PRKAG2 (NM_016203) Human Untagged Clone
CAT＃: SC114421
PRKAG2 (untagged)-Human protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant a
CNY 4248.00
CNY 9220.00
Product images
CNY 6281.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AAKG; AAKG2; CMH6; H91620p; WPWS |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC114421 sequence for NM_016203 edited (data generated by NextGen Sequencing)
ATGGGAAGCGCGGTTATGGACACCAAGAAGAAAAAAGATGTTTCCAGCCCCGGCGGGAGC GGCGGCAAGAAAAATGCCAGCCAGAAGAGGCGTTCGCTGCGCGTGCACATTCCGGACCTG AGCTCCTTCGCCATGCCGCTCCTGGACGGAGACCTGGAGGGTTCCGGAAAGCATTCCTCT CGAAAGGTGGACAGCCCCTTCGGCCCGGGCAGCCCCTCCAAAGGGTTCTTCTCCAGAGGC CCCCAGCCCCGGCCCTCCAGCCCCATGTCTGCACCTGTGAGGCCCAAGACCAGCCCCGGC TCTCCCAAAACCGTGTTCCCGTTCTCCTACCAGGAGTCCCCGCCACGCTCCCCTCGACGC ATGAGCTTCAGTGGGATCTTCCGCTCCTCCTCCAAAGAGTCTTCCCCCAACTCCAACCCT GCTACCTCGCCCGGGGGCATCAGGTTTTTCTCCCGCTCCAGAAAAACCTCCGGCCTCTCC TCCTCTCCGTCAACACCCACCCAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTAT AAGCACGAGCCTGAACGGTTAGAGAATCGCATCTATGCCTCGTCTTCCCCCCCGGACACA GGGCAGAGGTTCTGCCCGTCTTCCTTCCAGAGCCCGACCAGGCCTCCACTGGCATCACCG ACACACTATGCTCCCTCCAAAGCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCC GGCATGCTGGAGAAGCTGGAGTTCGAGGACGAAGCAGTAGAAGACTCAGAAAGTGGTGTT TACATGCGATTCATGAGGTCACACAAGTGTTATGACATCGTTCCAACCAGTTCAAAGCTT GTTGTCTTTGATACTACATTACAAGTTAAAAAGGCCTTCTTTGCTTTGGTAGCCAACGGT GTCCGAGCAGCGCCACTGTGGGAGAGTAAAAAACAAAGTTTTGTAGGAATGCTAACAATT ACAGATTTCATAAATATACTACATAGATACTATAAATCACCTATGGTACAGATTTATGAA TTAGAGGAACATAAAATTGAAACATGGAGGGAGCTTTATTTACAAGAAACATTTAAGCCT TTAGTGAATATATCTCCAGATGCAAGCCTCTTCGATGCTGTATACTCCTTGATCAAAAAT AAAATCCACAGATTGCCCGTTATTGACCCTATCAGTGGGAATGCACTTTATATACTTACC CACAAAAGAATCCTCAAGTTCCTCCAGCTTTTTATGTCTGATATGCCAAAGCCTGCCTTC ATGAAGCAGAACCTGGATGAGCTTGGAATAGGAACGTACCACAACATTGCCTTCATACAT CCAGACACTCCCATCATCAAAGCCTTGAACATATTTGTGGAAAGACGAATATCAGCTCTG CCTGTTGTGGATGAGTCAGGAAAAGTTGTAGATATTTATTCCAAATTTGATGTAATTAAT CTTGCTGCTGAGAAAACATACAATAACCTAGATATCACGGTGACCCAGGCCCTTCAGCAC CGTTCACAGTATTTTGAAGGTGTTGTGAAGTGCAATAAGCTGGAAATACTGGAGACCATC GTGGACAGAATAGTAAGAGCTGAGGTCCATCGGCTGGTGGTGGTAAATGAAGCAGATAGT ATTGTGGGTATTATTTCCCTGTCGGACATTCTGCAAGCCCTGATCCTCACACCAGCAGGT GCCAAACAAAAGGAGACAGAAACGGAGTGA Clone variation with respect to NM_016203.3 >OriGene 5' read for NM_016203 unedited
ATTTTGTTTACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGAGGAAGGACGCTTGA ATTCGGCGCTTCGGCGGCGGCGGCGGCCGCGCGAGTTCCCTGCTCACCCTCCCTCTCCGC GGAAGTCCCCACGAGGTGGCTTCAGGGTGTAACAGAGCGCGCGGCTCCAGTCCGAAGGCA GCGGCCGGGGGAGGGAAGGAGGGGACCGAACCCCCGAGGAGTTTCGCAGAATCAACTTCT GGTTAGAGTTATGGGAAGCGCGGTTATGGACACCAAGAAGAAAAAAGATGTTTCCAGCCC CGGCGGGAGCGGCGGCAAGAAAAATGCCAGCCAGAAGAGGCGTTCGCTGCGCGTGCACAT TCCGGACCTGAGCTCCTTCGCCATGCCGCTCCTGGACGGAGACCTGGAGGGTTCCGGAAA GCATTCCTCTCGAAAGGTGGACAGCCCCTTCGGCCCGGGCAGCCCCTCCAAAGGGTTCTT CTCCAGAGGCCCCCAGCCCCGGCCCTCCAGCCCCATGTCTGCACCTGTGAGGCCCAAGAC CAGCCCCGGCTCTCCCAAAACCGTGTTCCCGTTCTCCTACCAGGAGTCCCCGCCACGCTC CCCTCGACGCATGAGCTTCAGTGGGATCTTCCGCTCCTCCTCCAAGAGTCTTCCCCCAAC TCCAACCCTGCTACCTCGCCCGGGGGCATTAAGTTTTTTCTCCCGCTCCAGAAAACCTTC GGGCTCTTCTCCTCTCCGGCACCACCACCCAGTGACCAAGCAGCACACGTTTCCCCTGGA ATCCCTAAGCACGAGCCTCGACCGGTAAGAGATCGCATTTATGCCTCGGTTTCCCCCCGG ACACAGGGCAACAGTTTTGCCCT >OriGene 3' read for NM_016203 unedited
CGGGGGACCTTTGGNNGATGGCAACTTNCCAGTTCCAGGNANAGCACTGGGGNAGGGTCA CAGGATGCCACCCGGGTTCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTC GAGTTTTTTTTTTTTTTTTTTCATGGATGTGGTGAAGTTTATTCCACCAAAAGATGTGTA AAAAAATTGCATGAAAGTAAAAATAAATAAAGCTGTTGTAAAGCAGCCTCGTTGACACGG TAGCCCAGAACAAAACACTTACGTGTAAAAGTGTCATTACAATTTTAAAGTAATTATTTA TATTCAAATTACAACTTTTTGACAAATCTAAAGAAAACAAACTGATTTGGTAAAAGGTTC AAAGACTTCCACATTCAAGCTCGGTGTTGTTTCACACGCGTGCGCCCCGGCTGCGGCGGT GACATATTGCTGTATTCGGACATAAGGCACTGTGATCTGAACATACCGTGCACTCACCTT ATGCCACATCACCTGTTCCATACCAGTGAATTCTTTGAAATGAAAAATAATGAAAACTTC AGGACACAGTGCACTTTAATGACATACAGCATTTAAAATCCTTCAGACAAAGGTCTGAAA ACAGTCTTTTAATGCAAGCCTGAATCTTCAAGCACATAAAATCTTTCTTTTTTAAGCTTA ATTTCAACATCACTGGAAGAAATACCTATTGTTAAAACCCTGATATACATTCTTAACCAC TTGCAACCCGTGGTCATGAGGCCAAACGTGGCCCAGAAACTTTTTTCAAATTCTCCTCCT AGGGCGTCTACATTTCCGGGGGGGCACCTCCGTTTCTGTCTCCTTTTGTTTGGCACCTGG TGGTGTGAGAATCAAGCCTTGCAAAATGTTCAAAAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_016203 |
| Insert Size | 2600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_016203.2, NP_057287.2 |
| RefSeq Size | 2062 bp |
| RefSeq ORF | 1710 bp |
| Locus ID | 51422 |
| UniProt ID | Q9UGJ0 |
| Domains | CBS |
| Protein Families | Druggable Genome |
| Protein Pathways | Adipocytokine signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin signaling pathway |
| Gene Summary | AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jan 2015] Transcript Variant: This variant (a) represents the longest transcript and encodes the longest isoform (a, also referred to as PRKAG2-a). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224953 | PRKAG2 (Myc-DDK-tagged)-Human protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant a |
CNY 4232.00 |
|
| RC224953L1 | Lenti ORF clone of Human protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant a, Myc-DDK-tagged |
CNY 6632.00 |
|
| RC224953L2 | Lenti ORF clone of Human protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant a, mGFP tagged |
CNY 6940.00 |
|
| RC224953L3 | Lenti ORF clone of Human protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant a, Myc-DDK-tagged |
CNY 6940.00 |
|
| RC224953L4 | Lenti ORF clone of Human protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant a, mGFP tagged |
CNY 6940.00 |
|
| RG224953 | PRKAG2 (tGFP-tagged) - Human protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant a |
CNY 5832.00 |
