UPB1 (NM_016327) Human Untagged Clone
CAT＃: SC114316
UPB1 (untagged)-Human ureidopropionase, beta (UPB1)
CNY 3656.00
CNY 7220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BUP1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC114316 sequence for NM_016327 edited (data generated by NextGen Sequencing)
ATGGCGGGCGCTGAGTGGAAGTCGCTGGAGGAATGCTTGGAGAAGCACCTGCCGCTCCCC GACTTGCAGGAAGTGAAGCGCGTTCTCTATGGCAAGGAACTCAGGAAGCTTGATCTGCCC AGGGAAGCTTTCGAAGCTGCCTCCAGAGAAGACTTTGAACTGCAGGGATATGCCTTTGAA GCAGCGGAGGAGCAGCTGAGACGACCCCGCATTGTGCACGTGGGGCTGGTTCAGAACAGA ATCCCCCTCCCCGCAAATGCCCCTGTGGCAGAACAGGTCTCTGCCCTTCATAGACGCATA AAGGCTATCGTAGAGGTGGCTGCAATGTGTGGAGTCAACATCATCTGTTTCCAGGAAGCA TGGACTATGCCCTTTGCCTTCTGTACGAGAGAGAAGCTTCCTTGGACAGAATTTGCTGAG TCAGCAGAGGATGGGCCCACCACCAGATTCTGTCAGAAGCTGGCGAAGAACCATGACATG GTGGTGGTGTCTCCCATCCTGGAACGAGACAGCGAGCATGGGGATGTTTTGTGGAATACA GCCGTGGTGATCTCCAATTCCGGAGCAGTCCTGGGAAAGACCAGGAAAAACCACATCCCC AGAGTGGGTGATTTCAACGAGTCAACTTACTACATGGAGGGAAACCTGGGCCACCCCGTG TTCCAGACGCAGTTCGGAAGGATCGCGGTGAACATTTGCTACGGGCGGCACCACCCCCTC AACTGGCTTATGTACAGCATCAACGGGGCTGAGATCATCTTCAACCCCTCGGCCACGATA GGAGCACTCAGCGAGTCCCTGTGGCCCATCGAGGCCAGAAACGCAGCCATTGCCAATCAC TGCTTCACCTGCGCCATCAATCGAGTGGGCACCGAGCACTTCCCGAACGAGTTTACCTCG GGAGATGGAAAGAAAGCTCACCAGGACTTTGGCTACTTTTATGGCTCGAGCTATGTGGCA GCCCCTGACAGCAGCCGGACTCCTGGGCTGTCCCGTAGCCGGGATGGACTGCTAGTTGCT AAGCTCGACCTAAACCTCTGCCAGCAGGTGAATGATGTCTGGAACTTCAAGATGACGGGC AGGTATGAGATGTACGCACGGGAGCTCGCCGAAGCTGTCAAGTCCAACTACAGCCCCACC ATCGTGAAAGAGTAG Clone variation with respect to NM_016327.2 >OriGene 5' read for NM_016327 unedited
NNNNGGGGGGNNNNNNNNCCCCCNNNNNNNNNNGGGTCCAGAAATTGTNATACGACTCAC TATAGGCGGCCGCGAATTCGCACCAGCGGGCAAAGGCAGGCAGTTCGTGCGCGGACACAA GCACTGGCGGACCGTGGCCATGGCGGGCGCTGAGTGGAAGTCGCTGGAGGAATGCTTGGA GAAGCACCTGCCGCTCCCCGACTTGCAGGAAGTGAAGCGCGTTCTCTATGGCAAGGAACT CAGGAAGCTTGATCTGCCCAGGGAAGCTTTCGAAGCTGCCTCCAGAGAAGACTTTGAACT GCAGGGATATGCCTTTGAAGCAGCGGAGGAGCAGCTGAGACGACCCCGCATTGTGCACGT GGGGCTGGTTCAGAACAGAATCCCCCTCCCCGCAAATGCCCCTGTGGCAGAACAGGTCTC TGCCCTTCATAGACGCATAAAGGCTATCGTAGAGGTGGCTGCAATGTGTGGAGTCAACAT CATCTGTTTCCAGGAAGCATGGACTATGCCCTTTGCCTTCTGTACGAGAGAGAAGCTTCC TTGGACAGAATTTGCTGAGTCAGCAGAGGATGGGCCCACCACCAGATTCTGTCAGAAGCT GGCGAAGAACCATGACATGGTGGTGGTGTCTCCCATCCTGNAACGAGACAGCGAGCATGG NGATGTTNTGTGGAATACAGCCGTGGTGATCTCCAATTCCGGAGCAGTCCTGNGAAAGAC CAGAANAAACCACANTCCCAGAGTGGGTGATTTCAACGAGTCAACTTACTACATGGAGGG GAAACCTGNGCCACCCCGTGTTCCANAACGCATTCNGAAAGGAATCGCGTGAAACATTTG CTACGGGCGGGCACACCCCCNTCACTGGCTTATGTACAGCATCAAACGGGGCTGAGATCA TTTTCAACCCTTCGNCCACCATAGGAGCACTCAGCCGAGTCCCTTGTGGGCCAT >OriGene 3' read for NM_016327 unedited
NNTTTTTGACTCATGCCCCGCGGNCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTT TTTTTTTAGGGGATATATTGAGATTTATTGCAAGGAATTGACTTCAGTGATTGTAGGAGC TGGCTAGTCATGTCTAAACTCTGTGAGGCAGGCTATCAAAAGGGCAGACTGTCAGGAACT CTCGCCAAGCACTGGGCTGCTGTCCTCAGGCAGAATTTCTTCCTCAGGGAAACCCTTAGC TCTGTTCTTTAGGCCTTCTGACTAATCAGGTCAGGCTGACCCAGATTATCTGAGATAATC TCACTTACTTAGTCAATTGGGAATGGACTTCTGTCACATCTACAAAATACCTTCACAGAA ATACCTAGATTAGTGTCTGATTGAATTACTGGTGACTGTGGCCTAGCTAAGCTGACACAT CCAAAGACCATCCGACCCACCACAGCCTTGCTGTAGGCTCAGGGTCTCTGGATCAGCCCT CACCCTCTTCCCACTGGTGTACGGGATGGACAGCATCATCTGCCTAACCTCAAATCCACC TGCACAAGCAGTACCTGGGCATTTTTTTTTTTAGTTGAGGTAAAATTTACATAACAAACA TTCTGAAGTATACAAATTCAGTGGCATTTAGTACATTCACCTCTACCTAGTCCCCAAACA TTTCCAATACCCCAGAAGTAAGCAGCCCCTTACCCATTAAGAAGTCACTCCCCATGCCAC TCTCCCCCTGCCTGGGAATTNTAAAACCAACCTGGACAATGTTATTGGGGAAGAACCTGG ACATGTTAAGCCTGCCACACTTGCTAATCCACTGGGGCAGAGGTGTCTTCCTCACCCCAA AGCAGCACTGAAGCCGGCTACTCTTTCACGATGGTGGGGCTGTANTGGNACTTGACAGNN CTCGCGAAGCTCCGTGCGTACATCTCATACCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_016327 |
| Insert Size | 2170 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_016327.2, NP_057411.1 |
| RefSeq Size | 2167 bp |
| RefSeq ORF | 1155 bp |
| Locus ID | 51733 |
| UniProt ID | Q9UBR1 |
| Domains | CN_hydrolase |
| Protein Pathways | beta-Alanine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Pantothenate and CoA biosynthesis, Pyrimidine metabolism |
| Gene Summary | This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223365 | UPB1 (Myc-DDK-tagged)-Human ureidopropionase, beta (UPB1) |
CNY 3656.00 |
|
| RC223365L3 | Lenti ORF clone of Human ureidopropionase, beta (UPB1), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC223365L4 | Lenti ORF clone of Human ureidopropionase, beta (UPB1), mGFP tagged |
CNY 5890.00 |
|
| RG223365 | UPB1 (tGFP-tagged) - Human ureidopropionase, beta (UPB1) |
CNY 5256.00 |
