGTTTGGCTTTGTTCGTTTTACGGAATATGAAACACAAGTGAAA GTAATGTCACAGCGACATATGATAGATGGACGATGGTGTGACTGCAAACTTCCTAATTCT AAGCAAAGCCAAGATGAGCCTTTGAGAAGCAGAAAAGTGTTTGTGGGGCGCTGTACAGAG GACATGACTGAGGATGAGCTGCGGGAGTTCTTCTCTCAGTACGGGGATGTGATGGATGTC TTCATCCCCAAGCCATTCAGGGCCTTTGCCTTTGTTACATTTGCAGATGATCAGATTGCG CAGTCTCTTTGTGGAGAGGACTTGATCATTAAAGGAATCAGCGTTCATATATCCAATGCC GAACCTAAGCACAATAGCAATAGACAGTTAGAAAGAAGTGGAAGATTTGGTGGTAATCCA GGTGGCTTTGGGAATCAGGGTGGATTTGGTAATAGCAGAGGGGGTGGAGCTGGTTTGGGA AACAATCAAGGTAGTAATATGGGTGGTGGGATGAACTTTGGTGCGTTCAGCATTAATCCA GCCATGATGGCTGCCGCCCAGGCAGCACTACAGAGCAGTTGGGGTATGATGGGCATGTTA GCCAGCCAGCAGAACCAGTCAGGCCCATCGGGTAATAACCAAAACCAAGGCAACATGCAG AAGGAGCCAAACCAGGCCTTCGGTTCTGGAAATAACTCTTATAGTGGCTCTAATTCTGGT GCAGCAATTGGTTGGGGATCAGCATCCAATGCAGGGTCGGGCAGTGGTTTTAATGGAGGC TTTGGCTCAAGCATGGATTCTAAGTCTTCTGGCTGGGGAATGTAG Clone variation with respect to NM_007375.3 1082 g=>a >OriGene 5' read for NM_007375 unedited
NGTTAAATTTGTATACACTCCTATAGGCGGCCGCGCAATTCGCACGAGGGTCGGGCTTCC CACACGGCCTACGGGAAAGTAAAAGAGTCTGAATATATTCGGGTAACCGAAGAGAGAACG ATGAGCCCATTGAAATACCATCGGAAGACGATGGGACGGTGCTGCTCTCCACGGTTACAG CCCAGTTTCCAGGGGCGTGTGGGCTTCGCTACAGGAATCCAGTGTCTCAGTGTATGAGAG GTGTCCGGCTGGTAGAAGGAATTCTGCATGCCCCAGATGCTGGCTGGGGAAATCTGGTGT ATGTTGTCAACTATCCAAAAGATAACAAAAGAAAAATGGATGAGACAGATGCTTCATCAG CAGTGAAAGTGAAAAGAGCAGTCCAGAAAACATCCGATTTAATAGTGTTGGGTCTCCCAT GGAAAACAACCGAACAGGACCTGAAAGAGTATTTTAGTACCTTTGGAGAAGTTCTTATGG TGCAGGTCAAGAAAGATCTTAAGACTGGTCATTCAAAGGGGTTTGGCTTTGTTCGTTTTA CGGAATATGAAACACAAGTGAAAGTAATGTCACAGCGACATATGATAGATGGACGATGGT GTGACTGCAAACTTCCTAATTCTAAGCAAAGCCAAGATGAGCCTTTGAGAAGCAGAAAAG TGTTTGTGGGGCGCTGTACAGAGGACATGACTGAGGATGAGCTGCGGGAGTTCTTCTCTC AGTACGGNGATGTGATGGATGTCTTCATCCCCAAGCCATTCAGGGCCTTTGCCTTTGTTA CATTTGCAGATGATCAGATTGCGCAGTCTCTTTGTGGAGAGGACTTGATCATTAAGGAAT CAGCGTTCATTATCCCATGCCGAACCCTAGCACAATAGCATAGAAGTTAGAAAGAGTGGA AGATTNGTG >OriGene 3' read for NM_007375 unedited
GGCACGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTATTTAAATCAGTTTTATTTAA GAATTTCCAACAATGACAACTCTTATAAAAAGCATCCAAGCACAGGACACAGAACTGCAG CAAACAGCATTCTTATGGGTAGCTAACAGACATTAGAACTTCCACCCTTCTTTGAGACAC CTGAGCTCACTGGTGAACTCTGCTTCAAGTCCTCCTGCAAAGCACACCACAAGCTCAGTC CATGTTCTCAGCCCATCAGCTTCAGTTCACATTGCCACACTTACATATCAGTAACAGAAG AGAACACACACCATACAGCATTCACAGCAGTTGACAAAGGGGTAGGGGGAGTACAAGTAT CATTTCACTTAACACATTCATCTAATGTGGGTTATCTAAGAACAAAAACTCACTTAAAAG TCTTCCAACAGATGTGGATGTCCTTTGAATGCAAAAAACATTCGTACATTATTTGCTATC ATTGCTCTCTGCACACTCTCTCACCAAAGCCACAGGATTGAGAGACACATCTCGCCAAGT TAAAAAATATCCATTATGCACCACCAAGTCTCTGCACGCGCTCTCTCCTTTTCTCGCTCA TACTAGCCTTTCATGCCTCGGCACCACCATCAATCCCACACAAGGTTTCAAAAGTTCAGA CAGCCTTCTGGTTCCATATCACAGCCTTGCGTTCATAGCGTTGATACGACTCCATGAAAT ANAGAGTAGCGGATAAAAATGGGACACCCACCGTCAAAGACGCGGCCTGTGATGCGTGAT GACGAATTCTTGATGAGAAAGCTTAGACAGTATCCTATGCAGATATTACACACTACTTCA TGAGNNGCTCCCATAACATTGAATGAAGACTGCGAGATAAGAAGCTCTATGACTTTGGTT GAGGAGACAGGTAAACAACAAGACAACTGGCACTGAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_007375 |
| Insert Size | 3110 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_007375.3, NP_031401.1 |
| RefSeq Size | 4236 bp |
| RefSeq ORF | 1245 bp |
| Locus ID | 23435 |
| UniProt ID | Q13148 |
| Domains | RRM |
| Protein Families | Transcription Factors |
| Gene Summary | HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
TDP-43 Mediates Degeneration in a Novel Drosophila Model of Disease Caused by Mutations in VCP/p97
,Gillian P. Ritson, Sara K. Custer, Brian D. Freibaum, Jake B. Guinto, Dyanna Geffel, Jennifer Moore, Waixing Tang, Matthew J. Winton, Manuela Neumann, John Q. Trojanowski, Virginia M.-Y. Lee, Mark S. Forman, and J. Paul Taylor,
J. Neurosci., Jun 2010; 30: 7729 - 7739
[TARDBP]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210639 | TARDBP (Myc-DDK-tagged)-Human TAR DNA binding protein (TARDBP) |
CNY 3,656.00 |
|
| RC210639L1 | Lenti ORF clone of Human TAR DNA binding protein (TARDBP), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210639L2 | Lenti ORF clone of Human TAR DNA binding protein (TARDBP), mGFP tagged |
CNY 5,890.00 |
|
| RC210639L3 | Lenti ORF clone of Human TAR DNA binding protein (TARDBP), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210639L4 | Lenti ORF clone of Human TAR DNA binding protein (TARDBP), mGFP tagged |
CNY 5,890.00 |
|
| RG210639 | TARDBP (tGFP-tagged) - Human TAR DNA binding protein (TARDBP) |
CNY 4,370.00 |
|
| SC322765 | TARDBP (untagged)-Human TAR DNA binding protein (TARDBP) |
CNY 5,488.00 |
