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IRAK4 (NM_016123) Human Untagged Clone
CAT＃: SC114468
IRAK4 (untagged)-Human interleukin-1 receptor-associated kinase 4 (IRAK4), transcript variant 2
CNY 2,950.00
Product images
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IMD67; IPD1; IRAK-4; NY-REN-64; REN64 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_016123 edited
ATGAACAAACCCATAACACCATCAACATATGTGCGCTGCCTCAATGTTGGACTAATTAGG AAGCTGTCAGATTTTATTGATCCTCAAGAAGGATGGAAGAAGTTAGCTGTAGCTATTAAA AAACCATCTGGTGATGATAGATACAATCAGTTTCACATAAGGAGATTTGAAGCATTACTT CAAACTGGAAAAAGTCCCACTTCTGAATTACTGTTTGACTGGGGCACCACAAATTGCACA GTTGGTGATCTTGTGGATCTTTTGATCCAAAATGAATTTTTTGCTCCTGCGAGTCTTTTG CTCCCAGATGCTGTTCCCAAAACTGCTAATACACTACCTTCTAAAGAAGCTATAACAGTT CAGCAAAAACAGATGCCTTTCTGTGACAAAGACAGGACATTGATGACACCTGTGCAGAAT CTTGAACAAAGCTATATGCCACCTGACTCCTCAAGTCCAGAAAATAAAAGTTTAGAAGTT AGTGATACACGTTTTCACAGTTTTTCATTTTATGAATTGAAGAATGTCACAAATAACTTT GATGAACGACCCATTTCTGTTGGTGGTAATAAAATGGGAGAGGGAGGATTTGGAGTTGTA TATAAAGGCTACGTAAATAACACAACTGTGGCAGTGAAGAAGCTTGCAGCAATGGTTGAC ATTACTACTGAAGAACTGAAACAGCAGTTTGATCAAGAAATAAAAGTAATGGCAAAGTGT CAACATGAAAACTTAGTAGAACTACTTGGTTTCTCAAGTGATGGAGATGACCTCTGCTTA GTATATGTTTACATGCCTAATGGTTCATTGCTAGACAGACTCTCTTGCTTGGATGGTACT CCACCACTTTCTTGGCACATGAGATGCAAGATTGCTCAGGGTGCAGCTAATGGCATCAAT TTTCTACATGAAAATCATCATATTCATAGAGATATTAAAAGTGCAAATATCTTACTGGAT GAAGCTTTTACTGCTAAAATATCTGACTTTGGCCTTGCACGGGCTTCTGAGAAGTTTGCC CAGACAGTCATGACTAGCAGAATTGTGGGAACAACAGCTTATATGGCACCAGAAGCTTTG CGTGGAGAAATAACACCCAAATCTGATATTTACAGCTTTGGTGTGGTTTTACTAGAAATA ATAACTGGACTTCCAGCTGTGGATGAACACCGTGAACCTCAGTTATTGCTAGATATTAAA GAAGAAATTGAAGATGAAGAAAAGACAATTGAAGATTATATTGATAAAAAGATGAATGAT GCTGATTCCACTTCAGTTGAAGCTATGTACTCTGGTGCTAGCCAATGTCGGCATGAAAAG AAAAATAAGAGACCAGACATTAAGAAGGTTCAACAGCTGCTGCAAGAGATGACAGCTTCT TAA >OriGene 5' read for NM_016123 unedited
GTAACGTACAAATTTTGTAATACGAACTCACTATAGGGCGGCCGCGAATTCGCACGAGGG TTCTTCTGTCGCCGGCTTCAGCAGCCCGCGCCCGGGCAGGAATAGAAGATGAACAAACCC ATAACACCATCAACATATGTGCGCTGCCTCAATGTTGGACTAATTAGGAAGCTGTCAGAT TTTATTGATCCTCAAGAAGGATGGAAGAAGTTAGCTGTAGCTATTAAAAAACCATCTGGT GATGATAGATACAATCAGTTTCACATAAGGAGATTTGAAGCATTACTTCAAACTGGAAAA AGTCCCACTTCTGAATTACTGTTTGACTGGGGCACCACAAATTGCACAGTTGGTGATCTT GTGGATCTTTTGATCCAAAATGAATTTTTTGCTCCTGCGAGTCTTTTGCTCCCAGATGCT GTTCCCAAAACTGCTAATACACTACCTTCTAAAGAAGCTATAACAGTTCAGCAAAAACAG ATGCCTTTCTGTGACAAAGACAGGACATTGATGACACCTGTGCAGAATCTTGAACAAAGC TATATGCCACCTGACTCCTCAAGTCCAGAAAATAAAAGTTTAGAAGTTAGTGATACACGT TTTCACAGTTTTTCATTTTATGAATTGAAGAATGTCACAAATAACTTTGATGAACGACCC ATTTCTGTTGGTGGTAATAAAATGGGAGAGGGAGGATTTGGAGTTGTATATAAAGGCTAC GTAAATAACACAACTGTGGCAGTGAAGAAGCTTGCAGCAATGGTTGACATTACTACTGGA GAACTGAAACAGCAGTTTGATCAAGAAATAAAAAGTATGGCAAAGTGTCAACATGAAAAC TTAGTAGAACTACTTGGTTTCTCAAGTGATGGAGATGACCTCTGCTTAGTATATGTTTAC ATGCCTAT >OriGene 3' read for NM_016123 unedited
GGGGGAACTTGGGGGGATGNNGNCNCCTGNGTACCTGATTGTATTTATTTATGACTGGAG AGTCTCACTACTGTACACCCAGGGCTGAAGTGCCCCCGCCCCCCCCCTTTTTTTTTTTTT TTTTTGGGGGNGNCNCNNNNTGNNNCCCAGCCTGAACNCCCANATGGTGGGACTACAGGT GTCCACCACCACGCTCGTCTAATTTTTGTATTTTTAGAAAATTTGTTGTTTTACCATGTT GGCCAGGCCGGTCTTTTTCTGTTGACCTCAGGTGATCTGCCTGCCTCGGCCCCCCAAAGT GCTGGGATTTACGGGTATGAGCCACCACATCCAGCCAATGTGACCCATTATCTCTTTTTT TTTTATATCAAAAGTCCCGCACAGAACAAATTGATTCTCATACTGAGGATCATGCAAAGC TGAAATCCAGGTGTCAGCCCAGGCTGTGGTTATCATCTGAAGCTTGGAGTACTCTTTTAA GCTGACTCAGATTTTCGGGAGAATTCACTTCCTTGGGGTTGCAACTGAGGCCCCAATTTT TTTTCCTGCTTGCTAGACACTGGGAGGAAGGGCTCATCTCCTAGAGGCCACCTTTAGGTT TTAGCCAATGGGGCCCTCTCACATACTTCTTTAGGCTTACCAGGGAAATTCTTCTTGCAA GGGTTGCATTGATTAATGGAGGCCCTTTAAAAGTCCGAAAGGGAGTGGTTTGGCACCTTA ACGGCTGGGCCAAATTCCCTGAACCGTGGGCTGCAACTAATTCTTATGGGGGCGGGTAAA TTTGGCGGCCCTCATAAGGGATATTTCTTAATGGGGGAAAAAGACAATCTGTGGCCCTTA TTTTCGAAGTTCCCGGTCAAACGAATTTTGTCAACTGATGCAATAAAACTTTAACACGAG GGATTCTCTTCCATTTAACGACGGAGTTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_016123 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_016123.1, NP_057207.1 |
| RefSeq Size | 2817 bp |
| RefSeq ORF | 1383 bp |
| Locus ID | 51135 |
| UniProt ID | Q9NWZ3 |
| Domains | DEATH, pkinase, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Apoptosis, Neurotrophin signaling pathway, Toll-like receptor signaling pathway |
| Gene Summary | This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 13 all encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203041 | IRAK4 (Myc-DDK-tagged)-Human interleukin-1 receptor-associated kinase 4 (IRAK4), transcript variant 2 |
CNY 3,656.00 |
|
| RC203041L1 | Lenti ORF clone of Human interleukin-1 receptor-associated kinase 4 (IRAK4), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203041L2 | Lenti ORF clone of Human interleukin-1 receptor-associated kinase 4 (IRAK4), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC203041L3 | Lenti ORF clone of Human interleukin-1 receptor-associated kinase 4 (IRAK4), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203041L4 | Lenti ORF clone of Human interleukin-1 receptor-associated kinase 4 (IRAK4), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG203041 | IRAK4 (tGFP-tagged) - Human interleukin-1 receptor-associated kinase 4 (IRAK4), transcript variant 2 |
CNY 4,370.00 |
|
| SC320873 | IRAK4 (untagged)-Human interleukin-1 receptor-associated kinase 4 (IRAK4), transcript variant 2 |
CNY 2,950.00 |
|
| SC323327 | IRAK4 (untagged)-Kinase deficient mutant (K213M) of Human interleukin-1 receptor-associated kinase 4 (IRAK4), transcript variant 2 |
CNY 3,656.00 |
|
| SC323644 | IRAK4 (untagged)-Kinase deficient mutant (K213M) of Human interleukin-1 receptor-associated kinase 4 (IRAK4), transcript variant 2 |
CNY 3,656.00 |
