CCR10 (NM_016602) Human Untagged Clone
CAT＃: SC114153
CCR10 (untagged)-Human chemokine (C-C motif) receptor 10 (CCR10)
CNY 3656.00
CNY 5800.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GPR2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC114153 sequence for NM_016602 edited (data generated by NextGen Sequencing)
ATGGGGACGGAGGCCACAGAGCAGGTTTCCTGGGGCCATTACTCTGGGGATGAAGAGGAC GCATACTCGGCTGAGCCACTGCCGGAGCTTTGCTACAAGGCCGATGTCCAGGCCTTCAGC CGGGCCTTCCAACCCAGTGTCTCCCTGACCGTGGCTGCGCTGGGTCTGGCCGGCAATGGC CTGGTCCTGGCCACCCACCTGGCAGCCCGACGCGCAGCGCGCTCGCCCACCTCTGCCCAC CTGCTCCAGCTGGCCCTGGCCGACCTCTTGCTGGCCCTGACTCTGCCCTTCGCGGCAGCA GGGGCTCTTCAGGGCTGGAGTCTGGGAAGTGCCACCTGCCGCACCATCTCTGGCCTCTAC TCGGCCTCCTTCCACGCCGGCTTCCTCTTCCTGGCCTGTATCAGCGCCGACCGCTACGTG GCCATCGCGCGAGCGCTCCCAGCCGGGCCGCGGCCCTCCACTCCCGGCCGCGCACACTTG GTCTCCGTCATCGTGTGGCTGCTGTCACTGCTCCTGGCGCTGCCTGCGCTGCTCTTCAGC CAGGATGGGCAGCGGGAAGGCCAACGACGCTGTCGCCTCATCTTCCCCGAGGGCCTCACG CAGACGGTGAAGGGGGCGAGCGCCGTGGCGCAGGTGGCCCTGGGCTTCGCGCTGCCGCTG GGCGTCATGGTAGCCTGCTACGCGCTTCTGGGCCGTACGCTGCTGGCCGCCAGGGGGCCC GAGCGCCGGCGTGCGCTGCGCGTCGTGGTGGCTCTGGTGGCGGCCTTCGTGGTGCTGCAG CTGCCCTACAGCCTCGCCCTGCTGCTGGATACTGCCGATCTACTGGCTGCGCGCGAGCGG AGCTGCCCTGCCAGCAAACGCAAGGATGTCGCACTGCTGGTGACCAGCGGCTTGGCCCTC GCCCGCTGTGGCCTCAATCCCGTTCTCTACGCCTTCCTGGGCCTGCGCTTCCGCCAGGAC CTGCGGAGGCTGCTACGGGGTGGGAGCTGCCCCTCAGGGCCTCAACCCCGCCGCGGCTGC CCCCGCCGGCCCCGCCTTTCTTCCTGCTCAGCTCCCACGGAGACCCACAGTCTCTCCTGG GACAACTAG Clone variation with respect to NM_016602.2 696 c=>t >OriGene 3' read for NM_016602 unedited
GGCCTACGGGTACGCGGCCGCCTGGTGGTGGNTAACAACACATTCGCCCTTATGTGGCAA GGCACAGAGGTAGTCCCTTTAGGTCCCTGCCTCTTTCTCAGTGTTCCCCCACCTACTCCC CTTTCCCACGACCCTCAGCCTGCCCCCTCCTCTAGATTCGCAGCCCTAGTTGTCCCAGGA GAGACTGTGGGTCTCCGTGGGAGCTGAGCATGATTTTTGGCGGGGCCGGCGGGGGCAGCC GCGGCGGGGTTGAGGCCCTGAGGGGCAGCTCCCACCCCGTAGCAGCCTCCGCAGGTCCTG GCGGAAGCGCAGGCCCAGGAAGGCGTAGAGAACGGGATTGAGGCCACAGCGGGCGAGGGC CAAGCCGCTGGTCACCAGCAGTGCGACATCCTTGCGTTTGCTGGCAGGGCAGCTCCGCTC GCGCGCAGCCAGTAGATCGGCAGTATCCAGCAGCAGGGCGAGGCTGTAGGGCAGCTGCAG CACCACGAAGGCCGCCACCAGAGCCACCACGACGCGCAGCGCACGCCGGCGCTCGGGCCC CCTGGCGGCCAGCAGCGTACGGCCCAGAAGCGCGTAGCAGGCTACCATGACGCCCAGCGG CAGCGCGAAGCCCAGGGCCACCTGCGCCACGGCGCTCGCCCCCTTCACCGTCTGCGTGAG GCCCTCGGGGAAGATGATGCGACAGCGTCGTTGGCCTTCCCGCTGCCCATCCTGGCTGAA GAGCAGCGCATGCAGCGCCCGGGAGCAGTGACAGCAGCCACACGATGACGGAGACCAAAT GTGCGCGGCCCGGAGTGGAGGGCCCCGGCCCGGCTGGGAGCGCTCGCGCGATGGCCACTT AACGGTCGGGGCTGTTACAGGCCAGGAAGAGAA |
| Restriction Sites | Please inquire |
| ACCN | NM_016602 |
| Insert Size | 1300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_016602.1, NP_057686.1 |
| RefSeq Size | 1244 bp |
| RefSeq ORF | 1089 bp |
| Locus ID | 2826 |
| UniProt ID | P46092 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
| Gene Summary | Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Molecular Interaction of a Potent Nonpeptide Agonist with the Chemokine Receptor CCR8
,PC Jensen, R Nygaard, S Thiele, A Elder, G Zhu, R Kolbeck, S Ghosh, TW Schwartz, and MM Rosenkilde,
Mol Pharmacol. 2007 Aug;72(2):327-40.
[CCR10]
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Other Versions
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| RC222924L2 | Lenti ORF clone of Human chemokine (C-C motif) receptor 10 (CCR10), mGFP tagged |
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| RC222924L3 | Lenti ORF clone of Human chemokine (C-C motif) receptor 10 (CCR10), Myc-DDK-tagged |
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| RC222924L4 | Lenti ORF clone of Human chemokine (C-C motif) receptor 10 (CCR10), mGFP tagged |
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| RG222924 | CCR10 (tGFP-tagged) - Human chemokine (C-C motif) receptor 10 (CCR10) |
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