HP1 gamma (CBX3) (NM_016587) Human Untagged Clone
CAT＃: SC114184
CBX3 (untagged)-Human chromobox homolog 3 (CBX3), transcript variant 2
CNY 3600.00
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HECH; HP1-GAMMA; HP1Hs-gamma |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_016587 edited
ATGGCCTCCAACAAAACTACATTGCAAAAAATGGGAAAAAAACAGAATGGAAAGAGTAAA AAAGTTGAAGAGGCAGAGCCTGAAGAATTTGTCGTGGAAAAAGTACTAGATCGACGTGTA GTGAATGGGAAAGTGGAATATTTCCTGAAGTGGAAGGGATTTACAGATGCTGACAATACT TGGGAACCTGAAGAAAATTTAGATTGTCCAGAATTGATTGAAGCGTTTCTTAACTCTCAG AAAGCTGGCAAAGAAAAAGATGGTACAAAAAGAAAATCTTTATCTGACAGTGAATCTGAT GACAGCAAATCAAAGAAGAAAAGAGATGCTGCTGACAAACCAAGAGGATTTGCCAGAGGT CTTGATCCTGAAAGAATAATTGGTGCCACAGACAGCAGTGGAGAATTGATGTTTCTCATG AAATGGAAAGATTCAGATGAGGCAGACTTGGTGCTGGCGAAAGAGGCAAATATGAAGTGT CCTCAAATTGTAATTGCTTTTTATGAAGAGAGACTAACTTGGCATTCTTGTCCAGAAGAT GAAGCTCAATAA >OriGene 5' read for NM_016587 unedited
GATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTTGGGGACCA CCGGGCGCCACGCCGCGAACGTAATAGCTCTTCAAGTCTGCAATAAAAAATGGCCTCCAA CAAAACTACATTGCAAAAAATGGGGAAAAAAACAGAATGGAAAGAGTAAAAAAGTTGAAG AGGCAGAGCCTGAAGAATTTGTCGTGGAAAAAGTACTAGATCGACGTGTAGTGAATGGGA AAGTGGAATATTTCCTGAAGTGGAAGGGATTTACAGATGCTGACAATACTTGGGAACCTG AAGAAAATTTAGATTGTCCAGAATTGATTGAAGCGTTTCTTAACTCTCAGAAAGCTGGCA AAGAAAAAGATGGTACAAAAAGAAAATCTTTATCTGACAGTGAATCTGATGACAGCAAAT CAAAGAAGAAAAGAGATGCTGCTGACAAACCAAGAGGATTTGCCAGAGGTCTTGATCCTG AAAGAATAATTGGTGCCACAGACAGCAGTGGAGAATTGATGTTTCTCATGAAATGGAAAG ATTCAGATGAGGCAGACTTGGTGCTGGCGAAAGAGGCAAATATGAAGTGTCCTCAAATTG TAATTGCTTTTTATGAAGAGAGACTAACTTGGCATTCTTGTCCAGAAGATGAAGCTCAAT AATTGTTCACATTGGTCTTTTATATATATTTATATATATATATAAAAATTGGGTCTTAGA TTTTGATTTACTAGTGTGACAAAATAACTACATCCTAATGAAAAATCAAGTTGATATGTT TTGTTTGAAAGTANCGTGGAAAGAAGTGNTGGNGGGTTTTTTGCATCCATAGCACTGGTT ACTTTTGACAAATAATAANNAGCTTCTGTAGTTGCTTCCTTTATCAGAAAAGACATTTGA TACATGGTATATCATTTCCTCTTCATT >OriGene 3' read for NM_016587 unedited
CGGCCGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTTTTTGCATAAAGGAATATAAA ACTATTTATTAACCACTGTTCACCAGTATTTACAATAAAGTAAACAATATACAGTTGGAT AACATTTTGATTACTACAAAGTTGTTCTTCCTGGCTTTTGCTGAACCAGTAAAGCAAACT CAAGATTGAGCCTCCATGTAATGAATTGGGGTAAAGAAAAAACATGCAGGTCAATAGGTT AGGTTACAAAAGGTTGTTCACACATTTATGACAGCAGGTCCTAAACTGCCAACACCTCTA ACCATCTGATTAGGTTTCTATGAGCCAAGTCTTACATATTCCATTCATCATGACCTTTTA GTCAATGTAGCAACAGGGATTCCAACATTTTGCTAAGGAATGGCCCGCTAGGGAAACTTT TAAATGTTCATTTAACTTAGTTTTGTTTAGCTAGTTAAAACACACTAGCATTTGTCTAGT TTCCTCATCTGGATGAGGAAACCTGCTGTGATGGCAGTGATAAAATTTTTCCTTTTAGGA ATTTTGCAAATAAACCACTGCAATTATAGACACTTTAAAATTATCCAATTTAAATTGTCC TATCTAGAATTACTTATTTCACTTGAAATGTATGGTTTCAGGAAAATTTTCAATTTAACT TGAAGGGATTATCTCTTATTTTGCTTGGAATAATGGCATCTCAGAAACATGGGTCTACCT GTGATTTTTTTGTTTGGGTGAATGCTTAAAAACAAAAAAAATTACATATGCATTTTATGG ATACACACACACACCCACACCCACACACAAAAAACACGTAATAAATCTAAAATGGTCCTT AGGCTCATGAGAACACAGTTTGACTGAGTATGACATTGACCTTCCCCCACATTAAAAACT GTTCTCTATGAGAGGAATGATTACATGGTTCAAAGTCTTTCTGAAAGGACACTCCGAGCT TATTATTGTC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_016587 |
| Insert Size | 1790 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_016587.2, NP_057671.2 |
| RefSeq Size | 1851 bp |
| RefSeq ORF | 552 bp |
| Locus ID | 11335 |
| UniProt ID | Q13185 |
| Domains | CHROMO |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011] Transcript Variant: This variant (2) contains an alternate 5' exon but encodes the same protein as transcript variant 1. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220388 | CBX3 (Myc-DDK-tagged)-Human chromobox homolog 3 (CBX3), transcript variant 2 |
CNY 3600.00 |
|
| RC220388L3 | Lenti ORF clone of Human chromobox homolog 3 (CBX3), transcript variant 2, Myc-DDK-tagged |
CNY 5890.00 |
|
| RC220388L4 | Lenti ORF clone of Human chromobox homolog 3 (CBX3), transcript variant 2, mGFP tagged |
CNY 5890.00 |
|
| RG220388 | CBX3 (tGFP-tagged) - Human chromobox homolog 3 (CBX3), transcript variant 2 |
CNY 5200.00 |
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